Page last updated: 2024-10-31

milrinone and Right Ventricular Dysfunction

milrinone has been researched along with Right Ventricular Dysfunction in 25 studies

Research Excerpts

ExcerptRelevanceReference
" The aim of this study was to investigate the postoperative hemodynamic effects of milrinone inhalation, and determine whether it has a selective effect of pulmonary vasodilation in patients with pulmonary hypertension undergoing mitral valve replacement surgery."9.14Comparison of inhaled and intravenous milrinone in patients with pulmonary hypertension undergoing mitral valve surgery. ( Dai, A; Gong, M; Wang, H; Zhou, B, 2009)
"Milrinone has been proposed as an effective treatment for pulmonary hypertension (PH) and right ventricular (RV) dysfunction."7.81Treatment of premature infants with pulmonary hypertension and right ventricular dysfunction with milrinone: a case series. ( Bee, C; Corcoran, JD; El-Khuffash, AF; Franklin, O; James, AT; McNamara, PJ, 2015)
"In the setting of monocrotaline pyrrole-induced recipient pulmonary hypertension, milrinone was associated with significant improvements in pulmonary vascular impedance, right ventricular function, and transpulmonary efficiency."7.70Hemodynamic and inotropic effects of milrinone after heart transplantation in the setting of recipient pulmonary hypertension. ( Bittner, HB; Chen, EP; Davis, RD; Van Trigt, P, 1998)
"Milrinone use was associated with an improvement in systolic and diastolic function in the RV, corresponding to an improvement in clinical status."5.38Use of milrinone to treat cardiac dysfunction in infants with pulmonary hypertension secondary to congenital diaphragmatic hernia: a review of six patients. ( Patel, N, 2012)
" The aim of this study was to investigate the postoperative hemodynamic effects of milrinone inhalation, and determine whether it has a selective effect of pulmonary vasodilation in patients with pulmonary hypertension undergoing mitral valve replacement surgery."5.14Comparison of inhaled and intravenous milrinone in patients with pulmonary hypertension undergoing mitral valve surgery. ( Dai, A; Gong, M; Wang, H; Zhou, B, 2009)
"Milrinone has been proposed as an effective treatment for pulmonary hypertension (PH) and right ventricular (RV) dysfunction."3.81Treatment of premature infants with pulmonary hypertension and right ventricular dysfunction with milrinone: a case series. ( Bee, C; Corcoran, JD; El-Khuffash, AF; Franklin, O; James, AT; McNamara, PJ, 2015)
"In the setting of monocrotaline pyrrole-induced recipient pulmonary hypertension, milrinone was associated with significant improvements in pulmonary vascular impedance, right ventricular function, and transpulmonary efficiency."3.70Hemodynamic and inotropic effects of milrinone after heart transplantation in the setting of recipient pulmonary hypertension. ( Bittner, HB; Chen, EP; Davis, RD; Van Trigt, P, 1998)
"This study was designed to examine the effects of both nitric oxide and milrinone on pulmonary hemodynamics and right ventricular function using a newly established model of monocrotaline pyrrole-induced chronic pulmonary hypertension."3.69Right ventricular failure--insights provided by a new model of chronic pulmonary hypertension. ( Bittner, HB; Chen, EP; Davis, RD; Van Trigt, P, 1997)
"Iloprost was administered during weaning from cardiopulmonary bypass (CPB)."2.73Inhaled iloprost to control pulmonary artery hypertension in patients undergoing mitral valve surgery: a prospective, randomized-controlled trial. ( Autschbach, R; Buhre, W; de Waal, EE; Flier, S; Metzelder, S; Rex, S; Rossaint, R; Schaelte, G, 2008)
"Dobutamine-treated animals had lower perfusion pressures and blood pH compared with epinephrine + milrinone and dopamine + milrinone groups."1.40Inotropic therapy for right ventricular failure in newborn piglets: effect on contractility, hemodynamics, and interventricular interaction. ( Frederiksen, CA; Heiberg, J; Hyldebrandt, JA; Ravn, HB; Redington, AN; Rothmann, S; Schmidt, MR, 2014)
"Milrinone use was associated with an improvement in systolic and diastolic function in the RV, corresponding to an improvement in clinical status."1.38Use of milrinone to treat cardiac dysfunction in infants with pulmonary hypertension secondary to congenital diaphragmatic hernia: a review of six patients. ( Patel, N, 2012)
"Severe pulmonary thromboembolism has been occasionally reported during orthotopic liver transplantation, with fatal outcomes occurring in about 50% of cases because of low cardiac output and multiple organ failure."1.33Cardiovascular collapse due to massive pulmonary thromboembolism during orthotopic liver transplantation. ( Ellenberger, C; Giostra, E; Licker, M; Mentha, G, 2006)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (8.00)18.2507
2000's7 (28.00)29.6817
2010's11 (44.00)24.3611
2020's5 (20.00)2.80

Authors

AuthorsStudies
Elmi-Sarabi, M4
Couture, E2
Jarry, S3
Saade, E2
Calderone, A3
Potes, C2
Denault, A3
Sia, YT1
Gebhard, CE3
Denault, AY4
Coleman, RD1
Chartan, CA1
Mourani, PM1
Uriel, N1
Burkhoff, D1
Kim, G1
Silverstein, T1
Juricek, C1
Kaye, DM1
Sayer, G1
Hammoud, A1
Couture, EJ3
Sabato, LA1
Salerno, DM1
Moretz, JD1
Jennings, DL1
Tremblay, JA1
Lamarche, Y1
Heringlake, M1
Berggreen, AE1
Rochon, A1
Cogan, J1
Ased, H1
Desjardins, G2
Deschamps, A1
Gavra, P2
Lebon, JS1
Couture, P1
Ayoub, C1
Levesque, S1
Hyldebrandt, JA2
Frederiksen, CA2
Heiberg, J2
Rothmann, S1
Redington, AN1
Schmidt, MR1
Ravn, HB2
James, AT1
Bee, C1
Corcoran, JD1
McNamara, PJ1
Franklin, O1
El-Khuffash, AF1
Haglund, NA1
Burdorf, A1
Jones, T1
Shostrom, V1
Um, J1
Ryan, T1
Shillcutt, S1
Fischer, P1
Cox, ZL1
Raichlin, E1
Anderson, DR1
Lowes, BD1
Dumitru, I1
Sivén, E1
Agger, P1
Wemmelund, KB1
Gebhard, C1
Patel, ND1
Weiss, ES1
Schaffer, J1
Ullrich, SL1
Rivard, DC1
Shah, AS1
Russell, SD1
Conte, JV1
Wang, H1
Gong, M1
Zhou, B1
Dai, A1
Patel, N1
Giaccone, A1
Kirpalani, H1
Ellenberger, C1
Mentha, G1
Giostra, E1
Licker, M1
Rex, S1
Schaelte, G1
Metzelder, S1
Flier, S1
de Waal, EE1
Autschbach, R1
Rossaint, R1
Buhre, W1
Chen, EP2
Bittner, HB2
Davis, RD2
Van Trigt, P2
Stobierska-Dzierzek, B1
Awad, H1
Michler, RE1
Ricksten, S1
Kihara, S1
Kawai, A1
Fukuda, T1
Yamamoto, N1
Aomi, S1
Nishida, H1
Endo, M1
Koyanagi, H1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Validation of Cerebral Non-invasive Monitoring and Prediction of Post-operative Delirium and Outcomes: A Prospective Observational Study[NCT04643834]151 participants (Anticipated)Observational2019-11-21Recruiting
Comparative Study Between Inhaled and Intravenous Milrinone in Patients With Severe Pulmonary Hypertension Undergoing Cardiac Surgery[NCT04484675]Phase 438 participants (Anticipated)Interventional2022-01-20Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for milrinone and Right Ventricular Dysfunction

ArticleYear
Intensive care management of right ventricular failure and pulmonary hypertension crises.
    Pediatric pulmonology, 2021, Volume: 56, Issue:3

    Topics: Biomarkers; Capnography; Central Venous Pressure; Critical Care; Echocardiography; Epinephrine; Epop

2021
Inhaled Pulmonary Vasodilator Therapy for Management of Right Ventricular Dysfunction after Left Ventricular Assist Device Placement and Cardiac Transplantation.
    Pharmacotherapy, 2017, Volume: 37, Issue:8

    Topics: Administration, Inhalation; Heart Transplantation; Heart-Assist Devices; Humans; Iloprost; Milrinone

2017
The evolving management of acute right-sided heart failure in cardiac transplant recipients.
    Journal of the American College of Cardiology, 2001, Volume: 38, Issue:4

    Topics: Alprostadil; Animals; Cardiotonic Agents; Epoprostenol; Heart Transplantation; Heart-Assist Devices;

2001
[The pulmonary vasodilatory effect of inhaled prostacyclin and milrinone in heart].
    Revista espanola de anestesiologia y reanimacion, 2001, Volume: 48, Issue:10

    Topics: Acute Disease; Administration, Inhalation; Cardiac Surgical Procedures; Cyclic AMP; Drug Synergism;

2001

Trials

3 trials available for milrinone and Right Ventricular Dysfunction

ArticleYear
Inhaled Milrinone After Left Ventricular Assist Device Implantation.
    Journal of cardiac failure, 2015, Volume: 21, Issue:10

    Topics: Administration, Inhalation; Aged; Cost-Benefit Analysis; Female; Heart Failure; Heart Ventricles; He

2015
Comparison of inhaled and intravenous milrinone in patients with pulmonary hypertension undergoing mitral valve surgery.
    Advances in therapy, 2009, Volume: 26, Issue:4

    Topics: Administration, Inhalation; Adult; Analysis of Variance; Cardiac Output; Cardiopulmonary Bypass; Fem

2009
Inhaled iloprost to control pulmonary artery hypertension in patients undergoing mitral valve surgery: a prospective, randomized-controlled trial.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:1

    Topics: Administration, Inhalation; Aged; Cardiac Output, Low; Cardiopulmonary Bypass; Catheterization, Swan

2008

Other Studies

18 other studies available for milrinone and Right Ventricular Dysfunction

ArticleYear
Inhaled Epoprostenol and Milrinone Effect on Right Ventricular Pressure Waveform Monitoring.
    The Canadian journal of cardiology, 2023, Volume: 39, Issue:4

    Topics: Adult; Cohort Studies; Epoprostenol; Humans; Hypertension, Pulmonary; Milrinone; Prospective Studies

2023
Inhaled Epoprostenol and Milrinone Effect on Right Ventricular Pressure Waveform Monitoring.
    The Canadian journal of cardiology, 2023, Volume: 39, Issue:4

    Topics: Adult; Cohort Studies; Epoprostenol; Humans; Hypertension, Pulmonary; Milrinone; Prospective Studies

2023
Inhaled Epoprostenol and Milrinone Effect on Right Ventricular Pressure Waveform Monitoring.
    The Canadian journal of cardiology, 2023, Volume: 39, Issue:4

    Topics: Adult; Cohort Studies; Epoprostenol; Humans; Hypertension, Pulmonary; Milrinone; Prospective Studies

2023
Inhaled Epoprostenol and Milrinone Effect on Right Ventricular Pressure Waveform Monitoring.
    The Canadian journal of cardiology, 2023, Volume: 39, Issue:4

    Topics: Adult; Cohort Studies; Epoprostenol; Humans; Hypertension, Pulmonary; Milrinone; Prospective Studies

2023
Reversal of Acute Right Ventricular Failure Early Post Left Ventricular Assist Device Placement by Intratracheal Milrinone Administration: Case Report.
    Chest, 2021, Volume: 159, Issue:1

    Topics: Cardiotonic Agents; Echocardiography, Transesophageal; Heart Failure; Heart-Assist Devices; Humans;

2021
Oral Milrinone for the Treatment of Chronic Severe Right Ventricular Failure in Left Ventricular Assist Device Patients.
    Circulation. Heart failure, 2021, Volume: 14, Issue:4

    Topics: Administration, Oral; Cardiotonic Agents; Combined Modality Therapy; Female; Heart-Assist Devices; H

2021
Femoral Vein Pulsatility: What Does It Mean?
    Journal of cardiothoracic and vascular anesthesia, 2021, Volume: 35, Issue:8

    Topics: Aged; Cardiac Surgical Procedures; Femoral Vein; Humans; Milrinone; Portal Vein; Pulsatile Flow; Ven

2021
Noninvasive Administration of Inhaled Epoprostenol and Inhaled Milrinone in Extubated, Spontaneously Breathing Patients With Right Ventricular Failure and Portal Hypertension: A Report of 2 Cases.
    A&A practice, 2019, Mar-15, Volume: 12, Issue:6

    Topics: Administration, Inhalation; Aged; Airway Extubation; Antihypertensive Agents; Cardiac Surgical Proce

2019
Intratracheal Milrinone for Acute Right Heart Dysfunction: Another Tool in the Pocket.
    Journal of cardiothoracic and vascular anesthesia, 2019, Volume: 33, Issue:3

    Topics: Cardiopulmonary Bypass; Heart Failure; Humans; Milrinone; Retrospective Studies; Ventricular Dysfunc

2019
Acute Right Ventricular Failure in Cardiac Surgery During Cardiopulmonary Bypass Separation: A Retrospective Case Series of 12 Years' Experience With Intratracheal Milrinone Administration.
    Journal of cardiothoracic and vascular anesthesia, 2019, Volume: 33, Issue:3

    Topics: Acute Disease; Aged; Cardiopulmonary Bypass; Cardiotonic Agents; Echocardiography, Transesophageal;

2019
Inotropic therapy for right ventricular failure in newborn piglets: effect on contractility, hemodynamics, and interventricular interaction.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2014, Volume: 15, Issue:7

    Topics: Animals; Animals, Newborn; Blood Pressure; Cardiotonic Agents; Disease Models, Animal; Dobutamine; D

2014
Treatment of premature infants with pulmonary hypertension and right ventricular dysfunction with milrinone: a case series.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:4

    Topics: Blood Pressure; Echocardiography; Female; Fetofetal Transfusion; Humans; Hypertension, Pulmonary; In

2015
Effects of milrinone and epinephrine or dopamine on biventricular function and hemodynamics in an animal model with right ventricular failure after pulmonary artery banding.
    American journal of physiology. Heart and circulatory physiology, 2015, Jul-01, Volume: 309, Issue:1

    Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Dopamine; Epinephrine; Heart Failure; Heart Ven

2015
Intratracheal Milrinone Bolus Administration During Acute Right Ventricular Dysfunction After Cardiopulmonary Bypass.
    Journal of cardiothoracic and vascular anesthesia, 2017, Volume: 31, Issue:2

    Topics: Aged; Cardiopulmonary Bypass; Cardiotonic Agents; Cohort Studies; Female; Humans; Intubation, Intrat

2017
Right heart dysfunction after left ventricular assist device implantation: a comparison of the pulsatile HeartMate I and axial-flow HeartMate II devices.
    The Annals of thoracic surgery, 2008, Volume: 86, Issue:3

    Topics: Blood Pressure; Epinephrine; Female; Heart-Assist Devices; Hemodynamics; Humans; Length of Stay; Mal

2008
Use of milrinone to treat cardiac dysfunction in infants with pulmonary hypertension secondary to congenital diaphragmatic hernia: a review of six patients.
    Neonatology, 2012, Volume: 102, Issue:2

    Topics: Antihypertensive Agents; Arterial Pressure; Cardiotonic Agents; Diastole; Echocardiography, Doppler;

2012
Judgment often impossible without randomized trials. Commentary on N. Patel: use of milrinone to treat cardiac dysfunction in infants with pulmonary hypertension secondary to congenital diaphragmatic hernia: a review of six patients (Neonatology 2012;102:
    Neonatology, 2012, Volume: 102, Issue:2

    Topics: Antihypertensive Agents; Cardiotonic Agents; Familial Primary Pulmonary Hypertension; Female; Hernia

2012
Cardiovascular collapse due to massive pulmonary thromboembolism during orthotopic liver transplantation.
    Journal of clinical anesthesia, 2006, Volume: 18, Issue:5

    Topics: Aprotinin; Blood Pressure; Bronchodilator Agents; Cardiotonic Agents; Catheterization, Swan-Ganz; Ec

2006
Right ventricular failure--insights provided by a new model of chronic pulmonary hypertension.
    Transplantation, 1997, Jan-27, Volume: 63, Issue:2

    Topics: Administration, Inhalation; Animals; Blood Pressure; Cardiac Output; Dogs; Heart Rate; Hemodynamics;

1997
Hemodynamic and inotropic effects of milrinone after heart transplantation in the setting of recipient pulmonary hypertension.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 1998, Volume: 17, Issue:7

    Topics: Animals; Dogs; Heart Transplantation; Hemodynamics; Hypertension, Pulmonary; Milrinone; Monocrotalin

1998
Effects of milrinone for right ventricular failure after left ventricular assist device implantation.
    Heart and vessels, 2002, Volume: 16, Issue:2

    Topics: Adolescent; Cardiotonic Agents; Heart Failure; Humans; Male; Middle Aged; Milrinone; Pacemaker, Arti

2002