Page last updated: 2024-08-24

milnacipran and Disease Models, Animal

milnacipran has been researched along with Disease Models, Animal in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (35.71)29.6817
2010's15 (53.57)24.3611
2020's3 (10.71)2.80

Authors

AuthorsStudies
Bondi, CO; Cheng, JP; Craine, TJ; Grobengeiser, KO; Iouchmanov, AL; Kutash, LA; Magdelinic, TN; Marshall, IP; Moschonas, EH; O'Neil, DA; Patel, A; Patel, N; Race, NS; Sunleaf, CR1
Haddadi, R; Rashtiani, R1
Hirose, E; Isoda, H; Ito, N; Nagai, T; Odaguchi, H; Sasaki, K1
Chen, M; Hoshino, H; Obata, H; Saito, S; Yang, Y1
Katsuyama, S; Kishikawa, Y; Nakamura, H; Sato, K; Yagi, T1
Erkoseoglu, I; Kadioglu, M; Kalyoncu, NI; Kesim, M; Pepeoglu, D; Yanik, MN; Yaris, E1
Ji, BU; Kim, NK; Kim, ST; Kim, Y; Koo, S; Lee, JE; Li, C1
Dudka, J; Poleszak, E; Serefko, A; Stasiuk, W; Świąder, K; Szopa, A; Wlaź, P; Wyska, E1
Bradbury, MJ; Chen, C; Dyck, B; Fleck, BA; Foster, AC; Grey, J; Johns, M; Jovic, F; Li, B; Madan, A; O'Brien, J; Pick, RR; Saunders, J; Tamiya, J; Tran, JA; Vickers, T; Wen, J; Zhang, M1
Abe, H; Ikeda, T; Ishida, Y; Nakamura, T; Naono, R; Nishimori, T; Takeda, R1
Abe, H; Ebihara, K; Hashiguchi, H; Ikeda, T; Ishida, Y; Matsuo, H; Nishimori, T; Nonaka, H; Takeda, R; Watanabe, Y1
Bantsiele, GB; Bentué-Ferrer, D; Bourin, M; Laviolle, B; Reymann, JM; Saïkali, S1
Kim, SH; Mun, H; Park, KU; Song, J1
Izumi, T; Ohmura, Y; Tsutsui-Kimura, I; Yamaguchi, T; Yoshida, T; Yoshioka, M1
Hanawa, T; Ito, N; Nagai, T; Oikawa, T; Yabe, T; Yamada, H1
Borowicz, KK; Czuczwar, SJ; Furmanek-Karwowska, K; Luszczki, JJ; Morawska, M1
Chwieduk, CM; McCormack, PL1
Doe, N; Kiriyama, M; Takahashi, T1
Bardin, L; Berrocoso, E; Depoortère, R; Ladure, P; Mico, JA; Newman-Tancredi, A; Vitton, O2
Courteix, C; Eschalier, A; Fialip, J; Libert, F; Loiodice, S; Privat, AM; Wattiez, AS1
Alaux-Cantin, S; André, E; Houchi, H; Legastelois, R; Naassila, M; Pierrefiche, O; Simon O'Brien, E; Vilpoux, C1
Aliaga, M; Ardid, D; Bardin, L; Depoortère, R; Meleine, M; Muller, E; Newman-Tancredi, A1
Kato, A; Ogawa, K; Ohnami, S; Ono, H; Shinohara, S; Tanabe, M1
Hemrick-Luecke, SK; Iyengar, S; Simmons, RM; Webster, AA; Xu, JY1
Chen, Q; King, T; Porreca, F; Rao, S; Vanderah, T; Vardanyan, A1
Mashimo, T; Suzuki, T; Tamagaki, S; Ueta, K1
Chang, R; Church, TJ; Jaw-Tsai, S; Martin, WJ; Saito, DR; Smith, JA; Stangeland, EL; Van Dyke, PM; Van Orden, LJ1

Other Studies

28 other study(ies) available for milnacipran and Disease Models, Animal

ArticleYear
Milnacipran Ameliorates Executive Function Impairments following Frontal Lobe Traumatic Brain Injury in Male Rats: A Multimodal Behavioral Assessment.
    Journal of neurotrauma, 2023, Volume: 40, Issue:1-2

    Topics: Animals; Brain Injuries, Traumatic; Disease Models, Animal; Executive Function; Frontal Lobe; Male; Maze Learning; Milnacipran; Rats; Rats, Sprague-Dawley

2023
Anti-inflammatory and anti-hyperalgesic effects of milnacipran in inflamed rats: involvement of myeloperoxidase activity, cytokines and oxidative/nitrosative stress.
    Inflammopharmacology, 2020, Volume: 28, Issue:4

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Cytokines; Disease Models, Animal; Edema; Hyperalgesia; Indomethacin; Inflammation; Interleukin-1beta; Interleukin-6; Male; Malondialdehyde; Milnacipran; Nitric Oxide; Nitrosative Stress; Oxidative Stress; Pain; Peroxidase; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha

2020
Preventive effect of a Kampo medicine, kososan, on recurrent depression in a mouse model of repeated social defeat stress.
    Gene, 2022, Jan-05, Volume: 806

    Topics: Administration, Oral; Animals; Antidepressive Agents; Depression; Disease Models, Animal; Drugs, Chinese Herbal; Gene Expression Profiling; Gene Expression Regulation; Gene Ontology; Hippocampus; Japan; Male; Medicine, Kampo; Mice; Mice, Inbred BALB C; Milnacipran; Molecular Sequence Annotation; Nerve Tissue Proteins; Oligonucleotide Array Sequence Analysis; Recurrence; Social Defeat; Stress, Psychological

2022
Spinal dopaminergic involvement in the antihyperalgesic effect of antidepressants in a rat model of neuropathic pain.
    Neuroscience letters, 2017, 05-10, Volume: 649

    Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents; Cyclopropanes; Disease Models, Animal; Dopamine; Dopamine Antagonists; Duloxetine Hydrochloride; Fluoxetine; Hyperalgesia; Male; Milnacipran; Neuralgia; Pain Threshold; Rats, Sprague-Dawley; Spinal Cord Dorsal Horn; Sulpiride

2017
Effects of repeated milnacipran and fluvoxamine treatment on mechanical allodynia in a mouse paclitaxel-induced neuropathic pain model.
    Biomedical research (Tokyo, Japan), 2013, Volume: 34, Issue:2

    Topics: Animals; Cyclopropanes; Disease Models, Animal; Fluvoxamine; Hyperalgesia; Male; Mice; Milnacipran; Neuralgia; Paclitaxel

2013
The evaluation of analgesic effects of milnacipran and sertraline in tail-flick test.
    Bratislavske lekarske listy, 2014, Volume: 115, Issue:1

    Topics: Analgesics; Animals; Cyclopropanes; Disease Models, Animal; Mice; Mice, Inbred BALB C; Milnacipran; Pain; Pain Measurement; Pain Threshold; Selective Serotonin Reuptake Inhibitors; Sertraline; Tail; Time Factors; Treatment Outcome

2014
Electroacupuncture Enhances the Antiallodynic and Antihyperalgesic Effects of Milnacipran in Neuropathic Rats.
    Anesthesia and analgesia, 2016, Volume: 122, Issue:5

    Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Behavior, Animal; Combined Modality Therapy; Cyclopropanes; Disease Models, Animal; Electroacupuncture; Hyperalgesia; Male; Milnacipran; Motor Activity; Neuralgia; Pain Threshold; Rats, Sprague-Dawley; Reaction Time; Serotonin and Noradrenaline Reuptake Inhibitors; Time Factors

2016
Influence of the selective antagonist of the NR2B subunit of the NMDA receptor, traxoprodil, on the antidepressant-like activity of desipramine, paroxetine, milnacipran, and bupropion in mice.
    Journal of neural transmission (Vienna, Austria : 1996), 2017, Volume: 124, Issue:3

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Brain; Bupropion; Chromatography, High Pressure Liquid; Cyclopropanes; Depressive Disorder; Desipramine; Disease Models, Animal; Drug Interactions; Excitatory Amino Acid Antagonists; Injections, Intraperitoneal; Male; Mice; Milnacipran; Motor Activity; Paroxetine; Piperidines; Receptors, N-Methyl-D-Aspartate

2017
Characterization of thien-2-yl 1S,2R-milnacipran analogues as potent norepinephrine/serotonin transporter inhibitors for the treatment of neuropathic pain.
    Journal of medicinal chemistry, 2008, Nov-27, Volume: 51, Issue:22

    Topics: Administration, Oral; Animals; Biological Availability; Caco-2 Cells; Crystallography, X-Ray; Cyclopropanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Humans; Male; Microsomes, Liver; Milnacipran; Models, Molecular; Molecular Structure; Molecular Weight; Neuralgia; Norepinephrine Plasma Membrane Transport Proteins; Pain Measurement; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Spinal Nerves; Stereoisomerism; Structure-Activity Relationship

2008
Effects of intrathecal administration of newer antidepressants on mechanical allodynia in rat models of neuropathic pain.
    Neuroscience research, 2009, Volume: 63, Issue:1

    Topics: Analgesics; Animals; Antidepressive Agents; Cyclopropanes; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Fluvoxamine; Hyperalgesia; Injections, Spinal; Male; Milnacipran; Pain Threshold; Paroxetine; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Selective Serotonin Reuptake Inhibitors; Serotonin; Spinal Cord

2009
Analgesic effect of milnacipran is associated with c-Fos expression in the anterior cingulate cortex in the rat neuropathic pain model.
    Neuroscience research, 2009, Volume: 64, Issue:4

    Topics: Afferent Pathways; Analgesics; Animals; Biomarkers; Chronic Disease; Cyclopropanes; Disease Models, Animal; Gyrus Cinguli; Immunohistochemistry; Ligation; Milnacipran; Neuralgia; Nociceptors; Pain Measurement; Pain Threshold; Pain, Intractable; Peripheral Nervous System Diseases; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Selective Serotonin Reuptake Inhibitors; Time Factors; Up-Regulation

2009
Behavioral effects of four antidepressants on an ischemic rat model of emotional disturbances.
    Behavioural brain research, 2009, Aug-12, Volume: 201, Issue:2

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Anxiety Disorders; Behavior, Animal; Brain Ischemia; Cyclopropanes; Depressive Disorder; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Fluvoxamine; Hippocampus; Imipramine; Immobility Response, Tonic; Male; Milnacipran; Motor Activity; Rats; Rats, Wistar

2009
Effect of the combined use of tramadol and milnacipran on pain threshold in an animal model of fibromyalgia.
    The Korean journal of internal medicine, 2009, Volume: 24, Issue:2

    Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Behavior, Animal; Cyclopropanes; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Fibromyalgia; Hydrogen-Ion Concentration; Hyperalgesia; Injections, Intraperitoneal; Male; Milnacipran; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Sodium Chloride; Time Factors; Tramadol

2009
The effects of serotonin and/or noradrenaline reuptake inhibitors on impulsive-like action assessed by the three-choice serial reaction time task: a simple and valid model of impulsive action using rats.
    Behavioural pharmacology, 2009, Volume: 20, Issue:5-6

    Topics: Adrenergic Uptake Inhibitors; Animals; Atomoxetine Hydrochloride; Behavior, Animal; Choice Behavior; Cyclopropanes; Disease Models, Animal; Dose-Response Relationship, Drug; Fluvoxamine; Impulsive Behavior; Male; Milnacipran; Nicotine; Nicotinic Agonists; Propylamines; Rats; Rats, Wistar; Reaction Time; Reproducibility of Results; Selective Serotonin Reuptake Inhibitors

2009
A possible mechanism underlying an antidepressive-like effect of Kososan, a Kampo medicine, via the hypothalamic orexinergic system in the stress-induced depression-like model mice.
    Biological & pharmaceutical bulletin, 2009, Volume: 32, Issue:10

    Topics: Animals; Bromodeoxyuridine; Cell Proliferation; Cyclopropanes; Depression; Disease Models, Animal; Drugs, Chinese Herbal; Hippocampus; Hypothalamus; Intracellular Signaling Peptides and Proteins; Magnoliopsida; Male; Medicine, Kampo; Mice; Mice, Inbred Strains; Milnacipran; Neuropeptide Y; Neuropeptides; Neurotransmitter Agents; Norepinephrine; Orexins; Phytotherapy; Selective Serotonin Reuptake Inhibitors; Serotonin; Stress, Psychological

2009
Effect of acute and chronic treatment with milnacipran potentiates the anticonvulsant activity of conventional antiepileptic drugs in the maximal electroshock-induced seizures in mice.
    Psychopharmacology, 2010, Volume: 207, Issue:4

    Topics: Animals; Anticonvulsants; Brain; Cyclopropanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Electroshock; Male; Memory; Mice; Milnacipran; Psychomotor Performance; Seizures; Selective Serotonin Reuptake Inhibitors

2010
Milnacipran: in fibromyalgia.
    Drugs, 2010, Volume: 70, Issue:1

    Topics: Animals; Bronchodilator Agents; Cognition Disorders; Cyclopropanes; Disease Models, Animal; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Fibromyalgia; Humans; Meta-Analysis as Topic; Milnacipran; Muscle Relaxants, Central; Muscle, Skeletal; Nausea; Norepinephrine; Pain; Pain Measurement; Patient Compliance; Patient Satisfaction; Placebos; Sex Factors; Time Factors; Treatment Outcome

2010
Behavioral despair during a water maze learning task in mice.
    Experimental animals, 2010, Volume: 59, Issue:2

    Topics: Animals; Behavior, Animal; Cyclopropanes; Depression; Disease Models, Animal; Escape Reaction; Fluvoxamine; Male; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Milnacipran; Selective Serotonin Reuptake Inhibitors; Swimming

2010
Evaluation of milnacipran, in comparison with amitriptyline, on cold and mechanical allodynia in a rat model of neuropathic pain.
    European journal of pharmacology, 2011, Mar-25, Volume: 655, Issue:1-3

    Topics: Amitriptyline; Analgesics; Animals; Behavior, Animal; Cold Temperature; Constriction; Cyclopropanes; Disease Models, Animal; Hyperalgesia; Milnacipran; Neuralgia; Rats; Sciatic Nerve; Time Factors

2011
Evidence for a differential opioidergic involvement in the analgesic effect of antidepressants: prediction for efficacy in animal models of neuropathic pain?
    British journal of pharmacology, 2011, Volume: 163, Issue:4

    Topics: Analgesics; Animals; Antidepressive Agents; Clomipramine; Cyclopropanes; Diabetes Mellitus, Experimental; Disease Models, Animal; Duloxetine Hydrochloride; Hyperalgesia; Male; Milnacipran; Naloxone; Neuralgia; Rats; Rats, Sprague-Dawley; Thiophenes

2011
Fluoxetine, desipramine, and the dual antidepressant milnacipran reduce alcohol self-administration and/or relapse in dependent rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011, Volume: 36, Issue:7

    Topics: Alcoholism; Analysis of Variance; Animals; Antidepressive Agents; Central Nervous System Depressants; Conditioning, Operant; Cyclopropanes; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Extinction, Psychological; Female; Fluoxetine; Locomotion; Male; Mice; Mice, Inbred DBA; Milnacipran; Rats; Rats, Wistar; Self Administration

2011
Effects of milnacipran, duloxetine and indomethacin, in polyarthritic rats using the Randall-Selitto model.
    Behavioural pharmacology, 2011, Volume: 22, Issue:5-6

    Topics: Adrenergic Uptake Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cyclopropanes; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Indomethacin; Male; Milnacipran; Rats; Rats, Wistar; Thiophenes

2011
Milnacipran is active in models of irritable bowel syndrome and abdominal visceral pain in rodents.
    European journal of pharmacology, 2011, Dec-15, Volume: 672, Issue:1-3

    Topics: Abdominal Pain; Acetic Acid; Analgesics; Animals; Butyrates; Cyclopropanes; Disease Models, Animal; Drug Administration Schedule; Irritable Bowel Syndrome; Male; Mice; Milnacipran; Rats; Visceral Pain

2011
Effects of milnacipran, a 5-HT and noradrenaline reuptake inhibitor, on C-fibre-evoked field potentials in spinal long-term potentiation and neuropathic pain.
    British journal of pharmacology, 2012, Volume: 167, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Animals; Cyclopropanes; Disease Models, Animal; Electric Stimulation; Evoked Potentials; Long-Term Potentiation; Male; Milnacipran; Nerve Fibers, Unmyelinated; Neuralgia; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Spinal Cord; Synaptic Transmission

2012
Efficacy of duloxetine, a potent and balanced serotonin-norepinephrine reuptake inhibitor in persistent pain models in rats.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:2

    Topics: Acute Disease; Amines; Amitriptyline; Animals; Conscious Sedation; Cyclohexanecarboxylic Acids; Cyclohexanols; Cyclopropanes; Disease Models, Animal; Drug Therapy, Combination; Duloxetine Hydrochloride; Fluoxetine; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Male; Methyltyrosines; Milnacipran; Neuromuscular Junction; Norepinephrine; p-Chloroamphetamine; Pain; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin; Thiophenes; Venlafaxine Hydrochloride

2004
Differential blockade of nerve injury-induced shift in weight bearing and thermal and tactile hypersensitivity by milnacipran.
    The journal of pain, 2006, Volume: 7, Issue:7

    Topics: Analgesics; Animals; Central Nervous System; Cyclopropanes; Disease Models, Animal; Drug Administration Schedule; Foot; Hyperalgesia; Injections, Intravenous; Injections, Spinal; Ligation; Male; Milnacipran; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Spinal Nerves; Weight-Bearing

2006
Antiallodynic and antihyperalgesic effect of milnacipran in mice with spinal nerve ligation.
    Anesthesia and analgesia, 2008, Volume: 106, Issue:4

    Topics: Analgesics; Animals; Antidepressive Agents; Cyclopropanes; Disease Models, Animal; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Milnacipran; Neuritis; Spinal Cord

2008
A novel class of 3-(phenoxy-phenyl-methyl)-pyrrolidines as potent and balanced norepinephrine and serotonin reuptake inhibitors: synthesis and structure-activity relationships.
    Bioorganic & medicinal chemistry letters, 2013, Mar-01, Volume: 23, Issue:5

    Topics: Animals; Crystallography, X-Ray; Disease Models, Animal; Humans; Nerve Tissue Proteins; Neurotransmitter Uptake Inhibitors; Norepinephrine; Pain; Pyrrolidines; Rats; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship

2013