Page last updated: 2024-10-31

milrinone and Brain Ischemia

milrinone has been researched along with Brain Ischemia in 11 studies

Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this article is to provide a systematic review of the evidence supporting the use of milrinone for the management of delayed cerebral ischemia (DCI) following subarachnoid hemorrhage (SAH)."8.95The Use of Milrinone in Patients with Delayed Cerebral Ischemia Following Subarachnoid Hemorrhage: A Systematic Review. ( Guichon, C; Lannes, M; Teitelbaum, J; Zeiler, F, 2017)
"Intravenous and intra-arterial milrinone as a rescue measure for delayed cerebral ischemia (DCI) after subarachnoid hemorrhage (SAH) has been adopted by several groups, but so far, evidence for the clinical benefit is unclear and effect on brain perfusion is unknown."8.12Hemodynamic response and clinical outcome following intravenous milrinone plus norepinephrine-based hyperdynamic hypertensive therapy in patients suffering secondary cerebral ischemia after aneurysmal subarachnoid hemorrhage. ( Andereggen, L; Berberat, J; Ensner, R; Marbacher, S; Remonda, L; Steiger, HJ, 2022)
"The role of nimodipine and milrinone in the management of delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (SAH) was studied using clinical and TCD (transcranial Doppler) parameters."8.12Role of Nimodipine and Milrinone in Delayed Cerebral Ischemia. ( Chakrabarti, D; Konar, SK; Kotwal, A; Radhakrishnan, M; Ramalingaiah, AH; Shukla, D; Srinivasaiah, B; Sundaram, M, 2022)
"Intravenous (IV) milrinone is a promising option for the treatment of cerebral vasospasm with delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (aSAH)."7.96Milrinone for refractory cerebral vasospasm with delayed cerebral ischemia. ( Abulhasan, YB; Angle, MR; Ortiz Jimenez, J; Simoneau, G; Teitelbaum, J, 2020)
"Milrinone has been identified as a promising therapeutic agent for DCI, possessing a mechanism of action for the reversal of cerebral vasospasm as well as potentially anti-inflammatory effects to treat the underlying etiology of DCI."6.72Treatment of Subarachnoid Hemorrhage-associated Delayed Cerebral Ischemia With Milrinone: A Review and Proposal. ( Abulhasan, YB; Angle, MR; Aziz-Sultan, MA; Bernier, TD; Chung, DY; Dasenbrock, H; Du, R; Feske, S; Henderson, GV; Izzy, S; Leslie-Mazwi, TM; Nelson, SE; Patel, N; Schontz, MJ, 2021)
"Delayed cerebral ischemia (DCI) is a complication of aneurysmal subarachnoid hemorrhage (aSAH) and is associated with significant morbidity and mortality."5.91Subarachnoid Hemorrhage, Delayed Cerebral Ischemia, and Milrinone Use in Canada. ( Almojuela, A; Bokhari, R; Christie, SD; Duda, T; Eagles, ME; Elkaim, LM; Iorio-Morin, C; Kameda-Smith, MM; Lownie, SP; MacLean, MA; Persad, ARL; Rizzuto, MA; Teitelbaum, J, 2023)
"OBJECTIVE Delayed cerebral ischemia (DCI) is an important complication after aneurysmal subarachnoid hemorrhage (aSAH)."5.48Effect of intrathecal milrinone injection via lumbar catheter on delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage. ( Chin, M; Fukuda, H; Handa, A; Koyanagi, M; Kurosaki, Y; Lo, B; Sadamasa, N; Uezato, M; Yamagata, S, 2018)
"Acute cerebral hypoperfusion following subarachnoid hemorrhage (SAH) is highly related to the pathogenesis of delayed cerebral ischemia (DCI), but the therapeutic option is poorly available."5.46Neurocardiac protection with milrinone for restoring acute cerebral hypoperfusion and delayed ischemic injury after experimental subarachnoid hemorrhage. ( Ishikawa, T; Mutoh, T; Nakamura, K; Sasaki, K; Taki, Y; Tatewaki, Y, 2017)
"Milrinone treatment significantly decreased cerebral infarct size and reversed I/R-induced impairments in memory and motor coordination."5.36Pharmacological preconditioning by milrinone: memory preserving and neuroprotective effect in ischemia-reperfusion injury in mice. ( Jaggi, A; Saklani, R; Singh, N, 2010)
"The purpose of this article is to provide a systematic review of the evidence supporting the use of milrinone for the management of delayed cerebral ischemia (DCI) following subarachnoid hemorrhage (SAH)."4.95The Use of Milrinone in Patients with Delayed Cerebral Ischemia Following Subarachnoid Hemorrhage: A Systematic Review. ( Guichon, C; Lannes, M; Teitelbaum, J; Zeiler, F, 2017)
"Intravenous and intra-arterial milrinone as a rescue measure for delayed cerebral ischemia (DCI) after subarachnoid hemorrhage (SAH) has been adopted by several groups, but so far, evidence for the clinical benefit is unclear and effect on brain perfusion is unknown."4.12Hemodynamic response and clinical outcome following intravenous milrinone plus norepinephrine-based hyperdynamic hypertensive therapy in patients suffering secondary cerebral ischemia after aneurysmal subarachnoid hemorrhage. ( Andereggen, L; Berberat, J; Ensner, R; Marbacher, S; Remonda, L; Steiger, HJ, 2022)
"The role of nimodipine and milrinone in the management of delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (SAH) was studied using clinical and TCD (transcranial Doppler) parameters."4.12Role of Nimodipine and Milrinone in Delayed Cerebral Ischemia. ( Chakrabarti, D; Konar, SK; Kotwal, A; Radhakrishnan, M; Ramalingaiah, AH; Shukla, D; Srinivasaiah, B; Sundaram, M, 2022)
"Intravenous (IV) milrinone is a promising option for the treatment of cerebral vasospasm with delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (aSAH)."3.96Milrinone for refractory cerebral vasospasm with delayed cerebral ischemia. ( Abulhasan, YB; Angle, MR; Ortiz Jimenez, J; Simoneau, G; Teitelbaum, J, 2020)
"Milrinone has been identified as a promising therapeutic agent for DCI, possessing a mechanism of action for the reversal of cerebral vasospasm as well as potentially anti-inflammatory effects to treat the underlying etiology of DCI."2.72Treatment of Subarachnoid Hemorrhage-associated Delayed Cerebral Ischemia With Milrinone: A Review and Proposal. ( Abulhasan, YB; Angle, MR; Aziz-Sultan, MA; Bernier, TD; Chung, DY; Dasenbrock, H; Du, R; Feske, S; Henderson, GV; Izzy, S; Leslie-Mazwi, TM; Nelson, SE; Patel, N; Schontz, MJ, 2021)
"Delayed cerebral ischemia (DCI) is a complication of aneurysmal subarachnoid hemorrhage (aSAH) and is associated with significant morbidity and mortality."1.91Subarachnoid Hemorrhage, Delayed Cerebral Ischemia, and Milrinone Use in Canada. ( Almojuela, A; Bokhari, R; Christie, SD; Duda, T; Eagles, ME; Elkaim, LM; Iorio-Morin, C; Kameda-Smith, MM; Lownie, SP; MacLean, MA; Persad, ARL; Rizzuto, MA; Teitelbaum, J, 2023)
"OBJECTIVE Delayed cerebral ischemia (DCI) is an important complication after aneurysmal subarachnoid hemorrhage (aSAH)."1.48Effect of intrathecal milrinone injection via lumbar catheter on delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage. ( Chin, M; Fukuda, H; Handa, A; Koyanagi, M; Kurosaki, Y; Lo, B; Sadamasa, N; Uezato, M; Yamagata, S, 2018)
"Acute cerebral hypoperfusion following subarachnoid hemorrhage (SAH) is highly related to the pathogenesis of delayed cerebral ischemia (DCI), but the therapeutic option is poorly available."1.46Neurocardiac protection with milrinone for restoring acute cerebral hypoperfusion and delayed ischemic injury after experimental subarachnoid hemorrhage. ( Ishikawa, T; Mutoh, T; Nakamura, K; Sasaki, K; Taki, Y; Tatewaki, Y, 2017)
"Milrinone treatment significantly decreased cerebral infarct size and reversed I/R-induced impairments in memory and motor coordination."1.36Pharmacological preconditioning by milrinone: memory preserving and neuroprotective effect in ischemia-reperfusion injury in mice. ( Jaggi, A; Saklani, R; Singh, N, 2010)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (45.45)24.3611
2020's6 (54.55)2.80

Authors

AuthorsStudies
Steiger, HJ1
Ensner, R1
Andereggen, L1
Remonda, L1
Berberat, J1
Marbacher, S1
Eagles, ME1
MacLean, MA1
Kameda-Smith, MM1
Duda, T1
Persad, ARL1
Almojuela, A1
Bokhari, R1
Iorio-Morin, C1
Elkaim, LM1
Rizzuto, MA1
Lownie, SP1
Christie, SD1
Teitelbaum, J3
Kotwal, A1
Ramalingaiah, AH1
Shukla, D1
Radhakrishnan, M1
Konar, SK1
Srinivasaiah, B1
Chakrabarti, D1
Sundaram, M1
Abulhasan, YB2
Ortiz Jimenez, J1
Simoneau, G1
Angle, MR2
Bernier, TD1
Schontz, MJ1
Izzy, S1
Chung, DY1
Nelson, SE1
Leslie-Mazwi, TM1
Henderson, GV1
Dasenbrock, H1
Patel, N1
Aziz-Sultan, MA1
Feske, S1
Du, R1
Castle-Kirszbaum, M1
Lai, L1
Maingard, J1
Asadi, H1
Danks, RA1
Goldschlager, T1
Chandra, RV1
Lannes, M1
Zeiler, F1
Guichon, C1
Mutoh, T4
Nakamura, K2
Yamamoto, Y1
Tsuru, Y1
Tsubone, H1
Ishikawa, T2
Taki, Y2
Sasaki, K1
Tatewaki, Y1
Koyanagi, M1
Fukuda, H1
Lo, B1
Uezato, M1
Kurosaki, Y1
Sadamasa, N1
Handa, A1
Chin, M1
Yamagata, S1
Saklani, R1
Jaggi, A1
Singh, N1

Reviews

3 reviews available for milrinone and Brain Ischemia

ArticleYear
Treatment of Subarachnoid Hemorrhage-associated Delayed Cerebral Ischemia With Milrinone: A Review and Proposal.
    Journal of neurosurgical anesthesiology, 2021, Jul-01, Volume: 33, Issue:3

    Topics: Brain Ischemia; Humans; Milrinone; Multicenter Studies as Topic; Randomized Controlled Trials as Top

2021
Intravenous milrinone for treatment of delayed cerebral ischaemia following subarachnoid haemorrhage: a pooled systematic review.
    Neurosurgical review, 2021, Volume: 44, Issue:6

    Topics: Brain Ischemia; Cerebral Infarction; Female; Humans; Male; Middle Aged; Milrinone; Pharmaceutical Pr

2021
The Use of Milrinone in Patients with Delayed Cerebral Ischemia Following Subarachnoid Hemorrhage: A Systematic Review.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2017, Volume: 44, Issue:2

    Topics: Brain Ischemia; Humans; Milrinone; Subarachnoid Hemorrhage; Vasodilator Agents

2017

Other Studies

8 other studies available for milrinone and Brain Ischemia

ArticleYear
Hemodynamic response and clinical outcome following intravenous milrinone plus norepinephrine-based hyperdynamic hypertensive therapy in patients suffering secondary cerebral ischemia after aneurysmal subarachnoid hemorrhage.
    Acta neurochirurgica, 2022, Volume: 164, Issue:3

    Topics: Brain Ischemia; Cerebral Infarction; Hemodynamics; Humans; Hypertension; Milrinone; Nimodipine; Nore

2022
Subarachnoid Hemorrhage, Delayed Cerebral Ischemia, and Milrinone Use in Canada.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2023, Volume: 50, Issue:3

    Topics: Brain Ischemia; Canada; Cerebral Infarction; Cross-Sectional Studies; Humans; Milrinone; Subarachnoi

2023
Role of Nimodipine and Milrinone in Delayed Cerebral Ischemia.
    World neurosurgery, 2022, Volume: 166

    Topics: Brain Ischemia; Cerebral Infarction; Humans; Milrinone; Nimodipine; Subarachnoid Hemorrhage; Vasospa

2022
Milrinone for refractory cerebral vasospasm with delayed cerebral ischemia.
    Journal of neurosurgery, 2020, Mar-27, Volume: 134, Issue:3

    Topics: Adult; Aged; Angioplasty; Brain Ischemia; Cohort Studies; Female; Follow-Up Studies; Humans; Injecti

2020
Acute cardiac support with intravenous milrinone promotes recovery from early brain injury in a murine model of severe subarachnoid haemorrhage.
    Clinical and experimental pharmacology & physiology, 2017, Volume: 44, Issue:4

    Topics: Administration, Intravenous; Animals; Brain Injuries; Brain Ischemia; Cerebrovascular Circulation; D

2017
Neurocardiac protection with milrinone for restoring acute cerebral hypoperfusion and delayed ischemic injury after experimental subarachnoid hemorrhage.
    Neuroscience letters, 2017, 02-15, Volume: 640

    Topics: Animals; Brain Ischemia; Cardiotonic Agents; Cerebral Cortex; Echocardiography, Doppler; Heart; Male

2017
Effect of intrathecal milrinone injection via lumbar catheter on delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage.
    Journal of neurosurgery, 2018, Volume: 128, Issue:3

    Topics: Aged; Brain Ischemia; Catheters; Female; Humans; Injections, Spinal; Male; Middle Aged; Milrinone; S

2018
Pharmacological preconditioning by milrinone: memory preserving and neuroprotective effect in ischemia-reperfusion injury in mice.
    Archives of pharmacal research, 2010, Volume: 33, Issue:7

    Topics: Animals; Brain Ischemia; Ischemic Preconditioning; Male; Maze Learning; Memory Disorders; Mice; Milr

2010