milrinone has been researched along with Left Ventricular Dysfunction in 31 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the effects of levosimendan with milrinone in cardiac surgical patients with pulmonary hypertension and left ventricular dysfunction." | 9.22 | Comparative Effect of Levosimendan and Milrinone in Cardiac Surgery Patients With Pulmonary Hypertension and Left Ventricular Dysfunction. ( Arya, VK; Dutta, V; Kumar, B; Mishra, A; Mishra, AK, 2016) |
| "The purpose of this study was to determine whether a low-dose β-blocker, in combination with milrinone, improves cardiac function in acute decompensated heart failure (ADHF) with tachycardia." | 7.78 | Low-dose β-blocker in combination with milrinone safely improves cardiac function and eliminates pulsus alternans in patients with acute decompensated heart failure. ( Doi, M; Fukuta, S; Kobayashi, S; Matsuzaki, M; Murakami, W; Nao, T; Okamura, T; Okuda, S; Susa, T; Tanaka, T; Wada, Y; Yamada, J; Yano, M, 2012) |
| "Bolus milrinone consistently decreases PVR in patients with pulmonary hypertension secondary to severe heart failure." | 7.69 | Effect of bolus milrinone on hemodynamic variables and pulmonary vascular resistance in patients with severe left ventricular dysfunction: a rapid test for reversibility of pulmonary hypertension. ( Colucci, WS; Gauthier, DF; Givertz, MM; Hare, JM; Loh, E, 1996) |
| "esmolol was infused to decrease baseline heart rate (HR) by approximately 25%, and all animals received an esmolol infusion (150 microg kg(-1) min(-1))." | 5.33 | Treatment of ischaemic left ventricular dysfunction with milrinone or dobutamine administered during coronary artery stenosis in the presence of beta blockade in pigs. ( Kirby, DS; Lobato, EB; Muehlschlegel, JD; Sidi, A, 2006) |
| "To compare the effects of levosimendan with milrinone in cardiac surgical patients with pulmonary hypertension and left ventricular dysfunction." | 5.22 | Comparative Effect of Levosimendan and Milrinone in Cardiac Surgery Patients With Pulmonary Hypertension and Left Ventricular Dysfunction. ( Arya, VK; Dutta, V; Kumar, B; Mishra, A; Mishra, AK, 2016) |
| "Serum levels of creatine phosphokinase (CPK), the MB isoenzyme of creatine kinase (CK-MB), occurrence of myocardial ischemia or infarction, and mean duration of using inotropic agents were significantly lower in the milrinone group (p < 0." | 5.14 | Effect of milrinone on short-term outcome of patients with myocardial dysfunction undergoing coronary artery bypass graft: A randomized controlled trial. ( Darehzereshki, A; Dianat, S; Eghtesadi-Araghi, P; Ghazinoor, M; Goodarzynejad, H; Jebeli, M; Mandegar, MH; Mohammadzadeh, R; Rasouli, MR, 2010) |
| "A four- and a half-month-old girl with severe dilated cardiomyopathy due to neonatal enterovirus myocarditis, treated with diuretics and milrinone for the past 4 months, was infected with SARS-CoV-2." | 4.02 | SARS-CoV-2 infection in an infant with severe dilated cardiomyopathy. ( Knudsen, PK; Kristoffersen, AW; Møller, T, 2021) |
| "The purpose of this study was to determine whether a low-dose β-blocker, in combination with milrinone, improves cardiac function in acute decompensated heart failure (ADHF) with tachycardia." | 3.78 | Low-dose β-blocker in combination with milrinone safely improves cardiac function and eliminates pulsus alternans in patients with acute decompensated heart failure. ( Doi, M; Fukuta, S; Kobayashi, S; Matsuzaki, M; Murakami, W; Nao, T; Okamura, T; Okuda, S; Susa, T; Tanaka, T; Wada, Y; Yamada, J; Yano, M, 2012) |
| "To evaluate: 1) the effects of dobutamine (DOB) on left ventricular function in early (48-72 h) and late (14 days) phases of a post-MI canine model, compared to ISTA, and 2) the efficacy of DOB in chronic left ventricular dysfunction (6 months post-MI) in dogs pre-treated or not with a beta-blocker, compared with ISTA and milrinone (MIL)." | 3.74 | Sympathomimetic inefficiency in restoring contractility in the acute or chronic beta-blocker-treated ischaemic heart: comparison with a new agent. ( Borsini, F; Carminati, P; Gagnol, JP; Loi, FM; Mattera, GG; Vanoli, E, 2008) |
| "Bolus milrinone consistently decreases PVR in patients with pulmonary hypertension secondary to severe heart failure." | 3.69 | Effect of bolus milrinone on hemodynamic variables and pulmonary vascular resistance in patients with severe left ventricular dysfunction: a rapid test for reversibility of pulmonary hypertension. ( Colucci, WS; Gauthier, DF; Givertz, MM; Hare, JM; Loh, E, 1996) |
| "Levosimendan is a new calcium sensitizer with inodilatory properties." | 2.71 | Levosimendan in cardiac surgery. ( Harjola, VP; Siirilä-Waris, K; Suojaranta-Ylinen, R, 2005) |
| "Myocarditis is a common cause for acute heart failure in the pediatric population." | 1.51 | Does myocardial strain remain abnormal long after normalization of ejection fraction in patients with acute myocarditis? ( Bourget, L; Garg, A; Manalo, R; Swaminathan, S, 2019) |
| "The echocardiographic presence of mild aortic regurgitation combined with left ventricular hypocontractility in a structurally normal heart should alert the physician to the presence of underlying hypertension." | 1.39 | Neonatal circulatory failure due to acute hypertensive crisis: clinical and echocardiographic clues. ( Allegaert, K; Brown, S; Cools, B; Eyskens, B; Gewillig, M; Heying, R; Levtchenko, E; Louw, J; Smits, A; Thewissen, L, 2013) |
| "Transcatheter closure of atrial septal defects (ASDs) is a safe and effective treatment." | 1.33 | Left ventricular conditioning in the elderly patient to prevent congestive heart failure after transcatheter closure of atrial septal defect. ( Abdul-Khaliq, H; Ewert, P; Lange, PE; Nagdyman, N; Peters, B; Schubert, S, 2005) |
| "esmolol was infused to decrease baseline heart rate (HR) by approximately 25%, and all animals received an esmolol infusion (150 microg kg(-1) min(-1))." | 1.33 | Treatment of ischaemic left ventricular dysfunction with milrinone or dobutamine administered during coronary artery stenosis in the presence of beta blockade in pigs. ( Kirby, DS; Lobato, EB; Muehlschlegel, JD; Sidi, A, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (9.68) | 18.2507 |
| 2000's | 15 (48.39) | 29.6817 |
| 2010's | 11 (35.48) | 24.3611 |
| 2020's | 2 (6.45) | 2.80 |
| Authors | Studies |
|---|---|
| Cottenceau, V | 1 |
| Poutier, B | 1 |
| Gariel, F | 1 |
| Sauvage, N | 1 |
| Petit, L | 1 |
| Carrie, C | 1 |
| Biais, M | 1 |
| Kristoffersen, AW | 1 |
| Knudsen, PK | 1 |
| Møller, T | 1 |
| Manalo, R | 1 |
| Bourget, L | 1 |
| Garg, A | 1 |
| Swaminathan, S | 1 |
| Mears, M | 1 |
| Yang, M | 1 |
| Yoder, BA | 1 |
| EL-Khuffash, A | 1 |
| McNamara, PJ | 1 |
| Lapointe, A | 1 |
| Jain, A | 1 |
| Louw, J | 1 |
| Brown, S | 1 |
| Thewissen, L | 1 |
| Smits, A | 1 |
| Eyskens, B | 1 |
| Heying, R | 1 |
| Cools, B | 1 |
| Levtchenko, E | 1 |
| Allegaert, K | 1 |
| Gewillig, M | 1 |
| Adatya, S | 1 |
| Adataya, S | 1 |
| Masri, C | 1 |
| John, R | 1 |
| Eckman, P | 1 |
| Axelsson, B | 1 |
| Häggmark, S | 1 |
| Svenmarker, S | 1 |
| Johansson, G | 1 |
| Gupta, A | 1 |
| Tydén, H | 1 |
| Wouters, P | 1 |
| Haney, M | 1 |
| Mishra, A | 1 |
| Kumar, B | 1 |
| Dutta, V | 1 |
| Arya, VK | 1 |
| Mishra, AK | 1 |
| Furck, AK | 1 |
| Bentley, S | 1 |
| Bartsota, M | 1 |
| Rigby, ML | 1 |
| Slavik, Z | 1 |
| Mattera, GG | 1 |
| Vanoli, E | 1 |
| Gagnol, JP | 1 |
| Loi, FM | 1 |
| Borsini, F | 1 |
| Carminati, P | 1 |
| Yamaguchi, A | 1 |
| Tanaka, M | 1 |
| Naito, K | 1 |
| Kimura, C | 1 |
| Kobinata, T | 1 |
| Okamura, H | 1 |
| Ino, T | 1 |
| Adachi, H | 1 |
| Jebeli, M | 1 |
| Ghazinoor, M | 1 |
| Mandegar, MH | 1 |
| Rasouli, MR | 1 |
| Eghtesadi-Araghi, P | 1 |
| Goodarzynejad, H | 1 |
| Mohammadzadeh, R | 1 |
| Darehzereshki, A | 1 |
| Dianat, S | 1 |
| Kobayashi, S | 1 |
| Susa, T | 1 |
| Tanaka, T | 1 |
| Murakami, W | 1 |
| Fukuta, S | 1 |
| Okuda, S | 1 |
| Doi, M | 1 |
| Wada, Y | 1 |
| Nao, T | 1 |
| Yamada, J | 1 |
| Okamura, T | 1 |
| Yano, M | 1 |
| Matsuzaki, M | 1 |
| Yasumura, Y | 1 |
| Möllhoff, T | 1 |
| Schmidt, C | 1 |
| Van Aken, H | 1 |
| Berendes, E | 1 |
| Buerkle, H | 1 |
| Marmann, P | 1 |
| Reinbold, T | 1 |
| Prenger-Berninghoff, R | 1 |
| Tjan, TD | 1 |
| Scheld, HH | 1 |
| Deng, MC | 1 |
| Gheorghiade, M | 1 |
| Gattis, WA | 1 |
| Klein, L | 1 |
| Niemann, JT | 1 |
| Garner, D | 1 |
| Khaleeli, E | 1 |
| Lewis, RJ | 1 |
| De Luca, L | 1 |
| Proietti, P | 1 |
| Palombaro, GL | 1 |
| Battagliese, A | 1 |
| Celotto, A | 1 |
| Bucciarelli Ducci, C | 1 |
| Fedele, F | 1 |
| Schubert, S | 1 |
| Peters, B | 1 |
| Abdul-Khaliq, H | 1 |
| Nagdyman, N | 1 |
| Lange, PE | 1 |
| Ewert, P | 1 |
| Albrecht, CA | 1 |
| Giesler, GM | 1 |
| Kar, B | 1 |
| Hariharan, R | 1 |
| Delgado, RM | 1 |
| Siirilä-Waris, K | 1 |
| Suojaranta-Ylinen, R | 1 |
| Harjola, VP | 1 |
| Sidi, A | 2 |
| Muehlschlegel, JD | 2 |
| Kirby, DS | 2 |
| Lobato, EB | 3 |
| Pagel, PS | 1 |
| Simkova, V | 1 |
| Radermacher, P | 1 |
| Barth, E | 1 |
| Herweg, B | 1 |
| Ilercil, A | 1 |
| Cutro, R | 1 |
| Dewhurst, R | 1 |
| Krishnan, S | 1 |
| Weston, M | 1 |
| Barold, SS | 1 |
| Givertz, MM | 1 |
| Hare, JM | 1 |
| Loh, E | 1 |
| Gauthier, DF | 1 |
| Colucci, WS | 1 |
| Florete, O | 1 |
| Bingham, HL | 1 |
| Mills, RM | 1 |
| Cunningham, MS | 1 |
| Dhar, SC | 1 |
| Birnbaum, Y | 1 |
| Hayes, S | 1 |
| Naqvi, T | 1 |
| Cercek, B | 1 |
| Blanche, C | 1 |
| Friedman, A | 1 |
| Trento, A | 1 |
| Siegel, RJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| 2- Inhaled Milrinone Prevents the Increase in Pulmonary Artery Pressure After CPB[NCT00819377] | Phase 2 | 124 participants (Anticipated) | Interventional | 2009-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for milrinone and Left Ventricular Dysfunction
| Article | Year |
|---|---|
New positive inotropic agents in the treatment of left ventricular dysfunction.
Topics: Cardiotonic Agents; Diastole; Heart Failure; Humans; Hydrazones; Milrinone; Myocardial Ischemia; Pho | 2004 |
8 trials available for milrinone and Left Ventricular Dysfunction
| Article | Year |
|---|---|
Comparative Effect of Levosimendan and Milrinone in Cardiac Surgery Patients With Pulmonary Hypertension and Left Ventricular Dysfunction.
Topics: Adult; Aortic Valve; Arterial Pressure; Drug Administration Schedule; Drug Therapy, Combination; Fem | 2016 |
Effect of milrinone on short-term outcome of patients with myocardial dysfunction undergoing coronary artery bypass graft: A randomized controlled trial.
Topics: Aged; Cardiotonic Agents; Coronary Artery Bypass; Creatine Kinase; Creatine Kinase, MB Form; Drug Ad | 2010 |
Myocardial ischaemia in patients with impaired left ventricular function undergoing coronary artery bypass grafting--milrinone versus nifedipin.
Topics: Aged; Anesthesia, General; Calcium Channel Blockers; Coronary Artery Bypass; Coronary Disease; Creat | 2002 |
OPTIME in CHF trial: rethinking the use of inotropes in the management of worsening chronic heart failure resulting in hospitalization.
Topics: Cardiotonic Agents; Chronic Disease; Heart Failure; Humans; Infusions, Intravenous; Milrinone; Patie | 2003 |
Levosimendan in cardiac surgery.
Topics: Aged; Anti-Arrhythmia Agents; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Coronary Artery D | 2005 |
Cardiac resynchronization therapy in patients with end-stage inotrope-dependent class IV heart failure.
Topics: Adult; Aged; Cardiac Pacing, Artificial; Cardiotonic Agents; Defibrillators, Implantable; Dobutamine | 2007 |
A single dose of milrinone facilitates separation from cardiopulmonary bypass in patients with pre-existing left ventricular dysfunction.
Topics: Adult; Cardiopulmonary Bypass; Cardiotonic Agents; Coronary Artery Bypass; Drug Administration Sched | 1998 |
Milrinone echocardiographic viability test: a pilot study.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aged; Coronary Artery Bypass; Cyclic Nucleotide Phosphodiestera | 2001 |
22 other studies available for milrinone and Left Ventricular Dysfunction
| Article | Year |
|---|---|
May levosimendan be safe and effective in refractory vasospasm despite adequate treatment with repeated angiography and milrinone infusion after subarachnoid haemorrhage?
Topics: Aneurysm, Ruptured; Cardiotonic Agents; Cerebral Angiography; Cerebrospinal Fluid Leak; Computed Tom | 2019 |
SARS-CoV-2 infection in an infant with severe dilated cardiomyopathy.
Topics: Cardiomyopathy, Dilated; Cardiotonic Agents; COVID-19; Diarrhea; Diuretics; Echocardiography; Entero | 2021 |
Does myocardial strain remain abnormal long after normalization of ejection fraction in patients with acute myocarditis?
Topics: Acute Disease; Adolescent; Atrioventricular Block; Cardiotonic Agents; Disease Progression; Echocard | 2019 |
Is Milrinone Effective for Infants with Mild-to-Moderate Congenital Diaphragmatic Hernia?
Topics: Female; Hernias, Diaphragmatic, Congenital; Humans; Hypertension, Pulmonary; Infant, Newborn; Male; | 2020 |
Adrenal function in preterm infants undergoing patent ductus arteriosus ligation.
Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Cardiotonic Agents; Cohort Studies; Ductus Arter | 2013 |
Neonatal circulatory failure due to acute hypertensive crisis: clinical and echocardiographic clues.
Topics: Acute Disease; Antihypertensive Agents; Aortic Valve Insufficiency; Arterial Pressure; Body Weight; | 2013 |
Loading conditions influence reliability of the echocardiographic ramp test in continuous-flow left ventricular assist devices.
Topics: Aged; Aspirin; Drug Therapy, Combination; Echocardiography; Eptifibatide; Heart-Assist Devices; Hemo | 2013 |
Effects of Combined Milrinone and Levosimendan Treatment on Systolic and Diastolic Function During Postischemic Myocardial Dysfunction in a Porcine Model.
Topics: Animals; Cardiotonic Agents; Diastole; Disease Models, Animal; Drug Therapy, Combination; Hydrazones | 2016 |
Oral Enoximone as an Alternative to Protracted Intravenous Medication in Severe Pediatric Myocardial Failure.
Topics: Adrenergic beta-Antagonists; Cardiotonic Agents; Child; Enoximone; Heart Failure; Hemodynamics; Huma | 2016 |
Sympathomimetic inefficiency in restoring contractility in the acute or chronic beta-blocker-treated ischaemic heart: comparison with a new agent.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cardiotonic Agents; Dobutamine; Dogs | 2008 |
The efficacy of intravenous milrinone in left ventricular restoration.
Topics: Aged; Cardiac Surgical Procedures; Cardiomyopathies; Cardiopulmonary Bypass; Cardiotonic Agents; Com | 2009 |
Low-dose β-blocker in combination with milrinone safely improves cardiac function and eliminates pulsus alternans in patients with acute decompensated heart failure.
Topics: Acute Disease; Adrenergic beta-Antagonists; Adult; Aged; Arrhythmias, Cardiac; Cardiotonic Agents; C | 2012 |
Combination of β-blocker and milrinone for acute heart failure.
Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Cardiotonic Agents; Female; Heart Failure; Hemody | 2012 |
Milrinone facilitates resuscitation from cardiac arrest and attenuates postresuscitation myocardial dysfunction.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cardiopulmonary Resuscitation; Combined Modality Thera | 2003 |
Left ventricular conditioning in the elderly patient to prevent congestive heart failure after transcatheter closure of atrial septal defect.
Topics: Aged; Aged, 80 and over; Cardiac Catheterization; Cardiotonic Agents; Catheterization; Diuretics; Do | 2005 |
Intravenous milrinone infusion improves congestive heart failure caused by diastolic dysfunction: a brief case series.
Topics: Adult; Aged; Cardiotonic Agents; Diastole; Echocardiography; Heart Failure; Humans; Infusions, Intra | 2005 |
Treatment of ischaemic left ventricular dysfunction with milrinone or dobutamine administered during coronary artery stenosis in the presence of beta blockade in pigs.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cardiac Output; Cardiotonic Agents; | 2006 |
Levosimendan in cardiac surgery: a unique drug for the treatment of perioperative left ventricular dysfunction or just another inodilator searching for a clinical application?
Topics: Adrenergic beta-Agonists; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cardiotonic Agents; D | 2007 |
Metabolic effects of phosphodiesterase III inhibitors: another reason to promote their use?
Topics: Cardiac Output, Low; Cardiotonic Agents; Energy Metabolism; Humans; Milrinone; Phosphodiesterase 3 I | 2007 |
Administration of milrinone before ischemia, in the presence of beta-blockade, to treat metabolic impairment and myocardial stunning in pigs.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Cardiac Output; Cardiotonic Agents; Coronary S | 2008 |
Effect of bolus milrinone on hemodynamic variables and pulmonary vascular resistance in patients with severe left ventricular dysfunction: a rapid test for reversibility of pulmonary hypertension.
Topics: Adult; Aged; Cardiac Output; Female; Heart Failure; Heart Transplantation; Hemodynamics; Humans; Hyp | 1996 |
Long-term hemodynamic responses to vasodilator therapy in patients with severe left ventricular dysfunction.
Topics: Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Female; Heart Transplantation; Hemod | 1999 |