mifepristone has been researched along with Obesity in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (37.14) | 18.2507 |
| 2000's | 8 (22.86) | 29.6817 |
| 2010's | 12 (34.29) | 24.3611 |
| 2020's | 2 (5.71) | 2.80 |
| Authors | Studies |
|---|---|
| Abd Jamil, AH; Chung, I; Mat Adenan, NA; Omar, IS | 1 |
| Andrews, ZB; Cowley, MA; Dodd, GT; Eramo, M; Henry, BA; Mitchell, CA; Tiganis, T; Xirouchaki, CE | 1 |
| Grewal, S; Gubbi, S; McGlotten, R; Muniyappa, R; Nieman, LK; Sharma, ST | 1 |
| Chuan, K; Du, SF; He, ZJ; Liu, SJ; Liu, YJ; Ye, CL; Yu, Q; Zhu, XY | 1 |
| Hunt, H; Koorneef, LL; Kroon, J; Meijer, OC; Mol, IM; Rensen, PCN; Sips, HCM; van de Velde, NM; van den Heuvel, JK; Verzijl, CRC | 1 |
| Athimulam, S; Bancos, I; Delivanis, DA | 1 |
| Hasan, AU; Hashimoto, T; Igarashi, J; Kohno, M; Kosaka, H; Nagai, Y; Ohmori, K; Yamashita, T | 1 |
| Akiyama, N; Akiyama, Y; Asakura, K; Hanasaki, K; Imagawa, K; Kato, H; Kuroda, T; Murayama, T; Ono, T; Shinosaki, T | 1 |
| Badurek, S; Brönneke, HS; Geibel, M; Horn, JM; Koudelka, J; Minichiello, L; Vatanashevanopakorn, C; Wunderlich, CM; Wunderlich, FT | 1 |
| Howland, RH | 1 |
| Creinin, MD; Monmaney, JA; Reeves, MF | 1 |
| Belanoff, JK; Boon, MR; Hunt, H; Meijer, OC; Pereira, AM; Peschier-van der Put, E; Rensen, PC; van Beek, L; van den Heuvel, JK; van Dijk, KW; van Harmelen, V; van Hengel, I | 1 |
| Borgatta, L; Mottl-Santiago, J; Savla, A; Soodoo, N; Strafford, MA | 1 |
| Mattsson, C; Olsson, T; Reynolds, RM; Simonyte, K; Walker, BR | 1 |
| Campbell, JE; Fediuc, S; Hawke, TJ; Riddell, MC | 1 |
| Flatt, PR; Frizzell, N; Gault, VA; McKillop, AM; Taylor, AI | 1 |
| Funahashi, T; Hirata, A; Hiuge-Shimizu, A; Maeda, N; Nakatsuji, H; Okada, T; Shimomura, I | 1 |
| Batur, P | 1 |
| Chekhranova, MK; Iatsyshina, SB; Karpova, SK; Morozova, MS; Pankov, IuA; Sazina, ET; Zaĭtseva, TS | 1 |
| Andrew, R; Homer, NZ; Karpe, F; Stimson, RH; Tan, GD; Wake, DJ; Walker, BR | 1 |
| Bruch, D; Harb, G; Kieffer, TJ; Korbutt, GS; Lam, AW; Lam, NT; Oosman, SN; Unniappan, S; Webber, T; Zhang, QX | 1 |
| Clifton, LG; Lin, P; McNulty, JA; Pahel, GL; Shen, Y; Stimpson, SA; Trump, RP; Yang, B | 1 |
| Heikinheimo, O; Huupponen, R; Koulu, M; Lähteenmäki, P; Pesonen, U | 1 |
| Alam, T; Chen, L; McCorkle, K; McGarry, JD; Ogawa, A; Ohneda, M; Pieber, TR; Stein, DT; Unger, RH | 1 |
| Chen, HL; Romsos, DR | 1 |
| Altemus, M; Castonguay, TW; Kramlik, SK | 1 |
| Busch, BL; Curry, DL; Dallman, MF; Havel, PJ; Johnson, PR; Stern, JS | 1 |
| Clapham, JC; Turner, NC | 1 |
| Koulu, M; Miettinen, T; Pesonen, U; Scheinin, M | 1 |
| Huupponen, R; Jolkkonen, J; Koulu, M; Pesonen, U | 1 |
| Heikinheimo, O; Huupponen, R; Koulu, M; Pesonen, U | 1 |
| Bray, GA; Okada, S; York, DA | 1 |
| Huupponen, R; Koulu, M; Pesonen, U; Rouru, J | 1 |
| Dubuc, PU; Peterson, CM | 1 |
| Langley, SC; York, DA | 1 |
1 review(s) available for mifepristone and Obesity
| Article | Year |
|---|---|
Emergency contraception: separating fact from fiction.
Topics: Abortion, Induced; Contraception, Postcoital; Counseling; Crime Victims; Female; Hospitals; Humans; Intrauterine Devices, Copper; Levonorgestrel; Mifepristone; Nonprescription Drugs; Norpregnadienes; Obesity; Practice Patterns, Physicians'; Pregnancy; Pregnancy, Unplanned; Sex Offenses; United States | 2012 |
5 trial(s) available for mifepristone and Obesity
| Article | Year |
|---|---|
Mifepristone Improves Adipose Tissue Insulin Sensitivity in Insulin Resistant Individuals.
Topics: Adipose Tissue; Adult; Aged; Cross-Over Studies; Double-Blind Method; Female; Glucose Intolerance; Humans; Insulin Resistance; Insulin Secretion; Male; Middle Aged; Mifepristone; Obesity; Overweight; Prediabetic State; United States | 2021 |
Predictors of uterine evacuation following early medical abortion with mifepristone and misoprostol.
Topics: Abortifacient Agents; Abortifacient Agents, Nonsteroidal; Abortifacient Agents, Steroidal; Abortion, Incomplete; Abortion, Induced; Adult; Age Factors; Female; Gestational Age; Humans; Mifepristone; Misoprostol; Obesity; Parity; Pregnancy; Suction; Uterus | 2016 |
Combined receptor antagonist stimulation of the hypothalamic-pituitary-adrenal axis test identifies impaired negative feedback sensitivity to cortisol in obese men.
Topics: Adult; Blood Pressure; Cross-Over Studies; Double-Blind Method; Feedback; Female; Hormone Antagonists; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Middle Aged; Mifepristone; Mineralocorticoid Receptor Antagonists; Obesity; Overweight; Pituitary-Adrenal System; Placebos; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone; Waist-Hip Ratio | 2009 |
Effects of peroxisome proliferator-activated receptor-alpha and -gamma agonists on 11beta-hydroxysteroid dehydrogenase type 1 in subcutaneous adipose tissue in men.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adult; Aged; Cortisone; Cross-Over Studies; Double-Blind Method; Enzyme Inhibitors; Fenofibrate; Gas Chromatography-Mass Spectrometry; Hormone Antagonists; Humans; Hydrocortisone; Hypolipidemic Agents; Insulin Resistance; Kinetics; Liver; Male; Metyrapone; Microdialysis; Middle Aged; Mifepristone; Obesity; PPAR alpha; PPAR gamma; Rosiglitazone; Subcutaneous Fat; Thiazolidinediones | 2007 |
The effects of the acute administration of RU 486 on dietary fat preference in fasted lean and obese men.
Topics: Adrenocorticotropic Hormone; Adult; Blood Glucose; Dietary Fats; Double-Blind Method; Energy Intake; Energy Metabolism; Fasting; Food Preferences; Humans; Hydrocortisone; Insulin; Male; Mifepristone; Obesity; Receptors, Glucocorticoid | 1993 |
29 other study(ies) available for mifepristone and Obesity
| Article | Year |
|---|---|
MPA alters metabolic phenotype of endometrial cancer-associated fibroblasts from obese women via IRS2 signaling.
Topics: Acetates; Cancer-Associated Fibroblasts; Endometrial Neoplasms; Female; Glucose; Humans; Insulin Receptor Substrate Proteins; Medroxyprogesterone Acetate; Mifepristone; Neoplasm Recurrence, Local; Obesity; Phenotype; Progesterone; Receptors, Progesterone; RNA, Messenger | 2022 |
Intranasal Targeting of Hypothalamic PTP1B and TCPTP Reinstates Leptin and Insulin Sensitivity and Promotes Weight Loss in Obesity.
Topics: Adipose Tissue, White; Administration, Intranasal; Animals; Blood-Brain Barrier; Cholestanes; Diet, High-Fat; Feeding Behavior; Gliosis; Glucocorticoids; Hypothalamus; Insulin Resistance; Leptin; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mifepristone; Obesity; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatase, Non-Receptor Type 2; Spermine; Weight Loss | 2019 |
In obese mice, exercise training increases 11β-HSD1 expression, contributing to glucocorticoid activation and suppression of pulmonary inflammation.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; 3-Hydroxysteroid Dehydrogenases; Animals; Chemokine CCL2; Cholesterol Side-Chain Cleavage Enzyme; Cytochrome P450 Family 21; Glucocorticoids; Interleukin-18; Interleukin-1beta; Lung; Mice, Obese; Mifepristone; Obesity; Physical Conditioning, Animal; Pneumonia; Steroid 11-beta-Hydroxylase | 2017 |
Selective Glucocorticoid Receptor Antagonist CORT125281 Activates Brown Adipose Tissue and Alters Lipid Distribution in Male Mice.
Topics: Adipocytes, Brown; Adiposity; Adrenal Glands; Animals; Anti-Obesity Agents; Cells, Cultured; Corticosterone; Dose-Response Relationship, Drug; HEK293 Cells; Hormone Antagonists; Humans; Lipid Metabolism; Liver; Male; Mice, Inbred C57BL; Mifepristone; Obesity; Organ Size; Receptors, Glucocorticoid; Recombinant Proteins; Weight Gain | 2018 |
Modern Management of Mild Autonomous Cortisol Secretion.
Topics: 14-alpha Demethylase Inhibitors; Adrenal Cortex Neoplasms; Adrenal Insufficiency; Adrenalectomy; Adrenocortical Adenoma; Adrenocorticotropic Hormone; Dehydroepiandrosterone Sulfate; Diabetes Mellitus, Type 2; Disease Management; Dyslipidemias; Enzyme Inhibitors; Glucocorticoids; Hormone Antagonists; Humans; Hydrocortisone; Hypertension; Incidental Findings; Ketoconazole; Metyrapone; Mifepristone; Mortality; Obesity; Osteoporosis; Postoperative Hemorrhage; Risk; Saliva; Severity of Illness Index | 2019 |
Mifepristone promotes adiponectin production and improves insulin sensitivity in a mouse model of diet-induced-obesity.
Topics: 3T3-L1 Cells; Adiponectin; Adipose Tissue; Animals; Cell Differentiation; Diet, High-Fat; Disease Models, Animal; Insulin Resistance; Male; Mice; Mifepristone; Obesity | 2013 |
Pharmacological evaluation of adipose dysfunction via 11β-hydroxysteroid dehydrogenase type 1 in the development of diabetes in diet-induced obese mice with cortisone pellet implantation.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipose Tissue; Animals; Cortisone; Diabetes Mellitus, Experimental; Diet, High-Fat; Glucocorticoids; Glucose; Insulin Resistance; Mice; Mice, Inbred C57BL; Mifepristone; Obesity; Receptors, Glucocorticoid; Up-Regulation | 2014 |
Ablation of TrkB signalling in CCK neurons results in hypercortisolism and obesity.
Topics: Animals; Body Composition; Calorimetry, Indirect; Cholecystokinin; Cushing Syndrome; Eating; Female; GABAergic Neurons; Immunoblotting; In Situ Hybridization; Male; Membrane Glycoproteins; Mice; Mifepristone; Obesity; Protein-Tyrosine Kinases | 2014 |
Odds and ends in psychopharmacology from the past 10 years.
Topics: Acetamides; Anti-Obesity Agents; Antidepressive Agents; Central Nervous System Stimulants; Depression; Electroencephalography; History, 21st Century; Humans; Mifepristone; Obesity; Psychopharmacology; Stereoisomerism | 2015 |
Identification of a selective glucocorticoid receptor modulator that prevents both diet-induced obesity and inflammation.
Topics: Animals; Body Weight; Diet, High-Fat; Inflammation; Male; Mice; Mice, Inbred C57BL; Mifepristone; Obesity; RAW 264.7 Cells; Receptors, Glucocorticoid | 2016 |
Relationship of obesity to outcome of medical abortion.
Topics: Abortifacient Agents, Steroidal; Abortion, Induced; Adult; Body Mass Index; Female; Humans; Mifepristone; Obesity; Pregnancy; Retrospective Studies; Risk Factors; Treatment Outcome; Young Adult | 2009 |
Endurance exercise training increases adipose tissue glucocorticoid exposure: adaptations that facilitate lipolysis.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 3T3-L1 Cells; Adipose Tissue; Animals; Blood Glucose; Cricetinae; Glucocorticoids; Glucose Tolerance Test; Hormone Antagonists; Immunoblotting; Insulin; Lipolysis; Male; Mesocricetus; Mice; Mifepristone; Obesity; Physical Conditioning, Animal; Random Allocation; Receptors, Glucocorticoid | 2009 |
Effect of RU486 on hepatic and adipocyte gene expression improves diabetes control in obesity-type 2 diabetes.
Topics: Adipocytes; Adipose Tissue, White; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Drug Administration Schedule; Epididymis; Fasting; Feeding Behavior; Gene Expression Regulation; Glucose Tolerance Test; Insulin; Liver; Male; Mice; Mice, Obese; Mifepristone; Obesity; Pancreas; RNA, Messenger; Triglycerides | 2009 |
Contribution of glucocorticoid-mineralocorticoid receptor pathway on the obesity-related adipocyte dysfunction.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 3T3-L1 Cells; Adipocytes; Adipokines; Animals; Body Mass Index; Eplerenone; Glucocorticoids; Humans; Male; Metabolic Networks and Pathways; Mice; Mice, Mutant Strains; Mifepristone; Mineralocorticoid Receptor Antagonists; Obesity; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; RNA, Small Interfering; Spironolactone | 2012 |
[Molecular and genetic study of the role of hormones, receptors, and enzymes in regulation of reproduction, lipid metabolism, and other human physiological functions].
Topics: Abortifacient Agents, Steroidal; Abortion, Induced; Abortion, Spontaneous; Animals; Appetite; beta-Lipotropin; Cattle; Diabetes Mellitus, Type 1; Female; Genetic Engineering; Glutamate Decarboxylase; Humans; Leptin; Lipid Metabolism; Male; Mifepristone; Mutation; Obesity; Pregnancy; Receptors, Estrogen; Receptors, Melanocortin; Receptors, Progesterone; Reproduction; Research; RNA, Messenger; Sterol Esterase; Swine; Uterus | 2005 |
Treatment of obesity and diabetes in mice by transplant of gut cells engineered to produce leptin.
Topics: Adipose Tissue; Animals; Body Weight; Cell Transplantation; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Insulin; Kidney; Leptin; Mice; Mice, Obese; Mifepristone; Obesity; RNA, Messenger; Transfection | 2008 |
RU486 did not exacerbate cytokine release in mice challenged with LPS nor in db/db mice.
Topics: Adrenocorticotropic Hormone; Animals; Blood Glucose; Chemokine CCL2; Corticosterone; Diabetes Mellitus, Type 2; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Glucose-6-Phosphatase; Hormone Antagonists; Hypoglycemic Agents; Interleukin-6; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mifepristone; Obesity; Protein Serine-Threonine Kinases; Receptors, Glucocorticoid; Receptors, Leptin; Tumor Necrosis Factor-alpha | 2008 |
Hepatic metabolism and distribution of mifepristone and its metabolites in rats.
Topics: Administration, Oral; Animals; Biotransformation; Body Mass Index; Female; Half-Life; Humans; Hydroxylation; Liver; Male; Methylation; Mifepristone; Obesity; Rats; Rats, Wistar; Rats, Zucker; Species Specificity; Tissue Distribution | 1994 |
Amylin-insulin relationships in insulin resistance with and without diabetic hyperglycemia.
Topics: Amyloid; Animals; Dexamethasone; Diabetes Mellitus, Type 2; Hyperglycemia; Insulin; Insulin Resistance; Insulin Secretion; Islet Amyloid Polypeptide; Male; Mifepristone; Obesity; Pancreas; Rats; Rats, Wistar; Rats, Zucker; Receptors, Glucocorticoid; RNA, Messenger; Somatostatin | 1993 |
Type II glucocorticoid receptors in the CNS regulate metabolism in ob/ob mice independent of protein synthesis.
Topics: Adipose Tissue, Brown; Adrenalectomy; Animals; Anisomycin; Brain; Dexamethasone; Guanosine Diphosphate; Insulin; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mifepristone; Obesity; Oxygen Consumption; Protein Biosynthesis; Receptors, Glucocorticoid | 1994 |
Predominately glucocorticoid agonist actions of RU-486 in young specific-pathogen-free Zucker rats.
Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Animals, Newborn; Blood Glucose; Body Weight; Eating; Female; Germ-Free Life; Glucocorticoids; Hormone Antagonists; Hormones; Male; Mifepristone; Obesity; Organ Size; Rats; Rats, Zucker; Reference Values | 1996 |
Effects of the glucocorticoid II receptor antagonist mifepristone on hypertension in the obese Zucker rat.
Topics: Aldosterone; Animals; Blood Pressure; Corticosterone; Hypertension; Male; Mifepristone; Obesity; Rats; Rats, Zucker; Receptors, Glucocorticoid | 1997 |
Alpha 2-adrenoceptor density in forebrain areas of Zucker rats: no effect of genetic obesity or antiglucocorticoid treatment.
Topics: Animals; Glucocorticoids; Iodine Radioisotopes; Male; Mifepristone; Obesity; Prosencephalon; Radioligand Assay; Rats; Rats, Zucker; Receptors, Adrenergic, alpha | 1992 |
Differential hypothalamic arginine vasopressin response to glucocorticoid receptor antagonism in lean and obese Zucker rats.
Topics: Animals; Arginine Vasopressin; Corticosterone; Hypothalamus; In Situ Hybridization; Male; Median Eminence; Mifepristone; Obesity; Pituitary Gland; Rats; Rats, Zucker; Receptors, Glucocorticoid; RNA, Messenger | 1992 |
The glucocorticoid antagonist mifepristone reveals abnormal regulation of the adrenocortical system in obese Zucker rats.
Topics: Animals; Corticosterone; Corticotropin-Releasing Hormone; Hypothalamo-Hypophyseal System; Male; Mifepristone; Obesity; Pituitary-Adrenal System; Pro-Opiomelanocortin; Protein Precursors; Rats; Rats, Zucker; Receptors, Glucocorticoid; RNA, Messenger | 1992 |
Mifepristone (RU 486), a blocker of type II glucocorticoid and progestin receptors, reverses a dietary form of obesity.
Topics: Animals; Corticosterone; Dietary Fats; Female; Mifepristone; Obesity; Rats; Rats, Mutant Strains; Receptors, Glucocorticoid; Receptors, Progesterone | 1992 |
Effects of repeated administration of mifepristone and 8-OH-DPAT on expression of preproneuropeptide Y mRNA in the arcuate nucleus of obese Zucker rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Arcuate Nucleus of Hypothalamus; Corticosterone; Gene Expression; Insulin; Male; Mifepristone; Neuropeptide Y; Nucleic Acid Hybridization; Obesity; Protein Precursors; Rats; Rats, Zucker; Reference Values; RNA, Messenger; Tetrahydronaphthalenes | 1991 |
Ineffectiveness of parenteral fluoxetine or RU-486 to alter long-term food intake, body weight or body composition of genetically obese mice.
Topics: Animals; Body Composition; Body Weight; Drug Administration Schedule; Eating; Female; Fluoxetine; Injections, Subcutaneous; Male; Mice; Mice, Obese; Mifepristone; Obesity; Parenteral Nutrition; Time Factors | 1990 |
Effects of antiglucocorticoid RU 486 on development of obesity in obese fa/fa Zucker rats.
Topics: Animals; Body Composition; Body Weight; Brain; Corticosterone; Eating; Female; Glucocorticoids; Insulin; Mifepristone; Obesity; Organ Size; Rats; Rats, Zucker | 1990 |