milrinone has been researched along with Ductus Arteriosus, Patent in 13 studies
Ductus Arteriosus, Patent: A congenital heart defect characterized by the persistent opening of fetal DUCTUS ARTERIOSUS that connects the PULMONARY ARTERY to the descending aorta (AORTA, DESCENDING) allowing unoxygenated blood to bypass the lung and flow to the PLACENTA. Normally, the ductus is closed shortly after birth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Population pharmacokinetic modeling and simulations suggest a slow loading dose followed by maintenance infusion to reach therapeutic milrinone plasma concentrations within the timeframe of the postligation cardiac syndrome." | 3.91 | Population Pharmacokinetics and Dosing of Milrinone After Patent Ductus Arteriosus Ligation in Preterm Infants. ( Hallik, M; Ilmoja, ML; Jalas, T; Kipper, K; Metsvaht, T; Raidmäe, M; Standing, JF; Starkopf, J; Takkis, K; Tasa, T; Uibo, K; Veigure, R, 2019) |
| " The differential effects of these PDE 3 inhibitors on the near-term and preterm ductus were studied by injecting indomethacin (10 mg/kg) and PDE 3 inhibitors into 21D (21st day of pregnancy: term-21." | 3.73 | In vivo dilatation of the fetal and postnatal ductus arteriosus by inhibition of phosphodiesterase 3 in rats. ( Imamura, S; Momma, K; Nakanishi, T; Toyoshima, K, 2006) |
| "Milrinone is administered after patent ductus arteriosus (PDA) ligation to prevent and treat postoperative hemodynamic instability (i." | 1.91 | Effects of Milrinone on Neonates after Patent Ductus Arteriosus Ligation: A Retrospective Nationwide Database Study. ( Fujita, A; Ito, A; Kashima, K; Kato, M; Kitaoka, H; Konishi, T; Matsui, H; Shitara, Y; Takahashi, N; Yasunaga, H, 2023) |
| "Milrinone was initiated if LVO was < 200 mL/kg/min 1 h after surgery, to prevent PLCS." | 1.72 | Lung ultrasound score parallels trends in systemic haemodynamics after PDA ligation: a case series. ( Cattarossi, L; McNamara, PJ; Savoia, M; Titolo, A, 2022) |
| "Milrinone has been suggested as a possible first-line therapy for preterm neonates to prevent postligation cardiac syndrome (PLCS) through decreasing systemic vascular resistance and increasing cardiac contractility." | 1.46 | Dosing of Milrinone in Preterm Neonates to Prevent Postligation Cardiac Syndrome: Simulation Study Suggests Need for Bolus Infusion. ( Hallik, M; Metsvaht, T; Starkopf, J; Tasa, T, 2017) |
| "Hypotension is a common problem in neonates with complex underlying pathophysiology." | 1.46 | Management of Neonatal Hypotension. ( Kalish, BT, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 8 (61.54) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Savoia, M | 1 |
| McNamara, PJ | 4 |
| Titolo, A | 1 |
| Cattarossi, L | 1 |
| Kitaoka, H | 1 |
| Konishi, T | 1 |
| Shitara, Y | 1 |
| Ito, A | 1 |
| Kashima, K | 1 |
| Fujita, A | 1 |
| Matsui, H | 1 |
| Kato, M | 1 |
| Takahashi, N | 1 |
| Yasunaga, H | 1 |
| Hallik, M | 2 |
| Ilmoja, ML | 1 |
| Tasa, T | 2 |
| Standing, JF | 1 |
| Takkis, K | 1 |
| Veigure, R | 1 |
| Kipper, K | 1 |
| Jalas, T | 1 |
| Raidmäe, M | 1 |
| Uibo, K | 1 |
| Starkopf, J | 2 |
| Metsvaht, T | 2 |
| EL-Khuffash, A | 2 |
| Lapointe, A | 1 |
| Jain, A | 3 |
| El-Khuffash, AF | 1 |
| Weisz, D | 1 |
| Mertens, L | 1 |
| Halliday, M | 1 |
| Kavarana, M | 1 |
| Ebeling, M | 1 |
| Kiger, J | 1 |
| Ting, JY | 1 |
| Resende, M | 1 |
| More, K | 1 |
| Nicholls, D | 1 |
| Weisz, DE | 1 |
| Kalish, BT | 1 |
| Sehgal, A | 1 |
| Francis, JV | 1 |
| Lewis, AI | 1 |
| Seri, I | 1 |
| Noori, S | 1 |
| Osborn, DA | 1 |
| Toyoshima, K | 1 |
| Momma, K | 1 |
| Imamura, S | 1 |
| Nakanishi, T | 1 |
2 reviews available for milrinone and Ductus Arteriosus, Patent
| Article | Year |
|---|---|
Diagnosis and treatment of neonatal hypotension outside the transitional period.
Topics: Adrenal Insufficiency; Dobutamine; Dopamine; Ductus Arteriosus, Patent; Humans; Hypotension; Infant, | 2005 |
Diagnosis and treatment of preterm transitional circulatory compromise.
Topics: Adrenal Cortex Hormones; Blood Circulation; Blood Pressure; Cardiac Output, Low; Dobutamine; Dopamin | 2005 |
11 other studies available for milrinone and Ductus Arteriosus, Patent
| Article | Year |
|---|---|
Lung ultrasound score parallels trends in systemic haemodynamics after PDA ligation: a case series.
Topics: Adult; Birth Weight; Ductus Arteriosus, Patent; Hemodynamics; Humans; Infant; Infant, Newborn; Infan | 2022 |
Effects of Milrinone on Neonates after Patent Ductus Arteriosus Ligation: A Retrospective Nationwide Database Study.
Topics: Bronchopulmonary Dysplasia; Cerebral Hemorrhage; Ductus Arteriosus, Patent; Enterocolitis, Necrotizi | 2023 |
Population Pharmacokinetics and Dosing of Milrinone After Patent Ductus Arteriosus Ligation in Preterm Infants.
Topics: Cardiotonic Agents; Ductus Arteriosus, Patent; Echocardiography; Female; Humans; Hypotension; Infant | 2019 |
Adrenal function in preterm infants undergoing patent ductus arteriosus ligation.
Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Cardiotonic Agents; Cohort Studies; Ductus Arter | 2013 |
Assessment and treatment of post patent ductus arteriosus ligation syndrome.
Topics: Cardiac Output; Cardiotonic Agents; Ductus Arteriosus, Patent; Echocardiography, Doppler; Elasticity | 2014 |
Milrinone use for hemodynamic instability in patent ductus arteriosus ligation.
Topics: Birth Weight; Chi-Square Distribution; Ductus Arteriosus, Patent; Gestational Age; Hemodynamics; Hum | 2017 |
Predictors of respiratory instability in neonates undergoing patient ductus arteriosus ligation after the introduction of targeted milrinone treatment.
Topics: Cardiac Surgical Procedures; Chi-Square Distribution; Ductus Arteriosus, Patent; Echocardiography, D | 2016 |
Dosing of Milrinone in Preterm Neonates to Prevent Postligation Cardiac Syndrome: Simulation Study Suggests Need for Bolus Infusion.
Topics: Cardiac Output; Cardiotonic Agents; Ductus Arteriosus, Patent; Estonia; Female; Gestational Age; Hum | 2017 |
Management of Neonatal Hypotension.
Topics: Blood Pressure; Cardiotonic Agents; Dobutamine; Dopamine; Ductus Arteriosus, Patent; Humans; Hypoten | 2017 |
Use of milrinone in the management of haemodynamic instability following duct ligation.
Topics: Blood Pressure; Ductus Arteriosus, Patent; Heart; Hemodynamics; Humans; Infant, Newborn; Male; Milri | 2011 |
In vivo dilatation of the fetal and postnatal ductus arteriosus by inhibition of phosphodiesterase 3 in rats.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Animals, Newborn; Cyclic Nucleotide Phosphodiesterases | 2006 |