Page last updated: 2024-10-28

miltefosine and Adenocarcinoma

miltefosine has been researched along with Adenocarcinoma in 6 studies

miltefosine: hexadecyl phosphocholine derivative of cisplatin; did not substantially activate HIV long terminal repeat; less toxic than cisplatin
miltefosine : A phospholipid that is the hexadecyl monoester of phosphocholine.

Adenocarcinoma: A malignant epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
"Miltefosine (hexadecylphosphocholine) is used for topical treatment of breast cancers."3.71MDR1 causes resistance to the antitumour drug miltefosine. ( Grunicke, H; Hofmann, J; Liu, R; Lu, P; Pietro, AD; Rybczynska, M; Sharom, FJ; Spitaler, M; Steinfels, E, 2001)
"The histopathological change from tubular adenocarcinoma to malignant adenoacanthoma might be caused by an overgrowth of the primary epithelial tumor cells or by a real transformation in the morphological characteristics of the tumor, which may occur during repeated transplantation."1.28Effect of miltefosine on transplanted methylnitrosourea-induced mammary carcinoma growing in Fischer 344 rats. ( Amelung, F; Berger, MR; Heyl, P; Reinhardt, M, 1992)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (83.33)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Spruss, T1
Bernhardt, G1
Schönenberger, H1
Engel, J1
Theischen, M1
Bornfeld, N1
Becher, R1
Kellner, U1
Wessing, A1
Rybczynska, M1
Liu, R1
Lu, P1
Sharom, FJ1
Steinfels, E1
Pietro, AD1
Spitaler, M1
Grunicke, H1
Hofmann, J1
Reinhardt, M1
Heyl, P1
Amelung, F1
Berger, MR2
Bishop, FE1
Dive, C1
Freeman, S1
Gescher, A1
Richter, H1
Seelig, MH1
Eibl, H1
Schmähl, D1

Trials

1 trial available for miltefosine and Adenocarcinoma

ArticleYear
Hexadecylphosphocholine may produce reversible functional defects of the retinal pigment epithelium.
    German journal of ophthalmology, 1993, Volume: 2, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents; Colorectal Neoplasms; Electrooculography; Electroretinography

1993

Other Studies

5 other studies available for miltefosine and Adenocarcinoma

ArticleYear
Antitumour activity of miltefosine alone and after combination with platinum complexes on MXT mouse mammary carcinoma models.
    Journal of cancer research and clinical oncology, 1993, Volume: 119, Issue:3

    Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Drug

1993
MDR1 causes resistance to the antitumour drug miltefosine.
    British journal of cancer, 2001, May-18, Volume: 84, Issue:10

    Topics: Adenocarcinoma; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Ca

2001
Effect of miltefosine on transplanted methylnitrosourea-induced mammary carcinoma growing in Fischer 344 rats.
    Arzneimittel-Forschung, 1992, Volume: 42, Issue:10

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Biomarkers, Tumor; Body Weight; Female; Keratins; Ma

1992
Is metabolism an important arbiter of anticancer activity of ether lipids? Metabolism of SRI 62-834 and hexadecylphosphocholine by [31P]-NMR spectroscopy and comparison of their cytotoxicities with those of their metabolites.
    Cancer chemotherapy and pharmacology, 1992, Volume: 31, Issue:2

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Membrane; Cell Survival; Dose-Response Relation

1992
New cytostatics--more activity and less toxicity.
    Cancer treatment reviews, 1990, Volume: 17, Issue:2-3

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Colorectal Neoplasms; Female; Male; Mammary Neoplasm

1990