milrinone has been researched along with Injury, Ischemia-Reperfusion in 17 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the efficacy of zinc oxide nanoparticles (ZnO-NPs) and/or milrinone (MIL) on renal ischemia/reperfusion injury (I/RI) in rats and their possible underlying mechanisms." | 8.31 | The combined effect of zinc oxide nanoparticles and milrinone on acute renal ischemia/reperfusion injury in rats: Potential underlying mechanisms. ( Abu-Heakal, N; Ali, IS; Awadin, W; Barakat, N; Elshal, MF; Embaby, EM; Marghani, BH; Saleh, RM, 2023) |
| "This experimental study aims to evaluate the efficacy of milrinone against ischaemia-reperfusion injury due to testicular torsion/detorsion." | 8.02 | Milrinone ameliorates ischaemia-reperfusion injury in experimental testicular torsion/detorsion rat model. ( Atılgan, D; Deresoy, FA; Katar, M; Kölükçü, E; Uluocak, N; Unsal, V, 2021) |
| " The phosphodiesterase-3 inhibitor, milrinone, has been reported to attenuate hepatic ischemia-reperfusion injury (IRI)." | 7.96 | Pretreatment with a Phosphodiesterase-3 Inhibitor, Milrinone, Reduces Hepatic Ischemia-Reperfusion Injury, Minimizing Pericentral Zone-Based Liver and Small Intestinal Injury in Rats. ( Fushida, S; Gabata, R; Hayashi, H; Makino, I; Miyashita, T; Nakanuma, S; Ohbatake, Y; Ohta, T; Okazaki, M; Sakai, S; Shinbashi, H; Tajima, H; Takamura, H, 2020) |
| "Our results confirmed that milrinone nebulization during warm ischemia maintained lung tissue adenosine triphosphate levels." | 7.74 | Potential for pulmonary protection by nebulized milrinone during warm ischemia. ( Aoyama, A; Bando, T; Chen, F; Fujinaga, T; Okamoto, T; Zhang, J, 2008) |
| "Acute cerebral hypoperfusion following subarachnoid hemorrhage (SAH) is highly related to the pathogenesis of delayed cerebral ischemia (DCI), but the therapeutic option is poorly available." | 5.46 | Neurocardiac protection with milrinone for restoring acute cerebral hypoperfusion and delayed ischemic injury after experimental subarachnoid hemorrhage. ( Ishikawa, T; Mutoh, T; Nakamura, K; Sasaki, K; Taki, Y; Tatewaki, Y, 2017) |
| "Milrinone treatment significantly decreased cerebral infarct size and reversed I/R-induced impairments in memory and motor coordination." | 5.36 | Pharmacological preconditioning by milrinone: memory preserving and neuroprotective effect in ischemia-reperfusion injury in mice. ( Jaggi, A; Saklani, R; Singh, N, 2010) |
| "Pulmonary hypertension was present in all groups following CPB." | 5.35 | Treating pulmonary hypertension post cardiopulmonary bypass in pigs: milrinone vs. sildenafil analog. ( Beaver, T; Kirby, DS; Klodell, C; Lobato, EB; Muehlschlegel, JD; Sidi, A; Urdaneta, F, 2008) |
| "To investigate the efficacy of zinc oxide nanoparticles (ZnO-NPs) and/or milrinone (MIL) on renal ischemia/reperfusion injury (I/RI) in rats and their possible underlying mechanisms." | 4.31 | The combined effect of zinc oxide nanoparticles and milrinone on acute renal ischemia/reperfusion injury in rats: Potential underlying mechanisms. ( Abu-Heakal, N; Ali, IS; Awadin, W; Barakat, N; Elshal, MF; Embaby, EM; Marghani, BH; Saleh, RM, 2023) |
| "This experimental study aims to evaluate the efficacy of milrinone against ischaemia-reperfusion injury due to testicular torsion/detorsion." | 4.02 | Milrinone ameliorates ischaemia-reperfusion injury in experimental testicular torsion/detorsion rat model. ( Atılgan, D; Deresoy, FA; Katar, M; Kölükçü, E; Uluocak, N; Unsal, V, 2021) |
| " The phosphodiesterase-3 inhibitor, milrinone, has been reported to attenuate hepatic ischemia-reperfusion injury (IRI)." | 3.96 | Pretreatment with a Phosphodiesterase-3 Inhibitor, Milrinone, Reduces Hepatic Ischemia-Reperfusion Injury, Minimizing Pericentral Zone-Based Liver and Small Intestinal Injury in Rats. ( Fushida, S; Gabata, R; Hayashi, H; Makino, I; Miyashita, T; Nakanuma, S; Ohbatake, Y; Ohta, T; Okazaki, M; Sakai, S; Shinbashi, H; Tajima, H; Takamura, H, 2020) |
| "We have previously reported that an increase of adenosine 3',5'-cyclic monophosphate (cAMP) in liver tissue after an administration of milrinone, a phosphodiesterase-3 inhibitor attenuates hepatic warm ischemia-reperfusion injury." | 3.75 | Implication of protein kinase A for a hepato-protective mechanism of milrinone pretreatment. ( Abe, Y; Kume, M; Sato, T; Satoh, K; Takahashi, T; Uchinami, H; Yakubouski, SV; Yamamoto, Y, 2009) |
| "Our results confirmed that milrinone nebulization during warm ischemia maintained lung tissue adenosine triphosphate levels." | 3.74 | Potential for pulmonary protection by nebulized milrinone during warm ischemia. ( Aoyama, A; Bando, T; Chen, F; Fujinaga, T; Okamoto, T; Zhang, J, 2008) |
| "Milrinone has been shown to be effective in the prevention of tissue damage due to oxidative stress and inflammatory process in the renal of warm ischemia in the experimental NHBDs model and in protecting the renal." | 1.48 | Investigation of the Effect of Milrinone on Renal Damage in an Experimental Non-Heart Beating Donor Model. ( Altınay, S; Batcıoglu, K; Ceylan, MS; Dokur, M; Karadag, M; Kazımoglu, H; Saygılı, Eİ; Uysal, E; Uyumlu, BA, 2018) |
| "Acute cerebral hypoperfusion following subarachnoid hemorrhage (SAH) is highly related to the pathogenesis of delayed cerebral ischemia (DCI), but the therapeutic option is poorly available." | 1.46 | Neurocardiac protection with milrinone for restoring acute cerebral hypoperfusion and delayed ischemic injury after experimental subarachnoid hemorrhage. ( Ishikawa, T; Mutoh, T; Nakamura, K; Sasaki, K; Taki, Y; Tatewaki, Y, 2017) |
| "Milrinone treatment significantly decreased cerebral infarct size and reversed I/R-induced impairments in memory and motor coordination." | 1.36 | Pharmacological preconditioning by milrinone: memory preserving and neuroprotective effect in ischemia-reperfusion injury in mice. ( Jaggi, A; Saklani, R; Singh, N, 2010) |
| "Pulmonary hypertension was present in all groups following CPB." | 1.35 | Treating pulmonary hypertension post cardiopulmonary bypass in pigs: milrinone vs. sildenafil analog. ( Beaver, T; Kirby, DS; Klodell, C; Lobato, EB; Muehlschlegel, JD; Sidi, A; Urdaneta, F, 2008) |
| "Milrinone is a phosphodiesterase 3 inhibitor that inhibits the breakdown of cyclic adenosine monophosphate and selectively relaxes smooth muscle." | 1.35 | Nebulized phosphodiesterase III inhibitor during warm ischemia attenuates pulmonary ischemia-reperfusion injury. ( Aoyama, A; Bando, T; Chen, F; Cui, Y; Date, H; Fujinaga, T; Okamoto, T; Sakai, H; Shoji, T; Zhang, J; Zhao, X, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (41.18) | 29.6817 |
| 2010's | 7 (41.18) | 24.3611 |
| 2020's | 3 (17.65) | 2.80 |
| Authors | Studies |
|---|---|
| Embaby, EM | 1 |
| Saleh, RM | 1 |
| Marghani, BH | 1 |
| Barakat, N | 1 |
| Awadin, W | 1 |
| Elshal, MF | 1 |
| Ali, IS | 1 |
| Abu-Heakal, N | 1 |
| Nakanuma, S | 1 |
| Tajima, H | 1 |
| Takamura, H | 1 |
| Sakai, S | 1 |
| Gabata, R | 1 |
| Okazaki, M | 1 |
| Shinbashi, H | 1 |
| Ohbatake, Y | 1 |
| Makino, I | 1 |
| Hayashi, H | 1 |
| Miyashita, T | 1 |
| Fushida, S | 1 |
| Ohta, T | 1 |
| Kölükçü, E | 1 |
| Atılgan, D | 1 |
| Uluocak, N | 1 |
| Deresoy, FA | 1 |
| Katar, M | 1 |
| Unsal, V | 1 |
| Uysal, E | 1 |
| Dokur, M | 1 |
| Altınay, S | 1 |
| Saygılı, Eİ | 1 |
| Batcıoglu, K | 1 |
| Ceylan, MS | 1 |
| Kazımoglu, H | 1 |
| Uyumlu, BA | 1 |
| Karadag, M | 1 |
| Gavra, P | 1 |
| Laflamme, M | 1 |
| Denault, AY | 1 |
| Théoret, Y | 1 |
| Perrault, LP | 1 |
| Varin, F | 1 |
| Steppan, J | 1 |
| Berkowitz, DE | 1 |
| Nyhan, D | 1 |
| Toyoda, T | 1 |
| Tosaka, S | 1 |
| Tosaka, R | 1 |
| Maekawa, T | 1 |
| Cho, S | 1 |
| Eguchi, S | 1 |
| Nakashima, M | 1 |
| Sumikawa, K | 1 |
| Mutoh, T | 2 |
| Sasaki, K | 1 |
| Nakamura, K | 1 |
| Tatewaki, Y | 1 |
| Ishikawa, T | 1 |
| Taki, Y | 1 |
| Urdaneta, F | 1 |
| Lobato, EB | 1 |
| Beaver, T | 1 |
| Muehlschlegel, JD | 1 |
| Kirby, DS | 1 |
| Klodell, C | 1 |
| Sidi, A | 1 |
| Chen, F | 2 |
| Zhang, J | 2 |
| Aoyama, A | 2 |
| Okamoto, T | 2 |
| Fujinaga, T | 2 |
| Bando, T | 2 |
| Satoh, K | 1 |
| Kume, M | 2 |
| Abe, Y | 1 |
| Uchinami, H | 1 |
| Yakubouski, SV | 1 |
| Takahashi, T | 1 |
| Sato, T | 1 |
| Yamamoto, Y | 2 |
| Zhao, X | 1 |
| Shoji, T | 1 |
| Sakai, H | 1 |
| Cui, Y | 1 |
| Date, H | 1 |
| Saklani, R | 1 |
| Jaggi, A | 1 |
| Singh, N | 1 |
| Nishiki, T | 1 |
| Kitada, H | 1 |
| Okabe, Y | 1 |
| Miura, Y | 1 |
| Kurihara, K | 1 |
| Kawanami, S | 1 |
| Tanaka, M | 1 |
| Banafsche, R | 1 |
| Yamaoka, Y | 1 |
| Nobiling, R | 1 |
| Gebhard, MM | 1 |
| Klar, E | 1 |
| Featherstone, RL | 1 |
| Chambers, DJ | 1 |
| Kelly, FJ | 1 |
| Ikegami, T | 1 |
| Nishizaki, T | 1 |
| Hiroshige, S | 1 |
| Ohta, R | 1 |
| Yanaga, K | 1 |
| Sugimachi, K | 1 |
17 other studies available for milrinone and Injury, Ischemia-Reperfusion
| Article | Year |
|---|---|
The combined effect of zinc oxide nanoparticles and milrinone on acute renal ischemia/reperfusion injury in rats: Potential underlying mechanisms.
Topics: Acute Kidney Injury; Animals; Caspase 3; Ischemia; Lipocalin-2; Male; Milrinone; Nanoparticles; NF-E | 2023 |
Pretreatment with a Phosphodiesterase-3 Inhibitor, Milrinone, Reduces Hepatic Ischemia-Reperfusion Injury, Minimizing Pericentral Zone-Based Liver and Small Intestinal Injury in Rats.
Topics: Animals; Intestine, Small; Ischemia; Ischemic Preconditioning; Liver; Male; Milrinone; Phosphodieste | 2020 |
Milrinone ameliorates ischaemia-reperfusion injury in experimental testicular torsion/detorsion rat model.
Topics: Animals; Humans; Male; Malondialdehyde; Milrinone; Rats; Rats, Wistar; Reperfusion Injury; Spermatic | 2021 |
Investigation of the Effect of Milrinone on Renal Damage in an Experimental Non-Heart Beating Donor Model.
Topics: Animals; Apoptosis; Disease Models, Animal; Female; Humans; Injections, Intraperitoneal; Kidney; Kid | 2018 |
Use of nebulized milrinone in cardiac surgery; Comparison of vibrating mesh and simple jet nebulizers.
Topics: Administration, Inhalation; Animals; Cardiopulmonary Bypass; Cardiotonic Agents; Endothelium, Vascul | 2017 |
Ischemic Postconditioning and Milrinone.
Topics: Animals; Disease Models, Animal; Ischemic Postconditioning; Milrinone; Myocardial Reperfusion Injury | 2018 |
Milrinone-induced postconditioning reduces hepatic ischemia-reperfusion injury in rats: the roles of phosphatidylinositol 3-kinase and nitric oxide.
Topics: Alanine Transaminase; Animals; Cyclic AMP-Dependent Protein Kinases; Ischemic Postconditioning; Live | 2014 |
Neurocardiac protection with milrinone for restoring acute cerebral hypoperfusion and delayed ischemic injury after experimental subarachnoid hemorrhage.
Topics: Animals; Brain Ischemia; Cardiotonic Agents; Cerebral Cortex; Echocardiography, Doppler; Heart; Male | 2017 |
Treating pulmonary hypertension post cardiopulmonary bypass in pigs: milrinone vs. sildenafil analog.
Topics: Acute Disease; Animals; Blood Pressure; Cardiopulmonary Bypass; Hypertension, Pulmonary; Milrinone; | 2008 |
Potential for pulmonary protection by nebulized milrinone during warm ischemia.
Topics: Adenine Nucleotides; Animals; Cyclic AMP; Ischemia; Lung; Male; Milrinone; Phosphodiesterase Inhibit | 2008 |
Implication of protein kinase A for a hepato-protective mechanism of milrinone pretreatment.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Pressure; Cyclic AMP; Cyclic AMP-D | 2009 |
Nebulized phosphodiesterase III inhibitor during warm ischemia attenuates pulmonary ischemia-reperfusion injury.
Topics: Aerosols; Animals; DNA Nucleotidylexotransferase; In Situ Nick-End Labeling; Lung; Lung Transplantat | 2009 |
Pharmacological preconditioning by milrinone: memory preserving and neuroprotective effect in ischemia-reperfusion injury in mice.
Topics: Animals; Brain Ischemia; Ischemic Preconditioning; Male; Maze Learning; Memory Disorders; Mice; Milr | 2010 |
Effect of milrinone on ischemia-reperfusion injury in the rat kidney.
Topics: Animals; Base Sequence; Blood Urea Nitrogen; Creatinine; DNA Primers; Kidney; Milrinone; Rats; Reper | 2011 |
Dynamic changes of post-ischemic hepatic microcirculation improved by a pre-treatment of phosphodiesterase-3 inhibitor, milrinone.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Blood Pressure; Cell Communication; Cell Survival; Cyc | 2006 |
Comparison of phosphodiesterase inhibitors of differing isoenzyme selectivity added to St. Thomas' hospital cardioplegic solution used for hypothermic preservation of rat lungs.
Topics: Animals; Bicarbonates; Calcium Chloride; Hypothermia, Induced; Lung; Lung Transplantation; Magnesium | 2000 |
Experimental study of a type 3 phosphodiesterase inhibitor on liver graft function.
Topics: Animals; Bile; Cyclic AMP; Graft Survival; Liver Transplantation; Male; Milrinone; Models, Animal; P | 2001 |