milrinone has been researched along with Aortic Valve Stenosis in 5 studies
Aortic Valve Stenosis: A pathological constriction that can occur above (supravalvular stenosis), below (subvalvular stenosis), or at the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim was to test the hypothesis that local myocardial work and O2 consumption would respond differentially to milrinone, a selective cyclic AMP-phosphodiesterase inhibitor, in left ventricular hypertrophy due to differences in myocardial cyclic AMP-phosphodiesterase activity." | 7.69 | Milrinone, a cyclic AMP-phosphodiesterase inhibitor, has differential effects on regional myocardial work and oxygen consumption in experimental left ventricular hypertrophy. ( Cheinberg, BV; Chiu, WC; Kedem, J; Scholz, PM; Tse, J; Weiss, HR, 1994) |
| "The aim of the present study was to compare the effects of milrinone and levosimendan on right ventricular (RV) inotropy and lusitropy in patients after aortic valve replacement (AVR) for aortic stenosis, a procedure in which an abnormal postoperative RV function may be seen." | 5.34 | Levosimendan or milrinone for right ventricular inotropic treatment?-A secondary analysis of a randomized trial. ( Fredholm, M; Houltz, E; Jörgensen, K; Ricksten, SE, 2020) |
| "We compared the direct inotropic and lusitropic effects of two inodilators, milrinone and levosimendan in patients after aortic valve replacement for aortic stenosis." | 5.27 | Inotropic and lusitropic effects of levosimendan and milrinone assessed by strain echocardiography-A randomised trial. ( Fredholm, M; Houltz, E; Jörgensen, K; Ricksten, SE, 2018) |
| "The aim was to test the hypothesis that local myocardial work and O2 consumption would respond differentially to milrinone, a selective cyclic AMP-phosphodiesterase inhibitor, in left ventricular hypertrophy due to differences in myocardial cyclic AMP-phosphodiesterase activity." | 3.69 | Milrinone, a cyclic AMP-phosphodiesterase inhibitor, has differential effects on regional myocardial work and oxygen consumption in experimental left ventricular hypertrophy. ( Cheinberg, BV; Chiu, WC; Kedem, J; Scholz, PM; Tse, J; Weiss, HR, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fredholm, M | 2 |
| Jörgensen, K | 2 |
| Houltz, E | 2 |
| Ricksten, SE | 2 |
| Ahmed, I | 1 |
| House, CM | 1 |
| Nelson, WB | 1 |
| Maslow, AD | 1 |
| Regan, MM | 1 |
| Schwartz, C | 1 |
| Bert, A | 1 |
| Singh, A | 1 |
| Chiu, WC | 1 |
| Kedem, J | 1 |
| Weiss, HR | 1 |
| Tse, J | 1 |
| Cheinberg, BV | 1 |
| Scholz, PM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| 2- Inhaled Milrinone Prevents the Increase in Pulmonary Artery Pressure After CPB[NCT00819377] | Phase 2 | 124 participants (Anticipated) | Interventional | 2009-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for milrinone and Aortic Valve Stenosis
| Article | Year |
|---|---|
Levosimendan or milrinone for right ventricular inotropic treatment?-A secondary analysis of a randomized trial.
Topics: Aged; Aged, 80 and over; Aortic Valve; Aortic Valve Stenosis; Cardiotonic Agents; Female; Heart Valv | 2020 |
Inotropic and lusitropic effects of levosimendan and milrinone assessed by strain echocardiography-A randomised trial.
Topics: Aged; Aortic Valve; Aortic Valve Stenosis; Cardiac Output; Cardiotonic Agents; Catheterization, Peri | 2018 |
Inotropes improve right heart function in patients undergoing aortic valve replacement for aortic stenosis.
Topics: Adrenergic alpha-Agonists; Aged; Aortic Valve; Aortic Valve Stenosis; Cardiac Surgical Procedures; C | 2004 |
2 other studies available for milrinone and Aortic Valve Stenosis
| Article | Year |
|---|---|
Predictors of inotrope use in patients undergoing concomitant coronary artery bypass graft (CABG) and aortic valve replacement (AVR) surgeries at separation from cardiopulmonary bypass (CPB).
Topics: Aged; Aortic Valve; Aortic Valve Insufficiency; Aortic Valve Stenosis; Cardiopulmonary Bypass; Cardi | 2009 |
Milrinone, a cyclic AMP-phosphodiesterase inhibitor, has differential effects on regional myocardial work and oxygen consumption in experimental left ventricular hypertrophy.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Aortic Valve Stenosis; Disease Models, Animal; Dogs; H | 1994 |