milrinone and Shock, Cardiogenic studies

Shock, Cardiogenic: Shock resulting from diminution of cardiac output in heart disease.

Research Excerpts

Excerpt	Relevance	Reference
"This study aims to evaluate the difference between dobutamine and milrinone in patients presenting with acute decompensated heart failure (AHF)."	9.41	Meta-analysis Comparing the Efficacy of Dobutamine Versus Milrinone in Acute Decompensated Heart Failure and Cardiogenic Shock. ( Bandyopadhyay, D; Biswas, S; Briasoulis, A; Fonarow, GC; Goel, A; Gupta, R; Lanier, GM; Malik, AH; Naidu, SS, 2023)
"The systemic and pulmonary arterial hemodynamics of 40 patients with severe congestive heart failure were determined during a 24-hour infusion of milrinone (0."	9.07	Effects of a twenty-four-hour milrinone infusion in patients with severe heart failure and cardiogenic shock as a function of the hemodynamic initial condition. ( Hilger, HH; Höpp, HW; Klocke, RK; Kux, A; Mager, G, 1991)
"Milrinone use was associated with a lower adjusted risk of 30 day mortality (hazard ratio = 0."	5.91	Improved mortality and haemodynamics with milrinone in cardiogenic shock due to acute decompensated heart failure. ( Billia, F; Brahmbhatt, DH; Fung, NL; Luis Scolari, F; Luk, A; Mihajlovic, V; Otsuki, M; Overgaard, CB; Rodenas-Alesina, E; Wang, VN, 2023)
"This study aims to evaluate the difference between dobutamine and milrinone in patients presenting with acute decompensated heart failure (AHF)."	5.41	Meta-analysis Comparing the Efficacy of Dobutamine Versus Milrinone in Acute Decompensated Heart Failure and Cardiogenic Shock. ( Bandyopadhyay, D; Biswas, S; Briasoulis, A; Fonarow, GC; Goel, A; Gupta, R; Lanier, GM; Malik, AH; Naidu, SS, 2023)
"The systemic and pulmonary arterial hemodynamics of 40 patients with severe congestive heart failure were determined during a 24-hour infusion of milrinone (0."	5.07	Effects of a twenty-four-hour milrinone infusion in patients with severe heart failure and cardiogenic shock as a function of the hemodynamic initial condition. ( Hilger, HH; Höpp, HW; Klocke, RK; Kux, A; Mager, G, 1991)
"Cardiogenic shock is associated with substantial morbidity and mortality."	3.01	Milrinone as Compared with Dobutamine in the Treatment of Cardiogenic Shock. ( Abdel-Razek, O; Almufleh, A; Bernick, J; Chan, V; Di Santo, P; Fernando, SM; Froeschl, M; Harnett, DT; Hibbert, B; Hutson, J; Jung, RG; Kyeremanteng, K; Labinaz, M; Le May, MR; Marbach, JA; Mathew, R; Merdad, A; Ramirez, FD; Russo, JJ; Simard, T; Wells, GA; Weng, W, 2021)
"Dobutamine induced an increase of cardiac index (2."	2.68	[Differential therapy of cardiogenic shock with dopamine/milrinone in comparison with dopamine/dobutamine]. ( Meissner, A; Schmelzle, T; Simon, R, 1996)
"Milrinone was most effective at reducing mortality and had the lowest incidence of adverse reactions."	2.66	Network Meta-Analysis of the Safety of Drug Therapy for Cardiogenic Shock. ( Chen, X; Lei, J; Liao, X; Qian, L; Zhang, S, 2020)
"Milrinone use was associated with a lower adjusted risk of 30 day mortality (hazard ratio = 0."	1.91	Improved mortality and haemodynamics with milrinone in cardiogenic shock due to acute decompensated heart failure. ( Billia, F; Brahmbhatt, DH; Fung, NL; Luis Scolari, F; Luk, A; Mihajlovic, V; Otsuki, M; Overgaard, CB; Rodenas-Alesina, E; Wang, VN, 2023)
"During the treatment of cardiogenic shock, various continuous infusion drugs are used simultaneously."	1.72	[Chemical Stability after Mixing Continuous Infusion Drugs Used to Treat Cardiogenic Shock]. ( Ishii, T; Izawa, K; Kinoshita, M; Masuda, M; Onoda, T; Sato, N; Tanaka, H; Urano, A, 2022)
" Changes in hemodynamic parameters from baseline and adverse events were also assessed."	1.51	Comparative Effectiveness and Safety Between Milrinone or Dobutamine as Initial Inotrope Therapy in Cardiogenic Shock. ( Aberle, C; Altshuler, D; Lewis, TC; Papadopoulos, J; Piper, GL, 2019)
"He presented with an acute respiratory distress syndrome, a severe pulmonary hypertension was treated initially with mechanical ventilation and nitric oxide."	1.35	[Extracorporeal membranous oxygenation in severe infant pertussis: a case report]. ( Charpentier, A; Couchot, E; Ghez, O; Paut, O; Ughetto, F, 2009)
"Milrinone was effective as a pharmacological bridge to heart transplantation in this patient with terminal and critical heart failure after removal of a left ventricular assist device."	1.31	Clinical experience of milrinone as a pharmacological bridge to heart transplantation. ( Asano, H; Koyanagi, T; Kyo, S; Omoto, R; Ouchi, H; Yokote, Y, 2000)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	7 (25.00)	18.2507
2000's	3 (10.71)	29.6817
2010's	4 (14.29)	24.3611
2020's	14 (50.00)	2.80

Trial	Phase	Enrollment	Study Type	Start Date	Status
Comparison of Milrinone Versus Dobutamine in a Heterogeneous Population of Critically Ill Patients[NCT03207165]	Phase 4	192 participants (Actual)	Interventional	2017-08-30	Completed
Dobutamine Versus Milrinone in Management of Critically Ill Low Cardiac Output Pediatric Patients at Cairo University Children's Hospital[NCT05999487]		40 participants (Anticipated)	Interventional	2023-10-31	Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
Meta-analysis Comparing the Efficacy of Dobutamine Versus Milrinone in Acute Decompensated Heart Failure and Cardiogenic Shock. Current problems in cardiology, 2023, Volume: 48, Issue:8 Topics: Cardiotonic Agents; Dobutamine; Heart Failure; Humans; Milrinone; Randomized Controlled Trials as To	2023
Network Meta-Analysis of the Safety of Drug Therapy for Cardiogenic Shock. Journal of healthcare engineering, 2020, Volume: 2020 Topics: Aged; Disease Progression; Dobutamine; Dopamine; Epinephrine; Female; Hemodynamics; Humans; Male; Mi	2020
Diagnosis and treatment of neonatal hypotension outside the transitional period. Early human development, 2005, Volume: 81, Issue:5 Topics: Adrenal Insufficiency; Dobutamine; Dopamine; Ductus Arteriosus, Patent; Humans; Hypotension; Infant,	2005
[Therapeutic options in cardiogenic shock]. Revista espanola de cardiologia, 1995, Volume: 48, Issue:9 Topics: Amrinone; Angioplasty, Balloon, Coronary; Assisted Circulation; Cardiotonic Agents; Coronary Artery	1995

Article	Year
Implications of Myocardial Infarction on Management and Outcome in Cardiogenic Shock. Journal of the American Heart Association, 2021, 11-02, Volume: 10, Issue:21 Topics: Dobutamine; Heart Arrest; Humans; Milrinone; Myocardial Infarction; Percutaneous Coronary Interventi	2021
Lactate Clearance as a Surrogate for Mortality in Cardiogenic Shock: Insights From the DOREMI Trial. Journal of the American Heart Association, 2022, 03-15, Volume: 11, Issue:6 Topics: Dobutamine; Hospital Mortality; Humans; Lactic Acid; Milrinone; Shock, Cardiogenic	2022
No sex-based difference in cardiogenic shock: A post-hoc analysis of the DOREMI trial. Journal of cardiology, 2022, Volume: 80, Issue:4 Topics: Dobutamine; Female; Heart Arrest; Humans; Male; Milrinone; Myocardial Infarction; Shock, Cardiogenic	2022
Arrhythmic Events and Mortality in Patients With Cardiogenic Shock on Inotropic Support: Results of the DOREMI Randomized Trial. The Canadian journal of cardiology, 2023, Volume: 39, Issue:4 Topics: Arrhythmias, Cardiac; Dobutamine; Humans; Milrinone; Shock, Cardiogenic; Stroke Volume; Ventricular	2023
Milrinone as Compared with Dobutamine in the Treatment of Cardiogenic Shock. The New England journal of medicine, 2021, 08-05, Volume: 385, Issue:6 Topics: Adrenergic beta-Agonists; Aged; Cardiotonic Agents; Comorbidity; Dobutamine; Double-Blind Method; Fe	2021
Milrinone as Compared with Dobutamine in the Treatment of Cardiogenic Shock. The New England journal of medicine, 2021, 08-05, Volume: 385, Issue:6 Topics: Adrenergic beta-Agonists; Aged; Cardiotonic Agents; Comorbidity; Dobutamine; Double-Blind Method; Fe	2021
Milrinone as Compared with Dobutamine in the Treatment of Cardiogenic Shock. The New England journal of medicine, 2021, 08-05, Volume: 385, Issue:6 Topics: Adrenergic beta-Agonists; Aged; Cardiotonic Agents; Comorbidity; Dobutamine; Double-Blind Method; Fe	2021
Milrinone as Compared with Dobutamine in the Treatment of Cardiogenic Shock. The New England journal of medicine, 2021, 08-05, Volume: 385, Issue:6 Topics: Adrenergic beta-Agonists; Aged; Cardiotonic Agents; Comorbidity; Dobutamine; Double-Blind Method; Fe	2021
Impact of baseline beta-blocker use on inotrope response and clinical outcomes in cardiogenic shock: a subgroup analysis of the DOREMI trial. Critical care (London, England), 2021, 08-10, Volume: 25, Issue:1 Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Cardiotonic Agents; Dobutamine; Dose-Response	2021
The association between mean arterial pressure and outcomes in patients with cardiogenic shock: insights from the DOREMI trial. European heart journal. Acute cardiovascular care, 2021, Oct-01, Volume: 10, Issue:7 Topics: Arterial Pressure; Cardiotonic Agents; Dobutamine; Humans; Milrinone; Shock, Cardiogenic	2021
Comparison of Levosimendan and Milrinone for ECLS Weaning in Patients After Cardiac Surgery-A Retrospective Before-and-After Study. Journal of cardiothoracic and vascular anesthesia, 2018, Volume: 32, Issue:5 Topics: Aged; Cardiac Surgical Procedures; Cardiotonic Agents; Extracorporeal Membrane Oxygenation; Female;	2018
[Differential therapy of cardiogenic shock with dopamine/milrinone in comparison with dopamine/dobutamine]. Zeitschrift fur Kardiologie, 1996, Volume: 85, Issue:11 Topics: Aged; Blood Pressure; Cardiotonic Agents; Dobutamine; Dopamine; Dose-Response Relationship, Drug; Dr	1996
Effects of a twenty-four-hour milrinone infusion in patients with severe heart failure and cardiogenic shock as a function of the hemodynamic initial condition. American heart journal, 1991, Volume: 121, Issue:6 Pt 2 Topics: Adult; Aged; Cardiotonic Agents; Drug Evaluation; Female; Heart Failure; Hemodynamics; Humans; Male;	1991

Article	Year
Milrinone as Compared with Dobutamine in the Treatment of Cardiogenic Shock. The New England journal of medicine, 2021, Nov-25, Volume: 385, Issue:22 Topics: Cardiotonic Agents; Dobutamine; Epinephrine; Humans; Milrinone; Shock, Cardiogenic	2021
Milrinone as Compared with Dobutamine in the Treatment of Cardiogenic Shock. The New England journal of medicine, 2021, Nov-25, Volume: 385, Issue:22 Topics: Cardiotonic Agents; Dobutamine; Epinephrine; Humans; Milrinone; Shock, Cardiogenic	2021
Milrinone as Compared with Dobutamine in the Treatment of Cardiogenic Shock. Reply. The New England journal of medicine, 2021, Nov-25, Volume: 385, Issue:22 Topics: Cardiotonic Agents; Dobutamine; Epinephrine; Humans; Milrinone; Shock, Cardiogenic	2021
[Chemical Stability after Mixing Continuous Infusion Drugs Used to Treat Cardiogenic Shock]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2022, Volume: 142, Issue:11 Topics: Dobutamine; Humans; Milrinone; Norepinephrine; Pharmaceutical Preparations; Shock, Cardiogenic	2022
Improved mortality and haemodynamics with milrinone in cardiogenic shock due to acute decompensated heart failure. ESC heart failure, 2023, Volume: 10, Issue:4 Topics: Dobutamine; Heart Failure; Hemodynamics; Humans; Milrinone; Retrospective Studies; Shock, Cardiogeni	2023
Postoperative catecholamine resistance following fetal methamphetamine exposure. Asian cardiovascular & thoracic annals, 2019, Volume: 27, Issue:1 Topics: Amphetamine-Related Disorders; Cardiotonic Agents; Central Nervous System Stimulants; Dopamine; Drug	2019
Comparative Effectiveness and Safety Between Milrinone or Dobutamine as Initial Inotrope Therapy in Cardiogenic Shock. Journal of cardiovascular pharmacology and therapeutics, 2019, Volume: 24, Issue:2 Topics: Aged; Aged, 80 and over; Cardiotonic Agents; Dobutamine; Female; Hemodynamics; Humans; Male; Middle	2019
A neonate with critical congenital heart disease. Pediatric annals, 2014, Volume: 43, Issue:5 Topics: Adrenergic alpha-Agonists; Cardiopulmonary Resuscitation; Cardiotonic Agents; Critical Care; Dopamin	2014
[Extracorporeal membranous oxygenation in severe infant pertussis: a case report]. Annales francaises d'anesthesie et de reanimation, 2009, Volume: 28, Issue:1 Topics: Cardiotonic Agents; Critical Care; Extracorporeal Membrane Oxygenation; Humans; Hypertension, Pulmon	2009
Prolonged high frequency jet ventilation and milrinone therapy following modified Fontan procedure. Anaesthesia, 1994, Volume: 49, Issue:4 Topics: Cardiotonic Agents; Child; Heart Atria; Heart Defects, Congenital; High-Frequency Jet Ventilation; H	1994
[The effect of milrinone for the shock patients after cardiac surgery]. Kyobu geka. The Japanese journal of thoracic surgery, 1999, Volume: 52, Issue:3 Topics: Aged; Cardiac Surgical Procedures; Cardiotonic Agents; Coronary Artery Bypass; Female; Heart Valve P	1999
Dextropropoxyphene-induced cardiogenic shock: treatment with intra-aortic balloon pump and milrinone. Intensive care medicine, 1999, Volume: 25, Issue:3 Topics: Adult; Cardiotonic Agents; Dextropropoxyphene; Drug Overdose; Humans; Intra-Aortic Balloon Pumping;	1999
Clinical experience of milrinone as a pharmacological bridge to heart transplantation. The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi, 2000, Volume: 48, Issue:7 Topics: Adult; Cardiomyopathy, Dilated; Heart Transplantation; Humans; Male; Milrinone; Phosphodiesterase In	2000
[New positive inotropic drugs]. Annales francaises d'anesthesie et de reanimation, 1991, Volume: 10, Issue:1 Topics: Adrenergic Agonists; Amrinone; Cardiotonic Agents; Dopamine; Enoximone; Hemodynamics; Humans; Imidaz	1991

milrinone and Shock, Cardiogenic

Research Excerpts

Research

Studies (28)

Authors

Clinical Trials (2)

Trial Overview

Reviews

Trials

Other Studies

Authors	Studies
Jung, RG	7
Di Santo, P	8
Mathew, R	8
Abdel-Razek, O	7
Parlow, S	6
Simard, T	7
Marbach, JA	6
Gillmore, T	2
Mao, B	3
Bernick, J	3
Theriault-Lauzier, P	1
Fu, A	2
Lau, L	1
Motazedian, P	4
Russo, JJ	5
Labinaz, M	4
Hibbert, B	8
Potter, BJ	1
Gibson, LE	1
Chang, MG	1
Berra, L	1
Kapur, NK	1
Thayer, KL	1
Fernando, SM	4
Froeschl, M	4
Biswas, S	1
Malik, AH	1
Bandyopadhyay, D	1
Gupta, R	1
Goel, A	1
Briasoulis, A	1
Fonarow, GC	1
Lanier, GM	1
Naidu, SS	1
Prosperi-Porta, G	1
Hutson, J	2
Malhotra, N	2
Ramirez, FD	5
Weng, W	2
Cheung, M	1
Hutson, JH	1
Thibert, MJ	1
Nery, PB	1
Nair, GM	1
Onoda, T	1
Kinoshita, M	1
Tanaka, H	1
Izawa, K	1
Urano, A	1
Sato, N	1
Masuda, M	1
Ishii, T	1
Rodenas-Alesina, E	1
Luis Scolari, F	1
Wang, VN	1
Brahmbhatt, DH	1
Mihajlovic, V	1
Fung, NL	1
Otsuki, M	1
Billia, F	1
Overgaard, CB	1
Luk, A	1
Liao, X	1
Qian, L	1
Zhang, S	1
Chen, X	1
Lei, J	1
Harnett, DT	1
Merdad, A	1
Almufleh, A	1
Kyeremanteng, K	1
Wells, GA	2
Chan, V	1
Le May, MR	1
Skanes, S	1
Boczar, KE	1
D'Egidio, G	1
Hawken, S	1
Dick, A	2
So, DY	1
Glover, C	2
McGuinty, C	1
Jacky, A	1
Rudiger, A	1
Krüger, B	1
Wilhelm, MJ	1
Paal, S	1
Seifert, B	1
Spahn, DR	1
Bettex, D	1
Perumal, G	1
Marathe, SP	1
Schlapbach, LJ	1
Morwood, J	1
Venugopal, P	1
Alphonso, N	1
Lewis, TC	1
Aberle, C	1
Altshuler, D	1
Piper, GL	1
Papadopoulos, J	1
Linder, J	1
Dawson, E	1
Williams, P	1
Couchot, E	1
Paut, O	1
Ghez, O	1
Charpentier, A	1
Ughetto, F	1
Seri, I	1
Noori, S	1
Alonso Francia, C	1
Calvo Cebollero, I	1
Diarte de Miguel, JA	1
Gomollón García, JP	1
Placer Peralta, LJ	1
McBride, WT	1
McMurray, TJ	1
Meissner, A	1
Schmelzle, T	1
Simon, R	1
Kochi, K	1
Kyo, S	2
Yokote, Y	2
Ueda, K	1
Asano, H	2
Koyanagi, T	2
Ohuchi, H	1
Omoto, R	2
Gillard, P	1
Laurent, M	1
Ouchi, H	1
Lehot, JJ	1
Klocke, RK	1
Mager, G	1
Kux, A	1
Höpp, HW	1
Hilger, HH	1