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milrinone and Inflammation

milrinone has been researched along with Inflammation in 11 studies

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this study was to evaluate the effect of preoperative inhalation of milrinone on cardiopulmonary bypass (CPB)-related inflammation."9.16Preoperative inhalation of milrinone attenuates inflammation in patients undergoing cardiac surgery with cardiopulmonary bypass. ( Gong, M; Lin, XZ; Lu, GT; Zheng, LJ, 2012)
" The authors evaluated the effects of milrinone on splanchnic oxygenation, systemic inflammation, and the subsequent acute-phase response in patients undergoing coronary artery bypass grafting."9.09Milrinone modulates endotoxemia, systemic inflammation, and subsequent acute phase response after cardiopulmonary bypass (CPB). ( Asfour, B; Berendes, E; Loick, HM; Möllhoff, T; Rolf, N; Schmidt, C; Tjan, TD; Van Aken, H, 1999)
"To investigate the usefulness of low-dose milrinone on gastric intramucosal pH (pHi) and systemic inflammation in patients undergoing hypothermic cardiopulmonary bypass (CPB)."9.09Effect of low-dose milrinone on gastric intramucosal pH and systemic inflammation after hypothermic cardiopulmonary bypass. ( Akiyoshi, K; Irita, K; Okamoto, H; Takahashi, S; Taniyama, T; Yamaura, K, 2001)
" Whether biomarkers of myocardial necrosis, inflammation and apoptosis change in response to acute milrinone administration is not well established."7.75Short term effects of milrinone on biomarkers of necrosis, apoptosis, and inflammation in patients with severe heart failure. ( Bazari, R; Czerska, B; Gupta, RC; Hasan, R; Lanfear, DE; Sabbah, HN; Tita, C; Williams, C, 2009)
"The purpose of this study was to evaluate the effect of preoperative inhalation of milrinone on cardiopulmonary bypass (CPB)-related inflammation."5.16Preoperative inhalation of milrinone attenuates inflammation in patients undergoing cardiac surgery with cardiopulmonary bypass. ( Gong, M; Lin, XZ; Lu, GT; Zheng, LJ, 2012)
" The authors evaluated the effects of milrinone on splanchnic oxygenation, systemic inflammation, and the subsequent acute-phase response in patients undergoing coronary artery bypass grafting."5.09Milrinone modulates endotoxemia, systemic inflammation, and subsequent acute phase response after cardiopulmonary bypass (CPB). ( Asfour, B; Berendes, E; Loick, HM; Möllhoff, T; Rolf, N; Schmidt, C; Tjan, TD; Van Aken, H, 1999)
"To investigate the usefulness of low-dose milrinone on gastric intramucosal pH (pHi) and systemic inflammation in patients undergoing hypothermic cardiopulmonary bypass (CPB)."5.09Effect of low-dose milrinone on gastric intramucosal pH and systemic inflammation after hypothermic cardiopulmonary bypass. ( Akiyoshi, K; Irita, K; Okamoto, H; Takahashi, S; Taniyama, T; Yamaura, K, 2001)
" Whether biomarkers of myocardial necrosis, inflammation and apoptosis change in response to acute milrinone administration is not well established."3.75Short term effects of milrinone on biomarkers of necrosis, apoptosis, and inflammation in patients with severe heart failure. ( Bazari, R; Czerska, B; Gupta, RC; Hasan, R; Lanfear, DE; Sabbah, HN; Tita, C; Williams, C, 2009)
" Milrinone, a phosphodiesterase (PDE)-3 inhibitor, is frequently used to treat perioperative pulmonary hypertension."3.73Zaprinast attenuates hypoxic pulmonary artery injury and causes less aortic relaxation than milrinone. ( Crisostomo, P; Kher, A; Meldrum, DR; Pitcher, JM; Tsai, BM; Wang, M, 2005)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's6 (54.55)29.6817
2010's2 (18.18)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Ručilová, V1
Świerczek, A1
Vanda, D1
Funk, P1
Lemrová, B1
Gawalska, A1
Bucki, A1
Nowak, B1
Zadrożna, M1
Pociecha, K1
Soural, M1
Wyska, E1
Pawłowski, M1
Chłoń-Rzepa, G1
Zajdel, P1
Han, Y1
Hou, R1
Zhang, X1
Liu, H1
Gao, Y1
Li, X1
Qi, R1
Cai, R1
Qi, Y1
Lanfear, DE1
Hasan, R1
Gupta, RC1
Williams, C1
Czerska, B1
Tita, C1
Bazari, R1
Sabbah, HN1
Gong, M1
Lin, XZ1
Lu, GT1
Zheng, LJ1
Chanani, NK1
Cowan, DB1
Takeuchi, K1
Poutias, DN1
Garcia, LM1
del Nido, PJ1
McGowan, FX1
Takeno, M1
Takagi, S1
Sakuragi, S1
Suzuki, S1
Tsutsumi, Y1
Nonogi, H1
Goto, Y1
Tsai, BM1
Wang, M1
Pitcher, JM1
Kher, A1
Crisostomo, P1
Meldrum, DR1
White, M1
Ducharme, A1
Ibrahim, R1
Whittom, L1
Lavoie, J1
Guertin, MC1
Racine, N1
He, Y1
Yao, G1
Rouleau, JL1
Schiffrin, EL1
Touyz, RM1
Möllhoff, T1
Loick, HM1
Van Aken, H1
Schmidt, C1
Rolf, N1
Tjan, TD1
Asfour, B1
Berendes, E1
Yamaura, K1
Okamoto, H1
Akiyoshi, K1
Irita, K1
Taniyama, T1
Takahashi, S1

Trials

4 trials available for milrinone and Inflammation

ArticleYear
Preoperative inhalation of milrinone attenuates inflammation in patients undergoing cardiac surgery with cardiopulmonary bypass.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2012, Volume: 21, Issue:1

    Topics: Administration, Inhalation; Analysis of Variance; Cardiopulmonary Bypass; Cytokines; Female; Hemodyn

2012
Increased systemic inflammation and oxidative stress in patients with worsening congestive heart failure: improvement after short-term inotropic support.
    Clinical science (London, England : 1979), 2006, Volume: 110, Issue:4

    Topics: Biomarkers; C-Reactive Protein; Cardiotonic Agents; Case-Control Studies; Cell Adhesion Molecules; C

2006
Milrinone modulates endotoxemia, systemic inflammation, and subsequent acute phase response after cardiopulmonary bypass (CPB).
    Anesthesiology, 1999, Volume: 90, Issue:1

    Topics: Acute-Phase Reaction; C-Reactive Protein; Cardiopulmonary Bypass; Double-Blind Method; Endotoxemia;

1999
Effect of low-dose milrinone on gastric intramucosal pH and systemic inflammation after hypothermic cardiopulmonary bypass.
    Journal of cardiothoracic and vascular anesthesia, 2001, Volume: 15, Issue:2

    Topics: Body Temperature; Carbon Dioxide; Cardiopulmonary Bypass; Cytokines; Echocardiography, Transesophage

2001

Other Studies

7 other studies available for milrinone and Inflammation

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
New imidazopyridines with phosphodiesterase 4 and 7 inhibitory activity and their efficacy in animal models of inflammatory and autoimmune diseases.
    European journal of medicinal chemistry, 2021, Jan-01, Volume: 209

    Topics: Animals; Anti-Inflammatory Agents; Autoimmune Diseases; Cyclic Nucleotide Phosphodiesterases, Type 7

2021
Amlexanox exerts anti-inflammatory actions by targeting phosphodiesterase 4B in lipopolysaccharide-activated macrophages.
    Biochimica et biophysica acta. Molecular cell research, 2020, Volume: 1867, Issue:10

    Topics: Aminopyridines; Animals; Anti-Inflammatory Agents; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases,

2020
Short term effects of milrinone on biomarkers of necrosis, apoptosis, and inflammation in patients with severe heart failure.
    Journal of translational medicine, 2009, Jul-29, Volume: 7

    Topics: Adult; Aged; Apoptosis; Biomarkers; Cardiotonic Agents; Dose-Response Relationship, Drug; Fas Ligand

2009
Differential effects of amrinone and milrinone upon myocardial inflammatory signaling.
    Circulation, 2002, Sep-24, Volume: 106, Issue:12 Suppl 1

    Topics: Amrinone; Animals; Anti-Inflammatory Agents; Cardiotonic Agents; Cell Line; Cells, Cultured; Cycloox

2002
Continuous milrinone infusion during preoperative anti-inflammatory therapy in inflammatory aortic aneurysm complicating severe congestive heart failure.
    Heart and vessels, 2002, Volume: 17, Issue:1

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Aortic Aneurysm, Thoracic; Aortic Valve Insuffici

2002
Zaprinast attenuates hypoxic pulmonary artery injury and causes less aortic relaxation than milrinone.
    Shock (Augusta, Ga.), 2005, Volume: 24, Issue:5

    Topics: Animals; Aorta; Aorta, Thoracic; Dose-Response Relationship, Drug; Drug Synergism; Hypertension, Pul

2005