miltefosine has been researched along with Candidiasis in 5 studies
miltefosine: hexadecyl phosphocholine derivative of cisplatin; did not substantially activate HIV long terminal repeat; less toxic than cisplatin
miltefosine : A phospholipid that is the hexadecyl monoester of phosphocholine.
Candidiasis: Infection with a fungus of the genus CANDIDA. It is usually a superficial infection of the moist areas of the body and is generally caused by CANDIDA ALBICANS. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Miltefosine is an alkylphosphocholine that shows broad-spectrum in vitro antifungal activities and limited in vivo efficacy in mouse models of cryptococcosis." | 3.79 | Synthesis and antifungal activities of miltefosine analogs. ( Agarwal, AK; Chen, YL; Clark, AM; Heitman, J; Jacob, MR; Khan, SI; Li, XC; Pan, X; Ravu, RR, 2013) |
| "Treatment with miltefosine at 1000 μg ml- 1 inhibited biofilm formation by 89% and reduced the metabolic activity of pre-formed C." | 1.42 | Miltefosine is effective against Candida albicans and Fusarium oxysporum nail biofilms in vitro. ( Machado Vila, TV; Rozental, S; Sousa Quintanilha, N, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ravu, RR | 1 |
| Chen, YL | 1 |
| Jacob, MR | 1 |
| Pan, X | 1 |
| Agarwal, AK | 1 |
| Khan, SI | 1 |
| Heitman, J | 1 |
| Clark, AM | 1 |
| Li, XC | 1 |
| Wu, Y | 1 |
| Totten, M | 1 |
| Memon, W | 1 |
| Ying, C | 1 |
| Zhang, SX | 1 |
| Spadari, CC | 1 |
| de Bastiani, FWMDS | 1 |
| Lopes, LB | 1 |
| Ishida, K | 2 |
| Machado Vila, TV | 1 |
| Sousa Quintanilha, N | 1 |
| Rozental, S | 2 |
| Vila, T | 1 |
| Seabra, SH | 1 |
5 other studies available for miltefosine and Candidiasis
| Article | Year |
|---|---|
Synthesis and antifungal activities of miltefosine analogs.
Topics: Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Candida; Candidiasis; Cell Line; C | 2013 |
Topics: Amphotericin B; Antifungal Agents; Candida; Candidiasis; Drug Resistance, Multiple; Drug Therapy, Co | 2020 |
Alginate nanoparticles as non-toxic delivery system for miltefosine in the treatment of candidiasis and cryptococcosis.
Topics: Alginates; Animals; Antifungal Agents; Candida albicans; Candidiasis; Cryptococcosis; Drug Delivery | 2019 |
Miltefosine is effective against Candida albicans and Fusarium oxysporum nail biofilms in vitro.
Topics: Antifungal Agents; Biofilms; Candida albicans; Candidiasis; Fusariosis; Fusarium; Humans; Nail Disea | 2015 |
Miltefosine inhibits Candida albicans and non-albicans Candida spp. biofilms and impairs the dispersion of infectious cells.
Topics: Antifungal Agents; Biofilms; Candida; Candidiasis; Female; Humans; Inhibitory Concentration 50; Male | 2016 |