mifepristone has been researched along with Lung Neoplasms in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (21.74) | 18.2507 |
| 2000's | 6 (26.09) | 29.6817 |
| 2010's | 12 (52.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Courtois, A; Delugin, L; Fardel, O; Guillouzo, A; Payen, L; Trinquart, Y | 1 |
| Chen, H; Fan, L; Jia, L; Jiang, K; Liu, J; Shao, J; Shen, Z; Zheng, G | 1 |
| Ray, DW; Singh, N; Sommer, P; Taylor, KM; Vosloo, D; Wheeler, R | 1 |
| Check, D; Check, JH; Poretta, T | 1 |
| Allen, MC; Bucca, G; Falcinelli, M; Flaherty, RL; Flint, MS; Hesketh, A; Intabli, H; Patel, BA; Smith, CP | 1 |
| Choi, YH; Jang, JH; Kim, SH; Kwon, TK; Lee, TJ; Min, KJ; Park, EJ; Um, HJ; Woo, SM | 1 |
| Mjoli, PB; Poolman, T; Ray, DW; Singh, N; Sommer, P; Taylor, K | 1 |
| Chen, J; Dong, H; Jia, L; Liu, J; Lu, Y; Shao, J; Wang, J; Xiao, Y; Xie, J; Yu, S; Zheng, N; Zhu, Y | 1 |
| Check, D; Check, JH; Lofberg, P; Wilson, C | 1 |
| Berry, A; D'Acquisto, F; Ianaro, A; Matthews, L; Ray, D; Tersigni, M | 1 |
| Check, JH; Dix, E; Sansoucie, L | 1 |
| Check, JH; Chern, J; Dix, E; Sansoucie, L | 1 |
| Dioufa, N; Kassi, E; Kiaris, H; Papavassiliou, AG | 1 |
| Alavi, M; Bagryanova, L; Chen, HW; Chia, D; Garon, E; Goodglick, L; Horvath, S; Mah, V; Maresh, EL; Marquez-Garban, DC; Pietras, RJ | 1 |
| de Bruin, C; de Herder, WW; Feelders, RA; Hofland, LJ; Lamberts, SW; Nieman, LK; Sprij-Mooij, DM; van Essen, M; van Koetsveld, PM; Waaijers, AM | 1 |
| Debatin, KM; Herr, I; Herzer, K; Krammer, PH; Okouoyo, S; Ridder, R; Ucur, E; von Knebel Doeberitz, M | 1 |
| Colombo, L; Lanari, C; Meiss, R; Molinolo, AA; Soldati, R; Vanzulli, SI | 1 |
| Bilgin, YM; De Herder, WW; Fischer, HR; van der Wiel, HE | 1 |
| Dong, A; Hu, J; Liu, X; Xu, H; Zhao, L | 1 |
| de Coupade, C; Flower, RJ; Parente, L; Russo-Marie, F; Solito, E | 1 |
| Barnes, PJ; Bergmann, M; Kuitert, LM; Newton, R; Seybold, J | 1 |
| Kikuchi, K; Nishigaki, Y; Ohsaki, Y; Toyoshima, E; Yamaguchi, S | 1 |
| Croxtall, JD; Flower, RJ | 1 |
23 other study(ies) available for mifepristone and Lung Neoplasms
| Article | Year |
|---|---|
Reversal of MRP-mediated multidrug resistance in human lung cancer cells by the antiprogestatin drug RU486.
Topics: ATP-Binding Cassette Transporters; Dexamethasone; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Estradiol; Fluoresceins; Hormone Antagonists; Humans; Lung Neoplasms; Mifepristone; Multidrug Resistance-Associated Proteins; Progesterone; Tumor Cells, Cultured | 1999 |
Metapristone suppresses non-small cell lung cancer proliferation and metastasis via modulating RAS/RAF/MEK/MAPK signaling pathway.
Topics: A549 Cells; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Humans; Lung Neoplasms; MAP Kinase Signaling System; Mifepristone; Mitogen-Activated Protein Kinases; Neoplasm Metastasis; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins p21(ras); raf Kinases; Signal Transduction | 2017 |
The tobacco carcinogen NNK drives accumulation of DNMT1 at the GR promoter thereby reducing GR expression in untransformed lung fibroblasts.
Topics: Carcinogenesis; Carcinogens; Cell Line; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Fibroblasts; Gene Expression Regulation, Neoplastic; Humans; Lung; Lung Neoplasms; Mifepristone; Nitrosamines; Promoter Regions, Genetic; Protein Binding; Receptors, Glucocorticoid; Small Cell Lung Carcinoma; Tobacco Smoking | 2018 |
Mifepristone Extends Both Length and Quality of Life in a Patient With Advanced Non-small Cell Lung Cancer that Has Progressed Despite Chemotherapy and a Check-point Inhibitor.
Topics: Adenocarcinoma of Lung; Aged; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; B7-H1 Antigen; Carcinoma, Non-Small-Cell Lung; Disease Progression; Female; Humans; Lung Neoplasms; Mifepristone; Neoplasm Staging; Nivolumab; Quality of Life; Time Factors; Treatment Outcome | 2019 |
Stress hormone-mediated acceleration of breast cancer metastasis is halted by inhibition of nitric oxide synthase.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; DNA Damage; Drug Interactions; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Hydrocortisone; Lung Neoplasms; Mammary Neoplasms, Experimental; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mifepristone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Reactive Nitrogen Species; Reactive Oxygen Species; Stress, Psychological | 2019 |
RU486, a glucocorticoid receptor antagonist, induces apoptosis in U937 human lymphoma cells through reduction in mitochondrial membrane potential and activation of p38 MAPK.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Colorectal Neoplasms; Cytochromes c; Enzyme Activation; Female; HCT116 Cells; Hormone Antagonists; Humans; Leukemia; Lung Neoplasms; Lymphoma; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mifepristone; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Receptors, Glucocorticoid; U937 Cells | 2013 |
The N-terminal transactivation domain of the glucocorticoid receptor mediates apoptosis of human small cell lung cancer cells.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Humans; Lung Neoplasms; Mifepristone; Promoter Regions, Genetic; Protein Structure, Tertiary; Receptors, Glucocorticoid; Small Cell Lung Carcinoma; Transcriptional Activation | 2014 |
In vitro and in vivo efficacy and safety evaluation of metapristone and mifepristone as cancer metastatic chemopreventive agents.
Topics: Animals; Anticarcinogenic Agents; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chemoprevention; Disease Models, Animal; Female; Integrin alpha4; Liver; Lung Neoplasms; Melanoma, Experimental; Mice, Inbred C57BL; Mifepristone; Treatment Outcome | 2016 |
Long-term High-quality Survival with Single-agent Mifepristone Treatment Despite Advanced Cancer.
Topics: Aged; Aged, 80 and over; Carcinoma, Renal Cell; Female; Hormone Antagonists; Humans; Kidney Neoplasms; Lung Neoplasms; Male; Middle Aged; Mifepristone; Neoplasms; Survival Rate | 2016 |
Thiazolidinediones are partial agonists for the glucocorticoid receptor.
Topics: Cell Division; Cell Line, Tumor; Dexamethasone; Enzyme Activation; Genes, Reporter; HeLa Cells; Hormone Antagonists; Humans; Luciferases; Lung Neoplasms; Mifepristone; PPAR gamma; Receptors, Glucocorticoid; Rosiglitazone; Thiazolidinediones; Transfection | 2009 |
Support for the hypothesis that successful immunotherapy of various cancers can be achieved by inhibiting a progesterone associated immunomodulatory protein.
Topics: Animals; Disease Models, Animal; Humans; Immunologic Factors; Immunotherapy; Lung Neoplasms; Mice; Mifepristone; Neoplasms; Pregnancy Proteins; Progesterone; Receptors, Progesterone; RNA, Messenger; Suppressor Factors, Immunologic | 2009 |
Mifepristone treatment improves length and quality of survival of mice with spontaneous lung cancer.
Topics: Animals; Female; Hormone Antagonists; Lung Neoplasms; Male; Mice; Mice, Inbred A; Mifepristone; Quality of Life; Survival Rate | 2010 |
Atypical induction of the unfolded protein response by mifepristone.
Topics: Activating Transcription Factor 4; Activating Transcription Factor 6; Apoptosis; Cell Line, Tumor; eIF-2 Kinase; Eukaryotic Initiation Factor-2; Gene Expression Regulation, Neoplastic; Hormone Antagonists; Humans; Lung Neoplasms; Membrane Glycoproteins; Mifepristone; Receptors, Progesterone; Reverse Transcriptase Polymerase Chain Reaction; Tunicamycin; Unfolded Protein Response | 2010 |
Progesterone and estrogen receptor expression and activity in human non-small cell lung cancer.
Topics: AC133 Antigen; Aldehyde Dehydrogenase; Animals; Antigens, CD; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Culture Media, Conditioned; Endothelial Cells; Endothelium, Vascular; Estradiol; Estrogens; Female; Glycoproteins; Humans; Lung Neoplasms; Male; Mice; Mice, SCID; Mifepristone; Neoplasm Transplantation; Neoplastic Stem Cells; Peptides; Progestins; Receptors, Estrogen; Receptors, Progesterone; Transcription, Genetic; Umbilical Cord; Vascular Endothelial Growth Factor A | 2011 |
Mifepristone effects on tumor somatostatin receptor expression in two patients with Cushing's syndrome due to ectopic adrenocorticotropin secretion.
Topics: ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Adult; Carcinoid Tumor; Cushing Syndrome; Female; Gene Expression Regulation, Neoplastic; Hormone Antagonists; Humans; Lung Neoplasms; Male; Middle Aged; Mifepristone; Receptors, Somatostatin | 2012 |
Glucocorticoid cotreatment induces apoptosis resistance toward cancer therapy in carcinomas.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Arabidopsis Proteins; BH3 Interacting Domain Death Agonist Protein; Carcinoma, Squamous Cell; Carrier Proteins; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspase 8; Caspase 9; Caspases; Cisplatin; Dexamethasone; Drug Resistance, Neoplasm; Fas Ligand Protein; fas Receptor; Fatty Acid Desaturases; Female; Gamma Rays; Gene Expression Regulation, Neoplastic; Genes, bcl-2; HeLa Cells; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Membrane Glycoproteins; Mice; Mice, Nude; Mifepristone; Mitochondria; Neoplasm Proteins; Proto-Oncogene Proteins c-bcl-2; Receptors, Tumor Necrosis Factor; Recombinant Proteins; RNA, Messenger; RNA, Neoplasm; TNF-Related Apoptosis-Inducing Ligand; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Xenograft Model Antitumor Assays | 2003 |
Estrogen or antiprogestin treatment induces complete regression of pulmonary and axillary metastases in an experimental model of breast cancer progression.
Topics: Animals; Apoptosis; Cell Cycle Proteins; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Estradiol; Estrogens; Female; Lung Neoplasms; Lymphatic Metastasis; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mifepristone; Mitosis; Progestins; Receptors, Estrogen; Receptors, Progesterone; Transplantation, Heterologous; Tumor Suppressor Proteins | 2005 |
Treatment of severe psychosis due to ectopic Cushing's syndrome.
Topics: Adrenocorticotropic Hormone; Cushing Syndrome; Drug Therapy, Combination; Etomidate; Female; Hormone Antagonists; Humans; Hydrocortisone; Hypnotics and Sedatives; Lung Neoplasms; Middle Aged; Mifepristone; Psychotic Disorders | 2007 |
Regulation and pharmacokinetics of inducible recombinant TRAIL expression.
Topics: Adenocarcinoma; Adenoviridae; Amino Acid Sequence; Animals; Apoptosis; Base Sequence; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; Genes, Synthetic; Genetic Vectors; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Mifepristone; Molecular Sequence Data; Promoter Regions, Genetic; Protein Structure, Tertiary; Recombinant Fusion Proteins; TNF-Related Apoptosis-Inducing Ligand; Xenograft Model Antitumor Assays | 2007 |
Human annexin 1 is highly expressed during the differentiation of the epithelial cell line A 549: involvement of nuclear factor interleukin 6 in phorbol ester induction of annexin 1.
Topics: Adenocarcinoma; Annexin A1; CCAAT-Enhancer-Binding Proteins; Cell Differentiation; Dexamethasone; Dipeptidyl Peptidase 4; DNA-Binding Proteins; Epithelial Cells; Glucocorticoids; Hormone Antagonists; Humans; Lung Neoplasms; Mifepristone; Nuclear Proteins; Promoter Regions, Genetic; Recombinant Fusion Proteins; Sequence Deletion; Tetradecanoylphorbol Acetate; Transcription Factors; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 1998 |
Repression of cyclooxygenase-2 and prostaglandin E2 release by dexamethasone occurs by transcriptional and post-transcriptional mechanisms involving loss of polyadenylated mRNA.
Topics: Cycloheximide; Cyclooxygenase 2; Dactinomycin; Dexamethasone; Dinoprostone; Enzyme Induction; Hormone Antagonists; Humans; Interleukin-1; Isoenzymes; Kinetics; Lung; Lung Neoplasms; Membrane Proteins; Mifepristone; Prostaglandin-Endoperoxide Synthases; Repetitive Sequences, Nucleic Acid; RNA Processing, Post-Transcriptional; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1998 |
Inhibition of human small cell lung cancer cell growth by methylprednisolone.
Topics: Binding, Competitive; Carcinoma, Small Cell; Cell Division; Cell Survival; Dexamethasone; DNA Fragmentation; Glucocorticoids; Humans; Lung Neoplasms; Methylprednisolone; Mifepristone; Receptors, Glucocorticoid; Reverse Transcriptase Polymerase Chain Reaction; Tritium; Tumor Cells, Cultured | 1999 |
Lipocortin 1 mediates dexamethasone-induced growth arrest of the A549 lung adenocarcinoma cell line.
Topics: Adenocarcinoma; Aldosterone; Annexins; Antibodies, Monoclonal; Calcium-Binding Proteins; Cell Division; Cell Membrane; Dexamethasone; Dinoprostone; Dose-Response Relationship, Drug; Humans; Hydrocortisone; Indomethacin; Kinetics; Lung Neoplasms; Mifepristone; Naproxen; Phospholipases; Progesterone; Recombinant Proteins | 1992 |