milrinone has been researched along with Hypertension, Pulmonary in 101 studies
Hypertension, Pulmonary: Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the impact of milrinone administration on time spent on nitric oxide (iNO) in infants with acute pulmonary hypertension (aPH)." | 9.69 | The use of milrinone in neonates with persistent pulmonary hypertension of the newborn - a randomised controlled trial pilot study (MINT 1). ( Breatnach, C; Bussmann, N; Cleary, B; de Boode, WP; Dempsey, E; El-Khuffash, A; Feeney, O; Franklin, O; Griffin, J; McNamara, PJ; Smith, A; Tully, E, 2023) |
| "To compare the effects of dobutamine and nitroglycerin to milrinone in young patients with severe pulmonary hypertension undergoing mitral valve replacement." | 9.27 | Dobutamine and Nitroglycerin Versus Milrinone for Perioperative Management of Pulmonary Hypertension in Mitral Valve Surgery. A Randomized Controlled Study. ( Abu Elkassem, MS; Elmiligy, AE; Eskandr, AM; Hussein, L; Metwally, AA; Mourad, M; Sadik, SA, 2018) |
| "To compare the effects of inhaled milrinone and levosimendan on pulmonary and systemic hemodynamics in patients with pulmonary hypertension." | 9.27 | The Effect of Inhaled Milrinone Versus Inhaled Levosimendan in Pulmonary Hypertension Patients Undergoing Mitral Valve Surgery - A Pilot Randomized Double-Blind Study. ( Gandham, R; Kaur, P; Kundra, TS; Manjunatha, N; Prabhakar, V, 2018) |
| "To compare the effects of levosimendan with milrinone in cardiac surgical patients with pulmonary hypertension and left ventricular dysfunction." | 9.22 | Comparative Effect of Levosimendan and Milrinone in Cardiac Surgery Patients With Pulmonary Hypertension and Left Ventricular Dysfunction. ( Arya, VK; Dutta, V; Kumar, B; Mishra, A; Mishra, AK, 2016) |
| "An open label study of milrinone in neonates with persistent pulmonary hypertension of the newborn was conducted." | 9.17 | Pharmacology of milrinone in neonates with persistent pulmonary hypertension of the newborn and suboptimal response to inhaled nitric oxide. ( Freeman, D; McNamara, PJ; Sahni, M; Shivananda, SP; Taddio, A, 2013) |
| " The aim of this study was to investigate the postoperative hemodynamic effects of milrinone inhalation, and determine whether it has a selective effect of pulmonary vasodilation in patients with pulmonary hypertension undergoing mitral valve replacement surgery." | 9.14 | Comparison of inhaled and intravenous milrinone in patients with pulmonary hypertension undergoing mitral valve surgery. ( Dai, A; Gong, M; Wang, H; Zhou, B, 2009) |
| "In end-stage congestive cardiac failure, intravenous milrinone and sildenafil both cause similar reductions in systemic and pulmonary vascular resistance; however, milrinone has more cardiac selective effects on left ventricular filling and heart rate." | 9.14 | Acute hemodynamic effects of intravenous sildenafil citrate in congestive heart failure: comparison of phosphodiesterase type-3 and -5 inhibition. ( Botha, P; Dark, JH; Macgowan, GA; Parry, G, 2009) |
| "The phosphodiesterase inhibitor milrinone is usually preferred in patients with pulmonary hypertension and myocardial dysfunction after cardiopulmonary bypass." | 9.12 | Effects of low-dose milrinone on weaning from cardiopulmonary bypass and after in patients with mitral stenosis and pulmonary hypertension. ( Canik, S; Goksel, O; Issever, H; Oztekin, DS; Oztekin, I; Yazici, S, 2007) |
| "Treatment of pulmonary hypertension in adult cardiac surgery patients with inhaled nitric oxide compared with milrinone is associated with lower heart rates, higher right ventricular ejection fraction, and a lower requirement for treatment with vasopressor agents." | 9.09 | A comparison of inhaled nitric oxide and milrinone for the treatment of pulmonary hypertension in adult cardiac surgery patients. ( Cody, R; Ginsberg, S; Grubb, W; Krause, T; Papp, D; Pena, LL; Scholz, P; Solina, A, 2000) |
| "To evaluate and compare the hemodynamic effects of intraoperative intravenous milrinone versus inhalational milrinone at two timepoints in patients with severe pulmonary hypertension undergoing mitral valve surgery." | 8.02 | Inhaled versus intravenous milrinone in mitral stenosis with pulmonary hypertension. ( Garg, P; Patel, J; Patel, K; Patel, S, 2021) |
| "After hypercapnia pulmonary hypertension, swine were administered equivalent inhaled milrinone doses of 15 or 50 µg/kg through simple jet nebulization, vibrating mesh nebulization, intratracheal instillation, and intratracheal atomization." | 7.88 | Pharmacokinetics and Pharmacodynamics of Nebulized and Intratracheal Milrinone in a Swine Model of Hypercapnia Pulmonary Hypertension. ( Denault, AY; Gavra, P; Perrault, LP; Théoret, Y; Varin, F, 2018) |
| " The aim of this study was to retrospectively evaluate the effect of inhaled milrinone versus inhaled iloprost in patients with persistent pulmonary hypertension following discontinuation of CPB." | 7.85 | A retrospective comparison of inhaled milrinone and iloprost in post-bypass pulmonary hypertension. ( Antoniou, T; Leontiadis, E; Perreas, K; Rellia, P; Thanopoulos, A; Theodoraki, K; Zarkalis, D, 2017) |
| "Milrinone may be an appropriate adjuvant therapy for infants with persistent pulmonary hypertension of the newborn." | 7.83 | The effect of milrinone on right and left ventricular function when used as a rescue therapy for term infants with pulmonary hypertension. ( Corcoran, JD; El-Khuffash, AF; Franklin, O; James, AT; McNamara, PJ, 2016) |
| "Milrinone has been proposed as an effective treatment for pulmonary hypertension (PH) and right ventricular (RV) dysfunction." | 7.81 | Treatment of premature infants with pulmonary hypertension and right ventricular dysfunction with milrinone: a case series. ( Bee, C; Corcoran, JD; El-Khuffash, AF; Franklin, O; James, AT; McNamara, PJ, 2015) |
| "Preemptive treatment of pulmonary hypertension with a combination of inhaled prostacyclin and milrinone before CPB was associated with a reduction in the severity of pulmonary hypertension." | 7.81 | Preliminary experience with combined inhaled milrinone and prostacyclin in cardiac surgical patients with pulmonary hypertension. ( Carrier, M; Denault, AY; Elmi-Sarabi, M; Fortier, A; Laflamme, M; Perrault, LP, 2015) |
| "Both milrinone and UK 343-664 partially reversed thromboxane-induced pulmonary hypertension, with a notable decrease in mean pulmonary artery pressure and pulmonary vascular resistance and a concomitant increase in cardiac output." | 7.72 | Effects of a new phosphodiesterase enzyme type V inhibitor (UK 343-664) versus milrinone in a porcine model of acute pulmonary hypertension. ( Beaver, T; Kirby, DS; Lobato, EB; Naik, B; Urdaneta, F; Willert, JL, 2004) |
| "We tested whether aerosolized milrinone in lambs selectively reduces drug-induced acute pulmonary hypertension without reducing the mean systemic blood pressure (MSBP)." | 7.72 | Effect of aerosolized milrinone during drug-induced pulmonary hypertension in lambs. ( Fakioglu, H; Gelvez, J; Olarte, JL; Soliz, A; Torbati, D; Totapally, BR, 2004) |
| "We conclude that milrinone is effective in the management of pulmonary hypertension following CPB in children who underwent TOF repair." | 7.70 | Effect of milrinone on postbypass pulmonary hypertension in children after tetralogy of Fallot repair. ( Chow, LH; Chu, CC; Lee, TY; Lin, SM; New, SH; Ting, CK; Tsai, SK; Tsou, MY, 2000) |
| "We studied the effects of milrinone on serotonin-induced pulmonary hypertension and bronchoconstriction in dogs." | 7.70 | Milrinone attenuates serotonin-induced pulmonary hypertension and bronchoconstriction in dogs. ( Hashiba, E; Hashimoto, Y; Hirota, K; Kudo, T; Matsuki, A; Sato, T; Yoshioka, H, 2000) |
| "In the setting of monocrotaline pyrrole-induced recipient pulmonary hypertension, milrinone was associated with significant improvements in pulmonary vascular impedance, right ventricular function, and transpulmonary efficiency." | 7.70 | Hemodynamic and inotropic effects of milrinone after heart transplantation in the setting of recipient pulmonary hypertension. ( Bittner, HB; Chen, EP; Davis, RD; Van Trigt, P, 1998) |
| "To determine whether inhaled nitric oxide (IN0) and intravenous milrinone have additive pulmonary vasodilator effects in a rat model of pulmonary hypertension." | 7.70 | Additive effects of inhaled nitric oxide and intravenous milrinone in experimental pulmonary hypertension. ( Bradford, K; Deb, B; Pearl, RG, 2000) |
| "The induction of pulmonary hypertension decreased the platelet count and increased the plasma levels of thromboxane B2 and 6-keto-prostaglandin F1alpha." | 7.70 | Effects of milrinone on platelet aggregation in swine with pulmonary hypertension. ( Kazama, M; Kobayashi, K; Miyajima, Y; Tajimi, K; Tanaka, H, 2000) |
| "This investigation demonstrates the well-known hemodynamic and inotropic effects of milrinone which, in the setting of monocrotaline pyrrole-induced pulmonary hypertension, were also associated with significant increases in pulmonary blood flow and left ventricular filling." | 7.69 | Milrinone improves pulmonary hemodynamics and right ventricular function in chronic pulmonary hypertension. ( Bittner, HB; Chen, EP; Davis, RD; Van Trigt, P, 1997) |
| "Bolus milrinone consistently decreases PVR in patients with pulmonary hypertension secondary to severe heart failure." | 7.69 | Effect of bolus milrinone on hemodynamic variables and pulmonary vascular resistance in patients with severe left ventricular dysfunction: a rapid test for reversibility of pulmonary hypertension. ( Colucci, WS; Gauthier, DF; Givertz, MM; Hare, JM; Loh, E, 1996) |
| " The present study shows the effects of MIL on the pulmonary circulation in dogs with pulmonary hypertension due to autologous muscle-induced pulmonary embolism, and also demonstrates a comparison with those of dopamine and dobutamine." | 7.68 | Vasodilatory effects of milrinone on pulmonary vasculature in dogs with pulmonary hypertension due to pulmonary embolism: a comparison with those of dopamine and dobutamine. ( Kobayashi, K; Matsumoto, A; Tajimi, K; Tanaka, H, 1990) |
| "Milrinone may have a selective pulmonary vasodilatory effect only in dogs with pulmonary hypertension." | 7.68 | Effects of milrinone on pulmonary vasculature in normal dogs and in dogs with pulmonary hypertension. ( Kobayashi, K; Moritsune, O; Okada, K; Tajimi, K; Tanaka, H, 1991) |
| "To evaluate the effects of milrinone (MIL) on hemodynamics and lung water content, we used 10 mongrel dogs with pulmonary hypertension (PH)." | 7.68 | Effects of milrinone on lung water content in dogs with acute pulmonary hypertension. ( Kobayashi, K; Matsumoto, A; Tajimi, K; Tanaka, H, 1992) |
| "To assess the impact of milrinone administration on time spent on nitric oxide (iNO) in infants with acute pulmonary hypertension (aPH)." | 5.69 | The use of milrinone in neonates with persistent pulmonary hypertension of the newborn - a randomised controlled trial pilot study (MINT 1). ( Breatnach, C; Bussmann, N; Cleary, B; de Boode, WP; Dempsey, E; El-Khuffash, A; Feeney, O; Franklin, O; Griffin, J; McNamara, PJ; Smith, A; Tully, E, 2023) |
| " Our aim was to compare acute dose-response hemodynamic effects of inodilators dobutamine (DOB), milrinone (MIL), and levosimendan (LEV) in chronic experimental PH." | 5.46 | Dose-Response Head-to-Head Comparison of Inodilators Dobutamine, Milrinone, and Levosimendan in Chronic Experimental Pulmonary Hypertension. ( Alaa, M; Leite, S; Leite-Moreira, AF; Lopes, L; Lourenço, AP; Oliveira-Pinto, J; Tavares-Silva, M, 2017) |
| "Milrinone use was associated with an improvement in systolic and diastolic function in the RV, corresponding to an improvement in clinical status." | 5.38 | Use of milrinone to treat cardiac dysfunction in infants with pulmonary hypertension secondary to congenital diaphragmatic hernia: a review of six patients. ( Patel, N, 2012) |
| "Secondary pulmonary hypertension is a frequent condition after heart valve surgery." | 5.36 | Combined usage of inhaled and intravenous milrinone in pulmonary hypertension after heart valve surgery. ( Bulat, C; Carev, M; Husedzinović, I; Jercić, A; Karanović, N; Letica, D; Lojpur, M; Marovih, Z; Nenadić, D, 2010) |
| "Pulmonary hypertension was present in all groups following CPB." | 5.35 | Treating pulmonary hypertension post cardiopulmonary bypass in pigs: milrinone vs. sildenafil analog. ( Beaver, T; Kirby, DS; Klodell, C; Lobato, EB; Muehlschlegel, JD; Sidi, A; Urdaneta, F, 2008) |
| "Pretreatment with milrinone markedly enhanced relaxation to prostacyclin and iloprost in PPHN PA, similar to relaxation in control PA." | 5.35 | Milrinone enhances relaxation to prostacyclin and iloprost in pulmonary arteries isolated from lambs with persistent pulmonary hypertension of the newborn. ( Chen, B; Farrow, KN; Gugino, SF; Kumar, VH; Lakshminrusimha, S; Porta, NF; Russell, JA; Steinhorn, RH, 2009) |
| "Inhaled milrinone administered before cardiopulmonary bypass (CPB) reduces the severity of pulmonary hypertension during cardiac surgery." | 5.34 | Inhaled milrinone in cardiac surgical patients: a pilot randomized controlled trial of jet vs. mesh nebulization. ( Denault, AY; Nguyen, AQ; Perrault, LP; Théoret, Y; Varin, F, 2020) |
| "Most patients with congestive heart failure (CHF) develop pulmonary venous hypertension, but right ventricular afterload is frequently further elevated by increased pulmonary vascular resistance." | 5.34 | Inhalation of the phosphodiesterase-3 inhibitor milrinone attenuates pulmonary hypertension in a rat model of congestive heart failure. ( Habbazettl, H; Hentschel, T; Koster, A; Kuebler, WM; Kuppe, H; Riad, A; Tschope, C; Weimann, J; Yin, N, 2007) |
| "Milrinone is a promising adjunctive therapy because of its pulmonary vasodilator properties and cardiotropic effects." | 5.33 | Milrinone improves oxygenation in neonates with severe persistent pulmonary hypertension of the newborn. ( Laique, F; McNamara, PJ; Muang-In, S; Whyte, HE, 2006) |
| "Pulmonary hypertension was induced with a continuous infusion of the thromboxane analogue, U46619." | 5.33 | Treatment with phosphodiesterase inhibitors type III and V: milrinone and sildenafil is an effective combination during thromboxane-induced acute pulmonary hypertension. ( Beaver, T; Kirby, DS; Klodell, C; Lobato, EB; Muehlschlegel, J; Sidi, A, 2006) |
| "A 65-year-old female with mitral regurgitation was scheduled for the mitral valve surgery." | 5.32 | [The use of milrinone in a patient with mitral regurgitation and severe pulmonary hypertension: a case report]. ( Arisaka, H; Katori, N; Tagawa, M; Takeda, J; Yamada, T; Yamamoto, S, 2003) |
| "Pulmonary hypertension in patients with congestive heart failure (CHF) is a risk factor for increased mortality after orthotopic cardiac transplantation." | 5.30 | The use of milrinone in pre-transplant assessment of patients with congestive heart failure and pulmonary hypertension. ( Abel, JG; Carere, RG; Cook, RC; D'yachkova, Y; Ignaszewski, AP; Pamboukian, SV; Webb, JG, 1999) |
| "Milrinone is a phosphodiesterase inhibitor that has vasorelaxant activity." | 5.29 | [Acute effect of milrinone on pulmonary hemodynamics in patients with hypoxic pulmonary hypertension]. ( Chen, W; Cheng, D; Jiang, J, 1995) |
| "To compare the effects of dobutamine and nitroglycerin to milrinone in young patients with severe pulmonary hypertension undergoing mitral valve replacement." | 5.27 | Dobutamine and Nitroglycerin Versus Milrinone for Perioperative Management of Pulmonary Hypertension in Mitral Valve Surgery. A Randomized Controlled Study. ( Abu Elkassem, MS; Elmiligy, AE; Eskandr, AM; Hussein, L; Metwally, AA; Mourad, M; Sadik, SA, 2018) |
| "To compare the effects of inhaled milrinone and levosimendan on pulmonary and systemic hemodynamics in patients with pulmonary hypertension." | 5.27 | The Effect of Inhaled Milrinone Versus Inhaled Levosimendan in Pulmonary Hypertension Patients Undergoing Mitral Valve Surgery - A Pilot Randomized Double-Blind Study. ( Gandham, R; Kaur, P; Kundra, TS; Manjunatha, N; Prabhakar, V, 2018) |
| "Inhaled milrinone (iMil) has been used for the treatment of pulmonary hypertension (PH) but its efficacy, safety, and prophylactic effects in facilitating separation from cardiopulmonary bypass (CPB) and preventing right ventricular (RV) dysfunction have not yet been evaluated in a clinical trial." | 5.22 | A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients. ( Arellano, R; Bussières, JS; Denault, AY; Elmi-Sarabi, M; Finegan, B; Fortier, A; Gavra, P; Haddad, F; Lambert, J; Levesque, S; Nguyen, AQN; Perrault, LP; Shi, Y; Tardif, JC; Varin, F, 2016) |
| "To compare the effects of levosimendan with milrinone in cardiac surgical patients with pulmonary hypertension and left ventricular dysfunction." | 5.22 | Comparative Effect of Levosimendan and Milrinone in Cardiac Surgery Patients With Pulmonary Hypertension and Left Ventricular Dysfunction. ( Arya, VK; Dutta, V; Kumar, B; Mishra, A; Mishra, AK, 2016) |
| "An open label study of milrinone in neonates with persistent pulmonary hypertension of the newborn was conducted." | 5.17 | Pharmacology of milrinone in neonates with persistent pulmonary hypertension of the newborn and suboptimal response to inhaled nitric oxide. ( Freeman, D; McNamara, PJ; Sahni, M; Shivananda, SP; Taddio, A, 2013) |
| "In end-stage congestive cardiac failure, intravenous milrinone and sildenafil both cause similar reductions in systemic and pulmonary vascular resistance; however, milrinone has more cardiac selective effects on left ventricular filling and heart rate." | 5.14 | Acute hemodynamic effects of intravenous sildenafil citrate in congestive heart failure: comparison of phosphodiesterase type-3 and -5 inhibition. ( Botha, P; Dark, JH; Macgowan, GA; Parry, G, 2009) |
| " The aim of this study was to investigate the postoperative hemodynamic effects of milrinone inhalation, and determine whether it has a selective effect of pulmonary vasodilation in patients with pulmonary hypertension undergoing mitral valve replacement surgery." | 5.14 | Comparison of inhaled and intravenous milrinone in patients with pulmonary hypertension undergoing mitral valve surgery. ( Dai, A; Gong, M; Wang, H; Zhou, B, 2009) |
| " Milrinone, a phosphodiesterase type 3 (PDE3) inhibitor, can also reduce PVR for postoperative patients with pulmonary hypertension." | 5.13 | Nitric oxide in conjunction with milrinone better stabilized pulmonary hemodynamics after Fontan procedure. ( Cai, J; Chen, L; Ding, W; Liu, J; Shi, Z; Su, Z; Xu, Z; Yang, Y; Yu, X; Zhou, Y, 2008) |
| "The phosphodiesterase inhibitor milrinone is usually preferred in patients with pulmonary hypertension and myocardial dysfunction after cardiopulmonary bypass." | 5.12 | Effects of low-dose milrinone on weaning from cardiopulmonary bypass and after in patients with mitral stenosis and pulmonary hypertension. ( Canik, S; Goksel, O; Issever, H; Oztekin, DS; Oztekin, I; Yazici, S, 2007) |
| "Treatment of pulmonary hypertension in adult cardiac surgery patients with inhaled nitric oxide compared with milrinone is associated with lower heart rates, higher right ventricular ejection fraction, and a lower requirement for treatment with vasopressor agents." | 5.09 | A comparison of inhaled nitric oxide and milrinone for the treatment of pulmonary hypertension in adult cardiac surgery patients. ( Cody, R; Ginsberg, S; Grubb, W; Krause, T; Papp, D; Pena, LL; Scholz, P; Solina, A, 2000) |
| "We reviewed the charts of eight adult patients with postoperative pulmonary hypertension who received oral sildenafil (25 to 50 mg) to facilitate weaning of IV (milrinone, nitroglycerine, and sodium nitroprusside) and inhaled (nitric oxide) pulmonary vasodilators." | 4.82 | Oral sildenafil reduces pulmonary hypertension after cardiac surgery. ( Beaver, TM; Hess, PJ; Klodell, CT; Lobato, EB; Martin, TD; Staples, ED; Trachte, AL; Urdaneta, F, 2005) |
| "To evaluate and compare the hemodynamic effects of intraoperative intravenous milrinone versus inhalational milrinone at two timepoints in patients with severe pulmonary hypertension undergoing mitral valve surgery." | 4.02 | Inhaled versus intravenous milrinone in mitral stenosis with pulmonary hypertension. ( Garg, P; Patel, J; Patel, K; Patel, S, 2021) |
| "After hypercapnia pulmonary hypertension, swine were administered equivalent inhaled milrinone doses of 15 or 50 µg/kg through simple jet nebulization, vibrating mesh nebulization, intratracheal instillation, and intratracheal atomization." | 3.88 | Pharmacokinetics and Pharmacodynamics of Nebulized and Intratracheal Milrinone in a Swine Model of Hypercapnia Pulmonary Hypertension. ( Denault, AY; Gavra, P; Perrault, LP; Théoret, Y; Varin, F, 2018) |
| " The aim of this study was to retrospectively evaluate the effect of inhaled milrinone versus inhaled iloprost in patients with persistent pulmonary hypertension following discontinuation of CPB." | 3.85 | A retrospective comparison of inhaled milrinone and iloprost in post-bypass pulmonary hypertension. ( Antoniou, T; Leontiadis, E; Perreas, K; Rellia, P; Thanopoulos, A; Theodoraki, K; Zarkalis, D, 2017) |
| "Milrinone may be an appropriate adjuvant therapy for infants with persistent pulmonary hypertension of the newborn." | 3.83 | The effect of milrinone on right and left ventricular function when used as a rescue therapy for term infants with pulmonary hypertension. ( Corcoran, JD; El-Khuffash, AF; Franklin, O; James, AT; McNamara, PJ, 2016) |
| "Milrinone has been proposed as an effective treatment for pulmonary hypertension (PH) and right ventricular (RV) dysfunction." | 3.81 | Treatment of premature infants with pulmonary hypertension and right ventricular dysfunction with milrinone: a case series. ( Bee, C; Corcoran, JD; El-Khuffash, AF; Franklin, O; James, AT; McNamara, PJ, 2015) |
| "Preemptive treatment of pulmonary hypertension with a combination of inhaled prostacyclin and milrinone before CPB was associated with a reduction in the severity of pulmonary hypertension." | 3.81 | Preliminary experience with combined inhaled milrinone and prostacyclin in cardiac surgical patients with pulmonary hypertension. ( Carrier, M; Denault, AY; Elmi-Sarabi, M; Fortier, A; Laflamme, M; Perrault, LP, 2015) |
| "Milrinone administered through inhalation is an emerging method aimed at specifically reducing pulmonary hypertension without affecting systemic pressures." | 3.80 | A specific and sensitive HPLC-MS/MS micromethod for milrinone plasma levels determination after inhalation in cardiac patients. ( Denault, AY; Gavra, P; Litalien, C; Nguyen, AQ; Theoret, Y; Varin, F, 2014) |
| "Twenty-six infants with pulmonary hypertension undergoing ventricular septum defect repair were retrospectively allocated to milrinone group (n= 13)and olprinone group(n=13)." | 3.79 | [Comparison of the effects of phosphodiesterase III inhibitors, milrinone and olprinone, in infant corrective cardiac surgery]. ( Izumi, K; Jimi, N; Mizuno, K; Sakimura, S; Sumiyoshi, R; Yoshino, J, 2013) |
| " Milrinone, a phosphodiesterase (PDE)-3 inhibitor, is frequently used to treat perioperative pulmonary hypertension." | 3.73 | Zaprinast attenuates hypoxic pulmonary artery injury and causes less aortic relaxation than milrinone. ( Crisostomo, P; Kher, A; Meldrum, DR; Pitcher, JM; Tsai, BM; Wang, M, 2005) |
| "Both milrinone and UK 343-664 partially reversed thromboxane-induced pulmonary hypertension, with a notable decrease in mean pulmonary artery pressure and pulmonary vascular resistance and a concomitant increase in cardiac output." | 3.72 | Effects of a new phosphodiesterase enzyme type V inhibitor (UK 343-664) versus milrinone in a porcine model of acute pulmonary hypertension. ( Beaver, T; Kirby, DS; Lobato, EB; Naik, B; Urdaneta, F; Willert, JL, 2004) |
| "We tested whether aerosolized milrinone in lambs selectively reduces drug-induced acute pulmonary hypertension without reducing the mean systemic blood pressure (MSBP)." | 3.72 | Effect of aerosolized milrinone during drug-induced pulmonary hypertension in lambs. ( Fakioglu, H; Gelvez, J; Olarte, JL; Soliz, A; Torbati, D; Totapally, BR, 2004) |
| "To determine whether inhaled nitric oxide (IN0) and intravenous milrinone have additive pulmonary vasodilator effects in a rat model of pulmonary hypertension." | 3.70 | Additive effects of inhaled nitric oxide and intravenous milrinone in experimental pulmonary hypertension. ( Bradford, K; Deb, B; Pearl, RG, 2000) |
| "The induction of pulmonary hypertension decreased the platelet count and increased the plasma levels of thromboxane B2 and 6-keto-prostaglandin F1alpha." | 3.70 | Effects of milrinone on platelet aggregation in swine with pulmonary hypertension. ( Kazama, M; Kobayashi, K; Miyajima, Y; Tajimi, K; Tanaka, H, 2000) |
| "We conclude that milrinone is effective in the management of pulmonary hypertension following CPB in children who underwent TOF repair." | 3.70 | Effect of milrinone on postbypass pulmonary hypertension in children after tetralogy of Fallot repair. ( Chow, LH; Chu, CC; Lee, TY; Lin, SM; New, SH; Ting, CK; Tsai, SK; Tsou, MY, 2000) |
| "Milrinone and 6-bromo-8(methylamino)imidazo[1,2a]pyrazine-2-carbonitrile [SCA40; phosphodiesterase (PDE) III inhibitors], zaprinast (PDE V inhibitor), and 3-isobutyl-1-methyl xanthine (IBMX; nonselective PDE inhibitor) were examined on main pulmonary arteries from control rats and rats exposed to hypoxia (10% O2; 1 or 4 weeks) to induce pulmonary hypertension." | 3.70 | Phosphodiesterase III and V inhibitors on pulmonary artery from pulmonary hypertensive rats: differences between early and established pulmonary hypertension. ( Jeffery, TK; Wanstall, JC, 1998) |
| "In the setting of monocrotaline pyrrole-induced recipient pulmonary hypertension, milrinone was associated with significant improvements in pulmonary vascular impedance, right ventricular function, and transpulmonary efficiency." | 3.70 | Hemodynamic and inotropic effects of milrinone after heart transplantation in the setting of recipient pulmonary hypertension. ( Bittner, HB; Chen, EP; Davis, RD; Van Trigt, P, 1998) |
| "We studied the effects of milrinone on serotonin-induced pulmonary hypertension and bronchoconstriction in dogs." | 3.70 | Milrinone attenuates serotonin-induced pulmonary hypertension and bronchoconstriction in dogs. ( Hashiba, E; Hashimoto, Y; Hirota, K; Kudo, T; Matsuki, A; Sato, T; Yoshioka, H, 2000) |
| "This investigation demonstrates the well-known hemodynamic and inotropic effects of milrinone which, in the setting of monocrotaline pyrrole-induced pulmonary hypertension, were also associated with significant increases in pulmonary blood flow and left ventricular filling." | 3.69 | Milrinone improves pulmonary hemodynamics and right ventricular function in chronic pulmonary hypertension. ( Bittner, HB; Chen, EP; Davis, RD; Van Trigt, P, 1997) |
| "Bolus milrinone consistently decreases PVR in patients with pulmonary hypertension secondary to severe heart failure." | 3.69 | Effect of bolus milrinone on hemodynamic variables and pulmonary vascular resistance in patients with severe left ventricular dysfunction: a rapid test for reversibility of pulmonary hypertension. ( Colucci, WS; Gauthier, DF; Givertz, MM; Hare, JM; Loh, E, 1996) |
| "This study was designed to examine the effects of both nitric oxide and milrinone on pulmonary hemodynamics and right ventricular function using a newly established model of monocrotaline pyrrole-induced chronic pulmonary hypertension." | 3.69 | Right ventricular failure--insights provided by a new model of chronic pulmonary hypertension. ( Bittner, HB; Chen, EP; Davis, RD; Van Trigt, P, 1997) |
| "To evaluate the effects of milrinone (MIL) on hemodynamics and lung water content, we used 10 mongrel dogs with pulmonary hypertension (PH)." | 3.68 | Effects of milrinone on lung water content in dogs with acute pulmonary hypertension. ( Kobayashi, K; Matsumoto, A; Tajimi, K; Tanaka, H, 1992) |
| "Milrinone may have a selective pulmonary vasodilatory effect only in dogs with pulmonary hypertension." | 3.68 | Effects of milrinone on pulmonary vasculature in normal dogs and in dogs with pulmonary hypertension. ( Kobayashi, K; Moritsune, O; Okada, K; Tajimi, K; Tanaka, H, 1991) |
| " The present study shows the effects of MIL on the pulmonary circulation in dogs with pulmonary hypertension due to autologous muscle-induced pulmonary embolism, and also demonstrates a comparison with those of dopamine and dobutamine." | 3.68 | Vasodilatory effects of milrinone on pulmonary vasculature in dogs with pulmonary hypertension due to pulmonary embolism: a comparison with those of dopamine and dobutamine. ( Kobayashi, K; Matsumoto, A; Tajimi, K; Tanaka, H, 1990) |
| "Iloprost was administered during weaning from cardiopulmonary bypass (CPB)." | 2.73 | Inhaled iloprost to control pulmonary artery hypertension in patients undergoing mitral valve surgery: a prospective, randomized-controlled trial. ( Autschbach, R; Buhre, W; de Waal, EE; Flier, S; Metzelder, S; Rex, S; Rossaint, R; Schaelte, G, 2008) |
| "Milrinone was associated with a higher incidence of sinus bradycardia (D = 2%, M = 13%; p < 0." | 2.70 | Comparison of the hemodynamic effects of milrinone with dobutamine in patients after cardiac surgery. ( Feneck, RO; Oduro-Dominah, A; Sherry, KM; Withington, PS, 2001) |
| "Severe hypotension, cardiac arrest, and death have been reported previously." | 1.46 | Pulmonary Hypertensive Crisis on Induction of Anesthesia. ( Hilmi, I; Marquez, JM; Schisler, T; Subramaniam, K, 2017) |
| " Our aim was to compare acute dose-response hemodynamic effects of inodilators dobutamine (DOB), milrinone (MIL), and levosimendan (LEV) in chronic experimental PH." | 1.46 | Dose-Response Head-to-Head Comparison of Inodilators Dobutamine, Milrinone, and Levosimendan in Chronic Experimental Pulmonary Hypertension. ( Alaa, M; Leite, S; Leite-Moreira, AF; Lopes, L; Lourenço, AP; Oliveira-Pinto, J; Tavares-Silva, M, 2017) |
| "We report a 14-month-old child with persistent truncus arteriosus and crossed pulmonary arteries." | 1.43 | Crossed Pulmonary Arteries in a Patient With Persistent Truncus Arteriosus. ( Airan, B; Gulati, GS; Gupta, SK; Rajashekar, P; Talwar, S, 2016) |
| "Milrinone use was associated with an improvement in systolic and diastolic function in the RV, corresponding to an improvement in clinical status." | 1.38 | Use of milrinone to treat cardiac dysfunction in infants with pulmonary hypertension secondary to congenital diaphragmatic hernia: a review of six patients. ( Patel, N, 2012) |
| "Secondary pulmonary hypertension is a frequent condition after heart valve surgery." | 1.36 | Combined usage of inhaled and intravenous milrinone in pulmonary hypertension after heart valve surgery. ( Bulat, C; Carev, M; Husedzinović, I; Jercić, A; Karanović, N; Letica, D; Lojpur, M; Marovih, Z; Nenadić, D, 2010) |
| "Pulmonary hypertension was present in all groups following CPB." | 1.35 | Treating pulmonary hypertension post cardiopulmonary bypass in pigs: milrinone vs. sildenafil analog. ( Beaver, T; Kirby, DS; Klodell, C; Lobato, EB; Muehlschlegel, JD; Sidi, A; Urdaneta, F, 2008) |
| "He presented with an acute respiratory distress syndrome, a severe pulmonary hypertension was treated initially with mechanical ventilation and nitric oxide." | 1.35 | [Extracorporeal membranous oxygenation in severe infant pertussis: a case report]. ( Charpentier, A; Couchot, E; Ghez, O; Paut, O; Ughetto, F, 2009) |
| "Pretreatment with milrinone markedly enhanced relaxation to prostacyclin and iloprost in PPHN PA, similar to relaxation in control PA." | 1.35 | Milrinone enhances relaxation to prostacyclin and iloprost in pulmonary arteries isolated from lambs with persistent pulmonary hypertension of the newborn. ( Chen, B; Farrow, KN; Gugino, SF; Kumar, VH; Lakshminrusimha, S; Porta, NF; Russell, JA; Steinhorn, RH, 2009) |
| "Most patients with congestive heart failure (CHF) develop pulmonary venous hypertension, but right ventricular afterload is frequently further elevated by increased pulmonary vascular resistance." | 1.34 | Inhalation of the phosphodiesterase-3 inhibitor milrinone attenuates pulmonary hypertension in a rat model of congestive heart failure. ( Habbazettl, H; Hentschel, T; Koster, A; Kuebler, WM; Kuppe, H; Riad, A; Tschope, C; Weimann, J; Yin, N, 2007) |
| "Milrinone is a promising adjunctive therapy because of its pulmonary vasodilator properties and cardiotropic effects." | 1.33 | Milrinone improves oxygenation in neonates with severe persistent pulmonary hypertension of the newborn. ( Laique, F; McNamara, PJ; Muang-In, S; Whyte, HE, 2006) |
| "Pulmonary hypertension was induced with a continuous infusion of the thromboxane analogue, U46619." | 1.33 | Treatment with phosphodiesterase inhibitors type III and V: milrinone and sildenafil is an effective combination during thromboxane-induced acute pulmonary hypertension. ( Beaver, T; Kirby, DS; Klodell, C; Lobato, EB; Muehlschlegel, J; Sidi, A, 2006) |
| "A 65-year-old female with mitral regurgitation was scheduled for the mitral valve surgery." | 1.32 | [The use of milrinone in a patient with mitral regurgitation and severe pulmonary hypertension: a case report]. ( Arisaka, H; Katori, N; Tagawa, M; Takeda, J; Yamada, T; Yamamoto, S, 2003) |
| "In milrinone-treated lambs, nitric oxide decreased pulmonary vascular resistance by 26." | 1.32 | Phosphodiesterase-3 inhibition prevents the increase in pulmonary vascular resistance following inhaled nitric oxide withdrawal in lambs. ( Bekker, JM; Black, SM; Fineman, JR; Johengen, MJ; Oishi, P; Ovadia, B; Sanchez, LS; Thelitz, S, 2004) |
| "1% when administered intravenously at 30 microg/kg to the chronically hypoxic rats and had an apparent oral bioavailability of about 19." | 1.31 | 4-(3-Chloro-4-methoxybenzyl)aminophthalazines: synthesis and inhibitory activity toward phosphodiesterase 5. ( Adachi, H; Ishibashi, K; Ishihara, H; Kabasawa, Y; Kakiki, M; Kodama, K; Matsukura, M; Miyazaki, K; Nishino, M; Ozaki, H; Takase, Y; Watanabe, N, 2000) |
| "Pulmonary hypertension in patients with congestive heart failure (CHF) is a risk factor for increased mortality after orthotopic cardiac transplantation." | 1.30 | The use of milrinone in pre-transplant assessment of patients with congestive heart failure and pulmonary hypertension. ( Abel, JG; Carere, RG; Cook, RC; D'yachkova, Y; Ignaszewski, AP; Pamboukian, SV; Webb, JG, 1999) |
| "Milrinone is a phosphodiesterase inhibitor that has vasorelaxant activity." | 1.29 | [Acute effect of milrinone on pulmonary hemodynamics in patients with hypoxic pulmonary hypertension]. ( Chen, W; Cheng, D; Jiang, J, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (12.87) | 18.2507 |
| 2000's | 40 (39.60) | 29.6817 |
| 2010's | 34 (33.66) | 24.3611 |
| 2020's | 14 (13.86) | 2.80 |
| Authors | Studies |
|---|---|
| Watanabe, N | 1 |
| Adachi, H | 1 |
| Takase, Y | 1 |
| Ozaki, H | 1 |
| Matsukura, M | 1 |
| Miyazaki, K | 1 |
| Ishibashi, K | 1 |
| Ishihara, H | 1 |
| Kodama, K | 1 |
| Nishino, M | 1 |
| Kakiki, M | 1 |
| Kabasawa, Y | 1 |
| Imam, SS | 1 |
| El-Farrash, RA | 1 |
| Taha, AS | 1 |
| Saleh, GA | 1 |
| Elmi-Sarabi, M | 5 |
| Jarry, S | 3 |
| Couture, EJ | 1 |
| Haddad, F | 3 |
| Cogan, J | 1 |
| Sweatt, AJ | 1 |
| Rousseau-Saine, N | 1 |
| Beaubien-Souligny, W | 1 |
| Fortier, A | 3 |
| Denault, AY | 10 |
| El-Khuffash, A | 3 |
| McNamara, PJ | 7 |
| Breatnach, C | 3 |
| Bussmann, N | 3 |
| Smith, A | 3 |
| Feeney, O | 3 |
| Tully, E | 3 |
| Griffin, J | 3 |
| de Boode, WP | 3 |
| Cleary, B | 3 |
| Franklin, O | 5 |
| Dempsey, E | 3 |
| Couture, E | 2 |
| Saade, E | 2 |
| Calderone, A | 2 |
| Potes, C | 2 |
| Denault, A | 2 |
| Choobdar, FA | 1 |
| Shahhosseini, P | 1 |
| Vahedi, Z | 1 |
| Khosravi, N | 1 |
| Khalesi, N | 1 |
| Ghassemzadeh, M | 1 |
| Murray-Torres, RM | 1 |
| Chilson, K | 1 |
| Sharma, A | 1 |
| Nguyen, AQ | 2 |
| Théoret, Y | 4 |
| Perrault, LP | 7 |
| Varin, F | 5 |
| El-Ghandour, M | 1 |
| Hammad, B | 1 |
| Ghanem, M | 1 |
| Antonios, MAM | 1 |
| Mandell, E | 1 |
| Kinsella, JP | 1 |
| Abman, SH | 1 |
| Patel, J | 1 |
| Patel, K | 1 |
| Garg, P | 1 |
| Patel, S | 1 |
| Magoon, R | 1 |
| Kohli, JK | 1 |
| Kashav, R | 1 |
| Coleman, RD | 1 |
| Chartan, CA | 1 |
| Mourani, PM | 1 |
| Vogel, DJ | 1 |
| Brame, A | 1 |
| Hanks, F | 1 |
| Remmington, C | 1 |
| Chung, N | 1 |
| Camporota, L | 1 |
| Theodoraki, K | 1 |
| Thanopoulos, A | 1 |
| Rellia, P | 1 |
| Leontiadis, E | 1 |
| Zarkalis, D | 1 |
| Perreas, K | 1 |
| Antoniou, T | 1 |
| Gavra, P | 4 |
| Laflamme, M | 2 |
| Tavares-Silva, M | 1 |
| Alaa, M | 1 |
| Leite, S | 1 |
| Oliveira-Pinto, J | 1 |
| Lopes, L | 1 |
| Leite-Moreira, AF | 1 |
| Lourenço, AP | 1 |
| Ghadimi, K | 1 |
| Cappiello, JL | 1 |
| Kumar, VHS | 1 |
| Dadiz, R | 1 |
| Koumoundouros, J | 1 |
| Guilford, S | 1 |
| Lakshminrusimha, S | 5 |
| Eskandr, AM | 1 |
| Metwally, AA | 1 |
| Abu Elkassem, MS | 1 |
| Sadik, SA | 1 |
| Elmiligy, AE | 1 |
| Mourad, M | 1 |
| Hussein, L | 1 |
| Kundra, TS | 1 |
| Prabhakar, V | 1 |
| Kaur, P | 1 |
| Manjunatha, N | 1 |
| Gandham, R | 1 |
| Elhassan, A | 1 |
| Essandoh, M | 1 |
| Mears, M | 1 |
| Yang, M | 1 |
| Yoder, BA | 1 |
| Hötzel, A | 1 |
| Loop, T | 1 |
| Sharma, V | 1 |
| Tempe, DK | 1 |
| St-Pierre, P | 1 |
| Deschamps, A | 1 |
| Cartier, R | 1 |
| Basmadjian, AJ | 1 |
| Sakimura, S | 1 |
| Yoshino, J | 1 |
| Izumi, K | 1 |
| Jimi, N | 1 |
| Sumiyoshi, R | 1 |
| Mizuno, K | 1 |
| Steinhorn, RH | 3 |
| Litalien, C | 1 |
| James, AT | 2 |
| Bee, C | 1 |
| Corcoran, JD | 2 |
| El-Khuffash, AF | 2 |
| Carrier, M | 1 |
| Talwar, S | 1 |
| Rajashekar, P | 1 |
| Gupta, SK | 1 |
| Gulati, GS | 1 |
| Airan, B | 1 |
| Schisler, T | 1 |
| Marquez, JM | 1 |
| Hilmi, I | 1 |
| Subramaniam, K | 1 |
| Mishra, A | 1 |
| Kumar, B | 1 |
| Dutta, V | 1 |
| Arya, VK | 1 |
| Mishra, AK | 1 |
| Bussières, JS | 1 |
| Arellano, R | 1 |
| Finegan, B | 1 |
| Nguyen, AQN | 1 |
| Levesque, S | 1 |
| Shi, Y | 1 |
| Tardif, JC | 2 |
| Lambert, J | 3 |
| Bednarczyk, J | 1 |
| Strumpher, J | 1 |
| Jacobsohn, E | 1 |
| Urdaneta, F | 3 |
| Lobato, EB | 4 |
| Beaver, T | 3 |
| Muehlschlegel, JD | 1 |
| Kirby, DS | 3 |
| Klodell, C | 2 |
| Sidi, A | 2 |
| Cai, J | 1 |
| Su, Z | 1 |
| Shi, Z | 1 |
| Zhou, Y | 1 |
| Xu, Z | 2 |
| Liu, J | 1 |
| Chen, L | 1 |
| Yu, X | 1 |
| Ding, W | 1 |
| Yang, Y | 1 |
| Porta, NF | 1 |
| Farrow, KN | 1 |
| Chen, B | 1 |
| Gugino, SF | 1 |
| Kumar, VH | 3 |
| Russell, JA | 1 |
| Couchot, E | 1 |
| Paut, O | 1 |
| Ghez, O | 1 |
| Charpentier, A | 1 |
| Ughetto, F | 1 |
| Zhu, S | 1 |
| White, RE | 1 |
| Barman, SA | 1 |
| Wang, H | 2 |
| Gong, M | 1 |
| Zhou, B | 1 |
| Dai, A | 1 |
| Botha, P | 1 |
| Parry, G | 1 |
| Dark, JH | 1 |
| Macgowan, GA | 1 |
| Talwar, A | 1 |
| Sarkar, P | 1 |
| Rosen, MJ | 1 |
| Singh, R | 1 |
| Choudhury, M | 1 |
| Saxena, A | 1 |
| Kapoor, PM | 1 |
| Juneja, R | 1 |
| Kiran, U | 1 |
| Kim, JS | 1 |
| Nam, MH | 1 |
| Do, YS | 1 |
| Lee, CJ | 1 |
| Kim, CS | 1 |
| Sim, WS | 1 |
| Park, KB | 1 |
| Lee, SH | 1 |
| Han, JS | 1 |
| Shin, BS | 1 |
| Kim, HY | 1 |
| Swartz, DD | 2 |
| Rashid, N | 2 |
| Ma, C | 1 |
| Ryan, RM | 2 |
| Morin, FC | 2 |
| Huang, J | 1 |
| Bouvette, MJ | 1 |
| Zhou, J | 1 |
| Carev, M | 1 |
| Bulat, C | 1 |
| Karanović, N | 1 |
| Lojpur, M | 1 |
| Jercić, A | 1 |
| Nenadić, D | 1 |
| Marovih, Z | 1 |
| Husedzinović, I | 1 |
| Letica, D | 1 |
| Chai, TS | 1 |
| Charchaflieh, J | 1 |
| Svyatets, M | 1 |
| Patel, N | 1 |
| Giaccone, A | 1 |
| Kirpalani, H | 1 |
| Shivananda, SP | 1 |
| Sahni, M | 1 |
| Freeman, D | 1 |
| Taddio, A | 1 |
| Kaneko, T | 1 |
| Yamada, T | 1 |
| Katori, N | 1 |
| Tagawa, M | 1 |
| Yamamoto, S | 1 |
| Arisaka, H | 1 |
| Takeda, J | 1 |
| Ravishankar, C | 1 |
| Tabbutt, S | 1 |
| Wernovsky, G | 1 |
| Matot, I | 1 |
| Gozal, Y | 1 |
| Khazin, V | 1 |
| Kaufman, Y | 1 |
| Zabeeda, D | 1 |
| Medalion, B | 1 |
| Sasson, L | 1 |
| Schachner, A | 1 |
| Ezri, T | 1 |
| Gelvez, J | 1 |
| Fakioglu, H | 1 |
| Olarte, JL | 1 |
| Soliz, A | 1 |
| Totapally, BR | 1 |
| Torbati, D | 1 |
| Thelitz, S | 1 |
| Oishi, P | 1 |
| Sanchez, LS | 1 |
| Bekker, JM | 1 |
| Ovadia, B | 1 |
| Johengen, MJ | 1 |
| Black, SM | 1 |
| Fineman, JR | 1 |
| Willert, JL | 1 |
| Naik, B | 1 |
| Trachte, AL | 1 |
| Hess, PJ | 1 |
| Klodell, CT | 1 |
| Martin, TD | 1 |
| Staples, ED | 1 |
| Beaver, TM | 1 |
| Raja, SG | 1 |
| Tsai, BM | 1 |
| Wang, M | 1 |
| Pitcher, JM | 1 |
| Kher, A | 1 |
| Crisostomo, P | 1 |
| Meldrum, DR | 1 |
| Sablotzki, A | 1 |
| Starzmann, W | 1 |
| Scheubel, R | 1 |
| Grond, S | 1 |
| Czeslick, EG | 1 |
| Muehlschlegel, J | 1 |
| Kissoon, N | 1 |
| Laique, F | 1 |
| Muang-In, S | 1 |
| Whyte, HE | 1 |
| Wynn, KA | 1 |
| Hentschel, T | 1 |
| Yin, N | 1 |
| Riad, A | 1 |
| Habbazettl, H | 1 |
| Weimann, J | 1 |
| Koster, A | 1 |
| Tschope, C | 1 |
| Kuppe, H | 1 |
| Kuebler, WM | 1 |
| Lamarche, Y | 2 |
| Couture, P | 1 |
| Oztekin, I | 1 |
| Yazici, S | 1 |
| Oztekin, DS | 1 |
| Goksel, O | 1 |
| Issever, H | 1 |
| Canik, S | 1 |
| Maltais, S | 1 |
| Tétreault, K | 1 |
| Rex, S | 1 |
| Schaelte, G | 1 |
| Metzelder, S | 1 |
| Flier, S | 1 |
| de Waal, EE | 1 |
| Autschbach, R | 1 |
| Rossaint, R | 1 |
| Buhre, W | 1 |
| Egawa, J | 1 |
| Inoue, S | 1 |
| Shinjo, T | 1 |
| Furuya, H | 1 |
| Buckley, MS | 1 |
| Feldman, JP | 1 |
| Cheng, D | 1 |
| Chen, W | 1 |
| Jiang, J | 1 |
| Feneck, RO | 2 |
| Givertz, MM | 1 |
| Hare, JM | 1 |
| Loh, E | 1 |
| Gauthier, DF | 1 |
| Colucci, WS | 1 |
| Chen, EP | 4 |
| Bittner, HB | 4 |
| Davis, RD | 4 |
| Van Trigt, P | 4 |
| Craig, DM | 1 |
| Jeffery, TK | 1 |
| Wanstall, JC | 1 |
| Pamboukian, SV | 1 |
| Carere, RG | 1 |
| Webb, JG | 1 |
| Cook, RC | 1 |
| D'yachkova, Y | 1 |
| Abel, JG | 1 |
| Ignaszewski, AP | 1 |
| Solina, A | 1 |
| Papp, D | 1 |
| Ginsberg, S | 1 |
| Krause, T | 1 |
| Grubb, W | 1 |
| Scholz, P | 1 |
| Pena, LL | 1 |
| Cody, R | 1 |
| Hashiba, E | 1 |
| Hirota, K | 1 |
| Yoshioka, H | 1 |
| Hashimoto, Y | 1 |
| Kudo, T | 1 |
| Sato, T | 1 |
| Matsuki, A | 1 |
| Deb, B | 1 |
| Bradford, K | 1 |
| Pearl, RG | 1 |
| Chu, CC | 1 |
| Lin, SM | 1 |
| New, SH | 1 |
| Ting, CK | 1 |
| Chow, LH | 1 |
| Tsou, MY | 1 |
| Tsai, SK | 1 |
| Lee, TY | 1 |
| Tanaka, H | 4 |
| Tajimi, K | 4 |
| Miyajima, Y | 1 |
| Kazama, M | 1 |
| Kobayashi, K | 4 |
| Sherry, KM | 1 |
| Withington, PS | 1 |
| Oduro-Dominah, A | 1 |
| Stobierska-Dzierzek, B | 1 |
| Awad, H | 1 |
| Michler, RE | 1 |
| Haraldsson s, A | 1 |
| Kieler-Jensen, N | 1 |
| Ricksten, SE | 1 |
| Ricksten, S | 1 |
| Matsumoto, A | 2 |
| Wu, PF | 1 |
| Moritsune, O | 1 |
| Okada, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Milrinone Versus Sildenafil in Treatment of PPHN in Neonates[NCT04391478] | Phase 1 | 40 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
| Effectiveness of Nebulized Magnesium Sulfate Combined With Sildenafil Citrate in Persistent Pulmonary Hypertension of Newborn[NCT04898114] | Phase 1/Phase 2 | 40 participants (Anticipated) | Interventional | 2021-06-02 | Recruiting | ||
| Levosimendan Administration in High Risk Cardiac Surgery Patients With Pulmonary Hypertension[NCT04599816] | 45 participants (Actual) | Interventional | 2020-10-17 | Completed | |||
| Comparison of Intravenous Levosimendan and Inhalational Milrinone in High Risk Cardiac Patients With Pulmonary Hypertension[NCT04718350] | 40 participants (Anticipated) | Interventional | 2021-01-27 | Recruiting | |||
| Paceport Swan-Ganz Data Collection Study[NCT04782154] | 136 participants (Actual) | Observational | 2021-08-09 | Completed | |||
| Validation of Cerebral Non-invasive Monitoring and Prediction of Post-operative Delirium and Outcomes: A Prospective Observational Study[NCT04643834] | 151 participants (Anticipated) | Observational | 2019-11-21 | Recruiting | |||
| Early Identification and Prediction of Right Ventricular Dysfunction and Failure in Critically Ill Patients: An Observational Non-Interventional Cohort Study[NCT04092855] | 112 participants (Anticipated) | Observational | 2018-12-10 | Recruiting | |||
| 2- Inhaled Milrinone Prevents the Increase in Pulmonary Artery Pressure After CPB[NCT00819377] | Phase 2 | 124 participants (Anticipated) | Interventional | 2009-02-28 | Completed | ||
| Inhaled Milrinone and Epoprostenol for the Prevention of Difficult Cardiac Pulmonary Bypass Separation: A Randomized, Double-blind, Controlled Trial[NCT05450328] | Phase 2 | 141 participants (Anticipated) | Interventional | 2022-09-01 | Not yet recruiting | ||
| Comparative Study Between Inhaled and Intravenous Milrinone in Patients With Severe Pulmonary Hypertension Undergoing Cardiac Surgery[NCT04484675] | Phase 4 | 38 participants (Anticipated) | Interventional | 2022-01-20 | Recruiting | ||
| Right Ventricular Function After Withdrawal of Phosphodiesterase-5 Inhibitors in Left Ventricular Assist Device Recipients[NCT04117659] | 32 participants (Actual) | Interventional | 2019-10-15 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 reviews available for milrinone and Hypertension, Pulmonary
| Article | Year |
|---|---|
Persistent pulmonary hypertension of the newborn.
Topics: Bosentan; Epoprostenol; Humans; Hypertension, Pulmonary; Hypoxia; Infant; Infant, Newborn; Infant, P | 2021 |
Intensive care management of right ventricular failure and pulmonary hypertension crises.
Topics: Biomarkers; Capnography; Central Venous Pressure; Critical Care; Echocardiography; Epinephrine; Epop | 2021 |
[Anaesthesia in Patients with Pulmonary Hypertension].
Topics: Anesthesia, General; Anesthetics; Humans; Hypertension, Pulmonary; Milrinone; Nitric Oxide; Sildenaf | 2019 |
Pulmonary arterial hypertension in human immunodeficiency virus infection.
Topics: Anti-Retroviral Agents; Causality; Comorbidity; Dobutamine; Drug Therapy, Combination; Endothelin Re | 2009 |
Critical care in cardiovascular medicine.
Topics: Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Child; Critical Care; Dye Dilu | 2003 |
Oral sildenafil reduces pulmonary hypertension after cardiac surgery.
Topics: Adult; Aged; Cardiac Surgical Procedures; Drug Evaluation; Drug Resistance; Female; Hemodynamics; Hu | 2005 |
Inhaled milrinone: a new alternative in cardiac surgery?
Topics: Administration, Inhalation; Animals; Endpoint Determination; Heart Function Tests; Humans; Hypertens | 2006 |
Milrinone and postoperative pulmonary hypertension.
Topics: Animals; Cardiac Surgical Procedures; Cardiotonic Agents; Humans; Hypertension, Pulmonary; Milrinone | 1993 |
The evolving management of acute right-sided heart failure in cardiac transplant recipients.
Topics: Alprostadil; Animals; Cardiotonic Agents; Epoprostenol; Heart Transplantation; Heart-Assist Devices; | 2001 |
[The pulmonary vasodilatory effect of inhaled prostacyclin and milrinone in heart].
Topics: Acute Disease; Administration, Inhalation; Cardiac Surgical Procedures; Cyclic AMP; Drug Synergism; | 2001 |
21 trials available for milrinone and Hypertension, Pulmonary
| Article | Year |
|---|---|
Milrinone Versus Sildenafil in Treatment of Neonatal Persistent Pulmonary Hypertension: A Randomized Control Trial.
Topics: Humans; Hypertension, Pulmonary; Infant, Newborn; Milrinone; Nitric Oxide; Persistent Fetal Circulat | 2022 |
The use of milrinone in neonates with persistent pulmonary hypertension of the newborn - a randomised controlled trial pilot study (MINT 1).
Topics: Administration, Inhalation; Humans; Hypertension, Pulmonary; Infant, Newborn; Milrinone; Nitric Oxid | 2023 |
The use of milrinone in neonates with persistent pulmonary hypertension of the newborn - a randomised controlled trial pilot study (MINT 1).
Topics: Administration, Inhalation; Humans; Hypertension, Pulmonary; Infant, Newborn; Milrinone; Nitric Oxid | 2023 |
The use of milrinone in neonates with persistent pulmonary hypertension of the newborn - a randomised controlled trial pilot study (MINT 1).
Topics: Administration, Inhalation; Humans; Hypertension, Pulmonary; Infant, Newborn; Milrinone; Nitric Oxid | 2023 |
The use of milrinone in neonates with persistent pulmonary hypertension of the newborn - a randomised controlled trial pilot study (MINT 1).
Topics: Administration, Inhalation; Humans; Hypertension, Pulmonary; Infant, Newborn; Milrinone; Nitric Oxid | 2023 |
The use of milrinone in neonates with persistent pulmonary hypertension of the newborn - a randomised controlled trial pilot study (MINT 1).
Topics: Administration, Inhalation; Humans; Hypertension, Pulmonary; Infant, Newborn; Milrinone; Nitric Oxid | 2023 |
The use of milrinone in neonates with persistent pulmonary hypertension of the newborn - a randomised controlled trial pilot study (MINT 1).
Topics: Administration, Inhalation; Humans; Hypertension, Pulmonary; Infant, Newborn; Milrinone; Nitric Oxid | 2023 |
The use of milrinone in neonates with persistent pulmonary hypertension of the newborn - a randomised controlled trial pilot study (MINT 1).
Topics: Administration, Inhalation; Humans; Hypertension, Pulmonary; Infant, Newborn; Milrinone; Nitric Oxid | 2023 |
The use of milrinone in neonates with persistent pulmonary hypertension of the newborn - a randomised controlled trial pilot study (MINT 1).
Topics: Administration, Inhalation; Humans; Hypertension, Pulmonary; Infant, Newborn; Milrinone; Nitric Oxid | 2023 |
The use of milrinone in neonates with persistent pulmonary hypertension of the newborn - a randomised controlled trial pilot study (MINT 1).
Topics: Administration, Inhalation; Humans; Hypertension, Pulmonary; Infant, Newborn; Milrinone; Nitric Oxid | 2023 |
Comparison of the efficacy of inhaled versus infused milrinone in the management of persistent pulmonary hypertension of the newborn in resource-limited settings: A randomized clinical trial.
Topics: Administration, Inhalation; Humans; Hypertension, Pulmonary; Infant, Newborn; Milrinone; Nitric Oxid | 2023 |
Inhaled milrinone in cardiac surgical patients: a pilot randomized controlled trial of jet vs. mesh nebulization.
Topics: Administration, Inhalation; Aged; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Female; Hemod | 2020 |
Efficacy of Milrinone Plus Sildenafil in the Treatment of Neonates with Persistent Pulmonary Hypertension in Resource-Limited Settings: Results of a Randomized, Double-Blind Trial.
Topics: Double-Blind Method; Female; Humans; Hypertension, Pulmonary; Infant, Newborn; Male; Milrinone; Sild | 2020 |
Dobutamine and Nitroglycerin Versus Milrinone for Perioperative Management of Pulmonary Hypertension in Mitral Valve Surgery. A Randomized Controlled Study.
Topics: Adolescent; Adrenergic beta-1 Receptor Agonists; Adult; Dobutamine; Dose-Response Relationship, Drug | 2018 |
The Effect of Inhaled Milrinone Versus Inhaled Levosimendan in Pulmonary Hypertension Patients Undergoing Mitral Valve Surgery - A Pilot Randomized Double-Blind Study.
Topics: Administration, Inhalation; Adult; Blood Pressure; Cardiotonic Agents; Dose-Response Relationship, D | 2018 |
Comparative Effect of Levosimendan and Milrinone in Cardiac Surgery Patients With Pulmonary Hypertension and Left Ventricular Dysfunction.
Topics: Adult; Aortic Valve; Arterial Pressure; Drug Administration Schedule; Drug Therapy, Combination; Fem | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
A multicentre randomized-controlled trial of inhaled milrinone in high-risk cardiac surgical patients.
Topics: Administration, Inhalation; Aged; Cardiac Output; Cardiac Surgical Procedures; Catheterization, Swan | 2016 |
Nitric oxide in conjunction with milrinone better stabilized pulmonary hemodynamics after Fontan procedure.
Topics: Administration, Inhalation; Blood Pressure; Child; Child, Preschool; Drug Therapy, Combination; Fema | 2008 |
Comparison of inhaled and intravenous milrinone in patients with pulmonary hypertension undergoing mitral valve surgery.
Topics: Administration, Inhalation; Adult; Analysis of Variance; Cardiac Output; Cardiopulmonary Bypass; Fem | 2009 |
Acute hemodynamic effects of intravenous sildenafil citrate in congestive heart failure: comparison of phosphodiesterase type-3 and -5 inhibition.
Topics: Adult; Blood Pressure; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodieste | 2009 |
Inhaled nitroglycerin versus inhaled milrinone in children with congenital heart disease suffering from pulmonary artery hypertension.
Topics: Administration, Inhalation; Child; Child, Preschool; Female; Heart Defects, Congenital; Humans; Hype | 2010 |
Pharmacology of milrinone in neonates with persistent pulmonary hypertension of the newborn and suboptimal response to inhaled nitric oxide.
Topics: Administration, Inhalation; Bronchodilator Agents; Cardiac Output; Echocardiography; Half-Life; Huma | 2013 |
Milrinone and nitric oxide: combined effect on pulmonary artery pressures after cardiopulmonary bypass in children.
Topics: Blood Pressure; Bronchodilator Agents; Carbon Dioxide; Cardiopulmonary Bypass; Cardiotonic Agents; C | 2004 |
Selective pulmonary vasodilation with inhaled aerosolized milrinone in heart transplant candidates.
Topics: Adult; Aerosols; Blood Volume; Cardiomyopathy, Dilated; Extravascular Lung Water; Heart Transplantat | 2005 |
Effects of low-dose milrinone on weaning from cardiopulmonary bypass and after in patients with mitral stenosis and pulmonary hypertension.
Topics: Adult; Cardiopulmonary Bypass; Female; Heart Valve Prosthesis Implantation; Humans; Hypertension, Pu | 2007 |
Inhaled iloprost to control pulmonary artery hypertension in patients undergoing mitral valve surgery: a prospective, randomized-controlled trial.
Topics: Administration, Inhalation; Aged; Cardiac Output, Low; Cardiopulmonary Bypass; Catheterization, Swan | 2008 |
A comparison of inhaled nitric oxide and milrinone for the treatment of pulmonary hypertension in adult cardiac surgery patients.
Topics: Administration, Inhalation; Aged; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Heart Rate; H | 2000 |
Comparison of the hemodynamic effects of milrinone with dobutamine in patients after cardiac surgery.
Topics: Adrenergic beta-Agonists; Blood Gas Analysis; Cardiac Output, Low; Cardiac Surgical Procedures; Dobu | 2001 |
The additive pulmonary vasodilatory effects of inhaled prostacyclin and inhaled milrinone in postcardiac surgical patients with pulmonary hypertension.
Topics: Administration, Inhalation; Aged; Antihypertensive Agents; Cardiac Surgical Procedures; Drug Synergi | 2001 |
70 other studies available for milrinone and Hypertension, Pulmonary
| Article | Year |
|---|---|
4-(3-Chloro-4-methoxybenzyl)aminophthalazines: synthesis and inhibitory activity toward phosphodiesterase 5.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Antihypertensive Agents; Biological Availability; Bloo | 2000 |
Pulmonary Vasodilator Response of Combined Inhaled Epoprostenol and Inhaled Milrinone in Cardiac Surgical Patients.
Topics: Administration, Inhalation; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Epoprostenol; Human | 2023 |
Inhaled Epoprostenol and Milrinone Effect on Right Ventricular Pressure Waveform Monitoring.
Topics: Adult; Cohort Studies; Epoprostenol; Humans; Hypertension, Pulmonary; Milrinone; Prospective Studies | 2023 |
Inhaled Epoprostenol and Milrinone Effect on Right Ventricular Pressure Waveform Monitoring.
Topics: Adult; Cohort Studies; Epoprostenol; Humans; Hypertension, Pulmonary; Milrinone; Prospective Studies | 2023 |
Inhaled Epoprostenol and Milrinone Effect on Right Ventricular Pressure Waveform Monitoring.
Topics: Adult; Cohort Studies; Epoprostenol; Humans; Hypertension, Pulmonary; Milrinone; Prospective Studies | 2023 |
Inhaled Epoprostenol and Milrinone Effect on Right Ventricular Pressure Waveform Monitoring.
Topics: Adult; Cohort Studies; Epoprostenol; Humans; Hypertension, Pulmonary; Milrinone; Prospective Studies | 2023 |
Anesthetic management of children with medically refractory pulmonary hypertension undergoing surgical Potts shunt.
Topics: Anesthesia, General; Anesthetics; Child; Dobutamine; Epinephrine; Humans; Hypertension, Pulmonary; I | 2024 |
Inhaled versus intravenous milrinone in mitral stenosis with pulmonary hypertension.
Topics: Administration, Inhalation; Administration, Intravenous; Adult; Antihypertensive Agents; Cardiopulmo | 2021 |
Inhaled milrinone for sick COVID-19 cohort: A pathophysiology driven hypothesis!
Topics: Cardiopulmonary Bypass; COVID-19; Humans; Hypertension, Pulmonary; Milrinone; SARS-CoV-2 | 2021 |
Improved oxygenation with inhaled milrinone in mechanically ventilated patients with severe COVID-19.
Topics: Administration, Inhalation; Aged; COVID-19; Female; Humans; Hypertension, Pulmonary; Male; Middle Ag | 2021 |
A retrospective comparison of inhaled milrinone and iloprost in post-bypass pulmonary hypertension.
Topics: Administration, Inhalation; Aged; Aged, 80 and over; Arterial Pressure; Cardiopulmonary Bypass; Dose | 2017 |
A retrospective comparison of inhaled milrinone and iloprost in post-bypass pulmonary hypertension.
Topics: Administration, Inhalation; Aged; Aged, 80 and over; Arterial Pressure; Cardiopulmonary Bypass; Dose | 2017 |
A retrospective comparison of inhaled milrinone and iloprost in post-bypass pulmonary hypertension.
Topics: Administration, Inhalation; Aged; Aged, 80 and over; Arterial Pressure; Cardiopulmonary Bypass; Dose | 2017 |
A retrospective comparison of inhaled milrinone and iloprost in post-bypass pulmonary hypertension.
Topics: Administration, Inhalation; Aged; Aged, 80 and over; Arterial Pressure; Cardiopulmonary Bypass; Dose | 2017 |
Use of nebulized milrinone in cardiac surgery; Comparison of vibrating mesh and simple jet nebulizers.
Topics: Administration, Inhalation; Animals; Cardiopulmonary Bypass; Cardiotonic Agents; Endothelium, Vascul | 2017 |
Dose-Response Head-to-Head Comparison of Inodilators Dobutamine, Milrinone, and Levosimendan in Chronic Experimental Pulmonary Hypertension.
Topics: Animals; Calcium; Chronic Disease; Dobutamine; Dose-Response Relationship, Drug; Hemodynamics; Hydra | 2017 |
Pharmacokinetics and Pharmacodynamics of Nebulized and Intratracheal Milrinone in a Swine Model of Hypercapnia Pulmonary Hypertension.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hypercapnia; Hypertension | 2018 |
Intrapulmonary Milrinone for Cardiac Surgery Provides Insight Into Precision Delivery of Aerosolized Vasodilators.
Topics: Cardiac Surgical Procedures; Cardiotonic Agents; Hemodynamics; Humans; Hypertension, Pulmonary; Milr | 2018 |
Response to pulmonary vasodilators in infants with congenital diaphragmatic hernia.
Topics: Abnormalities, Multiple; Administration, Inhalation; Blood Gas Analysis; Extracorporeal Membrane Oxy | 2018 |
Inhaled Levosimendan for Pulmonary Hypertension Treatment During Cardiac Surgery: A Novel Application to Avoid Systemic Hypotension.
Topics: Double-Blind Method; Humans; Hypertension, Pulmonary; Hypotension; Milrinone; Mitral Valve; Pilot Pr | 2019 |
Inhaled Levosimendan for Pulmonary Hypertension Treatment During Cardiac Surgery: A Novel Application to Avoid Systemic Hypotension.
Topics: Double-Blind Method; Humans; Hypertension, Pulmonary; Hypotension; Milrinone; Mitral Valve; Pilot Pr | 2019 |
Inhaled Levosimendan for Pulmonary Hypertension Treatment During Cardiac Surgery: A Novel Application to Avoid Systemic Hypotension.
Topics: Double-Blind Method; Humans; Hypertension, Pulmonary; Hypotension; Milrinone; Mitral Valve; Pilot Pr | 2019 |
Inhaled Levosimendan for Pulmonary Hypertension Treatment During Cardiac Surgery: A Novel Application to Avoid Systemic Hypotension.
Topics: Double-Blind Method; Humans; Hypertension, Pulmonary; Hypotension; Milrinone; Mitral Valve; Pilot Pr | 2019 |
Is Milrinone Effective for Infants with Mild-to-Moderate Congenital Diaphragmatic Hernia?
Topics: Female; Hernias, Diaphragmatic, Congenital; Humans; Hypertension, Pulmonary; Infant, Newborn; Male; | 2020 |
The Effect of Inhaled Milrinone Versus Inhaled Levosimendan in Pulmonary Hypertension Patients Undergoing Mitral Valve Surgery.
Topics: Double-Blind Method; Humans; Hypertension, Pulmonary; Milrinone; Mitral Valve; Pilot Projects; Simen | 2019 |
Inhaled milrinone and epoprostenol in a patient with severe pulmonary hypertension, right ventricular failure, and reduced baseline brain saturation value from a left atrial myxoma.
Topics: Administration, Inhalation; Adult; Antihypertensive Agents; Brain Chemistry; Cardiac Surgical Proced | 2014 |
Inhaled milrinone and epoprostenol in a patient with severe pulmonary hypertension, right ventricular failure, and reduced baseline brain saturation value from a left atrial myxoma.
Topics: Administration, Inhalation; Adult; Antihypertensive Agents; Brain Chemistry; Cardiac Surgical Proced | 2014 |
Inhaled milrinone and epoprostenol in a patient with severe pulmonary hypertension, right ventricular failure, and reduced baseline brain saturation value from a left atrial myxoma.
Topics: Administration, Inhalation; Adult; Antihypertensive Agents; Brain Chemistry; Cardiac Surgical Proced | 2014 |
Inhaled milrinone and epoprostenol in a patient with severe pulmonary hypertension, right ventricular failure, and reduced baseline brain saturation value from a left atrial myxoma.
Topics: Administration, Inhalation; Adult; Antihypertensive Agents; Brain Chemistry; Cardiac Surgical Proced | 2014 |
Inhaled milrinone and epoprostenol in a patient with severe pulmonary hypertension, right ventricular failure, and reduced baseline brain saturation value from a left atrial myxoma.
Topics: Administration, Inhalation; Adult; Antihypertensive Agents; Brain Chemistry; Cardiac Surgical Proced | 2014 |
Inhaled milrinone and epoprostenol in a patient with severe pulmonary hypertension, right ventricular failure, and reduced baseline brain saturation value from a left atrial myxoma.
Topics: Administration, Inhalation; Adult; Antihypertensive Agents; Brain Chemistry; Cardiac Surgical Proced | 2014 |
Inhaled milrinone and epoprostenol in a patient with severe pulmonary hypertension, right ventricular failure, and reduced baseline brain saturation value from a left atrial myxoma.
Topics: Administration, Inhalation; Adult; Antihypertensive Agents; Brain Chemistry; Cardiac Surgical Proced | 2014 |
Inhaled milrinone and epoprostenol in a patient with severe pulmonary hypertension, right ventricular failure, and reduced baseline brain saturation value from a left atrial myxoma.
Topics: Administration, Inhalation; Adult; Antihypertensive Agents; Brain Chemistry; Cardiac Surgical Proced | 2014 |
Inhaled milrinone and epoprostenol in a patient with severe pulmonary hypertension, right ventricular failure, and reduced baseline brain saturation value from a left atrial myxoma.
Topics: Administration, Inhalation; Adult; Antihypertensive Agents; Brain Chemistry; Cardiac Surgical Proced | 2014 |
[Comparison of the effects of phosphodiesterase III inhibitors, milrinone and olprinone, in infant corrective cardiac surgery].
Topics: Cardiac Surgical Procedures; Female; Heart Septal Defects, Ventricular; Hemodynamics; Humans; Hypert | 2013 |
Diagnosis and treatment of pulmonary hypertension in infancy.
Topics: Bosentan; Bronchopulmonary Dysplasia; Hernia, Diaphragmatic; Humans; Hypertension, Pulmonary; Infant | 2013 |
A specific and sensitive HPLC-MS/MS micromethod for milrinone plasma levels determination after inhalation in cardiac patients.
Topics: Administration, Inhalation; Cardiopulmonary Bypass; Chemical Fractionation; Chromatography, High Pre | 2014 |
Treatment of premature infants with pulmonary hypertension and right ventricular dysfunction with milrinone: a case series.
Topics: Blood Pressure; Echocardiography; Female; Fetofetal Transfusion; Humans; Hypertension, Pulmonary; In | 2015 |
Preliminary experience with combined inhaled milrinone and prostacyclin in cardiac surgical patients with pulmonary hypertension.
Topics: Administration, Inhalation; Aged; Antihypertensive Agents; Cardiac Surgical Procedures; Case-Control | 2015 |
The effect of milrinone on right and left ventricular function when used as a rescue therapy for term infants with pulmonary hypertension.
Topics: Female; Humans; Hypertension, Pulmonary; Infant; Male; Milrinone; Phosphodiesterase 3 Inhibitors; Re | 2016 |
Crossed Pulmonary Arteries in a Patient With Persistent Truncus Arteriosus.
Topics: Abnormalities, Multiple; Anastomosis, Surgical; Cardiomegaly; Cardiopulmonary Bypass; Combined Modal | 2016 |
Pulmonary Hypertensive Crisis on Induction of Anesthesia.
Topics: Adrenergic alpha-Agonists; Anesthesia; Bronchodilator Agents; Calcium Chloride; Cardiopulmonary Resu | 2017 |
Inhaled milrinone for pulmonary hypertension in high-risk cardiac surgery: silver bullet or just part of a broader management strategy?
Topics: Administration, Inhalation; Cardiac Surgical Procedures; Humans; Hypertension, Pulmonary; Milrinone; | 2016 |
Treating pulmonary hypertension post cardiopulmonary bypass in pigs: milrinone vs. sildenafil analog.
Topics: Acute Disease; Animals; Blood Pressure; Cardiopulmonary Bypass; Hypertension, Pulmonary; Milrinone; | 2008 |
Milrinone enhances relaxation to prostacyclin and iloprost in pulmonary arteries isolated from lambs with persistent pulmonary hypertension of the newborn.
Topics: Animals; Animals, Newborn; Blotting, Western; Disease Models, Animal; Drug Interactions; Drug Therap | 2009 |
[Extracorporeal membranous oxygenation in severe infant pertussis: a case report].
Topics: Cardiotonic Agents; Critical Care; Extracorporeal Membrane Oxygenation; Humans; Hypertension, Pulmon | 2009 |
Role of phosphodiesterases in modulation of BKCa channels in hypertensive pulmonary arterial smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP; Disease Models, Animal; Hypertension, P | 2008 |
Efficacy of milrinone versus nitroglycerin in controlling pulmonary arterial hypertension induced by intravenous injections of absolute ethanol in anesthetized dogs.
Topics: Animals; Antihypertensive Agents; Dogs; Ethanol; Female; Hypertension, Pulmonary; Injections, Intrav | 2010 |
Prostacyclin and milrinone by aerosolization improve pulmonary hemodynamics in newborn lambs with experimental pulmonary hypertension.
Topics: Administration, Inhalation; Aerosols; Animals; Animals, Newborn; Antihypertensive Agents; Blood Pres | 2010 |
Simultaneous delivery of inhaled prostacyclin and milrinone through a double nebulizer system.
Topics: Drug Delivery Systems; Drug Therapy, Combination; Epoprostenol; Humans; Hypertension, Pulmonary; Mil | 2011 |
Combined usage of inhaled and intravenous milrinone in pulmonary hypertension after heart valve surgery.
Topics: Administration, Inhalation; Aortic Valve; Female; Heart Valve Prosthesis Implantation; Humans; Hyper | 2010 |
Pulmonary hypertension in a patient with subarachnoid hemorrhage.
Topics: Cardiotonic Agents; Coronary Angiography; Echocardiography; Embolization, Therapeutic; Humans; Hyper | 2011 |
Use of milrinone to treat cardiac dysfunction in infants with pulmonary hypertension secondary to congenital diaphragmatic hernia: a review of six patients.
Topics: Antihypertensive Agents; Arterial Pressure; Cardiotonic Agents; Diastole; Echocardiography, Doppler; | 2012 |
Judgment often impossible without randomized trials. Commentary on N. Patel: use of milrinone to treat cardiac dysfunction in infants with pulmonary hypertension secondary to congenital diaphragmatic hernia: a review of six patients (Neonatology 2012;102:
Topics: Antihypertensive Agents; Cardiotonic Agents; Familial Primary Pulmonary Hypertension; Female; Hernia | 2012 |
[Anesthetic management of hip joint fracture surgery in an elderly patient with giant pulmonary artery aneurysm].
Topics: Aged, 80 and over; Anesthesia, Spinal; Aneurysm; Female; Hip Fractures; Humans; Hypertension, Pulmon | 2012 |
Inodilators in nitric oxide resistant persistent pulmonary hypertension of the newborn.
Topics: Humans; Hypertension, Pulmonary; Milrinone; Phosphodiesterase 3 Inhibitors | 2013 |
[The use of milrinone in a patient with mitral regurgitation and severe pulmonary hypertension: a case report].
Topics: Aged; Female; Humans; Hypertension, Pulmonary; Milrinone; Mitral Valve; Mitral Valve Insufficiency; | 2003 |
Pulmonary responses to selective phosphodiesterase-5 and phosphodiesterase-3 inhibitors.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3',5'-Cyclic-AMP Phosphodiestera | 2004 |
Effect of aerosolized milrinone during drug-induced pulmonary hypertension in lambs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aerosols; Animals; Hemodynamics; | 2004 |
Phosphodiesterase-3 inhibition prevents the increase in pulmonary vascular resistance following inhaled nitric oxide withdrawal in lambs.
Topics: Administration, Inhalation; Animals; Cyclic AMP; Endothelium-Dependent Relaxing Factors; Hypertensio | 2004 |
Effects of a new phosphodiesterase enzyme type V inhibitor (UK 343-664) versus milrinone in a porcine model of acute pulmonary hypertension.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3',5'-Cyclic-GMP Phosphodiestera | 2004 |
Milrinone for pulmonary hypertension: additional benefits, concerns, and caution.
Topics: Humans; Hypertension, Pulmonary; Milrinone | 2005 |
Zaprinast attenuates hypoxic pulmonary artery injury and causes less aortic relaxation than milrinone.
Topics: Animals; Aorta; Aorta, Thoracic; Dose-Response Relationship, Drug; Drug Synergism; Hypertension, Pul | 2005 |
Treatment with phosphodiesterase inhibitors type III and V: milrinone and sildenafil is an effective combination during thromboxane-induced acute pulmonary hypertension.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3',5'-Cyclic-AMP Phosphodiestera | 2006 |
Treatment of Persistent Pulmonary Hypertension of the Newborn (PPHN) is in its infancy.
Topics: Humans; Hypertension, Pulmonary; Infant, Newborn; Milrinone; Nitric Oxide; Phosphodiesterase Inhibit | 2006 |
Milrinone improves oxygenation in neonates with severe persistent pulmonary hypertension of the newborn.
Topics: Cyclic AMP; Cyclic GMP; Humans; Hypertension, Pulmonary; Infant, Newborn; Milrinone; Oxygen; Phospho | 2006 |
Effects of prostacyclin and milrinone on pulmonary hemodynamics in newborn lambs with persistent pulmonary hypertension induced by ductal ligation.
Topics: Animals; Animals, Newborn; Ductus Arteriosus; Epoprostenol; Fetus; Humans; Hypertension, Pulmonary; | 2006 |
Inhalation of the phosphodiesterase-3 inhibitor milrinone attenuates pulmonary hypertension in a rat model of congestive heart failure.
Topics: Administration, Inhalation; Animals; Cyclic AMP; Cyclic GMP; Disease Models, Animal; Dose-Response R | 2007 |
Preliminary experience with inhaled milrinone in cardiac surgery.
Topics: Administration, Inhalation; Aged; Blood Pressure; Cardiac Surgical Procedures; Cardiopulmonary Bypas | 2007 |
Preliminary experience with inhaled milrinone in cardiac surgery.
Topics: Administration, Inhalation; Aged; Blood Pressure; Cardiac Surgical Procedures; Cardiopulmonary Bypas | 2007 |
Preliminary experience with inhaled milrinone in cardiac surgery.
Topics: Administration, Inhalation; Aged; Blood Pressure; Cardiac Surgical Procedures; Cardiopulmonary Bypas | 2007 |
Preliminary experience with inhaled milrinone in cardiac surgery.
Topics: Administration, Inhalation; Aged; Blood Pressure; Cardiac Surgical Procedures; Cardiopulmonary Bypas | 2007 |
Pulmonary hypertension due to unknown causes in liver resection.
Topics: Adolescent; Embolization, Therapeutic; Hepatectomy; Humans; Hypertension, Pulmonary; Intraoperative | 2007 |
Nebulized milrinone use in a pulmonary hypertensive crisis.
Topics: Acute Disease; Administration, Inhalation; Adult; Antihypertensive Agents; Blood Pressure; Bronchodi | 2007 |
[Acute effect of milrinone on pulmonary hemodynamics in patients with hypoxic pulmonary hypertension].
Topics: Aged; Blood Pressure; Cardiac Output; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Male; M | 1995 |
Effect of bolus milrinone on hemodynamic variables and pulmonary vascular resistance in patients with severe left ventricular dysfunction: a rapid test for reversibility of pulmonary hypertension.
Topics: Adult; Aged; Cardiac Output; Female; Heart Failure; Heart Transplantation; Hemodynamics; Humans; Hyp | 1996 |
Right ventricular failure--insights provided by a new model of chronic pulmonary hypertension.
Topics: Administration, Inhalation; Animals; Blood Pressure; Cardiac Output; Dogs; Heart Rate; Hemodynamics; | 1997 |
Milrinone improves pulmonary hemodynamics and right ventricular function in chronic pulmonary hypertension.
Topics: Animals; Cardiotonic Agents; Chronic Disease; Dogs; Fourier Analysis; Hypertension, Pulmonary; Milri | 1997 |
Pharmacological strategies for improving diastolic dysfunction in the setting of chronic pulmonary hypertension.
Topics: Administration, Inhalation; Animals; Cardiotonic Agents; Chronic Disease; Diastole; Dogs; Heart Vent | 1998 |
Phosphodiesterase III and V inhibitors on pulmonary artery from pulmonary hypertensive rats: differences between early and established pulmonary hypertension.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterase | 1998 |
Hemodynamic and inotropic effects of milrinone after heart transplantation in the setting of recipient pulmonary hypertension.
Topics: Animals; Dogs; Heart Transplantation; Hemodynamics; Hypertension, Pulmonary; Milrinone; Monocrotalin | 1998 |
The use of milrinone in pre-transplant assessment of patients with congestive heart failure and pulmonary hypertension.
Topics: Adult; Aged; Blood Pressure; Cardiac Output; Cardiotonic Agents; Female; Follow-Up Studies; Heart Fa | 1999 |
Milrinone attenuates serotonin-induced pulmonary hypertension and bronchoconstriction in dogs.
Topics: Animals; Bronchoconstriction; Catecholamines; Dogs; Hypertension, Pulmonary; Milrinone; Phosphodiest | 2000 |
Additive effects of inhaled nitric oxide and intravenous milrinone in experimental pulmonary hypertension.
Topics: Adenosine Monophosphate; Administration, Inhalation; Analysis of Variance; Animals; Dose-Response Re | 2000 |
Effect of milrinone on postbypass pulmonary hypertension in children after tetralogy of Fallot repair.
Topics: Adolescent; Adult; Cardiopulmonary Bypass; Child; Child, Preschool; Female; Humans; Hypertension, Pu | 2000 |
Effects of milrinone on platelet aggregation in swine with pulmonary hypertension.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Biological Availability; Blood Gas Analysis; Hemodynamics; Hy | 2000 |
Effects of milrinone on lung water content in dogs with acute pulmonary hypertension.
Topics: Acute Disease; Animals; Body Water; Catheterization; Disease Models, Animal; Dogs; Hemodynamics; Hyp | 1992 |
[Change in pulmonary artery and aorta reactions of isobaric hypoxic pulmonary hypertension in guinea-pig and milrinone's effect].
Topics: Animals; Aorta; Female; Guinea Pigs; Hypertension, Pulmonary; Hypoxia; Male; Milrinone; Muscle Contr | 1991 |
Effects of milrinone on pulmonary vasculature in normal dogs and in dogs with pulmonary hypertension.
Topics: Animals; Blood Pressure; Dogs; Hemodynamics; Hypertension, Pulmonary; Milrinone; Pulmonary Artery; P | 1991 |
Vasodilatory effects of milrinone on pulmonary vasculature in dogs with pulmonary hypertension due to pulmonary embolism: a comparison with those of dopamine and dobutamine.
Topics: Animals; Dobutamine; Dogs; Dopamine; Hypertension, Pulmonary; Milrinone; Pulmonary Circulation; Pulm | 1990 |