mifepristone has been researched along with Uterine Neoplasms in 87 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (4.60) | 18.7374 |
1990's | 23 (26.44) | 18.2507 |
2000's | 26 (29.89) | 29.6817 |
2010's | 29 (33.33) | 24.3611 |
2020's | 5 (5.75) | 2.80 |
Authors | Studies |
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Chae, B; Kim, MR; Park, JY | 1 |
Li, Q; Zhou, G | 1 |
Shen, Q; Sheng, B; Sun, LZ; Zhao, M; Zhu, X; Zou, S | 1 |
Bulun, SE; Coon V, JS; Dai, Y; Dotts, AJ; Kujawa, SA; Liu, S; Shilatifard, A; Xu, J; Yin, P; Zhao, H | 1 |
Dong, X; Guo, R; Hai, N; Hou, Q | 1 |
Peng, F; Shi, S; Ye, Q; Yu, C | 1 |
Chow, TL; Murji, A; Sobel, ML; Whitaker, L | 1 |
Hu, X; Luo, H; Shen, Q; Shu, L; Zhu, X | 1 |
Belland, L; Leyland, N; Murji, A; Singh, SS; von Riedemann, S | 1 |
Bouchard, P; Chabbert-Buffet, N; Daraï, E; Kolanska, K | 1 |
Cui, S; Feng, Q; Liu, P; Wang, Z; Zhang, L | 1 |
Cardini, F; Liu, JP; Xia, Y; Yang, H | 1 |
Agarwal, N; Garg, P; Hari, S; Kriplani, A; Kulshrestha, V; Sareen, N; Thulkar, J | 1 |
Chen, M; Hua, Y; Jiang, W; Shen, Q; Zhang, W; Zhu, X | 1 |
Gilboa, Y; Goldchmit, C; Jakobson-Setton, A; Katz, D; Seidman, DS; Tadir, Y; Yerushalmi, GM | 1 |
Byström, B; Engman, M; Gemzell-Danielsson, K; Hammarsjö, A; Lagerstedt Robinson, K; Lalitkumar, PG; Malmgren, H; Varghese, S | 1 |
Bastianelli, C; Benagiano, G; Brosens, I; Farris, M | 1 |
Abraham, T; Arian, SE; Bartels, CB; Cayton, KC; Chuong, FS; Holthouser, K; Segars, JH | 1 |
Britten, J; Catherino, WH; Cox, J; Malik, M; Patel, A | 1 |
Centini, G; Kashani, BN; Morelli, SS; Petraglia, F; Weiss, G | 1 |
Bragg, B; Chawla, K; Hladky, K; Mark, K | 1 |
Branchini, G; Brum, IS; Capp, E; Corleta, HVE; Pizzolato, LS; Sant'Anna, GDS | 1 |
Akerman, G; Barranger, E; Desfeux, P; Malartic, C; Morel, O; Tulpin, L | 1 |
Eisinger, S; Fiscella, K | 1 |
Acosta, R; Carbonell Esteve, JL; Castañeda, MC; Heredia, B; Hernández, AV; Pérez, Y | 1 |
Bouchard, P; Chabbert-Buffet, N; Ouzounian, S | 1 |
Berry, E; Bulun, S; Chakravarti, D; Clardy, J; Hardt, J; Hoekstra, AV; Kim, JJ; Lu, Z; Marsh, E; Sefton, EC; Yin, P | 1 |
Bagaria, M; Guleria, K; Mishra, K; Suneja, A; Vaid, NB | 1 |
Erenbourg, A; Piccoli, M; Ronfani, L; Tamburlini, G | 1 |
Engman, M; Gemzell-Danielsson, K; Granberg, S; Lalitkumar, PG; Meng, CX; Williams, AR | 1 |
Fraser, IS | 1 |
Bonfiglio, T; Eisinger, SH; Fiscella, J; Fiscella, K; Meldrum, S | 1 |
Spitz, IM | 2 |
Bulun, SE; Ishikawa, H; Lin, Z; Luo, X; Marsh, EE; Pavone, ME; Reierstad, S; Yin, P; Zhao, H | 1 |
Appleman, LJ; Im, A | 1 |
Bulun, SE; Chakravarti, D; Cheng, Y; Coon, JS; Innes, J; Ishikawa, H; Kim, JJ; Lin, Z; Marsh, EE; Pearson, K; Reierstad, S; Wu, J; Yin, P | 1 |
Feng, C; Fiscella, K; Meldrum, S | 1 |
Bulun, SE; Ishi, K; Ishikawa, H; Kakazu, R; Kurita, T; Serna, VA | 1 |
Bulun, SE; Coon, JS; Ishikawa, H; Pearson, EK; Su, E | 1 |
Csatlós, E; Joó, JG; Nagy, Z; Rigó, J; Szabó, I | 1 |
Bonfiglio, T; Eisinger, SH; Fiscella, J; Fiscella, K; Winters, P | 1 |
Bouchard, P | 1 |
Acosta, R; Campos, R; Esteve, JL; Hernández, AV; Pérez, Y; Texidó, CS | 1 |
Bulun, SE; Coon, JS; Dai, Y; Huang, L; Kim, JJ; Monsivais, D; Navarro, A; Owen, JK; Roqueiro, D; Xie, A; Yin, P | 1 |
Angiolucci, M; Guerriero, S; Lello, S; Maricosu, G; Marotto, MF; Melis, GB; Orru', MM; Paoletti, AM; Pilloni, M; Piras, B | 1 |
Orozco, LJ; Ramírez-Morera, A; Steed, A; Stone, P; Tristan, M | 1 |
Schweppe, KW | 1 |
Eisinger, SH; Fiscella, K; Guzick, DS; le Roux, HD; Meldrum, S | 1 |
Jackson, R; Jacoby, AF; Pritts, EA; Steinauer, J | 1 |
Dominguez, CE; Lowe, E; Murphy, AA; Parthasarathy, S; Ramachandran, S; Song, MQ | 1 |
Chen, CL; Liao, QP; Lu, Y; Yu, L | 1 |
Librach, CL; Xiao, R; Yie, SM | 1 |
Eisinger, SH; Feng, C; Fiscella, K; Fisher, SG; Guzick, DS; Meldrum, S | 1 |
Heikinheimo, O; Koivisto-Korander, R; Leminen, A | 1 |
Lee, EW; Leung, PC; Mao, Q; Ross, DD; Unadkat, JD; Wang, H; Zhou, L | 1 |
Kettel, LM; Morales, AJ; Murphy, AA; Yen, SS | 2 |
Castellano, PZ; Murphy, AA | 1 |
Bates, A; Evans, J; Pinto, A | 1 |
Morales, AJ; Murphy, AA; Reinsch, RC; Yen, SS | 1 |
Smith, SK | 1 |
Courtieu, C; Déchaud, H; Marès, P; Marsollier, C; Tailland, ML | 1 |
Kettel, LM; Morales, AJ; Murphy, AA; Roberts, VJ; Yen, SS | 1 |
Kettel, LM | 1 |
Kettel, LM; Morales, AJ; Murphy, AA | 1 |
Bamberger, AM; Erdmann, I; Jenatschke, S; Schulte, HM | 1 |
Li, K; Yang, Y; Zheng, S | 1 |
London, SN; Mahajan, DK | 1 |
Chi, CW; Ho, CK; Wang, SY; Yu, KJ | 1 |
Sitruk-Ware, R | 1 |
Yang, Y; Zhang, Z; Zheng, S | 1 |
Sun, M; Zhou, L; Zhu, G | 1 |
Gu, M; Huang, H; Zeng, C | 1 |
Bright, N; Coleman, RE; Gillespie, AM; Hancock, BW; Radstone, CR; Tidy, JA | 1 |
Boettger-Tong, H; Chiappetta, C; Huang, JC; Hyder, SM; Mäkelä, S; Nawaz, Z; Stancel, GM | 1 |
Matsuda, M; Mitamura, T; Mori, T; Sakamoto, S; Zhou, YF | 1 |
Weng, L | 1 |
Jiang, M; Weng, L; Wu, S; Wu, Y | 1 |
Sun, L; Wang, C; Zheng, Y | 1 |
Jin, J; Wang, H | 1 |
Jiang, J; Sun, HC; Wang, ZH; Wu, RF; Xiu, HM; Xu, Z | 1 |
Azuma, C; Kimura, T; Miki, M; Ono, M; Saji, F; Takemura, M; Tanizawa, O; Tokugawa, Y | 1 |
Bischof, P; Herrmann, WL; Schindler, AM; Sizonenko, PC; Wyss, R | 1 |
Matsumoto, K; Shimizu, I; Tanizawa, O; Terakawa, N | 1 |
Fujimoto, J; Fujita, H; Hosoda, S; Okada, H | 1 |
Okada, H | 1 |
25 review(s) available for mifepristone and Uterine Neoplasms
Article | Year |
---|---|
The efficacy and safety of Xuefu Zhuyu Decoction combined with Mifepristone in the treatment of uterine leiomyoma: A systematic review and meta-analysis.
Topics: Antineoplastic Agents; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Humans; Leiomyoma; Mifepristone; Uterine Neoplasms | 2021 |
Selective progesterone receptor modulators (SPRMs) for uterine fibroids.
Topics: Amenorrhea; Antineoplastic Agents, Hormonal; Estrenes; Female; Humans; Leiomyoma; Leuprolide; Menstruation; Mifepristone; Norpregnadienes; Oximes; Pelvic Pain; Quality of Life; Randomized Controlled Trials as Topic; Receptors, Progesterone; Uterine Neoplasms | 2017 |
The past, present, and future of selective progesterone receptor modulators in the management of uterine fibroids.
Topics: Contraceptive Agents, Female; Disease Management; Estrenes; Female; Forecasting; Humans; Leiomyoma; Mifepristone; Norpregnadienes; Oximes; Population Growth; Receptors, Progesterone; Steroids; Uterine Neoplasms | 2018 |
Selective progesterone receptor modulators: current applications and perspectives.
Topics: Abortion, Induced; Endometriosis; Female; Humans; Leiomyoma; Mifepristone; Norpregnadienes; Pregnancy; Progesterone; Receptors, Progesterone; Uterine Hemorrhage; Uterine Neoplasms | 2018 |
Herbal preparations for uterine fibroids.
Topics: Drugs, Chinese Herbal; Female; Gonadotropin-Releasing Hormone; Hormone Antagonists; Humans; Leiomyoma; Mifepristone; Phytotherapy; Plant Preparations; Randomized Controlled Trials as Topic; Uterine Neoplasms | 2013 |
Effects of mifepristone on uterine leiomyoma in premenopausal women: a meta-analysis.
Topics: Antineoplastic Agents; Drug-Related Side Effects and Adverse Reactions; Evidence-Based Medicine; Female; Humans; Incidence; Leiomyoma; Mifepristone; Premenopause; Risk Factors; Treatment Outcome; Uterine Neoplasms | 2013 |
Selective progesterone receptor modulators: an update.
Topics: Adenomyosis; Animals; Clinical Trials as Topic; Contraception, Postcoital; Contraceptive Agents, Female; Contraceptives, Postcoital; Endometriosis; Estrenes; Female; Hormone Antagonists; Humans; Leiomyoma; Levonorgestrel; Mifepristone; Norpregnadienes; Oximes; Receptors, Progesterone; Uterine Neoplasms | 2014 |
An Evidence-based Approach to the Medical Management of Fibroids: A Systematic Review.
Topics: Androgens; Aromatase Inhibitors; Contraceptive Agents, Female; Contraceptives, Oral, Combined; Curcumin; Delayed-Action Preparations; Drugs, Chinese Herbal; Estradiol; Estrenes; Estrogen Receptor Antagonists; Evidence-Based Medicine; Female; Fulvestrant; Gonadotropin-Releasing Hormone; Hormone Antagonists; Humans; Intrauterine Devices, Medicated; Leiomyoma; Levonorgestrel; Medroxyprogesterone Acetate; Mifepristone; Neoadjuvant Therapy; Norpregnadienes; Oximes; Plant Extracts; Receptors, Progesterone; Selective Estrogen Receptor Modulators; Tea; Uterine Myomectomy; Uterine Neoplasms; Vitamin D; Vitamins | 2016 |
Role of Medical Management for Uterine Leiomyomas.
Topics: Antifibrinolytic Agents; Aromatase Inhibitors; Cabergoline; Cholecalciferol; Contraceptive Agents, Female; Contraceptives, Oral, Hormonal; Contraceptives, Oral, Synthetic; Danazol; Dopamine Agonists; Ergolines; Estrenes; Estrogen Antagonists; Female; Gestrinone; Gonadotropin-Releasing Hormone; Humans; Intrauterine Devices, Medicated; Leiomyoma; Levonorgestrel; Mifepristone; Norpregnadienes; Oximes; Patient Care Planning; Selective Estrogen Receptor Modulators; Somatostatin; Tranexamic Acid; Uterine Neoplasms; Vitamins | 2016 |
[Role of mifepristone for the treatment of uterine fibroid].
Topics: Antineoplastic Agents, Hormonal; Dose-Response Relationship, Drug; Endometrial Hyperplasia; Female; Hot Flashes; Humans; Leiomyoma; Liver; Mifepristone; Treatment Outcome; Uterine Neoplasms | 2008 |
Effects of antiprogestins on the uterus.
Topics: Animals; Contraceptives, Oral, Synthetic; Female; Hormone Antagonists; Humans; Leiomyoma; Metrorrhagia; Mifepristone; Progestins; Receptors, Progesterone; Uterine Neoplasms; Uterus | 2008 |
Clinical utility of progesterone receptor modulators and their effect on the endometrium.
Topics: Drug Administration Schedule; Endometriosis; Endometrium; Estrenes; Female; Hormone Antagonists; Humans; Leiomyoma; Mifepristone; Norpregnadienes; Oximes; Randomized Controlled Trials as Topic; Receptors, Progesterone; Time Factors; Uterine Neoplasms | 2009 |
Mifepristone: pharmacology and clinical impact in reproductive medicine, endocrinology and oncology.
Topics: Abortifacient Agents, Steroidal; Drug Approval; Drug Delivery Systems; Drug Design; Endocrinology; Female; Humans; Medical Oncology; Mifepristone; Pregnancy; Pregnancy Complications, Neoplastic; Reproductive Medicine; Uterine Neoplasms | 2010 |
[Uterine leiomyoma].
Topics: Antineoplastic Agents; Diagnosis, Differential; Estrenes; Female; Hormone Antagonists; Humans; Hysterectomy; Incidence; Laparoscopy; Leiomyoma; Mifepristone; Oximes; Ultrasonic Therapy; Uterine Artery; Uterine Neoplasms | 2010 |
Current and future medical treatments for menometrorrhagia during the premenopause.
Topics: Adolescent; Adult; Contraceptives, Oral; Endometrial Neoplasms; Female; Gonadotropin-Releasing Hormone; Humans; Leiomyoma; Levonorgestrel; Menorrhagia; Metrorrhagia; Mifepristone; Norpregnadienes; Polyps; Premenopause; Progestins; Randomized Controlled Trials as Topic; Receptors, Progesterone; Uterine Neoplasms | 2011 |
Mifepristone for uterine fibroids.
Topics: Female; Humans; Leiomyoma; Menorrhagia; Mifepristone; Premenopause; Randomized Controlled Trials as Topic; Receptors, Progesterone; Tumor Burden; Uterine Neoplasms | 2012 |
Progestins and uterine leiomyoma.
Topics: Danazol; Estrogen Antagonists; Estrogens; Female; Gonadotropin-Releasing Hormone; Hormone Antagonists; Humans; Leiomyoma; Mifepristone; Progesterone; Progestins; Uterine Neoplasms | 1999 |
Progesterone antagonists and progesterone receptor modulators.
Topics: Animals; Contraceptives, Postcoital; Drug Administration Schedule; Endometriosis; Endometrium; Female; Gene Transfer Techniques; Hormone Antagonists; Humans; Leiomyoma; Mifepristone; Progesterone; Receptors, Progesterone; Uterine Neoplasms | 2003 |
Systematic review of mifepristone for the treatment of uterine leiomyomata.
Topics: Adult; Clinical Trials as Topic; Endometrial Hyperplasia; Female; Hormone Antagonists; Humans; Leiomyoma; Middle Aged; Mifepristone; Uterine Neoplasms | 2004 |
RU486: pharmacology and potential use in the treatment of endometriosis and leiomyomata uteri.
Topics: Endometriosis; Endometrium; Female; Humans; Leiomyoma; Mifepristone; Progesterone; Uterine Neoplasms | 1994 |
Clinical applications of the antiprogestins.
Topics: Abortifacient Agents, Steroidal; Breast Neoplasms; Clinical Trials as Topic; Contraceptives, Oral, Synthetic; Cushing Syndrome; Endometriosis; Endometrium; Female; Hormone Antagonists; Humans; Leiomyoma; Meningeal Neoplasms; Meningioma; Menstrual Cycle; Mifepristone; Pregnancy; Pregnancy, Ectopic; Premenstrual Syndrome; Progestins; Uterine Neoplasms | 1995 |
Mifepristone: clinical application in general gynecology.
Topics: Endometriosis; Endometrium; Female; Genital Diseases, Female; Hormone Antagonists; Humans; Leiomyoma; Menstrual Cycle; Mifepristone; Uterine Neoplasms | 1996 |
Mifepristone (RU486): a review.
Topics: Abortifacient Agents, Steroidal; Abortion, Induced; Animals; Breast Neoplasms; Contraceptives, Oral, Synthetic; Contraceptives, Postcoital, Synthetic; Endometriosis; Female; Humans; Leiomyoma; Mifepristone; Pregnancy; Uterine Neoplasms | 1997 |
[Anti-progesterones].
Topics: Abortifacient Agents, Steroidal; Abortion, Therapeutic; Contraceptive Agents; Contraceptives, Oral, Synthetic; Endometriosis; Female; Humans; Leiomyosarcoma; Meningioma; Mifepristone; Pregnancy; Pregnancy Complications, Neoplastic; Progesterone; Progestins; Receptors, Progesterone; Uterine Neoplasms | 1999 |
Regulation of vascular endothelial growth factor expression by estrogens and progestins.
Topics: Breast Neoplasms; Dose-Response Relationship, Drug; Endothelial Growth Factors; Estradiol; Estrogen Antagonists; Estrogens; Female; Fulvestrant; Gene Expression Regulation; Hormone Antagonists; Humans; Leiomyoma; Lymphokines; Mifepristone; Progestins; Receptors, Estrogen; RNA, Messenger; Signal Transduction; Transcription, Genetic; Uterine Neoplasms; Uterus; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2000 |
16 trial(s) available for mifepristone and Uterine Neoplasms
Article | Year |
---|---|
Low dose mifepristone in medical management of uterine leiomyoma - an experience from a tertiary care hospital from north India.
Topics: Administration, Oral; Adult; Cost-Benefit Analysis; Drug Administration Schedule; Female; Follow-Up Studies; Hormone Antagonists; Humans; India; Leiomyoma; Menorrhagia; Middle Aged; Mifepristone; Prospective Studies; Tertiary Care Centers; Treatment Outcome; Uterine Neoplasms | 2013 |
Vaginal mifepristone for the treatment of symptomatic uterine leiomyomata: an open-label study.
Topics: Administration, Intravaginal; Adult; Female; Hormone Antagonists; Humans; Israel; Leiomyoma; Middle Aged; Mifepristone; Prospective Studies; Surveys and Questionnaires; Treatment Outcome; Uterine Neoplasms | 2014 |
GSTM1 gene expression correlates to leiomyoma volume regression in response to mifepristone treatment.
Topics: Biomarkers; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glutathione Transferase; Hormone Antagonists; Humans; Leiomyoma; Mifepristone; Oligonucleotide Array Sequence Analysis; Premenopause; Receptors, Progesterone; Signal Transduction; Tumor Burden; Uterine Neoplasms; Uterus | 2013 |
Mifepristone for the treatment of uterine leiomyomas: a randomized controlled trial.
Topics: Adult; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Hormone Antagonists; Humans; Leiomyomatosis; Middle Aged; Mifepristone; Treatment Outcome; Ultrasonography; Uterine Neoplasms; Uterus | 2008 |
Low-dose mifepristone in treatment of uterine leiomyoma: a randomised double-blind placebo-controlled clinical trial.
Topics: Adult; Double-Blind Method; Drug Administration Schedule; Endometrial Hyperplasia; Female; Follicular Phase; Hormone Antagonists; Humans; Leiomyomatosis; Menorrhagia; Middle Aged; Mifepristone; Placebos; Uterine Neoplasms | 2009 |
Mifepristone for treatment of uterine leiomyoma. A prospective randomized placebo controlled trial.
Topics: Adult; Double-Blind Method; Female; Hemoglobins; Humans; Leiomyoma; Middle Aged; Mifepristone; Regional Blood Flow; Uterine Hemorrhage; Uterine Neoplasms; Uterus | 2009 |
Open-label study of ultra low-dose mifepristone for the treatment of uterine leiomyomata.
Topics: Administration, Oral; Adult; Dose-Response Relationship, Drug; Female; Health Status; Hormone Antagonists; Humans; Leiomyoma; Middle Aged; Mifepristone; Pain; Quality of Life; Uterine Hemorrhage; Uterine Neoplasms | 2009 |
Treatment of uterine myoma with 5 or 10mg mifepristone daily during 6 months, post-treatment evolution over 12 months: double-blind randomised clinical trial.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Double-Blind Method; Fatigue; Female; Follow-Up Studies; Hemoglobins; Hormone Antagonists; Hot Flashes; Humans; Leiomyoma; Menorrhagia; Middle Aged; Mifepristone; Nausea; Pelvic Pain; Uterine Neoplasms; Vomiting | 2012 |
Low-dose mifepristone for uterine leiomyomata.
Topics: Adult; Biopsy, Needle; Blood Chemical Analysis; Dose-Response Relationship, Drug; Drug Administration Schedule; Endosonography; Female; Follow-Up Studies; Hormone Antagonists; Humans; Immunohistochemistry; Leiomyoma; Middle Aged; Mifepristone; Multivariate Analysis; Reference Values; Statistics, Nonparametric; Treatment Outcome; Uterine Neoplasms | 2003 |
Effect of mifepristone for symptomatic leiomyomata on quality of life and uterine size: a randomized controlled trial.
Topics: Adult; Female; Hormone Antagonists; Humans; Leiomyomatosis; Middle Aged; Mifepristone; Organ Size; Pain; Quality of Life; Treatment Outcome; Ultrasonography; Uterine Neoplasms; Uterus | 2006 |
Regression of uterine leiomyomata to the antiprogesterone RU486: dose-response effect.
Topics: Adolescent; Adult; Dose-Response Relationship, Drug; Female; Humans; Leiomyomatosis; Middle Aged; Mifepristone; Prospective Studies; Ultrasonography; Uterine Neoplasms | 1995 |
Clinical efficacy of the antiprogesterone RU486 in the treatment of endometriosis and uterine fibroids.
Topics: Abdominal Pain; Adolescent; Adrenocorticotropic Hormone; Adult; Anovulation; Endometriosis; Estrogens; Female; Humans; Hydrocortisone; Leiomyoma; Luteinizing Hormone; Mifepristone; Pilot Projects; Progesterone; Ultrasonography; Uterine Neoplasms | 1994 |
The effects of RU 486 and leuprolide acetate on uterine artery blood flow in the fibroid uterus: a prospective, randomized study.
Topics: Female; Humans; Leiomyoma; Leuprolide; Mifepristone; Prospective Studies; Regional Blood Flow; Uterine Neoplasms; Uterus | 1994 |
[Treatment of uterine leiomyoma by two different doses of mifepristone].
Topics: Adult; Female; Hormone Antagonists; Humans; Leiomyoma; Middle Aged; Mifepristone; Prospective Studies; Uterine Neoplasms | 1996 |
[Effects of mifepristone on gene expression of epidermal growth factor in human uterine leiomyoma].
Topics: Epidermal Growth Factor; Female; Gene Expression; Hormone Antagonists; Humans; Leiomyoma; Mifepristone; RNA, Messenger; Uterine Neoplasms | 1998 |
[A clinical control study on the treatment of uterine leiomyoma with gonadotrophin releasing hormone agonist or mifepristone].
Topics: Adult; Female; Gonadotropin-Releasing Hormone; Hormone Antagonists; Humans; Leiomyoma; Middle Aged; Mifepristone; Uterine Neoplasms | 1998 |
46 other study(ies) available for mifepristone and Uterine Neoplasms
Article | Year |
---|---|
The Potential of Transforming Growth Factor-beta Inhibitor and Vascular Endothelial Growth Factor Inhibitor as Therapeutic Agents for Uterine Leiomyoma.
Topics: Female; Humans; Intercellular Signaling Peptides and Proteins; Leiomyoma; Mifepristone; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transforming Growth Factors; Uterine Neoplasms; Vascular Endothelial Growth Factor A | 2022 |
Long-term use of ultra-low-dose mifepristone for uterine leiomyoma control and safety discussion: A case report.
Topics: Female; Hormone Antagonists; Humans; Leiomyoma; Menstrual Cycle; Middle Aged; Mifepristone; Uterine Neoplasms | 2022 |
Mifepristone inhibits IGF-1 signaling pathway in the treatment of uterine leiomyomas.
Topics: Adult; Antineoplastic Agents; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Female; Humans; Insulin-Like Growth Factor I; Leiomyoma; Mifepristone; Signal Transduction; Tumor Cells, Cultured; Uterine Neoplasms | 2019 |
Targeting DNA Methylation Depletes Uterine Leiomyoma Stem Cell-enriched Population by Stimulating Their Differentiation.
Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Count; Cell Differentiation; Cells, Cultured; DNA Methylation; Female; Humans; Leiomyoma; Mice; Mice, SCID; Mice, Transgenic; Middle Aged; Mifepristone; Molecular Targeted Therapy; Neoplastic Stem Cells; Uterine Neoplasms; Xenograft Model Antitumor Assays | 2020 |
Comparison between radiofrequency ablation combined with mifepristone and radiofrequency ablation for large uterine fibroids.
Topics: Female; Humans; Leiomyoma; Mifepristone; Quality of Life; Radiofrequency Ablation; Retrospective Studies; Treatment Outcome; Uterine Neoplasms | 2021 |
The use of mifepristone in abortion associated with an increased risk of uterine leiomyomas.
Topics: Abortion, Induced; Adult; Case-Control Studies; Dose-Response Relationship, Drug; Educational Status; Female; Humans; Leiomyoma; Logistic Models; Menstruation; Middle Aged; Mifepristone; Multivariate Analysis; Odds Ratio; Parity; Retrospective Studies; Risk Factors; Surveys and Questionnaires; Uterine Neoplasms; Vaginitis; Young Adult | 2017 |
Progesterone receptor antagonist provides palliative effects for uterine leiomyoma through a Bcl-2/Beclin1-dependent mechanism.
Topics: Adult; Apoptosis; Autophagic Cell Death; Beclin-1; Female; Humans; Leiomyoma; Middle Aged; Mifepristone; Palliative Care; Proto-Oncogene Proteins c-bcl-2; Receptors, Progesterone; Uterine Neoplasms | 2019 |
Mifepristone inhibits extracellular matrix formation in uterine leiomyoma.
Topics: Cell Line, Transformed; Dose-Response Relationship, Drug; Extracellular Matrix; Female; Hormone Antagonists; Humans; Leiomyoma; Mifepristone; Promegestone; Tumor Cells, Cultured; Uterine Neoplasms | 2016 |
Medical abortion in women with large uterine fibroids: a case series.
Topics: Abortifacient Agents; Abortion, Induced; Administration, Intravaginal; Adult; Drug Administration Schedule; Female; Gestational Age; Humans; Leiomyoma; Maryland; Mifepristone; Misoprostol; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Trimester, First; Pregnancy Trimester, Second; Uterine Neoplasms | 2016 |
Ovarian steroid hormones modulate the expression of progesterone receptors and histone acetylation patterns in uterine leiomyoma cells.
Topics: Adult; Cells, Cultured; Estradiol; Estrogens; Female; Gene Expression Regulation, Neoplastic; Histone Acetyltransferases; Histone Deacetylases; Hormone Antagonists; Humans; Leiomyoma; Middle Aged; Mifepristone; Myometrium; Neoplasm Proteins; Progesterone; Progestins; Receptors, Progesterone; Tumor Cells, Cultured; Uterine Neoplasms | 2017 |
CDB-2914 for uterine leiomyomata treatment: a randomized controlled trial.
Topics: Female; Hormone Antagonists; Humans; Leiomyoma; Mifepristone; Norpregnadienes; Quality of Life; Randomized Controlled Trials as Topic; Uterine Neoplasms | 2008 |
Progestins activate the AKT pathway in leiomyoma cells and promote survival.
Topics: Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Survival; Female; Fluorescent Antibody Technique; Forkhead Box Protein O1; Forkhead Transcription Factors; Humans; Leiomyoma; Mifepristone; Oncogene Protein v-akt; Phosphorylation; Progestins; Promegestone; Signal Transduction; Uterine Neoplasms | 2009 |
Mifepristone for the treatment of uterine leiomyomas: methodological issues and clinical implications.
Topics: Female; Hormone Antagonists; Humans; Leiomyoma; Mifepristone; Organ Size; Uterine Neoplasms; Uterus | 2009 |
Re: Low-dose mifepristone: Effects on the endometrium. Aust N Z J Obstet Gynaecol 2009; 49: 77-83.
Topics: Endometrium; Female; Hormone Antagonists; Humans; Leiomyoma; Menorrhagia; Mifepristone; Uterine Neoplasms | 2009 |
Progesterone and mifepristone regulate L-type amino acid transporter 2 and 4F2 heavy chain expression in uterine leiomyoma cells.
Topics: Adult; Amino Acid Transport System y+; Cell Survival; DNA Primers; Female; Follicular Phase; Fusion Regulatory Protein 1, Heavy Chain; Fusion Regulatory Protein 1, Light Chains; Gene Expression Regulation, Neoplastic; Humans; Leiomyoma; Luteal Phase; Menstruation; Middle Aged; Mifepristone; Polymerase Chain Reaction; Progesterone; RNA, Messenger; RNA, Neoplasm; RNA, Small Interfering; Uterine Neoplasms | 2009 |
Transcription factor KLF11 integrates progesterone receptor signaling and proliferation in uterine leiomyoma cells.
Topics: Apoptosis Regulatory Proteins; Cell Cycle Proteins; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Hormone Antagonists; Humans; Leiomyoma; Mifepristone; Progesterone; Promoter Regions, Genetic; Receptors, Progesterone; Repressor Proteins; Signal Transduction; Trans-Activators; Transcription Factors; Tumor Burden; Tumor Cells, Cultured; Uterine Neoplasms | 2010 |
Improved quality of life is partly explained by fewer symptoms after treatment of fibroids with mifepristone.
Topics: Adult; Anemia; Female; Hormone Antagonists; Humans; Leiomyoma; Middle Aged; Mifepristone; Organ Size; Pain; Quality of Life; Randomized Controlled Trials as Topic; Ultrasonography; Uterine Neoplasms; Uterus | 2010 |
Progesterone is essential for maintenance and growth of uterine leiomyoma.
Topics: Animals; Estradiol; Estrogen Receptor alpha; Female; Humans; Immunohistochemistry; In Situ Nick-End Labeling; In Vitro Techniques; Leiomyoma; Mice; Mifepristone; Myometrium; Progesterone; Receptors, Progesterone; Transplantation, Heterologous; Uterine Neoplasms | 2010 |
LAT1 regulates growth of uterine leiomyoma smooth muscle cells.
Topics: Adult; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Female; Hormone Antagonists; Humans; Large Neutral Amino Acid-Transporter 1; Leiomyoma; Middle Aged; Mifepristone; Myocytes, Smooth Muscle; Myometrium; Progesterone; RNA Interference; RNA, Messenger; Uterine Neoplasms | 2010 |
Distinguishing features of endometrial pathology after exposure to the progesterone receptor modulator mifepristone.
Topics: Adult; Endometrium; Female; Hormone Antagonists; Humans; Leiomyoma; Middle Aged; Mifepristone; Receptors, Progesterone; Uterine Neoplasms | 2011 |
Genome-wide progesterone receptor binding: cell type-specific and shared mechanisms in T47D breast cancer cells and primary leiomyoma cells.
Topics: Adult; Base Sequence; Binding Sites; Breast Neoplasms; Cell Line, Tumor; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genome, Human; Hormone Antagonists; Humans; Leiomyoma; Membrane Proteins; Middle Aged; Mifepristone; Nucleotide Motifs; Oligonucleotide Array Sequence Analysis; Perilipin-2; Position-Specific Scoring Matrices; Receptors, Progesterone; Response Elements; Tumor Cells, Cultured; Uterine Neoplasms | 2012 |
Pharmacokinetic evaluation of ulipristal acetate for uterine leiomyoma treatment.
Topics: Adult; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Drug Evaluation, Preclinical; Female; Hormone Antagonists; Humans; Leiomyoma; Menorrhagia; Mifepristone; Norpregnadienes; Progesterone; Receptors, Progesterone; Uterine Neoplasms | 2012 |
RU486 inhibits expression of lysophosphatidic acid induced glycodelin.
Topics: Adult; Base Sequence; Biopsy, Needle; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation, Neoplastic; Glycoproteins; Humans; Immunohistochemistry; Leiomyoma; Lysophospholipids; Middle Aged; Mifepristone; Molecular Sequence Data; Probability; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; Sensitivity and Specificity; Tumor Cells, Cultured; Uterine Neoplasms | 2005 |
[Effects of estrogen, progestin and mifepristone on endometrial carcinoma cell lines].
Topics: Cell Line, Tumor; Cell Proliferation; Endometrial Neoplasms; Estradiol; Female; Humans; Mifepristone; Progesterone; Uterine Neoplasms | 2005 |
Progesterone regulates HLA-G gene expression through a novel progesterone response element.
Topics: Breast Neoplasms; Cell Line; Cell Line, Tumor; Choriocarcinoma; DNA Primers; Female; Gene Expression Regulation; Genes, Reporter; Histocompatibility Antigens Class I; HLA Antigens; HLA-G Antigens; Humans; Mifepristone; Pregnancy; Progesterone; Promoter Regions, Genetic; Receptors, Progesterone; Uterine Neoplasms | 2006 |
Mifepristone as treatment of recurrent progesterone receptor-positive uterine leiomyosarcoma.
Topics: Diagnosis, Differential; Female; Hormone Antagonists; Humans; Leiomyosarcoma; Middle Aged; Mifepristone; Neoplasm Recurrence, Local; Neoplasm Staging; Radiography; Receptors, Progesterone; Uterine Neoplasms | 2007 |
Progesterone receptor (PR) isoforms PRA and PRB differentially regulate expression of the breast cancer resistance protein in human placental choriocarcinoma BeWo cells.
Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line, Tumor; Choriocarcinoma; Dose-Response Relationship, Drug; Female; Gene Deletion; Gene Expression Regulation, Neoplastic; Humans; Luciferases; Mifepristone; Mutation; Neoplasm Proteins; Placenta; Pregnancy; Progesterone; Promoter Regions, Genetic; Protein Isoforms; Receptors, Progesterone; Response Elements; Statistics as Topic; Transcription, Genetic; Transfection; Uterine Neoplasms | 2008 |
Termination of a molar pregnancy using mifepristone and gemeprost.
Topics: Abortifacient Agents, Nonsteroidal; Abortion, Induced; Adult; Alprostadil; Female; Humans; Hydatidiform Mole; Mifepristone; Pregnancy; Uterine Neoplasms | 1994 |
The regulation of fibroid growth: time for a re-think?
Topics: Estradiol; Female; Gonadotropin-Releasing Hormone; Humans; Leiomyoma; Mifepristone; Pregnancy; Progesterone; Uterine Neoplasms | 1993 |
[The use of sulprostone (Nalador) in the evacuation of uterine contents. Apropos of 32 cases at the Department of Gynecology, University Hospital Center, Nîmes, over 2 years (a retrospective study)].
Topics: Abortifacient Agents, Nonsteroidal; Abortion, Induced; Adolescent; Adult; Cicatrix; Contraindications; Dinoprostone; Drug Tolerance; Female; France; Gestational Age; Humans; Hydatidiform Mole; Infusions, Intravenous; Injections, Intramuscular; Injections, Intravenous; Mifepristone; Misoprostol; Polyhydramnios; Pregnancy; Retrospective Studies; Time Factors; Uterine Diseases; Uterine Neoplasms | 1993 |
Regression of uterine leiomyomata in response to the antiprogesterone RU 486.
Topics: Adolescent; Adult; Androstenedione; Bone Density; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Follicle Stimulating Hormone; Humans; Hysterectomy; Immunohistochemistry; Leiomyoma; Luteinizing Hormone; Middle Aged; Mifepristone; Myometrium; Progesterone; Receptors, Estradiol; Receptors, Progesterone; Testosterone; Uterine Neoplasms | 1993 |
Progestin-dependent stimulation of the human leukemia inhibitory factor promoter in SKUT-1B uterine tumor cells.
Topics: Female; Gene Expression Regulation, Neoplastic; Growth Inhibitors; Humans; Interleukin-6; Jurkat Cells; Leukemia Inhibitory Factor; Lymphokines; Medroxyprogesterone Acetate; Mifepristone; Progestins; Promoter Regions, Genetic; Receptors, Progesterone; RNA, Messenger; Sequence Deletion; Transfection; Tumor Cells, Cultured; Uterine Neoplasms | 1997 |
Tamoxifen-mediated anti-cellular effect against a choriocarcinoma cell line.
Topics: Cell Line; Cell Survival; Choriocarcinoma; Estrogen Antagonists; Female; Hormone Antagonists; Humans; Kinetics; Mifepristone; Pregnancy; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Trophoblasts; Uterine Neoplasms | 1998 |
[Effect of mifepristone on the expression of progesterone receptor messenger RNA and protein in uterine leiomyomata].
Topics: Adult; Female; Gene Expression; Humans; Leiomyoma; Middle Aged; Mifepristone; Receptors, Progesterone; RNA, Messenger; Uterine Neoplasms | 1998 |
Gestational trophoblastic disease: a study of mode of evacuation and subsequent need for treatment with chemotherapy.
Topics: Abortifacient Agents, Steroidal; Dilatation and Curettage; Female; Humans; Hydatidiform Mole; Mifepristone; Oxytocin; Pregnancy; Prostaglandins; Retrospective Studies; Uterine Neoplasms; Vacuum Curettage | 2000 |
Effects of mifepristone (RU486) treatment on the development of uterine adenomyosis induced by pituitary grafting in mice.
Topics: Adenomyoma; Animals; Anticarcinogenic Agents; Endometrium; Female; Mice; Mice, Inbred Strains; Mifepristone; Organ Size; Pituitary Gland; Receptors, Progesterone; Stromal Cells; Uterine Neoplasms; Uterus; von Willebrand Factor | 2000 |
[Clinical application of mifepristone in obstetrics and gynecology].
Topics: Abortifacient Agents, Steroidal; Contraceptives, Postcoital, Synthetic; Endometriosis; Female; Humans; Leiomyoma; Mifepristone; Pregnancy; Uterine Neoplasms | 1999 |
[National symposium on clinical application of mifepristone in obstetrics and gynecology].
Topics: Abortifacient Agents, Steroidal; Contraceptives, Postcoital, Synthetic; Female; Humans; Mifepristone; Pregnancy; Pregnancy, Ectopic; Uterine Neoplasms | 1999 |
[Effects of mifepristone on choriocarcinoma cell line JAR in vitro].
Topics: Cell Division; Choriocarcinoma; Chorionic Gonadotropin; Female; Humans; Ki-67 Antigen; Mifepristone; Pregnancy; Tumor Cells, Cultured; Uterine Neoplasms | 1999 |
[Effects of mifepristone on estrogen and progestin receptors in human uterine leiomyoma].
Topics: Adult; Female; Hormone Antagonists; Humans; Leiomyoma; Middle Aged; Mifepristone; Receptors, Estrogen; Receptors, Progesterone; Uterine Neoplasms | 2000 |
Effect of mifepristone on estrogen and progesterone receptors in human endometrial and endometriotic cells in vitro.
Topics: Adult; Cells, Cultured; Dose-Response Relationship, Drug; Down-Regulation; Endometriosis; Endometrium; Female; Follicular Phase; Hormone Antagonists; Humans; Immunohistochemistry; Leiomyoma; Luteal Phase; Mifepristone; Osmolar Concentration; Prospective Studies; Receptors, Estrogen; Receptors, Progesterone; Uterine Neoplasms | 2002 |
The biological effects of macrophage-colony-stimulating factor induced by progestin on growth and differentiation of endometrial adenocarcinoma cells.
Topics: Adenocarcinoma; Cell Differentiation; Female; Genes, fms; Humans; Macrophage Colony-Stimulating Factor; Mifepristone; Progestins; Receptor, Macrophage Colony-Stimulating Factor; RNA, Messenger; Tumor Cells, Cultured; Uterine Neoplasms | 1991 |
Progesterone dependence and extratrophoblastic origin of pregnancy-associated plasma protein-A (PAPP-A) in early pregnancy.
Topics: Abortifacient Agents, Steroidal; Abortion, Habitual; Abortion, Induced; Adolescent; Adult; Chorionic Gonadotropin; Culture Techniques; Decidua; Estrenes; Female; Humans; Hydatidiform Mole; Middle Aged; Mifepristone; Pregnancy; Pregnancy Proteins; Pregnancy Trimester, First; Pregnancy-Associated Plasma Protein-A; Progesterone; Prolactin; Trophoblasts; Uterine Neoplasms | 1986 |
RU486, a progestin antagonist, binds to progesterone receptors in a human endometrial cancer cell line and reverses the growth inhibition by progestins.
Topics: Binding, Competitive; Cell Division; Cellulose; Cytoplasm; DNA; Estrenes; Female; Glycogen; Humans; Mifepristone; Periodic Acid-Schiff Reaction; Progestins; Promegestone; Receptors, Progesterone; Staining and Labeling; Tumor Cells, Cultured; Uterine Neoplasms | 1988 |
Mechanism of antitumoral activity of medroxyprogesterone acetate for endometrial cancer.
Topics: Antineoplastic Agents; Female; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Mifepristone; Norethindrone; Receptors, Progesterone; Tumor Cells, Cultured; Tumor Stem Cell Assay; Uterine Neoplasms | 1989 |
[Progestogen therapy in the treatment of endometrial cancer--clinical results and mechanism of steroid action].
Topics: Estrenes; Female; Humans; In Vitro Techniques; Medroxyprogesterone; Medroxyprogesterone Acetate; Mifepristone; Neoplasms, Hormone-Dependent; Norethindrone; Norgestrel; Progesterone Congeners; Receptors, Progesterone; Tumor Stem Cell Assay; Uterine Neoplasms | 1988 |