Page last updated: 2024-08-23

mifepristone and Neoplasms

mifepristone has been researched along with Neoplasms in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (33.33)18.2507
2000's4 (16.67)29.6817
2010's7 (29.17)24.3611
2020's5 (20.83)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Check, DL; Check, JH2
Check, D; Check, JH2
Chung, I; Godoy, A; Gunasagran, Y; Mat Adenan, NA; Omar, IS; Teo, IH1
Ambrosini, G; Andrisani, A; Bordin, L; Conley, J; Marin, L; Sabbadin, C; Vio, C1
Li, CJ; Pardee, AB1
Brandhagen, BN; Goyeneche, AA; Ritch, SJ; Telleria, CM1
Check, D; Check, JH; Lofberg, P; Wilson, C1
Check, JH; Dix, E; Sansoucie, L1
Check, D; Check, JH; Cohen, R; Dix, E; Wilson, C1
Brandhagen, BN; Goyeneche, AA; Ortbahn, CT; Telleria, CM; Tieszen, CR1
Brandhagen, BN; Goyeneche, AA; Telleria, CM; Tieszen, CR; Tracy, MS; Ulmer, TM1
Watanabe, ME1
Case, CC; Dent, CL; Drake, EA; Gregory, PD; Lau, G; Yoon, A1
Peyron, R; Silvestre, L; Ulmann, A1
Bardin, CW; Spitz, IM1
Grunberg, SM1
Kalkhoven, E; van der Burg, B; van der Saag, PT; Wissink, S1
Bjørge, L; Iversen, OE1

Reviews

8 review(s) available for mifepristone and Neoplasms

ArticleYear
A Hypothetical Model Suggesting Some Possible Ways That the Progesterone Receptor May Be Involved in Cancer Proliferation.
    International journal of molecular sciences, 2021, Nov-16, Volume: 22, Issue:22

    Topics: Antineoplastic Agents, Hormonal; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Female; Fetus; Gene Expression Regulation; Hormone Antagonists; Humans; Immune Tolerance; Mifepristone; Neoplasms; Placenta; Pregnancy; Pregnancy Proteins; Receptors, Progesterone; Signal Transduction; Suppressor Factors, Immunologic; Tumor Microenvironment

2021
New Insights as to Why Progesterone Receptor Modulators, such as Mifepristone, Seem to Be More Effective in Treating Cancers that Are Devoid of the Classical Nuclear Progesterone Receptor.
    Anticancer research, 2021, Volume: 41, Issue:12

    Topics: Animals; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Cell Proliferation; Clinical Studies as Topic; Disease Models, Animal; Disease Susceptibility; Drug Discovery; Drug Evaluation, Preclinical; Gene Expression Regulation, Neoplastic; Humans; Membrane Proteins; Mifepristone; Molecular Targeted Therapy; Neoplasms; Prognosis; Receptors, Progesterone; Treatment Outcome

2021
The role of progesterone and the progesterone receptor in cancer: progress in the last 5 years.
    Expert review of endocrinology & metabolism, 2023, Volume: 18, Issue:1

    Topics: Humans; Mifepristone; Neoplasms; Progesterone; Receptors, Progesterone

2023
Fertility preservation in pregnant cancer patients after first-trimester abortion: a new challenge with possible solutions.
    Journal of assisted reproduction and genetics, 2023, Volume: 40, Issue:12

    Topics: Cryopreservation; Female; Fertility Preservation; Humans; Mifepristone; Neoplasms; Ovulation Induction; Pregnancy; Pregnancy Trimester, First; Progesterone

2023
Therapy Aimed to Suppress the Production of the Immunosuppressive Protein Progesterone Induced Blocking Factor (PIBF) May Provide Palliation and/or Increased Longevity for Patients With a Variety of Different Advanced Cancers - A Review.
    Anticancer research, 2019, Volume: 39, Issue:7

    Topics: Animals; Female; Hormone Antagonists; Humans; Killer Cells, Natural; Longevity; Mifepristone; Neoplasms; Palliative Care; Placenta; Pregnancy; Pregnancy Proteins; Progesterone; Progestins; Receptors, Progesterone; Suppressor Factors, Immunologic

2019
Clinical uses of mifepristone (MFP).
    Annals of the New York Academy of Sciences, 1995, Jun-12, Volume: 761

    Topics: Abortion, Induced; Animals; Cervix Uteri; Clinical Trials as Topic; Contraceptives, Postcoital; Endometriosis; Female; Humans; Hydrocortisone; Labor, Induced; Mifepristone; Misoprostol; Neoplasms; Pregnancy

1995
Clinical pharmacology of RU 486--an antiprogestin and antiglucocorticoid.
    Contraception, 1993, Volume: 48, Issue:5

    Topics: Abortion, Induced; Animals; Female; Genitalia, Female; Glucocorticoids; Humans; Mifepristone; Molecular Structure; Neoplasms; Pregnancy; Progestins

1993
[Mifepristone--a controversial drug with great potential].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2001, Nov-20, Volume: 121, Issue:28

    Topics: Abortifacient Agents, Steroidal; Contraceptives, Oral, Synthetic; Female; Genital Diseases, Female; History, 20th Century; Hormone Antagonists; Humans; Labor, Induced; Mifepristone; Neoplasms; Pregnancy; Pregnancy Complications; Receptors, Progesterone

2001

Other Studies

16 other study(ies) available for mifepristone and Neoplasms

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Aberrant upregulation of CDK1 contributes to medroxyprogesterone acetate (MPA) resistance in cancer-associated fibroblasts of the endometrium.
    Biochemical and biophysical research communications, 2022, 11-05, Volume: 628

    Topics: Cancer-Associated Fibroblasts; CDC2 Protein Kinase; Drug Resistance, Neoplasm; Endometrial Neoplasms; Endometrium; Female; Humans; Luciferases; Medroxyprogesterone Acetate; Mifepristone; Neoplasms; Receptors, Progesterone; RNA, Messenger; Up-Regulation

2022
Two controls of cell proliferation underlie cancer relapse.
    Journal of cellular physiology, 2018, Volume: 233, Issue:11

    Topics: Cell Differentiation; Cell Membrane; Cell Proliferation; Chorionic Gonadotropin; HeLa Cells; Humans; Mifepristone; Mutation; Neoplasms; Neoplastic Stem Cells; Prostaglandins; Recurrence; Signal Transduction; Stem Cells; Zygote

2018
Advanced assessment of migration and invasion of cancer cells in response to mifepristone therapy using double fluorescence cytochemical labeling.
    BMC cancer, 2019, Apr-24, Volume: 19, Issue:1

    Topics: Cell Movement; Cell Proliferation; Fluorescence; Hormone Antagonists; Humans; Mifepristone; Neoplasm Invasiveness; Neoplasms; Tumor Cells, Cultured; Wound Healing

2019
Long-term High-quality Survival with Single-agent Mifepristone Treatment Despite Advanced Cancer.
    Anticancer research, 2016, Volume: 36, Issue:12

    Topics: Aged; Aged, 80 and over; Carcinoma, Renal Cell; Female; Hormone Antagonists; Humans; Kidney Neoplasms; Lung Neoplasms; Male; Middle Aged; Mifepristone; Neoplasms; Survival Rate

2016
Support for the hypothesis that successful immunotherapy of various cancers can be achieved by inhibiting a progesterone associated immunomodulatory protein.
    Medical hypotheses, 2009, Volume: 72, Issue:1

    Topics: Animals; Disease Models, Animal; Humans; Immunologic Factors; Immunotherapy; Lung Neoplasms; Mice; Mifepristone; Neoplasms; Pregnancy Proteins; Progesterone; Receptors, Progesterone; RNA, Messenger; Suppressor Factors, Immunologic

2009
Efficacy of the progesterone receptor antagonist mifepristone for palliative therapy of patients with a variety of advanced cancer types.
    Anticancer research, 2010, Volume: 30, Issue:2

    Topics: Adult; Aged; Carcinoma, Transitional Cell; Colonic Neoplasms; Female; Histiocytoma, Malignant Fibrous; Hormone Antagonists; Humans; Kidney Neoplasms; Leiomyosarcoma; Male; Middle Aged; Mifepristone; Neoplasms; Palliative Care; Pancreatic Neoplasms; Receptors, Progesterone; Survival Rate; Thymus Neoplasms; Treatment Outcome; Young Adult

2010
Antiprogestin mifepristone inhibits the growth of cancer cells of reproductive and non-reproductive origin regardless of progesterone receptor expression.
    BMC cancer, 2011, May-27, Volume: 11

    Topics: Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cytostatic Agents; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Mifepristone; Neoplasms; Receptors, Androgen; Receptors, Estrogen; Receptors, Progesterone

2011
Cytostasis and morphological changes induced by mifepristone in human metastatic cancer cells involve cytoskeletal filamentous actin reorganization and impairment of cell adhesion dynamics.
    BMC cancer, 2013, Jan-26, Volume: 13

    Topics: Actin Cytoskeleton; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cell Shape; Cytostatic Agents; Female; Hormone Antagonists; Humans; Male; Mifepristone; Neoplasm Invasiveness; Neoplasms; Nervous System Neoplasms; Ovarian Neoplasms; Prostatic Neoplasms; Time Factors

2013
RU 486: an overview of mifepristone and its potential applications.
    Contraception Report, 1993, Volume: 4, Issue:2

    Topics: Abortifacient Agents; Abortion, Induced; Americas; Biology; Breast Neoplasms; Contraception; Contraceptive Agents; Contraceptive Agents, Female; Contraceptives, Postcoital; Developed Countries; Disease; Embryo Implantation; Endocrine System; Endometrium; Europe; Family Planning Services; France; Genitalia; Genitalia, Female; Hormone Antagonists; Hormones; Labor Stage, First; Menstruation; Mifepristone; Neoplasms; North America; Ovulation; Physiology; Therapeutics; United States; Urogenital System; Uterus

1993
RU 486 research forges on, despite political hurdles.
    Scientist (Philadelphia, Pa.), 1994, Jan-24, Volume: 8, Issue:2

    Topics: Adrenal Cortex; Americas; Biology; Breast Neoplasms; Central Nervous System; Clinical Trials as Topic; Developed Countries; Disease; Economics; Endocrine Glands; Endocrine System; Evaluation Studies as Topic; Financial Management; Financing, Government; Genitalia; Genitalia, Female; Hormone Antagonists; Hormones; Mifepristone; Neoplasms; North America; Physiology; Politics; Prejudice; Research; Social Problems; United States; Urogenital System; Uterus

1994
RU 486 approved in Britain; U.S. research still limited.
    Contraceptive technology update, 1991, Volume: 12, Issue:9

    Topics: Abortifacient Agents; Abortion, Induced; Americas; Biology; Breast Neoplasms; Consumer Product Safety; Developed Countries; Disease; Endocrine System; Europe; Family Planning Services; France; Hormone Antagonists; Hormones; Legislation as Topic; Mifepristone; Neoplasms; North America; Physiology; Prostaglandins; Scandinavian and Nordic Countries; United Kingdom; United States

1991
Who's trying to scare women?
    SusPop news : the Sustainable Population Society newsletter, 1996, Issue:16

    Topics: Abortion, Induced; Americas; Attitude; Behavior; Biology; Breast Neoplasms; Canada; Contraception; Developed Countries; Disease; Endocrine System; Evaluation Studies as Topic; Family Planning Services; Hormone Antagonists; Hormones; Jurisprudence; Mifepristone; Neoplasms; North America; Physiology; Politics; Psychology; Public Opinion; United States

1996
Regulation of endogenous gene expression using small molecule-controlled engineered zinc-finger protein transcription factors.
    Gene therapy, 2007, Volume: 14, Issue:18

    Topics: Animals; Cell Line; Cell Line, Tumor; Dose-Response Relationship, Drug; Gene Expression; Gene Expression Regulation; Genetic Engineering; Genetic Therapy; Green Fluorescent Proteins; Hormone Antagonists; Humans; Mice; Mifepristone; Neoplasms; Receptors, Progesterone; Time Factors; Transcription Factor RelA; Transcription Factors; Vascular Endothelial Growth Factor A; Zinc Fingers

2007
Methotrexate and misoprostol to terminate early pregnancy.
    The New England journal of medicine, 1996, Feb-08, Volume: 334, Issue:6

    Topics: Abortifacient Agents; Abortion, Induced; Female; Humans; Methotrexate; Mifepristone; Misoprostol; Neoplasms; Pregnancy

1996
Negative interaction between the RelA(p65) subunit of NF-kappaB and the progesterone receptor.
    The Journal of biological chemistry, 1996, Mar-15, Volume: 271, Issue:11

    Topics: Animals; Base Sequence; Cell Line; Cytokines; DNA Primers; Female; Gene Expression Regulation; HeLa Cells; Humans; Immune Tolerance; Mifepristone; Molecular Sequence Data; Neoplasms; NF-kappa B; Phosphorylation; Pregnancy; Pregnancy Maintenance; Progesterone; Progestins; Receptors, Progesterone; Transcription Factor RelA; Tumor Necrosis Factor-alpha

1996