Page last updated: 2024-10-28

miltefosine and Aspergillosis

miltefosine has been researched along with Aspergillosis in 4 studies

miltefosine: hexadecyl phosphocholine derivative of cisplatin; did not substantially activate HIV long terminal repeat; less toxic than cisplatin
miltefosine : A phospholipid that is the hexadecyl monoester of phosphocholine.

Aspergillosis: Infections with fungi of the genus ASPERGILLUS.

Research Excerpts

ExcerptRelevanceReference
"Miltefosine is an alkylphosphocholine that shows broad-spectrum in vitro antifungal activities and limited in vivo efficacy in mouse models of cryptococcosis."3.79Synthesis and antifungal activities of miltefosine analogs. ( Agarwal, AK; Chen, YL; Clark, AM; Heitman, J; Jacob, MR; Khan, SI; Li, XC; Pan, X; Ravu, RR, 2013)
" fumigatus mouse model, adopting a short-term and long-term oral or intraperitoneal dosing regimen."1.42Efficacy of oleylphosphocholine (OlPC) in vitro and in a mouse model of invasive aspergillosis. ( Bosschaerts, T; Boulet, G; Cos, P; Fortin, A; Maes, L; Paulussen, C, 2015)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Ravu, RR1
Chen, YL1
Jacob, MR1
Pan, X1
Agarwal, AK1
Khan, SI1
Heitman, J1
Clark, AM1
Li, XC1
Dos Reis, TF1
Horta, MAC1
Colabardini, AC1
Fernandes, CM1
Silva, LP1
Bastos, RW1
Fonseca, MVL1
Wang, F1
Martins, C1
Rodrigues, ML1
Silva Pereira, C1
Del Poeta, M1
Wong, KH1
Goldman, GH1
Imbert, S1
Palous, M1
Meyer, I1
Dannaoui, E1
Mazier, D1
Datry, A1
Fekkar, A1
Paulussen, C1
Boulet, G1
Bosschaerts, T1
Cos, P1
Fortin, A1
Maes, L1

Other Studies

4 other studies available for miltefosine and Aspergillosis

ArticleYear
Synthesis and antifungal activities of miltefosine analogs.
    Bioorganic & medicinal chemistry letters, 2013, Sep-01, Volume: 23, Issue:17

    Topics: Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Candida; Candidiasis; Cell Line; C

2013
Screening of Chemical Libraries for New Antifungal Drugs against Aspergillus fumigatus Reveals Sphingolipids Are Involved in the Mechanism of Action of Miltefosine.
    mBio, 2021, 08-31, Volume: 12, Issue:4

    Topics: Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Drug Resistance, Fungal; Fungal Pr

2021
In vitro combination of voriconazole and miltefosine against clinically relevant molds.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:11

    Topics: Antifungal Agents; Aspergillosis; Aspergillus; Candida; Drug Resistance, Fungal; Drug Synergism; Dru

2014
Efficacy of oleylphosphocholine (OlPC) in vitro and in a mouse model of invasive aspergillosis.
    Mycoses, 2015, Volume: 58, Issue:3

    Topics: Animals; Antifungal Agents; Aspergillosis; Aspergillus; Aspergillus fumigatus; Azoles; Disease Model

2015