Page last updated: 2024-08-23

mifepristone and Labor, Premature

mifepristone has been researched along with Labor, Premature in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.55)18.7374
1990's3 (13.64)18.2507
2000's9 (40.91)29.6817
2010's7 (31.82)24.3611
2020's2 (9.09)2.80

Authors

AuthorsStudies
Bao, J; Garfield, RE; Huang, Q; Li, P; Liu, H; Ye, A1
Boatwright, N; Crockett, SL; De, D; Hansen, CJ; Herington, JL; Newton, J; Paria, BC; Reese, J; Rogers, JH; Simpson, CL; Siricilla, S; Sulikowski, GA; Waterson, AG1
Akins, ML; Auchus, RJ; Ehinger, N; House, M; Mahendroo, M; McIntire, D; Milne, GL; Paria, BC; Reese, J; Socrate, S; Timmons, BC1
Arenas-Hernandez, M; Gomez-Lopez, N; Hajar, O; Mitchell, BF; Olson, DM; Taggart, MJ; Tanaka, S; Tong, WC1
Dorogin, A; Lye, SJ; Shynlova, O; Tsui, P1
Balducci, J; Garfield, RE; Kuon, RJ; Maul, H; Shi, L; Shi, SQ; Sohn, C1
Brown, A; Cornwell, T; Skarra, DV; Solodushko, V; Taylor, MS1
Condon, JC; Gerard, RD; Mendelson, CR; Renthal, NE; Williams, KC1
Dorogin, A; Li, Y; Lye, SJ; Nedd-Roderique, T; Shynlova, O1
Dorogin, A; Li, Y; Lye, SJ; Nedd-Roderique, T; Nguyen, T; Shynlova, O1
Garfield, RE; Marx, SG; Maul, H; Saade, GR; Shi, L1
Langille, BL; Lye, SJ; Mitchell, JA; Shynlova, O; Tsampalieros, A1
Bukowski, R; Doret, M; Garfield, RE; Longo, M; Maner, WL; Maul, H; Saade, GR1
Adamson, SL; Challis, JR; Lye, SJ; Rac, VE; Rurak, D; Scott, CA; Small, C1
Chollet, A; Cirillo, R; Missotten, M; Page, P; Quattropani, A; Scheer, A; Schwarz, MK; Tos, EG1
Dorogin, A; Langille, BL; Lye, SJ; Shynlova, O; Tsui, P1
Al-Hendy, A; Fouad, H; Garfield, RE; Harirah, HM; Salama, SA; Shi, L; Shi, SQ; Wentz, MJ1
Falkay, G; Gálik, M; Gáspár, R; Kolarovszki-Sipiczki, Z1
Deis, RP; Stocco, CO; Tellería, CM1
Branch, DW; Dudley, DJ; Edwin, SS; Mitchell, MD1
Ikuta, Y; Matsuura, K; Okamura, H; Oyamada, I; Usuku, G1
Baulieu, EE; Garfield, RE; Gasc, JM1

Trials

1 trial(s) available for mifepristone and Labor, Premature

ArticleYear
Arrest of preterm labor in rat and mouse by an oral and selective nonprostanoid antagonist of the prostaglandin F2alpha receptor (FP).
    American journal of obstetrics and gynecology, 2007, Volume: 197, Issue:1

    Topics: Animals; Biphenyl Compounds; Drug Therapy, Combination; Female; Humans; Mice; Mifepristone; Obstetric Labor, Premature; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin; Ritodrine; Sulfonamides; Tocolytic Agents; Treatment Outcome; Uterine Contraction

2007

Other Studies

21 other study(ies) available for mifepristone and Labor, Premature

ArticleYear
Nicotine ameliorates inflammatory mediators in RU486 induced preterm labor model through activating cholinergic anti-inflammatory pathway.
    Cytokine, 2022, Volume: 160

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents; Cytokines; Female; Inflammation; Inflammation Mediators; Interleukin-10; Interleukin-4; Interleukin-6; Mifepristone; Neuroimmunomodulation; Nicotine; Obstetric Labor, Premature; Pregnancy; Premature Birth; Rats; Tumor Necrosis Factor-alpha

2022
Arrest of mouse preterm labor until term delivery by combination therapy with atosiban and mundulone, a natural product with tocolytic efficacy.
    Pharmacological research, 2023, Volume: 195

    Topics: Animals; Biological Products; Female; Humans; Infant, Newborn; Mice; Mifepristone; Nifedipine; Obstetric Labor, Premature; Premature Birth; Tocolytic Agents

2023
Prostaglandins are essential for cervical ripening in LPS-mediated preterm birth but not term or antiprogestin-driven preterm ripening.
    Endocrinology, 2014, Volume: 155, Issue:1

    Topics: Animals; Cervical Ripening; Cervix Uteri; Female; Flow Cytometry; Gene Expression Regulation; Lipopolysaccharides; Mice; Mifepristone; Misoprostol; Obstetric Labor, Premature; Pregnancy; Pregnancy, Animal; Premature Birth; Progestins; Prostaglandins; Pyrazoles; Steroids; Sulfonamides; Term Birth

2014
Chemotactic activity of gestational tissues through late pregnancy, term labor, and RU486-induced preterm labor in Guinea pigs.
    American journal of reproductive immunology (New York, N.Y. : 1989), 2015, Volume: 73, Issue:4

    Topics: Amniotic Fluid; Animals; Decidua; Extraembryonic Membranes; Female; Fetal Membranes, Premature Rupture; Gestational Age; Guinea Pigs; Leukocytes; Mifepristone; Myometrium; Obstetric Labor, Premature; Placenta; Pregnancy; Pregnancy Trimester, Third; Progesterone; Term Birth

2015
Monocyte chemoattractant protein-1 (CCL-2) integrates mechanical and endocrine signals that mediate term and preterm labor.
    Journal of immunology (Baltimore, Md. : 1950), 2008, Jul-15, Volume: 181, Issue:2

    Topics: Animals; Chemokine CCL2; Female; Gravidity; Hormone Antagonists; Labor, Obstetric; Macrophages; Mifepristone; Myometrium; Obstetric Labor, Premature; Pregnancy; Progesterone; Rats; Rats, Wistar; Signal Transduction; Up-Regulation

2008
A novel optical method to assess cervical changes during pregnancy and use to evaluate the effects of progestins on term and preterm labor.
    American journal of obstetrics and gynecology, 2011, Volume: 205, Issue:1

    Topics: 17-alpha-Hydroxyprogesterone; Animals; Cervix Uteri; Female; Labor, Obstetric; Mifepristone; Obstetric Labor, Premature; Photography; Pregnancy; Pregnancy Outcome; Progesterone; Progestins; Rats; Rats, Sprague-Dawley

2011
CyPPA, a positive modulator of small-conductance Ca(2+)-activated K(+) channels, inhibits phasic uterine contractions and delays preterm birth in mice.
    American journal of physiology. Cell physiology, 2011, Volume: 301, Issue:5

    Topics: Abortifacient Agents; Animals; Apamin; Calcium; Dinoprost; Female; Mice; Mice, Inbred C57BL; Mifepristone; Myometrium; Obstetric Labor, Premature; Oxytocin; Potassium Channels, Calcium-Activated; Pregnancy; Premature Birth; Pyrazoles; Pyrimidines; Uterine Contraction

2011
MicroRNA-200a serves a key role in the decline of progesterone receptor function leading to term and preterm labor.
    Proceedings of the National Academy of Sciences of the United States of America, 2012, May-08, Volume: 109, Issue:19

    Topics: 20-alpha-Hydroxysteroid Dehydrogenase; Animals; Cells, Cultured; Female; Gene Expression; Hormone Antagonists; Humans; Immunoblotting; Labor, Obstetric; Male; Mice; Mice, Inbred ICR; MicroRNAs; Mifepristone; Myometrium; Obstetric Labor, Premature; Ovariectomy; Pregnancy; Progesterone; Receptors, Progesterone; Reverse Transcriptase Polymerase Chain Reaction; STAT5 Transcription Factor; Uterus

2012
Myometrial immune cells contribute to term parturition, preterm labour and post-partum involution in mice.
    Journal of cellular and molecular medicine, 2013, Volume: 17, Issue:1

    Topics: Animals; Cell Differentiation; Cell Movement; Female; Gene Expression; Humans; Lipopolysaccharides; Macrophages; Mice; Mifepristone; Monocytes; Myometrium; Neutrophils; Obstetric Labor, Premature; Postpartum Period; Pregnancy; Term Birth

2013
Infiltration of myeloid cells into decidua is a critical early event in the labour cascade and post-partum uterine remodelling.
    Journal of cellular and molecular medicine, 2013, Volume: 17, Issue:2

    Topics: Animals; Cell Differentiation; Chemokines; Cytokines; Decidua; Female; Flow Cytometry; Hormone Antagonists; Immunoenzyme Techniques; Leukocytes; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred ICR; Mifepristone; Myeloid Cells; Obstetric Labor, Premature; Postpartum Period; Pregnancy; Pregnancy, Animal; Progesterone; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Uterus

2013
Platelet-activating factor antagonist WEB-2170 inhibits lipopolysaccharide-induced, but not antiprogestin-induced, preterm cervical ripening in timed-pregnant rats.
    American journal of obstetrics and gynecology, 2003, Volume: 189, Issue:4

    Topics: Animals; Azepines; Cervical Ripening; Female; Hormone Antagonists; Lipopolysaccharides; Mifepristone; Obstetric Labor, Premature; Platelet Aggregation Inhibitors; Pregnancy; Progestins; Rats; Rats, Sprague-Dawley; Triazoles

2003
Progesterone and gravidity differentially regulate expression of extracellular matrix components in the pregnant rat myometrium.
    Biology of reproduction, 2004, Volume: 70, Issue:4

    Topics: Animals; Extracellular Matrix Proteins; Female; Gene Expression Regulation; Gravidity; Hormone Antagonists; Labor, Obstetric; Mifepristone; Myometrium; Obstetric Labor, Premature; Parturition; Pregnancy; Pregnancy, Animal; Progesterone; Rats; Rats, Wistar; Receptors, Progesterone

2004
Uterine electromyography characteristics for early diagnosis of mifepristone-induced preterm labor.
    Obstetrics and gynecology, 2005, Volume: 105, Issue:4

    Topics: Abortifacient Agents, Steroidal; Animals; Electromyography; Female; Mifepristone; Obstetric Labor, Premature; Pregnancy; Prenatal Diagnosis; Rats; Rats, Sprague-Dawley; Uterine Contraction

2005
Meloxicam effectively inhibits preterm labor uterine contractions in a chronically catheterized pregnant sheep model: impact on fetal blood flow and fetal-maternal physiologic parameters.
    American journal of obstetrics and gynecology, 2006, Volume: 195, Issue:2

    Topics: Abortifacient Agents, Steroidal; Animals; Anti-Inflammatory Agents, Non-Steroidal; Electromyography; Female; Fetus; Intestines; Kidney; Labor, Induced; Meloxicam; Mifepristone; Models, Animal; Obstetric Labor, Premature; Osmolar Concentration; Pregnancy; Random Allocation; Regional Blood Flow; Sheep; Thiazines; Thiazoles; Tocolytic Agents; Urine; Uterine Contraction

2006
The expression of transforming growth factor beta in pregnant rat myometrium is hormone and stretch dependent.
    Reproduction (Cambridge, England), 2007, Volume: 134, Issue:3

    Topics: Animals; Blotting, Western; Female; Gene Expression; Gravidity; Immunohistochemistry; Labor, Obstetric; Medroxyprogesterone Acetate; Mifepristone; Myometrium; Obstetric Labor, Premature; Pregnancy; Pregnancy, Animal; Random Allocation; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Stress, Mechanical; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transforming Growth Factor beta3

2007
Treatment with an inhibitor of catechol-O-methyltransferase activity reduces preterm birth and impedes cervical resistance to stretch in pregnant rats.
    Reproduction (Cambridge, England), 2007, Volume: 134, Issue:6

    Topics: Animals; Benzophenones; Biomarkers; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Cervical Ripening; Cervix Uteri; Estradiol; Estriol; Female; Hydroxyestrones; Immunohistochemistry; In Vitro Techniques; Mifepristone; Models, Animal; Obstetric Labor, Premature; Pregnancy; Rats; Rats, Sprague-Dawley

2007
Gestagen treatment enhances the tocolytic effect of salmeterol in hormone-induced preterm labor in the rat in vivo.
    American journal of obstetrics and gynecology, 2008, Volume: 198, Issue:3

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Dinoprostone; Female; Mifepristone; Obstetric Labor, Premature; Pregnancy; Progestins; Rats; Rats, Sprague-Dawley; Salmeterol Xinafoate; Tocolysis

2008
Luteolytic action of RU486: modulation of luteal 3 beta-hydroxysteroid dehydrogenase and 20 alpha-hydroxysteroid dehydrogenase activities in late pregnant rats.
    The Journal of steroid biochemistry and molecular biology, 1995, Volume: 52, Issue:6

    Topics: 20-alpha-Hydroxysteroid Dehydrogenase; 20-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; Animals; Corpus Luteum; Diclofenac; Female; Luteolysis; Luteolytic Agents; Mifepristone; Obstetric Labor, Premature; Pregnancy; Progesterone; Rats; Rats, Wistar

1995
Induction of preterm birth in mice by RU486.
    Biology of reproduction, 1996, Volume: 55, Issue:5

    Topics: Abortifacient Agents, Steroidal; Animals; Dinoprost; Dinoprostone; Female; Interleukin-6; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mifepristone; Obstetric Labor, Premature; Pregnancy

1996
Effects of RU486 on the interstitial collagenase in the process of cervical ripening in the pregnant rat.
    Endocrinologia japonica, 1991, Volume: 38, Issue:5

    Topics: Animals; Cervix Uteri; Collagenases; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Female; Matrix Metalloproteinase 1; Mifepristone; Obstetric Labor, Premature; Organ Size; Phenanthrolines; Pregnancy; Pregnancy, Animal; Rats; Rats, Wistar; Time Factors

1991
Effects of the antiprogesterone RU 486 on preterm birth in the rat.
    American journal of obstetrics and gynecology, 1987, Volume: 157, Issue:5

    Topics: Animals; Estrenes; Female; Intercellular Junctions; Mifepristone; Myometrium; Obstetric Labor, Premature; Pregnancy; Pregnancy Maintenance; Progesterone; Rats; Rats, Inbred Strains

1987