Page last updated: 2024-08-24

milnacipran and Allodynia

milnacipran has been researched along with Allodynia in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (31.58)29.6817
2010's12 (63.16)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Haddadi, R; Rashtiani, R1
Chen, M; Hoshino, H; Obata, H; Saito, S; Yang, Y1
Katsuyama, S; Kishikawa, Y; Nakamura, H; Sato, K; Yagi, T1
Igawa, K; Ikeda, T; Ishida, Y; Nakamura, T; Naono-Nakayama, R; Nishimori, T; Sakoda, S; Takeda, R1
Makuch, W; Mika, J; Przewlocka, B; Rojewska, E; Zychowska, M1
Andoh, T; Kitamura, R; Kuraishi, Y1
Lucas, YE; Price, DD; Robinson, ME; Staud, R1
Ji, BU; Kim, NK; Kim, ST; Kim, Y; Koo, S; Lee, JE; Li, C1
Harada, S; Matsuura, W; Tokuyama, S1
Abe, H; Ikeda, T; Ishida, Y; Nakamura, T; Naono, R; Nishimori, T; Takeda, R1
Kim, SH; Mun, H; Park, KU; Song, J1
Kimura, M; Nakajima, K; Nishikawa, K; Obata, H; Saito, S; Tobe, M1
Bardin, L; Berrocoso, E; Depoortère, R; Ladure, P; Mico, JA; Newman-Tancredi, A; Vitton, O1
Courteix, C; Eschalier, A; Fialip, J; Libert, F; Loiodice, S; Privat, AM; Wattiez, AS1
Iriuchijima, N; Nakajima, K; Obata, H; Saito, S1
Arcaya, JL; Maixner, W; Quintero, L; Rao, SG; Suarez-Roca, H1
Chen, Q; King, T; Porreca, F; Rao, S; Vanderah, T; Vardanyan, A1
Onal, A; Parlar, A; Ulker, S1
Mashimo, T; Suzuki, T; Tamagaki, S; Ueta, K1

Trials

1 trial(s) available for milnacipran and Allodynia

ArticleYear
Effects of milnacipran on clinical pain and hyperalgesia of patients with fibromyalgia: results of a 6-week randomized controlled trial.
    The journal of pain, 2015, Volume: 16, Issue:8

    Topics: Adult; Analysis of Variance; Area Under Curve; Cyclopropanes; Double-Blind Method; Female; Fibromyalgia; Humans; Hyperalgesia; Male; Middle Aged; Milnacipran; Pain Threshold; Physical Stimulation; Selective Serotonin Reuptake Inhibitors; Surveys and Questionnaires; Treatment Outcome; Visual Analog Scale

2015

Other Studies

18 other study(ies) available for milnacipran and Allodynia

ArticleYear
Anti-inflammatory and anti-hyperalgesic effects of milnacipran in inflamed rats: involvement of myeloperoxidase activity, cytokines and oxidative/nitrosative stress.
    Inflammopharmacology, 2020, Volume: 28, Issue:4

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Cytokines; Disease Models, Animal; Edema; Hyperalgesia; Indomethacin; Inflammation; Interleukin-1beta; Interleukin-6; Male; Malondialdehyde; Milnacipran; Nitric Oxide; Nitrosative Stress; Oxidative Stress; Pain; Peroxidase; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha

2020
Spinal dopaminergic involvement in the antihyperalgesic effect of antidepressants in a rat model of neuropathic pain.
    Neuroscience letters, 2017, 05-10, Volume: 649

    Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents; Cyclopropanes; Disease Models, Animal; Dopamine; Dopamine Antagonists; Duloxetine Hydrochloride; Fluoxetine; Hyperalgesia; Male; Milnacipran; Neuralgia; Pain Threshold; Rats, Sprague-Dawley; Spinal Cord Dorsal Horn; Sulpiride

2017
Effects of repeated milnacipran and fluvoxamine treatment on mechanical allodynia in a mouse paclitaxel-induced neuropathic pain model.
    Biomedical research (Tokyo, Japan), 2013, Volume: 34, Issue:2

    Topics: Animals; Cyclopropanes; Disease Models, Animal; Fluvoxamine; Hyperalgesia; Male; Mice; Milnacipran; Neuralgia; Paclitaxel

2013
The role of spinal serotonin receptor and alpha adrenoceptor on the antiallodynic effects induced by intrathecal milnacipran in chronic constriction injury rats.
    European journal of pharmacology, 2014, Sep-05, Volume: 738

    Topics: Adrenergic alpha-Antagonists; Animals; Constriction; Cyclopropanes; Gene Expression Regulation; Hyperalgesia; Injections, Spinal; Male; Mechanical Phenomena; Milnacipran; Neuralgia; Proto-Oncogene Proteins c-fos; Rats; Receptors, Adrenergic, alpha; Receptors, Serotonin; Serotonin Antagonists; Spinal Cord; Temperature

2014
The influence of microglia activation on the efficacy of amitriptyline, doxepin, milnacipran, venlafaxine and fluoxetine in a rat model of neuropathic pain.
    European journal of pharmacology, 2015, Feb-15, Volume: 749

    Topics: Amitriptyline; Animals; Antidepressive Agents; Calcium-Binding Proteins; Cyclohexanols; Cyclopropanes; Doxepin; Fluoxetine; Ganglia, Spinal; Hyperalgesia; Male; Microfilament Proteins; Microglia; Milnacipran; Neuralgia; Rats, Wistar; Sciatic Nerve; Spinal Cord; Treatment Outcome; Venlafaxine Hydrochloride

2015
Milnacipran inhibits oxaliplatin-induced mechanical allodynia through spinal action in mice.
    Biological & pharmaceutical bulletin, 2015, Volume: 38, Issue:1

    Topics: Animals; Antineoplastic Agents; Cyclopropanes; Drug Administration Routes; Hyperalgesia; Male; Mice, Inbred C57BL; Milnacipran; Organoplatinum Compounds; Oxaliplatin; Selective Serotonin Reuptake Inhibitors; Spinal Cord

2015
Electroacupuncture Enhances the Antiallodynic and Antihyperalgesic Effects of Milnacipran in Neuropathic Rats.
    Anesthesia and analgesia, 2016, Volume: 122, Issue:5

    Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Behavior, Animal; Combined Modality Therapy; Cyclopropanes; Disease Models, Animal; Electroacupuncture; Hyperalgesia; Male; Milnacipran; Motor Activity; Neuralgia; Pain Threshold; Rats, Sprague-Dawley; Reaction Time; Serotonin and Noradrenaline Reuptake Inhibitors; Time Factors

2016
Effects of Adjuvant Analgesics on Cerebral Ischemia-Induced Mechanical Allodynia.
    Biological & pharmaceutical bulletin, 2016, Volume: 39, Issue:5

    Topics: Amines; Analgesics; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents, Tricyclic; Brain Ischemia; Carbamazepine; Chemotherapy, Adjuvant; Cyclohexanecarboxylic Acids; Cyclopropanes; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Imipramine; Indomethacin; Male; Mexiletine; Mice; Milnacipran; Morphine; Neuralgia; Paroxetine; Selective Serotonin Reuptake Inhibitors

2016
Effects of intrathecal administration of newer antidepressants on mechanical allodynia in rat models of neuropathic pain.
    Neuroscience research, 2009, Volume: 63, Issue:1

    Topics: Analgesics; Animals; Antidepressive Agents; Cyclopropanes; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Fluvoxamine; Hyperalgesia; Injections, Spinal; Male; Milnacipran; Pain Threshold; Paroxetine; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Selective Serotonin Reuptake Inhibitors; Serotonin; Spinal Cord

2009
Effect of the combined use of tramadol and milnacipran on pain threshold in an animal model of fibromyalgia.
    The Korean journal of internal medicine, 2009, Volume: 24, Issue:2

    Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Behavior, Animal; Cyclopropanes; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Fibromyalgia; Hydrogen-Ion Concentration; Hyperalgesia; Injections, Intraperitoneal; Male; Milnacipran; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Sodium Chloride; Time Factors; Tramadol

2009
Monoamine-dependent, opioid-independent antihypersensitivity effects of intrathecally administered milnacipran, a serotonin noradrenaline reuptake inhibitor, in a postoperative pain model in rats.
    The Journal of pharmacology and experimental therapeutics, 2010, Sep-01, Volume: 334, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Analgesics, Opioid; Animals; Behavior, Animal; Biogenic Monoamines; Cyclopropanes; Dose-Response Relationship, Drug; Drug Interactions; Foot Injuries; Hyperalgesia; Male; Microdialysis; Milnacipran; Morphine; Norepinephrine; Pain Measurement; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, mu; Serotonin; Spinal Cord

2010
Evaluation of milnacipran, in comparison with amitriptyline, on cold and mechanical allodynia in a rat model of neuropathic pain.
    European journal of pharmacology, 2011, Mar-25, Volume: 655, Issue:1-3

    Topics: Amitriptyline; Analgesics; Animals; Behavior, Animal; Cold Temperature; Constriction; Cyclopropanes; Disease Models, Animal; Hyperalgesia; Milnacipran; Neuralgia; Rats; Sciatic Nerve; Time Factors

2011
Evidence for a differential opioidergic involvement in the analgesic effect of antidepressants: prediction for efficacy in animal models of neuropathic pain?
    British journal of pharmacology, 2011, Volume: 163, Issue:4

    Topics: Analgesics; Animals; Antidepressive Agents; Clomipramine; Cyclopropanes; Diabetes Mellitus, Experimental; Disease Models, Animal; Duloxetine Hydrochloride; Hyperalgesia; Male; Milnacipran; Naloxone; Neuralgia; Rats; Rats, Sprague-Dawley; Thiophenes

2011
An increase in spinal cord noradrenaline is a major contributor to the antihyperalgesic effect of antidepressants after peripheral nerve injury in the rat.
    Pain, 2012, Volume: 153, Issue:5

    Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Antidepressive Agents; Cyclopropanes; Hyperalgesia; Idazoxan; Male; Milnacipran; Norepinephrine; Pain Measurement; Peripheral Nerve Injuries; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Nerves

2012
Stress-induced muscle and cutaneous hyperalgesia: differential effect of milnacipran.
    Physiology & behavior, 2006, Jun-15, Volume: 88, Issue:1-2

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Cyclopropanes; Dose-Response Relationship, Drug; Hyperalgesia; Male; Milnacipran; Muscles; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Skin; Stress, Psychological; Swimming

2006
Differential blockade of nerve injury-induced shift in weight bearing and thermal and tactile hypersensitivity by milnacipran.
    The journal of pain, 2006, Volume: 7, Issue:7

    Topics: Analgesics; Animals; Central Nervous System; Cyclopropanes; Disease Models, Animal; Drug Administration Schedule; Foot; Hyperalgesia; Injections, Intravenous; Injections, Spinal; Ligation; Male; Milnacipran; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Spinal Nerves; Weight-Bearing

2006
Milnacipran attenuates hyperalgesia and potentiates antihyperalgesic effect of tramadol in rats with mononeuropathic pain.
    Pharmacology, biochemistry, and behavior, 2007, Volume: 88, Issue:2

    Topics: Analgesics; Animals; Antidepressive Agents; Cyclopropanes; Drug Synergism; Hyperalgesia; Male; Milnacipran; Naloxone; Pain Threshold; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Tramadol

2007
Antiallodynic and antihyperalgesic effect of milnacipran in mice with spinal nerve ligation.
    Anesthesia and analgesia, 2008, Volume: 106, Issue:4

    Topics: Analgesics; Animals; Antidepressive Agents; Cyclopropanes; Disease Models, Animal; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Milnacipran; Neuritis; Spinal Cord

2008