milnacipran has been researched along with Ache in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 15 (42.86) | 29.6817 |
| 2010's | 17 (48.57) | 24.3611 |
| 2020's | 3 (8.57) | 2.80 |
| Authors | Studies |
|---|---|
| Nahata, MC; Nguyen, D; Silva Almodóvar, A | 1 |
| Doucette, JA; Eguale, T; Farag, HM; Goswami, H; Sultan, I; Yunusa, I | 1 |
| Haddadi, R; Rashtiani, R | 1 |
| Alexander, KS; Miller, LL; Patton, TB; Rodriguez, TR; Sarfo, AN | 1 |
| Erkoseoglu, I; Kadioglu, M; Kalyoncu, NI; Kesim, M; Pepeoglu, D; Yanik, MN; Yaris, E | 1 |
| Mease, PJ; Palmer, RH; Wang, Y | 1 |
| Bachmann, G; Brown, C; Foster, D; Ling, F; Rawlinson, L; Wan, J | 1 |
| Carville, S; Choy, E; Fransson, P; Gracely, RH; Ingvar, M; Jensen, KB; Kosek, E; Marcus, H; Petzke, F; Vitton, O; Williams, SC | 1 |
| Dubray, C; Macian, N; Pereira, B; Pickering, G; Shinjo, C | 1 |
| Blate, M; Coplan, JD; Kang, G; Lange, G; Mao, X; Natelson, BH; Shungu, DC; Togo, F; Vu, D; Weiduschat, N | 1 |
| Hozumi, S; Sekine, A; Shimizu, T | 1 |
| Antokhin, EY; Drobizhev, MY; Fedotova, AV; Kikta, SV | 1 |
| Clauw, DJ; Gendreau, RM; Mease, P; Palmer, RH; Wang, Y | 1 |
| Kim, SH; Mun, H; Park, KU; Song, J | 1 |
| Aliaga, M; Bardin, L; Depoortère, R; Gregoire, S; Ladure, P; Malfetes, N; Newman-Tancredi, A; Vitton, O | 1 |
| Chwieduk, CM; McCormack, PL | 1 |
| Branco, JC; Mainguy, Y; Perrot, S; Zachrisson, O | 1 |
| Bitter, I; Karamustafalioglu, O; Koponen, H; Mohr, P; Sartorius, N; Seifritz, E; Svestka, J | 1 |
| Arnold, LM; Gendreau, JF; Gendreau, RM; Palmer, RH; Wang, Y | 1 |
| Linderoth, B; Meyerson, BA; Song, Z | 1 |
| Arnold, LM; Chen, W; Gendreau, RM; Palmer, RH; Saxe, PA | 1 |
| Briley, M | 2 |
| Eisenach, JC; Rao, SG; Shin, SW; Tong, C | 1 |
| Eisenach, JC; Shin, SW | 1 |
| Hemrick-Luecke, SK; Iyengar, S; Simmons, RM; Webster, AA; Xu, JY | 1 |
| Goto, F; Koizuka, S; Nishikawa, K; Obata, H; Saito, S | 1 |
| Kito, S; Koga, Y; Nakajima, T | 1 |
| Clauw, DJ; Gendreau, JF; Gendreau, RM; Gracely, RH; Kranzler, JD; McLean, SA; Mease, PJ; Ribeiro, S; Thorn, MD; Williams, DA | 1 |
| Clauw, DJ; Gendreau, RM; Gracely, RH; Harris, RE; Hufford, M; McLean, SA; Sen, A; Williams, DA | 1 |
| Brooks, VL; Leo, RJ | 1 |
| Simon, LS | 1 |
| Aoki, M; Chiba, H; Harada, Y; Matsumiya, T; Nohara, J; Takeda, H; Tsuji, M | 1 |
| Chang, R; Church, TJ; Jaw-Tsai, S; Martin, WJ; Saito, DR; Smith, JA; Stangeland, EL; Van Dyke, PM; Van Orden, LJ | 1 |
5 review(s) available for milnacipran and Ache
| Article | Year |
|---|---|
Comparison of Amitriptyline and US Food and Drug Administration-Approved Treatments for Fibromyalgia: A Systematic Review and Network Meta-analysis.
Topics: Amitriptyline; Duloxetine Hydrochloride; Fatigue; Female; Fibromyalgia; Humans; Male; Middle Aged; Milnacipran; Network Meta-Analysis; Pain; Pregabalin; United States; United States Food and Drug Administration | 2022 |
[Between depression and fibroniyalgia: the fate of the antidepressant].
Topics: Antidepressive Agents; Cyclopropanes; Depressive Disorder; Fatigue; Fibromyalgia; Humans; Milnacipran; Pain; Russia; Serotonin and Noradrenaline Reuptake Inhibitors | 2016 |
New hope in the treatment of painful symptoms in depression.
Topics: Animals; Antidepressive Agents; Clinical Trials as Topic; Cyclohexanols; Cyclopropanes; Depressive Disorder; Duloxetine Hydrochloride; Humans; Milnacipran; Pain; Thiophenes; Venlafaxine Hydrochloride | 2003 |
Clinical experience with dual action antidepressants in different chronic pain syndromes.
Topics: Antidepressive Agents; Chronic Disease; Cyclohexanols; Cyclopropanes; Duloxetine Hydrochloride; Humans; Milnacipran; Pain; Thiophenes; Venlafaxine Hydrochloride | 2004 |
Clinical potential of milnacipran, a serotonin and norepinephrine reuptake inhibitor, in pain.
Topics: Adrenergic Uptake Inhibitors; Cyclopropanes; Fibromyalgia; Humans; Milnacipran; Pain; Selective Serotonin Reuptake Inhibitors | 2006 |
11 trial(s) available for milnacipran and Ache
| Article | Year |
|---|---|
Effects of milnacipran on the multidimensional aspects of fatigue and the relationship of fatigue to pain and function: pooled analysis of 3 fibromyalgia trials.
Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Cyclopropanes; Double-Blind Method; Fatigue; Female; Fibromyalgia; Humans; Male; Middle Aged; Milnacipran; Pain; Pain Measurement; Randomized Controlled Trials as Topic; Treatment Outcome | 2014 |
Milnacipran in provoked vestibulodynia: efficacy and predictors of treatment success.
Topics: Adolescent; Adult; Analgesics; Cyclopropanes; Female; Humans; Middle Aged; Milnacipran; Pain; Pain Measurement; Treatment Outcome; Vulvodynia; Young Adult | 2015 |
Segregating the cerebral mechanisms of antidepressants and placebo in fibromyalgia.
Topics: Adolescent; Adult; Antidepressive Agents; Brain; Cyclopropanes; Double-Blind Method; Female; Fibromyalgia; Humans; Magnetic Resonance Imaging; Middle Aged; Milnacipran; Pain; Pain Measurement; Pain Perception; Placebo Effect; Pressure; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; Young Adult | 2014 |
Fibromyalgia, milnacipran and experimental pain modulation: study protocol for a double blind randomized controlled trial.
Topics: Adult; Clinical Protocols; Cyclopropanes; Double-Blind Method; Female; Fibromyalgia; France; Hospitals, University; Humans; Milnacipran; Neural Inhibition; Pain; Pain Management; Pain Measurement; Prospective Studies; Selective Serotonin Reuptake Inhibitors | 2015 |
Effect of Milnacipran Treatment on Ventricular Lactate in Fibromyalgia: A Randomized, Double-Blind, Placebo-Controlled Trial.
Topics: Adrenergic Uptake Inhibitors; Adult; Anti-Inflammatory Agents, Non-Steroidal; Attention; Biomarkers; Cerebral Ventricles; Cyclopropanes; Double-Blind Method; Executive Function; Female; Fibromyalgia; Humans; Lactic Acid; Middle Aged; Milnacipran; Nonlinear Dynamics; Pain; Pain Measurement; Proton Magnetic Resonance Spectroscopy; Psychological Tests; Selective Serotonin Reuptake Inhibitors | 2015 |
Milnacipran for the treatment of fibromyalgia in adults: a 15-week, multicenter, randomized, double-blind, placebo-controlled, multiple-dose clinical trial.
Topics: Adult; Aged; Capsules; Constipation; Cyclopropanes; Dizziness; Dose-Response Relationship, Drug; Double-Blind Method; Fatigue; Female; Fibromyalgia; Humans; Male; Middle Aged; Milnacipran; Pain; Pain Measurement; Patient Satisfaction; Placebos; Selective Serotonin Reuptake Inhibitors; Time Factors; Treatment Outcome; Vomiting | 2008 |
A European multicenter randomized double-blind placebo-controlled monotherapy clinical trial of milnacipran in treatment of fibromyalgia.
Topics: Adult; Aged; Cyclopropanes; Double-Blind Method; Drug Administration Schedule; Female; Fibromyalgia; Humans; Male; Middle Aged; Milnacipran; Pain; Pain Measurement; Patient Satisfaction; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome | 2010 |
Efficacy and safety of milnacipran 100 mg/day in patients with fibromyalgia: results of a randomized, double-blind, placebo-controlled trial.
Topics: Adolescent; Adult; Aged; Cyclopropanes; Double-Blind Method; Female; Fibromyalgia; Health Status; Humans; Male; Middle Aged; Milnacipran; Pain; Pain Measurement; Patient Satisfaction; Placebos; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Treatment Outcome; Young Adult | 2010 |
Short-term (2-week) effects of discontinuing milnacipran in patients with fibromyalgia.
Topics: Adult; Blood Pressure; Cyclopropanes; Female; Fibromyalgia; Humans; Male; Middle Aged; Milnacipran; Pain; Treatment Outcome | 2012 |
Efficacy of milnacipran in patients with fibromyalgia.
Topics: Analgesics; Antidepressive Agents, Tricyclic; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fibromyalgia; Humans; Male; Middle Aged; Milnacipran; Pain; Pain Measurement; Selective Serotonin Reuptake Inhibitors; Sickness Impact Profile; Treatment Outcome | 2005 |
Characterization and consequences of pain variability in individuals with fibromyalgia.
Topics: Cyclopropanes; Data Collection; Female; Fibromyalgia; Humans; Male; Medical Records Systems, Computerized; Middle Aged; Milnacipran; Pain; Pain Measurement; Reproducibility of Results; Selective Serotonin Reuptake Inhibitors | 2005 |
19 other study(ies) available for milnacipran and Ache
| Article | Year |
|---|---|
Evidence Needed for Efficacy of Antidepressant Medications Among Patients With Rheumatoid Arthritis.
Topics: Antidepressive Agents; Arthritis, Rheumatoid; Humans; Milnacipran; Pain; Selective Serotonin Reuptake Inhibitors | 2022 |
Anti-inflammatory and anti-hyperalgesic effects of milnacipran in inflamed rats: involvement of myeloperoxidase activity, cytokines and oxidative/nitrosative stress.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Cytokines; Disease Models, Animal; Edema; Hyperalgesia; Indomethacin; Inflammation; Interleukin-1beta; Interleukin-6; Male; Malondialdehyde; Milnacipran; Nitric Oxide; Nitrosative Stress; Oxidative Stress; Pain; Peroxidase; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2020 |
Effects of monoamine uptake inhibitors on pain-related depression of nesting in mice.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Bupropion; Citalopram; Conditioning, Operant; Dopamine Uptake Inhibitors; Fluoxetine; Ketoprofen; Lactic Acid; Male; Mice; Mice, Inbred ICR; Milnacipran; Nesting Behavior; Pain; Receptors, Opioid, kappa; Self Stimulation | 2019 |
The evaluation of analgesic effects of milnacipran and sertraline in tail-flick test.
Topics: Analgesics; Animals; Cyclopropanes; Disease Models, Animal; Mice; Mice, Inbred BALB C; Milnacipran; Pain; Pain Measurement; Pain Threshold; Selective Serotonin Reuptake Inhibitors; Sertraline; Tail; Time Factors; Treatment Outcome | 2014 |
Influence of painful physical symptoms in the treatment of Japanese patients with melancholic major depressive disorder: A prospective cohort study.
Topics: Adult; Aged; Antidepressive Agents; Antidepressive Agents, Tricyclic; Comorbidity; Cyclopropanes; Depressive Disorder; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Milnacipran; Pain; Prospective Studies; Selective Serotonin Reuptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Treatment Outcome | 2016 |
Milnacipran (savella) for fibromyalgia.
Topics: Adrenergic Uptake Inhibitors; Cognition; Cyclopropanes; Drug Approval; Drug Interactions; Fibromyalgia; Humans; Milnacipran; Muscle Fatigue; Pain; Randomized Controlled Trials as Topic; United States; United States Food and Drug Administration | 2009 |
Effect of the combined use of tramadol and milnacipran on pain threshold in an animal model of fibromyalgia.
Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Behavior, Animal; Cyclopropanes; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Fibromyalgia; Hydrogen-Ion Concentration; Hyperalgesia; Injections, Intraperitoneal; Male; Milnacipran; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Sodium Chloride; Time Factors; Tramadol | 2009 |
Comparison of milnacipran, duloxetine and pregabalin in the formalin pain test and in a model of stress-induced ultrasonic vocalizations in rats.
Topics: Adrenergic Uptake Inhibitors; Analgesics; Analysis of Variance; Animals; Cyclopropanes; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Electroshock; Formaldehyde; gamma-Aminobutyric Acid; Male; Milnacipran; Pain; Pain Measurement; Pregabalin; Rats; Rats, Sprague-Dawley; Stress, Physiological; Thiophenes; Vocalization, Animal | 2010 |
Milnacipran: in fibromyalgia.
Topics: Animals; Bronchodilator Agents; Cognition Disorders; Cyclopropanes; Disease Models, Animal; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Fibromyalgia; Humans; Meta-Analysis as Topic; Milnacipran; Muscle Relaxants, Central; Muscle, Skeletal; Nausea; Norepinephrine; Pain; Pain Measurement; Patient Compliance; Patient Satisfaction; Placebos; Sex Factors; Time Factors; Treatment Outcome | 2010 |
Management of depression in the presence of pain symptoms.
Topics: Antidepressive Agents; Brain; Chronic Disease; Clinical Trials as Topic; Combined Modality Therapy; Comorbidity; Cyclohexanols; Cyclopropanes; Depressive Disorder, Major; Drug Therapy, Combination; Duloxetine Hydrochloride; Fibromyalgia; Humans; Milnacipran; Mind-Body Relations, Metaphysical; Norepinephrine; Pain; Psychotherapy; Serotonin; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride | 2010 |
The interaction between antidepressant drugs and the pain-relieving effect of spinal cord stimulation in a rat model of neuropathy.
Topics: Amitriptyline; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Cyclopropanes; Electrodes, Implanted; Fluoxetine; Ligation; Male; Milnacipran; Pain; Pain Management; Pain Measurement; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Selective Serotonin Reuptake Inhibitors; Spinal Cord; Transcutaneous Electric Nerve Stimulation | 2011 |
The monoamine reuptake inhibitor milnacipran does not affect nociception to acute visceral distension in rats.
Topics: Adrenergic alpha-Agonists; Animals; Catheterization; Clonidine; Colon; Cyclopropanes; Electromyography; Female; Injections, Intravenous; Injections, Spinal; Milnacipran; Neurotransmitter Uptake Inhibitors; Ovariectomy; Pain; Physical Stimulation; Rats; Rats, Sprague-Dawley; Rectum; Uterus | 2004 |
Peripheral nerve injury sensitizes the response to visceral distension but not its inhibition by the antidepressant milnacipran.
Topics: Amitriptyline; Animals; Antidepressive Agents; Catheterization; Cyclopropanes; Dose-Response Relationship, Drug; Electromyography; Female; Injections, Spinal; Ligation; Milnacipran; Pain; Pain Threshold; Peripheral Nerve Injuries; Physical Stimulation; Rats; Rats, Sprague-Dawley; Spinal Nerves | 2004 |
Efficacy of duloxetine, a potent and balanced serotonin-norepinephrine reuptake inhibitor in persistent pain models in rats.
Topics: Acute Disease; Amines; Amitriptyline; Animals; Conscious Sedation; Cyclohexanecarboxylic Acids; Cyclohexanols; Cyclopropanes; Disease Models, Animal; Drug Therapy, Combination; Duloxetine Hydrochloride; Fluoxetine; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Male; Methyltyrosines; Milnacipran; Neuromuscular Junction; Norepinephrine; p-Chloroamphetamine; Pain; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin; Thiophenes; Venlafaxine Hydrochloride | 2004 |
The monoamine-mediated antiallodynic effects of intrathecally administered milnacipran, a serotonin noradrenaline reuptake inhibitor, in a rat model of neuropathic pain.
Topics: Adrenergic Uptake Inhibitors; Animals; Cyclopropanes; Dose-Response Relationship, Drug; Injections, Spinal; Male; Milnacipran; Pain; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Spinal Cord | 2005 |
Milnacipran for the drastic improvement of refractory pain in a patient without depressive symptoms: a case report.
Topics: Adrenergic Uptake Inhibitors; Analgesics; Chronic Disease; Cyclopropanes; Depressive Disorder; Dose-Response Relationship, Drug; Femur; Humans; Male; Middle Aged; Milnacipran; Pain; Pain Measurement; Selective Serotonin Reuptake Inhibitors | 2005 |
Is milnacipran effective in treating pain in patients with fibromyalgia?
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Cyclopropanes; Drug Therapy, Combination; Fibromyalgia; Humans; Middle Aged; Milnacipran; Pain; Quality of Life; Randomized Controlled Trials as Topic; Treatment Outcome | 2006 |
Antidepressants enhance the antinociceptive effects of carbamazepine in the acetic acid-induced writhing test in mice.
Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Carbamazepine; Cyclopropanes; Fluvoxamine; Imipramine; Male; Mice; Mice, Inbred ICR; Milnacipran; Pain; Pain Measurement | 2006 |
A novel class of 3-(phenoxy-phenyl-methyl)-pyrrolidines as potent and balanced norepinephrine and serotonin reuptake inhibitors: synthesis and structure-activity relationships.
Topics: Animals; Crystallography, X-Ray; Disease Models, Animal; Humans; Nerve Tissue Proteins; Neurotransmitter Uptake Inhibitors; Norepinephrine; Pain; Pyrrolidines; Rats; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship | 2013 |