Page last updated: 2024-10-31

milrinone and ACD-MPV

milrinone has been researched along with ACD-MPV in 13 studies

Research Excerpts

ExcerptRelevanceReference
"Milrinone was started at an initial dose of 50 mcg/kg, followed by continuous infusion of 0."5.38Heart failure treated with low-dose milrinone in a full-term newborn. ( Janota, J; Sebková, S; Tomek, V; Zemanová, P, 2012)
"It is therefore important to avoid both hypoxemia and hyperoxemia in the management of PPHN."2.53Considerations in the management of hypoxemic respiratory failure and persistent pulmonary hypertension in term and late preterm neonates. ( Konduri, GG; Lakshminrusimha, S; Steinhorn, RH, 2016)
"Milrinone is a phosphodiesterase III inhibitor which induces pulmonary vasodilatation by its actions through a cyclic adenylate monophosphate mediated signaling pathway."2.46Milrinone for persistent pulmonary hypertension of the newborn. ( Bassler, D; Kirpalani, H; Kreutzer, K; McNamara, P, 2010)
"Milrinone was started at an initial dose of 50 mcg/kg, followed by continuous infusion of 0."1.38Heart failure treated with low-dose milrinone in a full-term newborn. ( Janota, J; Sebková, S; Tomek, V; Zemanová, P, 2012)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (15.38)29.6817
2010's6 (46.15)24.3611
2020's5 (38.46)2.80

Authors

AuthorsStudies
Dillard, J1
Pavlek, LR1
Korada, S1
Chen, B1
Imam, SS1
El-Farrash, RA1
Taha, AS1
Saleh, GA1
Choobdar, FA1
Shahhosseini, P1
Vahedi, Z1
Khosravi, N1
Khalesi, N1
Ghassemzadeh, M1
Qasim, A1
Jain, SK1
Mandell, E1
Kinsella, JP1
Abman, SH1
Luecke, C1
McPherson, C1
Dempsey, E1
Rabe, H1
Lakshminrusimha, S1
Konduri, GG1
Steinhorn, RH2
Latini, G1
Del Vecchio, A1
De Felice, C1
Verrotti, A1
Bossone, E1
Bassler, D2
Kreutzer, K1
McNamara, P2
Kirpalani, H2
Sebková, S1
Tomek, V1
Zemanová, P1
Janota, J1
Choong, K1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Milrinone Versus Sildenafil in Treatment of PPHN in Neonates[NCT04391478]Phase 140 participants (Actual)Interventional2015-01-31Completed
Effectiveness of Nebulized Magnesium Sulfate Combined With Sildenafil Citrate in Persistent Pulmonary Hypertension of Newborn[NCT04898114]Phase 1/Phase 240 participants (Anticipated)Interventional2021-06-02Recruiting
Does Closed-loop Automated Oxygen Control During Mechanical Ventilation Reduce Hypoxic Events? A Randomised Controlled Crossover Study in Ventilated Infants[NCT05017727]31 participants (Actual)Observational2021-10-05Completed
Does Closed-loop Automated Oxygen Control During Mechanical Ventilation Reduce the Duration of Supplementary Oxygen Treatment and the Amount of Time Spent in Hyperoxia? A Randomised Trial in Ventilated Infants Born at or Near Term[NCT05657795]40 participants (Anticipated)Interventional2022-12-07Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

8 reviews available for milrinone and ACD-MPV

ArticleYear
Milrinone Use in Persistent Pulmonary Hypertension of the Newborn.
    NeoReviews, 2020, Volume: 21, Issue:3

    Topics: Cardiotonic Agents; Humans; Infant, Newborn; Milrinone; Persistent Fetal Circulation Syndrome; Vasoc

2020
Persistent pulmonary hypertension of the newborn.
    Pediatric pulmonology, 2021, Volume: 56, Issue:3

    Topics: Bosentan; Epoprostenol; Humans; Hypertension, Pulmonary; Hypoxia; Infant; Infant, Newborn; Infant, P

2021
Treatment of Persistent Pulmonary Hypertension of the Newborn: Use of Pulmonary Vasodilators in Term Neonates.
    Neonatal network : NN, 2017, May-01, Volume: 36, Issue:3

    Topics: Bosentan; Humans; Infant, Newborn; Milrinone; Nitric Oxide; Oxygen Inhalation Therapy; Persistent Fe

2017
The Use of Cardiotonic Drugs in Neonates.
    Clinics in perinatology, 2019, Volume: 46, Issue:2

    Topics: Adrenal Cortex Hormones; Asphyxia Neonatorum; Cardiotonic Agents; Dobutamine; Dopamine; Heart Defect

2019
Considerations in the management of hypoxemic respiratory failure and persistent pulmonary hypertension in term and late preterm neonates.
    Journal of perinatology : official journal of the California Perinatal Association, 2016, Volume: 36 Suppl 2

    Topics: Administration, Inhalation; Animals; Extracorporeal Membrane Oxygenation; Humans; Hyperoxia; Hypoxia

2016
Considerations in the management of hypoxemic respiratory failure and persistent pulmonary hypertension in term and late preterm neonates.
    Journal of perinatology : official journal of the California Perinatal Association, 2016, Volume: 36 Suppl 2

    Topics: Administration, Inhalation; Animals; Extracorporeal Membrane Oxygenation; Humans; Hyperoxia; Hypoxia

2016
Considerations in the management of hypoxemic respiratory failure and persistent pulmonary hypertension in term and late preterm neonates.
    Journal of perinatology : official journal of the California Perinatal Association, 2016, Volume: 36 Suppl 2

    Topics: Administration, Inhalation; Animals; Extracorporeal Membrane Oxygenation; Humans; Hyperoxia; Hypoxia

2016
Considerations in the management of hypoxemic respiratory failure and persistent pulmonary hypertension in term and late preterm neonates.
    Journal of perinatology : official journal of the California Perinatal Association, 2016, Volume: 36 Suppl 2

    Topics: Administration, Inhalation; Animals; Extracorporeal Membrane Oxygenation; Humans; Hyperoxia; Hypoxia

2016
Advances in Neonatal Pulmonary Hypertension.
    Neonatology, 2016, Volume: 109, Issue:4

    Topics: Administration, Inhalation; Disease Management; Extracorporeal Membrane Oxygenation; Humans; Hydroco

2016
Persistent pulmonary hypertension of the newborn: therapeutical approach.
    Mini reviews in medicinal chemistry, 2008, Volume: 8, Issue:14

    Topics: Administration, Inhalation; Humans; Infant, Newborn; Milrinone; Nitric Oxide; Persistent Fetal Circu

2008
Milrinone for persistent pulmonary hypertension of the newborn.
    The Cochrane database of systematic reviews, 2010, Nov-10, Issue:11

    Topics: Humans; Infant, Newborn; Milrinone; Persistent Fetal Circulation Syndrome; Vasodilator Agents

2010

Trials

2 trials available for milrinone and ACD-MPV

ArticleYear
Milrinone Versus Sildenafil in Treatment of Neonatal Persistent Pulmonary Hypertension: A Randomized Control Trial.
    Journal of cardiovascular pharmacology, 2022, 11-01, Volume: 80, Issue:5

    Topics: Humans; Hypertension, Pulmonary; Infant, Newborn; Milrinone; Nitric Oxide; Persistent Fetal Circulat

2022
Comparison of the efficacy of inhaled versus infused milrinone in the management of persistent pulmonary hypertension of the newborn in resource-limited settings: A randomized clinical trial.
    Pediatric pulmonology, 2023, Volume: 58, Issue:7

    Topics: Administration, Inhalation; Humans; Hypertension, Pulmonary; Infant, Newborn; Milrinone; Nitric Oxid

2023

Other Studies

3 other studies available for milrinone and ACD-MPV

ArticleYear
Worsened short-term clinical outcomes in a cohort of patients with iNO-unresponsive PPHN: a case for improving iNO responsiveness.
    Journal of perinatology : official journal of the California Perinatal Association, 2022, Volume: 42, Issue:1

    Topics: Administration, Inhalation; Cohort Studies; Humans; Infant, Newborn; Milrinone; Nitric Oxide; Persis

2022
Heart failure treated with low-dose milrinone in a full-term newborn.
    Prague medical report, 2012, Volume: 113, Issue:1

    Topics: Cardiotonic Agents; Female; Heart Failure; Humans; Infant, Newborn; Milrinone; Persistent Fetal Circ

2012
Neonatal persistent pulmonary hypertension treated with milrinone: four case reports.
    Biology of the neonate, 2006, Volume: 89, Issue:1

    Topics: Administration, Inhalation; Animals; Female; Gestational Age; Humans; Hypoxia; Infant, Newborn; Infa

2006