Page last updated: 2024-10-31

milrinone and Body Weight

milrinone has been researched along with Body Weight in 8 studies

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
" Allometrically scaled body weight, AKI stages, and maturation function were identified as significant predictors of milrinone clearance."9.30Developmental Pharmacokinetics and Age-Appropriate Dosing Design of Milrinone in Neonates and Infants with Acute Kidney Injury Following Cardiac Surgery. ( Alten, J; Cooper, DS; Gao, Z; Gist, KM; Goldstein, SL; Mizuno, T; Vinks, AA; Wempe, MF, 2019)
"The effects of oral milrinone treatment in cardiomyopathic hamsters with severe congestive heart failure (CHF) were evaluated."7.67Effects of milrinone treatment in cardiomyopathic hamsters (CHF 147) with severe congestive heart failure. ( Cauchy, MJ; Desjardins, S; Hubert, RS; Mueller, RW, 1989)
"The long-term survival of rats with healed myocardial infarction and congestive heart failure treated with milrinone, enalapril and the combination of milrinone plus enalapril, was documented."7.67Beneficial effects of milrinone and enalapril on long-term survival of rats with healed myocardial infarction. ( Emmert, SE; Heyse, JF; Ludden, CT; Stabilito, II; Sweet, CS, 1988)
" Allometrically scaled body weight, AKI stages, and maturation function were identified as significant predictors of milrinone clearance."5.30Developmental Pharmacokinetics and Age-Appropriate Dosing Design of Milrinone in Neonates and Infants with Acute Kidney Injury Following Cardiac Surgery. ( Alten, J; Cooper, DS; Gao, Z; Gist, KM; Goldstein, SL; Mizuno, T; Vinks, AA; Wempe, MF, 2019)
"The effects of oral milrinone treatment in cardiomyopathic hamsters with severe congestive heart failure (CHF) were evaluated."3.67Effects of milrinone treatment in cardiomyopathic hamsters (CHF 147) with severe congestive heart failure. ( Cauchy, MJ; Desjardins, S; Hubert, RS; Mueller, RW, 1989)
"The long-term survival of rats with healed myocardial infarction and congestive heart failure treated with milrinone, enalapril and the combination of milrinone plus enalapril, was documented."3.67Beneficial effects of milrinone and enalapril on long-term survival of rats with healed myocardial infarction. ( Emmert, SE; Heyse, JF; Ludden, CT; Stabilito, II; Sweet, CS, 1988)
"The echocardiographic presence of mild aortic regurgitation combined with left ventricular hypocontractility in a structurally normal heart should alert the physician to the presence of underlying hypertension."1.39Neonatal circulatory failure due to acute hypertensive crisis: clinical and echocardiographic clues. ( Allegaert, K; Brown, S; Cools, B; Eyskens, B; Gewillig, M; Heying, R; Levtchenko, E; Louw, J; Smits, A; Thewissen, L, 2013)
"Milrinone has been shown to increase cardiac output in children after cardiac surgery, but pharmacokinetic analysis has not been used to identify effective dose regimens."1.30The pharmacokinetics of milrinone in pediatric patients after cardiac surgery. ( Bailey, JM; Kanter, KR; Lu, W; Miller, BE; Tam, VK; Tosone, SR, 1999)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's2 (25.00)18.2507
2000's2 (25.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mizuno, T1
Gist, KM1
Gao, Z1
Wempe, MF1
Alten, J1
Cooper, DS1
Goldstein, SL1
Vinks, AA1
Louw, J1
Brown, S1
Thewissen, L1
Smits, A1
Eyskens, B1
Heying, R1
Cools, B1
Levtchenko, E1
Allegaert, K1
Gewillig, M1
Rohlicek, CV1
Viau, S1
Trieu, P1
Hébert, TE1
Zhang, Q1
Lazar, M1
Molino, B1
Rodriguez, R1
Davidov, T1
Su, J1
Tse, J1
Weiss, HR2
Scholz, PM2
Straznicka, M1
Leone, RJ1
Bailey, JM1
Miller, BE1
Lu, W1
Tosone, SR1
Kanter, KR1
Tam, VK1
Desjardins, S1
Mueller, RW1
Hubert, RS1
Cauchy, MJ1
Sweet, CS1
Ludden, CT1
Stabilito, II1
Emmert, SE1
Heyse, JF1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
USE OF ACUTE KIDNEY INJURY BIOMARKERS TO PREDICT IMPAIRED MILRINONE PHARMACOKINETICS IN CHILDREN FOLLOWING CARDIAC SURGERY[NCT01966237]92 participants (Actual)Observational2013-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for milrinone and Body Weight

ArticleYear
Developmental Pharmacokinetics and Age-Appropriate Dosing Design of Milrinone in Neonates and Infants with Acute Kidney Injury Following Cardiac Surgery.
    Clinical pharmacokinetics, 2019, Volume: 58, Issue:6

    Topics: Acute Kidney Injury; Aging; Body Weight; Cardiac Output, Low; Cardiac Surgical Procedures; Dose-Resp

2019

Other Studies

7 other studies available for milrinone and Body Weight

ArticleYear
Neonatal circulatory failure due to acute hypertensive crisis: clinical and echocardiographic clues.
    Cardiovascular journal of Africa, 2013, Volume: 24, Issue:3

    Topics: Acute Disease; Antihypertensive Agents; Aortic Valve Insufficiency; Arterial Pressure; Body Weight;

2013
Effects of neonatal hypoxia in the rat on inotropic stimulation of the adult heart.
    Cardiovascular research, 2005, Mar-01, Volume: 65, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Animals, Newborn; Body Weight; Cardiotonic Agents; Dobutamine;

2005
Reduction in interaction between cGMP and cAMP in dog ventricular myocytes with hypertrophic failure.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 289, Issue:3

    Topics: Adenine; Animals; Body Weight; Cardiotonic Agents; Cyclic AMP; Cyclic GMP; Dogs; Drug Interactions;

2005
Myocardial effects of cyclic AMP phosphodiesterase inhibition are dampened in thyroxine-induced cardiac hypertrophy.
    The Journal of surgical research, 1998, Volume: 76, Issue:1

    Topics: Animals; Blood Gas Analysis; Body Weight; Cardiomegaly; Coronary Circulation; Cyclic AMP; Endocardiu

1998
The pharmacokinetics of milrinone in pediatric patients after cardiac surgery.
    Anesthesiology, 1999, Volume: 90, Issue:4

    Topics: Body Weight; Heart Defects, Congenital; Hemodynamics; Humans; Infant; Milrinone; Models, Biological;

1999
Effects of milrinone treatment in cardiomyopathic hamsters (CHF 147) with severe congestive heart failure.
    Cardiovascular research, 1989, Volume: 23, Issue:7

    Topics: Animals; Body Weight; Calcium; Cardiomyopathy, Dilated; Cardiotonic Agents; Cricetinae; Disease Mode

1989
Beneficial effects of milrinone and enalapril on long-term survival of rats with healed myocardial infarction.
    European journal of pharmacology, 1988, Feb-16, Volume: 147, Issue:1

    Topics: Animals; Body Weight; Cardiomegaly; Cardiotonic Agents; Electrocardiography; Enalapril; Heart Failur

1988