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milrinone and Patency of the Ductus Arteriosus

milrinone has been researched along with Patency of the Ductus Arteriosus in 13 studies

Research Excerpts

ExcerptRelevanceReference
"Population pharmacokinetic modeling and simulations suggest a slow loading dose followed by maintenance infusion to reach therapeutic milrinone plasma concentrations within the timeframe of the postligation cardiac syndrome."3.91Population Pharmacokinetics and Dosing of Milrinone After Patent Ductus Arteriosus Ligation in Preterm Infants. ( Hallik, M; Ilmoja, ML; Jalas, T; Kipper, K; Metsvaht, T; Raidmäe, M; Standing, JF; Starkopf, J; Takkis, K; Tasa, T; Uibo, K; Veigure, R, 2019)
" The differential effects of these PDE 3 inhibitors on the near-term and preterm ductus were studied by injecting indomethacin (10 mg/kg) and PDE 3 inhibitors into 21D (21st day of pregnancy: term-21."3.73In vivo dilatation of the fetal and postnatal ductus arteriosus by inhibition of phosphodiesterase 3 in rats. ( Imamura, S; Momma, K; Nakanishi, T; Toyoshima, K, 2006)
"Milrinone is administered after patent ductus arteriosus (PDA) ligation to prevent and treat postoperative hemodynamic instability (i."1.91Effects of Milrinone on Neonates after Patent Ductus Arteriosus Ligation: A Retrospective Nationwide Database Study. ( Fujita, A; Ito, A; Kashima, K; Kato, M; Kitaoka, H; Konishi, T; Matsui, H; Shitara, Y; Takahashi, N; Yasunaga, H, 2023)
"Milrinone was initiated if LVO was < 200 mL/kg/min 1 h after surgery, to prevent PLCS."1.72Lung ultrasound score parallels trends in systemic haemodynamics after PDA ligation: a case series. ( Cattarossi, L; McNamara, PJ; Savoia, M; Titolo, A, 2022)
"Milrinone has been suggested as a possible first-line therapy for preterm neonates to prevent postligation cardiac syndrome (PLCS) through decreasing systemic vascular resistance and increasing cardiac contractility."1.46Dosing of Milrinone in Preterm Neonates to Prevent Postligation Cardiac Syndrome: Simulation Study Suggests Need for Bolus Infusion. ( Hallik, M; Metsvaht, T; Starkopf, J; Tasa, T, 2017)
"Hypotension is a common problem in neonates with complex underlying pathophysiology."1.46Management of Neonatal Hypotension. ( Kalish, BT, 2017)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (23.08)29.6817
2010's8 (61.54)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Savoia, M1
McNamara, PJ4
Titolo, A1
Cattarossi, L1
Kitaoka, H1
Konishi, T1
Shitara, Y1
Ito, A1
Kashima, K1
Fujita, A1
Matsui, H1
Kato, M1
Takahashi, N1
Yasunaga, H1
Hallik, M2
Ilmoja, ML1
Tasa, T2
Standing, JF1
Takkis, K1
Veigure, R1
Kipper, K1
Jalas, T1
Raidmäe, M1
Uibo, K1
Starkopf, J2
Metsvaht, T2
EL-Khuffash, A2
Lapointe, A1
Jain, A3
El-Khuffash, AF1
Weisz, D1
Mertens, L1
Halliday, M1
Kavarana, M1
Ebeling, M1
Kiger, J1
Ting, JY1
Resende, M1
More, K1
Nicholls, D1
Weisz, DE1
Kalish, BT1
Sehgal, A1
Francis, JV1
Lewis, AI1
Seri, I1
Noori, S1
Osborn, DA1
Toyoshima, K1
Momma, K1
Imamura, S1
Nakanishi, T1

Reviews

2 reviews available for milrinone and Patency of the Ductus Arteriosus

ArticleYear
Diagnosis and treatment of neonatal hypotension outside the transitional period.
    Early human development, 2005, Volume: 81, Issue:5

    Topics: Adrenal Insufficiency; Dobutamine; Dopamine; Ductus Arteriosus, Patent; Humans; Hypotension; Infant,

2005
Diagnosis and treatment of preterm transitional circulatory compromise.
    Early human development, 2005, Volume: 81, Issue:5

    Topics: Adrenal Cortex Hormones; Blood Circulation; Blood Pressure; Cardiac Output, Low; Dobutamine; Dopamin

2005

Other Studies

11 other studies available for milrinone and Patency of the Ductus Arteriosus

ArticleYear
Lung ultrasound score parallels trends in systemic haemodynamics after PDA ligation: a case series.
    European journal of pediatrics, 2022, Volume: 181, Issue:6

    Topics: Adult; Birth Weight; Ductus Arteriosus, Patent; Hemodynamics; Humans; Infant; Infant, Newborn; Infan

2022
Effects of Milrinone on Neonates after Patent Ductus Arteriosus Ligation: A Retrospective Nationwide Database Study.
    Neonatology, 2023, Volume: 120, Issue:6

    Topics: Bronchopulmonary Dysplasia; Cerebral Hemorrhage; Ductus Arteriosus, Patent; Enterocolitis, Necrotizi

2023
Population Pharmacokinetics and Dosing of Milrinone After Patent Ductus Arteriosus Ligation in Preterm Infants.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2019, Volume: 20, Issue:7

    Topics: Cardiotonic Agents; Ductus Arteriosus, Patent; Echocardiography; Female; Humans; Hypotension; Infant

2019
Adrenal function in preterm infants undergoing patent ductus arteriosus ligation.
    Neonatology, 2013, Volume: 104, Issue:1

    Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Cardiotonic Agents; Cohort Studies; Ductus Arter

2013
Assessment and treatment of post patent ductus arteriosus ligation syndrome.
    The Journal of pediatrics, 2014, Volume: 165, Issue:1

    Topics: Cardiac Output; Cardiotonic Agents; Ductus Arteriosus, Patent; Echocardiography, Doppler; Elasticity

2014
Milrinone use for hemodynamic instability in patent ductus arteriosus ligation.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2017, Volume: 30, Issue:5

    Topics: Birth Weight; Chi-Square Distribution; Ductus Arteriosus, Patent; Gestational Age; Hemodynamics; Hum

2017
Predictors of respiratory instability in neonates undergoing patient ductus arteriosus ligation after the introduction of targeted milrinone treatment.
    The Journal of thoracic and cardiovascular surgery, 2016, Volume: 152, Issue:2

    Topics: Cardiac Surgical Procedures; Chi-Square Distribution; Ductus Arteriosus, Patent; Echocardiography, D

2016
Dosing of Milrinone in Preterm Neonates to Prevent Postligation Cardiac Syndrome: Simulation Study Suggests Need for Bolus Infusion.
    Neonatology, 2017, Volume: 111, Issue:1

    Topics: Cardiac Output; Cardiotonic Agents; Ductus Arteriosus, Patent; Estonia; Female; Gestational Age; Hum

2017
Management of Neonatal Hypotension.
    Neonatal network : NN, 2017, Jan-01, Volume: 36, Issue:1

    Topics: Blood Pressure; Cardiotonic Agents; Dobutamine; Dopamine; Ductus Arteriosus, Patent; Humans; Hypoten

2017
Use of milrinone in the management of haemodynamic instability following duct ligation.
    European journal of pediatrics, 2011, Volume: 170, Issue:1

    Topics: Blood Pressure; Ductus Arteriosus, Patent; Heart; Hemodynamics; Humans; Infant, Newborn; Male; Milri

2011
In vivo dilatation of the fetal and postnatal ductus arteriosus by inhibition of phosphodiesterase 3 in rats.
    Biology of the neonate, 2006, Volume: 89, Issue:4

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Animals, Newborn; Cyclic Nucleotide Phosphodiesterases

2006