milrinone has been researched along with Cystic Fibrosis in 5 studies
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Previous studies have indicated that milrinone, a specific type III phosphodiesterase inhibitor, may be able to induce chloride secretion in cystic fibrosis (CF) tissues." | 7.70 | The in vivo effects of milrinone on the airways of cystic fibrosis mice and human subjects. ( Alton, EW; Bush, KA; Chadwick, S; Delaney, SJ; Farley, R; Geddes, DM; Jaffe, A; Middleton, PG; Rolleston, S; Smith, SN; Wainwright, B, 1999) |
| "Previous studies have indicated that milrinone, a specific type III phosphodiesterase inhibitor, may be able to induce chloride secretion in cystic fibrosis (CF) tissues." | 3.70 | The in vivo effects of milrinone on the airways of cystic fibrosis mice and human subjects. ( Alton, EW; Bush, KA; Chadwick, S; Delaney, SJ; Farley, R; Geddes, DM; Jaffe, A; Middleton, PG; Rolleston, S; Smith, SN; Wainwright, B, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cobb, BR | 1 |
| Fan, L | 1 |
| Kovacs, TE | 1 |
| Sorscher, EJ | 1 |
| Clancy, JP | 1 |
| Kerem, E | 1 |
| Kelley, TJ | 1 |
| Al-Nakkash, L | 2 |
| Cotton, CU | 1 |
| Drumm, ML | 1 |
| Smith, SN | 1 |
| Middleton, PG | 1 |
| Chadwick, S | 1 |
| Jaffe, A | 1 |
| Bush, KA | 1 |
| Rolleston, S | 1 |
| Farley, R | 1 |
| Delaney, SJ | 1 |
| Wainwright, B | 1 |
| Geddes, DM | 1 |
| Alton, EW | 1 |
| Hwang, TC | 1 |
1 review available for milrinone and Cystic Fibrosis
| Article | Year |
|---|---|
Pharmacological induction of CFTR function in patients with cystic fibrosis: mutation-specific therapy.
Topics: Aminoglycosides; Anti-Bacterial Agents; Benzimidazoles; Chlorophenols; Codon, Nonsense; Cystic Fibro | 2005 |
4 other studies available for milrinone and Cystic Fibrosis
| Article | Year |
|---|---|
Adenosine receptors and phosphodiesterase inhibitors stimulate Cl- secretion in Calu-3 cells.
Topics: Adenosine Deaminase; Anions; Cell Line; Chlorine; Cilostazol; Colforsin; Cyclic AMP; Cystic Fibrosis | 2003 |
Activation of endogenous deltaF508 cystic fibrosis transmembrane conductance regulator by phosphodiesterase inhibition.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Albuterol; Base Sequence; Calcium; Cell Line; | 1996 |
The in vivo effects of milrinone on the airways of cystic fibrosis mice and human subjects.
Topics: Amiloride; Animals; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; | 1999 |
Activation of wild-type and deltaF508-CFTR by phosphodiesterase inhibitors through cAMP-dependent and -independent mechanisms.
Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Animals; Cell Line; Colforsin; Cyclic AMP; Cystic Fibrosis; | 1999 |