Page last updated: 2024-08-23

mifepristone and Neoplasm Metastasis

mifepristone has been researched along with Neoplasm Metastasis in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.14)18.7374
1990's2 (14.29)18.2507
2000's3 (21.43)29.6817
2010's6 (42.86)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Jia, L; Li, Y; Lu, Y; Xie, H; Zhong, C; Zhou, G1
Check, D; Check, JH; Poretta, T; Wilson, C1
Chen, J; Jia, L; Liu, J; Liu, W; Wang, J; Zheng, N1
Chen, H; Fan, L; Jia, L; Jiang, K; Liu, J; Shao, J; Shen, Z; Zheng, G1
Chen, H; Chen, J; Jia, L; Lu, Y; Ou, M; Shao, J; Wan, L; Wang, J; Yu, S; Zhu, Y1
Chen, J; Gao, Y; Jia, L; Liu, Z; Shao, J; Wang, J; Xu, J; Yu, S1
Dong, H; Gao, Y; Jia, L; Li, T; Lu, Y; Ma, J; Shao, J; Tu, X; Wan, L; Wang, J; Xie, F; Xie, J; Xu, B; Xu, H; Zhang, T; Zhu, Y1
He, S; Huang, C; Jia, L; Liu, J; Lu, Y; Qin, C; Tian, Z; Yan, C; Yang, X; Yu, S1
Check, D; Check, JH; Dix, E; Sansoucie, L1
Abou-Amara-Olivieri, S; Artru, P; Cassier, PA; Lapalus, MG; Lombard-Bohas, C; Riou, JP1
Balk, SP; Barb, D; Bubley, GJ; Gelmann, EP; Kantoff, PW; Manola, J; Mantzoros, C; Oh, WK; Smith, M; Taplin, ME1
Dickson, RB; Lippman, ME; Shi, YE; Sobel, ME; Thompson, EW; Torri, J; Yamada, Y; Yieh, L1
Kimmick, GG; Muss, HB1
Cavalie, G; Grenier, J; Khalaf, S; Maudelonde, T; Pujol, H; Rochefort, H; Romieu, G; Ulmann, A1

Reviews

3 review(s) available for mifepristone and Neoplasm Metastasis

ArticleYear
Similarities and differences between embryonic implantation and CTC invasion: Exploring the roles of abortifacients in cancer metastasis chemoprevention.
    European journal of medicinal chemistry, 2022, Jul-05, Volume: 237

    Topics: Abortifacient Agents; Antineoplastic Agents; Cell Line, Tumor; Chemoprevention; Female; Humans; Male; Mifepristone; Neoplasm Metastasis

2022
The unique pharmacological characteristics of mifepristone (RU486): from terminating pregnancy to preventing cancer metastasis.
    Medicinal research reviews, 2014, Volume: 34, Issue:5

    Topics: Abortifacient Agents, Steroidal; Abortion, Therapeutic; Female; Humans; Liver; Mifepristone; Neoplasm Metastasis; Pregnancy; Pregnancy Complications, Neoplastic

2014
Endocrine therapy in metastatic breast cancer.
    Cancer treatment and research, 1998, Volume: 94

    Topics: Adult; Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estrogen Antagonists; Estrogens; Female; Gonadotropin-Releasing Hormone; Growth Substances; Hormone Antagonists; Humans; Menopause; Middle Aged; Mifepristone; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Palliative Care; Progestins; Receptors, Estrogen; Receptors, Growth Factor; Receptors, Progesterone; Tamoxifen

1998

Trials

2 trial(s) available for mifepristone and Neoplasm Metastasis

ArticleYear
A phase II study of mifepristone (RU-486) in castration-resistant prostate cancer, with a correlative assessment of androgen-related hormones.
    BJU international, 2008, Volume: 101, Issue:9

    Topics: Aged; Aged, 80 and over; Androgens; Antineoplastic Agents, Hormonal; Castration; Cell Communication; Disease Progression; Hormone Antagonists; Humans; Male; Middle Aged; Mifepristone; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Treatment Outcome

2008
The antiprogestin RU486 in advanced breast cancer: preliminary clinical trial.
    Bulletin du cancer, 1987, Volume: 74, Issue:4

    Topics: Breast Neoplasms; Clinical Trials as Topic; Estrenes; Female; Glucocorticoids; Humans; Mifepristone; Neoplasm Metastasis; Time Factors

1987

Other Studies

9 other study(ies) available for mifepristone and Neoplasm Metastasis

ArticleYear
Palliative Benefits of Oral Mifepristone for the Treatment of Metastatic Fibroblastic Osteosarcoma.
    Anticancer research, 2021, Volume: 41, Issue:4

    Topics: Administration, Oral; Bone Neoplasms; Cancer Pain; Humans; Male; Middle Aged; Mifepristone; Neoplasm Metastasis; Osteosarcoma; Palliative Care; Quality of Life; Tibia; Treatment Outcome

2021
Metapristone (RU486 derivative) inhibits cell proliferation and migration as melanoma metastatic chemopreventive agent.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 90

    Topics: Animals; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Down-Regulation; Female; G1 Phase; Melanoma; Mice; Mice, Inbred C57BL; Mifepristone; Neoplasm Metastasis; Resting Phase, Cell Cycle; Signal Transduction; Up-Regulation

2017
Metapristone suppresses non-small cell lung cancer proliferation and metastasis via modulating RAS/RAF/MEK/MAPK signaling pathway.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 90

    Topics: A549 Cells; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Humans; Lung Neoplasms; MAP Kinase Signaling System; Mifepristone; Mitogen-Activated Protein Kinases; Neoplasm Metastasis; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins p21(ras); raf Kinases; Signal Transduction

2017
Synthesis, spectral characterization, and in vitro cellular activities of metapristone, a potential cancer metastatic chemopreventive agent derived from mifepristone (RU486).
    The AAPS journal, 2014, Volume: 16, Issue:2

    Topics: Annexin A5; Anticarcinogenic Agents; Caspase 3; Cell Adhesion; Cell Cycle; Cell Line, Tumor; Chromatography, Liquid; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Membrane Potential, Mitochondrial; Mifepristone; Neoplasm Metastasis; Spectroscopy, Fourier Transform Infrared

2014
Aspirin, lysine, mifepristone and doxycycline combined can effectively and safely prevent and treat cancer metastasis: prevent seeds from gemmating on soil.
    Oncotarget, 2015, Nov-03, Volume: 6, Issue:34

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Doxycycline; Drug Interactions; Female; Human Umbilical Vein Endothelial Cells; Humans; Lysine; Male; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mifepristone; Neoplasm Metastasis; Random Allocation; Rats; Rats, Sprague-Dawley

2015
Pharmacoproteomic analysis reveals that metapristone (RU486 metabolite) intervenes E-cadherin and vimentin to realize cancer metastasis chemoprevention.
    Scientific reports, 2016, Mar-02, Volume: 6

    Topics: Antigens, CD; Blotting, Western; Cadherins; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Shape; Cell Survival; Chemoprevention; Down-Regulation; Epithelial-Mesenchymal Transition; Gene Ontology; Human Umbilical Vein Endothelial Cells; Humans; Isotope Labeling; Metabolome; Mifepristone; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Proteomics; Reproducibility of Results; Up-Regulation; Vimentin

2016
Mifepristone may halt progression of extensively metastatic human adenocarcinoma of the colon - case report.
    Anticancer research, 2009, Volume: 29, Issue:5

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Colonic Neoplasms; Disease Progression; Female; Humans; Male; Middle Aged; Mifepristone; Neoplasm Metastasis; Quality of Life

2009
Mifepristone for ectopic ACTH secretion in metastatic endocrine carcinomas: report of two cases.
    European journal of endocrinology, 2008, Volume: 158, Issue:6

    Topics: ACTH Syndrome, Ectopic; Adult; Carcinoma, Neuroendocrine; Digestive System; Female; Hormone Antagonists; Humans; Hydrocortisone; Middle Aged; Mifepristone; Neoplasm Metastasis; Potassium

2008
Expression of 67 kDa laminin receptor in human breast cancer cells: regulation by progestins.
    Clinical & experimental metastasis, 1993, Volume: 11, Issue:3

    Topics: Analysis of Variance; Animals; Antineoplastic Agents; Basement Membrane; Blotting, Western; Breast Neoplasms; Cell Adhesion; Female; Fibronectins; Humans; Laminin; Mice; Mice, Nude; Mifepristone; Neoplasm Metastasis; Promegestone; Receptors, Laminin; Reproducibility of Results; Tumor Cells, Cultured; Up-Regulation

1993