mifepristone has been researched along with Innate Inflammatory Response in 64 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (10.94) | 18.7374 |
| 1990's | 7 (10.94) | 18.2507 |
| 2000's | 20 (31.25) | 29.6817 |
| 2010's | 23 (35.94) | 24.3611 |
| 2020's | 7 (10.94) | 2.80 |
| Authors | Studies |
|---|---|
| Edwards, BS; Graves, SW; Saunders, MJ; Sklar, LA; Zhu, J | 1 |
| Alves, BO; de Oliveira, D; de Oliveira, PV; Morgan, LV; Müller, LG; Oltramari, AR; Petry, F; Scapinello, J; Scatolin, M; Volfe, CRB; Zilli, GAL | 1 |
| Bokobza, C; Csaba, Z; Faivre, V; Gressens, P; Guenoun, D; Morin, C; Sautet, I; Schwendimann, L; Van Steenwinckel, J; Young-Ten, P | 1 |
| Bao, J; Garfield, RE; Huang, Q; Li, P; Liu, H; Ye, A | 1 |
| Dehpour, AR; Hasanvand, A; Mokhtari, S; Shams, MH; Sistani Karampour, N | 1 |
| Lin, T; Xu, J; Yang, L | 1 |
| Che, X; Guo, X; He, J; Li, T; Wang, J; Zhang, X | 1 |
| Hu, J; Rong, C; Sun, X; Zhang, J | 1 |
| Choi, R; Fan, Y; Landis, GN; Lee, D; Shen, J; Song, J; Tower, J | 1 |
| Bandyopadhyay, U; Banerjee, C; De, R; Debsharma, S; Mazumder, S; Nag, S; Saha, D; Saha, SJ; Sarkar, S; Siddiqui, AA | 1 |
| Bennett, P; Edey, LF; Georgiou, H; Herbert, BR; Hua, R; Johnson, MR; Lei, K; MacIntyre, D; Markovic, D; Mesiano, S; O'Dea, KP; Takata, M; Waddington, SN | 1 |
| Dye, JA; Henriquez, AR; Kodavanti, UP; Ledbetter, AD; Mauge-Lewis, K; McGee, MA; Miller, CN; Richards, JE; Schladweiler, MC; Snow, SJ | 1 |
| Cai, W; Deng, X; Huang, J; Jiang, T; Li, W; Shen, Z; Sun, X | 1 |
| Abernethie, A; Andrew, R; Hadoke, P; Halligan, D; Keen, J; Livingstone, D; Maltese, G; Morgan, R; O'Callaghan, A; Walker, B | 1 |
| Bethea, JR; Jiang, J; Norden, DM | 1 |
| Annis, JL; Frank, MG; Maier, SF; Watkins, LR | 1 |
| Almeida da Silva, CL; Gaspar-Elsas, MI; Lopes, RS; Luz, RA; Masid-de-Brito, D; Queto, T; Vieira, BM; Xavier-Elsas, P | 1 |
| Dobashi, K; Kikuchi, T; Kita, H; Miyasaka, T; Ohno, I; Okuyama, K; Sora, I; Takayanagi, M; Yamazaki, N | 1 |
| Amat, J; Barrientos, RM; Crysdale, NY; Frank, MG; Hale, MW; Hennessey, PA; Kitt, MM; Lowry, CA; Maier, SF; Spencer, RL; Stamper, CE; Thompson, VM; Watkins, LR | 1 |
| Keenan, CR; Schuliga, MJ; Stewart, AG | 1 |
| Bar-Or, D; Bar-Or, R; Carrick, MM; Mains, CW; Rael, LT; Slone, D; Thomas, GW | 1 |
| Chen, L; Chen, WF; Gao, XQ; Ren, XF; Sun, XC; Xie, JX | 1 |
| Belanoff, JK; Boon, MR; Hunt, H; Meijer, OC; Pereira, AM; Peschier-van der Put, E; Rensen, PC; van Beek, L; van den Heuvel, JK; van Dijk, KW; van Harmelen, V; van Hengel, I | 1 |
| Cheng, MH; Fan, BS; Han, B; Wu, ZT; Yu, JG; Zhang, EH | 1 |
| Bi, Y; Han, L; Hu, Y; Jia, A; Li, C; Li, Y; Liu, G; Liu, H; Lu, Y; Wang, J; Wang, R; Wang, Y; Yang, H; Zhang, Z; Zhao, Y | 1 |
| Beach, ML; Guyre, PM; Lee, HK; Martel, P; Pioli, PA; Rassias, AJ; Wardwell, K; Yeager, MP | 1 |
| Chai, J; Elovitz, MA; Gonzalez, JM; Ofori, E; Xu, H | 1 |
| Hu, G; Liu, R; Shen, Z; Zhang, S; Zhang, X | 1 |
| Costa-Pinto, FA; Lazzarini, R; Palermo-Neto, J; Sakai, M | 1 |
| Avenant, C; Du Toit, A; Hapgood, JP; Verhoog, NJ | 1 |
| Frank, MG; Maier, SF; Thompson, BM; Watkins, LR | 1 |
| Glazer, RI; Kopelovich, L; Lu, J; Upadhyay, G; Yuan, H | 1 |
| Chen, MS; He, YH; Huang, Y; Liu, SM; Luo, JD; Luo, MS; Wu, XQ; Zhang, GS; Zhang, HN | 1 |
| Blais, V; Rivest, S; Zhang, J | 1 |
| Beitz, AJ; Ham, TW; Han, HJ; Kim, HW; Kwon, YB; Lee, JH; Roh, DH; Yang, IS; Yoon, SY | 1 |
| Befus, AD; Ebeling, C; Forsythe, P; Gordon, JR; Vliagoftis, H | 1 |
| Coles, A; Compston, A; Golde, S; Lindquist, JA | 1 |
| Anjos-Valotta, EA; Barja-Fidalgo, C; DeFreitas, MS; Moura, AS; Rodrigues, AL; Sannomyia, P; Silva, SV; Souza, EP | 1 |
| Da Silva, CA; Frossard, N; Kassel, O; Lacroix, EJ; Lebouquin, R | 1 |
| Estell, K; Pastva, A; Schoeb, TR; Schwiebert, LM | 1 |
| Albertini, R; Bjordal, JM; de Carvalho, FA; Iversen, VV; Lopes-Martins, PS; Lopes-Martins, RA; Neto, HC | 1 |
| Corey, DR; Hardy, DB; Janowski, BA; Mendelson, CR | 1 |
| Chen, L; Da, J; Hedenstierna, G | 1 |
| Blaxall, BC; Dhawan, L; Liu, B; Taubman, MB | 1 |
| Berman, BM; Lao, L; Li, A; Ren, K; Tan, M; Wang, Y; Zhang, H; Zhang, RX | 1 |
| Beitz, AJ; Han, HJ; Kim, HW; Kwon, YB; Lee, HJ; Lee, JH; Roh, DH; Uh, DK; Yoon, SY | 1 |
| Duda, E; Eder, K; Lázár, G; Paszt, A; Szabolcs, A; Takács, T; Tiszlavicz, L | 1 |
| Ahluwalia, A; Brain, SD; Flower, RJ; Newbold, P | 1 |
| Chrousos, GP; Crofford, L; Karalis, K; Wilder, RL | 1 |
| Farsky, SP; Garcia-Leme, J; Sannomiya, P | 1 |
| Kubes, P; Rioux, K; Swain, MG; Tjandra, K | 1 |
| Carroll, JL; Pruett, SB; Vinson, RB | 1 |
| Bleiberg-Daniel, F; Delautier, D; Feldmann, G; Lardeux, B; Lestriez, V; Saadane, A | 1 |
| Calder, AA; Critchley, HO; Denison, FC; Elliott, CL; Kelly, RW; Riley, SC | 1 |
| Adcock, IM; Barnes, PJ; Cosio, B; Ito, K; Jazrawi, E | 1 |
| Marucha, PT; Mercado, AM; Padgett, DA; Sheridan, JF | 1 |
| Costello, A; Hargreaves, KM | 1 |
| Bürger, W; Göhler, K; Hirschelmann, R; Schade, R | 1 |
| Bekemeier, H; Hirschelmann, R; Klingner, E; Schade, R | 1 |
| Hodgen, GD; Sinosich, MJ; Williams, RF; Wolf, JP | 1 |
| Barnes, K; Brandon, DD; Brightwell, D; Chrousos, GP; Kawai, S; Knazek, RA; Laue, L; Loriaux, DL | 1 |
| Chrousos, GP; Laue, L; Loriaux, DL | 1 |
| Flower, RJ; Moon, D; Peers, SH | 1 |
| Bekemeier, H; Hirschelmann, R; Klingner, E; Schmidt, K | 1 |
1 trial(s) available for mifepristone and Innate Inflammatory Response
| Article | Year |
|---|---|
The effect of mifepristone administration on leukocyte populations, matrix metalloproteinases and inflammatory mediators in the first trimester cervix.
Topics: Abortifacient Agents, Steroidal; Abortion, Induced; Adult; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Biomarkers; Cervix Uteri; Chemokines; Female; Humans; Inflammation; Leukocyte Common Antigens; Leukocyte Elastase; Leukocytes; Matrix Metalloproteinases; Mifepristone; Pregnancy; Pregnancy Trimester, First; Prostaglandins; Tissue Inhibitor of Metalloproteinases | 2000 |
63 other study(ies) available for mifepristone and Innate Inflammatory Response
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Inflammation; Kinetics; Microspheres; Peptide Hydrolases; Peptides; Reproducibility of Results; Temperature | 2010 |
Investigation of the anti-inflammatory effects of stigmasterol in mice: insight into its mechanism of action.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Inflammation; Male; Mice; Mifepristone; Molecular Docking Simulation; Pain; Peritonitis; Receptors, Glucocorticoid; Stigmasterol | 2021 |
The Impact of Mouse Preterm Birth Induction by RU-486 on Microglial Activation and Subsequent Hypomyelination.
Topics: Animals; Animals, Newborn; Female; Humans; Inflammation; Lipopolysaccharides; Mice; Microglia; Mifepristone; Pregnancy; Premature Birth | 2022 |
Nicotine ameliorates inflammatory mediators in RU486 induced preterm labor model through activating cholinergic anti-inflammatory pathway.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents; Cytokines; Female; Inflammation; Inflammation Mediators; Interleukin-10; Interleukin-4; Interleukin-6; Mifepristone; Neuroimmunomodulation; Nicotine; Obstetric Labor, Premature; Pregnancy; Premature Birth; Rats; Tumor Necrosis Factor-alpha | 2022 |
Protective assessment of progesterone and its receptor on experimental diabetic neuropathy: Antioxidant and anti-inflammatory effects.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Inflammation; Male; Mifepristone; Oxidative Stress; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, Progesterone; Sciatic Nerve | 2023 |
β-sitosterol targets glucocorticoid receptor to reduce airway inflammation and remodeling in allergic asthma.
Topics: Airway Remodeling; Animals; Asthma; Collagen; Disease Models, Animal; Humans; Inflammation; Lung; Mice; Mice, Inbred BALB C; Mifepristone; Molecular Docking Simulation; Ovalbumin; Receptors, Glucocorticoid; Sitosterols; Transforming Growth Factor beta1 | 2023 |
The new application of mifepristone in the relief of adenomyosis-caused dysmenorrhea.
Topics: Adenomyosis; Cell Line; Cell Movement; Cells, Cultured; Dysmenorrhea; Enzyme-Linked Immunosorbent Assay; Female; Humans; Inflammation; Interleukin-6; Mast Cells; Mifepristone; Stromal Cells; Tumor Necrosis Factor-alpha | 2020 |
Mifepristone inhibits inflammation pulmonary fibrosis rats through NF-κB signaling pathway.
Topics: Animals; Inflammation; Mifepristone; NF-kappa B; Pulmonary Fibrosis; Rats; Signal Transduction | 2022 |
Mifepristone/RU486 acts in Drosophila melanogaster females to counteract the life span-shortening and pro-inflammatory effects of male Sex Peptide.
Topics: Animals; Animals, Genetically Modified; Drosophila Proteins; Female; Green Fluorescent Proteins; Inflammation; Intercellular Signaling Peptides and Proteins; Longevity; Male; Mifepristone; Peptides | 2017 |
Acute mental stress induces mitochondrial bioenergetic crisis and hyper-fission along with aberrant mitophagy in the gut mucosa in rodent model of stress-related mucosal disease.
Topics: Adenosine Triphosphate; Animals; Antipsychotic Agents; bcl-2-Associated X Protein; Cold Temperature; Corticosterone; Electron Transport Complex I; Gastric Mucosa; Gene Expression Regulation; Immobilization; Inflammation; Membrane Transport Proteins; Mifepristone; Mitochondria; Mitochondrial Dynamics; Mitochondrial Precursor Protein Import Complex Proteins; Mitochondrial Proteins; Mitophagy; NF-kappa B; Organophosphorus Compounds; Oxidative Stress; Piperidines; Protein Kinases; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Glucocorticoid; Stomach; Stress, Psychological; Superoxides; Ubiquitin-Protein Ligases | 2017 |
Progesterone, the maternal immune system and the onset of parturition in the mouse.
Topics: Animals; Chemokines; Connexin 43; Cyclooxygenase 2; Cytokines; Female; Inflammation; Mice; Mifepristone; Monocytes; Myometrium; Neutrophils; Parturition; Progesterone | 2018 |
Adrenergic and glucocorticoid receptor antagonists reduce ozone-induced lung injury and inflammation.
Topics: Adrenergic beta-Antagonists; Animals; Bronchoalveolar Lavage Fluid; Hormone Antagonists; Inflammation; Inflammation Mediators; Lung Injury; Male; Mifepristone; Ozone; Rats; Rats, Inbred WKY; Receptors, Adrenergic; Receptors, Glucocorticoid | 2018 |
Icariin inhibits LPS-induced cell inflammatory response by promoting GRα nuclear translocation and upregulating GRα expression.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Flavonoids; Gene Expression Regulation; HeLa Cells; Hormone Antagonists; Humans; Inflammation; Interleukin-6; Lipopolysaccharides; Mice; Mifepristone; RAW 264.7 Cells; Receptors, Glucocorticoid; RNA Interference; Translocation, Genetic; Tumor Necrosis Factor-alpha; Up-Regulation | 2018 |
Species-specific regulation of angiogenesis by glucocorticoids reveals contrasting effects on inflammatory and angiogenic pathways.
Topics: Angiogenesis Inhibitors; Animals; Blood Vessels; Female; Gene Expression Profiling; High-Throughput Nucleotide Sequencing; Horse Diseases; Horses; Hydrocortisone; Inflammation; Male; Metabolic Networks and Pathways; Mice; Mifepristone; Neovascularization, Pathologic; Real-Time Polymerase Chain Reaction; Species Specificity; Transcriptome | 2018 |
Impaired CD8 T cell antiviral immunity following acute spinal cord injury.
Topics: Acute Disease; Animals; Antiviral Agents; Body Weight; CD8-Positive T-Lymphocytes; Cells, Cultured; Cytokines; Disease Models, Animal; Female; Flow Cytometry; Hemagglutinin Glycoproteins, Influenza Virus; Hormone Antagonists; Inflammation; Lung; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mifepristone; Orthomyxoviridae Infections; Spinal Cord Injuries; Spleen | 2018 |
Glucocorticoids mediate stress induction of the alarmin HMGB1 and reduction of the microglia checkpoint receptor CD200R1 in limbic brain structures.
Topics: Animals; Brain; Corticosterone; Glucocorticoids; Hippocampus; HMGB1 Protein; Inflammation; Limbic System; Lipopolysaccharides; Male; Microglia; Mifepristone; Neuroimmunomodulation; Rats; Rats, Sprague-Dawley; Receptors, Immunologic; Stress, Psychological | 2019 |
Essential roles of endogenous glucocorticoids and TNF/TNFR1 in promoting bone-marrow eosinopoiesis in ovalbumin-sensitized, airway-challenged mice.
Topics: Animals; Bone Marrow; Corticosterone; Eosinophilia; Eosinophils; Female; Glucocorticoids; Inflammation; Metyrapone; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mifepristone; Ovalbumin; Peritoneal Cavity; Receptors, Tumor Necrosis Factor, Type I; Tumor Necrosis Factor-alpha | 2014 |
The involvement of glucocorticoids in psychological stress-induced exacerbations of experimental allergic asthma.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Corticosterone; Disease Models, Animal; Female; Glucocorticoids; Inflammation; Interleukin-12; Interleukin-13; Male; Mice; Mice, Inbred BALB C; Mifepristone; Receptors, Glucocorticoid; Respiratory System; Sex Factors; Stress, Psychological; T-Lymphocytes, Regulatory; Th2 Cells | 2014 |
Greater glucocorticoid receptor activation in hippocampus of aged rats sensitizes microglia.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Aging; Animals; Catalysis; Cells, Cultured; Corticosterone; Hippocampus; Inflammation; Male; Memory; Memory Disorders; Microglia; Mifepristone; Physical Conditioning, Animal; Rats, Inbred F344; Receptors, Glucocorticoid | 2015 |
Pro-inflammatory mediators increase levels of the noncoding RNA GAS5 in airway smooth muscle and epithelial cells.
Topics: Anti-Inflammatory Agents; Cell Line; Cytokines; Dexamethasone; Epithelial Cells; Humans; Inflammation; Lung; Mifepristone; Muscle, Smooth; RNA, Long Noncoding; Up-Regulation | 2015 |
Anti-Inflammatory Activity in the Low Molecular Weight Fraction of Commercial Human Serum Albumin (LMWF5A).
Topics: Dexamethasone; Humans; Inflammation; Leukocytes, Mononuclear; Lipopolysaccharides; Mifepristone; Molecular Weight; Primary Cell Culture; Serum Albumin; Tumor Necrosis Factor-alpha | 2016 |
Glucocorticoid receptor is involved in the neuroprotective effect of ginsenoside Rg1 against inflammation-induced dopaminergic neuronal degeneration in substantia nigra.
Topics: Animals; Apomorphine; Dopamine; Female; Ginsenosides; Inflammation; Lipopolysaccharides; Microglia; Mifepristone; Neurons; Neuroprotective Agents; Nitric Oxide; Rats, Wistar; Receptors, Glucocorticoid; Substantia Nigra; Tumor Necrosis Factor-alpha | 2016 |
Identification of a selective glucocorticoid receptor modulator that prevents both diet-induced obesity and inflammation.
Topics: Animals; Body Weight; Diet, High-Fat; Inflammation; Male; Mice; Mice, Inbred C57BL; Mifepristone; Obesity; RAW 264.7 Cells; Receptors, Glucocorticoid | 2016 |
Diurnal Variation of the Peripheral Cholinergic Antiinflammatory Function in Mice.
Topics: Acetylcholine; Aconitine; Animals; Circadian Rhythm; Corticosterone; Cytokines; Disease Models, Animal; Hormone Antagonists; Inflammation; Kidney; Lipopolysaccharides; Liver; Mice; Mice, Inbred C57BL; Mifepristone; Nicotinic Antagonists; Vesicular Acetylcholine Transport Proteins | 2016 |
Glucocorticoid receptor promotes the function of myeloid-derived suppressor cells by suppressing HIF1α-dependent glycolysis.
Topics: Animals; Dexamethasone; Disease Models, Animal; Down-Regulation; Glycolysis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immune Tolerance; Immunity, Innate; Inflammation; Lipopolysaccharides; Liver; Mice, Inbred C57BL; Mifepristone; Myeloid-Derived Suppressor Cells; Receptors, Glucocorticoid; Signal Transduction | 2018 |
In vivo exposure to high or low cortisol has biphasic effects on inflammatory response pathways of human monocytes.
Topics: Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Anti-Inflammatory Agents; Etomidate; Female; Glucocorticoids; Humans; Hydrocortisone; Inflammation; Infusions, Intravenous; Male; Middle Aged; Mifepristone; Monocytes; Receptors, Glucocorticoid | 2008 |
Preterm and term cervical ripening in CD1 Mice (Mus musculus): similar or divergent molecular mechanisms?
Topics: Analysis of Variance; Animals; Cervical Ripening; Cervix Uteri; Cytokines; Databases, Genetic; Desmoglein 1; Disease Models, Animal; Female; Gestational Age; Immunohistochemistry; Inflammation; Lipopolysaccharides; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mifepristone; Oligonucleotide Array Sequence Analysis; Pregnancy; Premature Birth; Principal Component Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Tissue Inhibitor of Metalloproteinase-2 | 2009 |
Effects of endogenous glucocorticoids on allergic inflammation and T(H)1 /T(H)2 balance in airway allergic disease.
Topics: Animals; Bone Marrow; Cell Count; Concanavalin A; Corticosterone; Eosinophils; Glucocorticoids; Immunization; Inflammation; Interferon-gamma; Interleukin-4; Interleukin-5; Leukocyte Count; Lung; Lymphocyte Activation; Lymphocytes; Male; Metyrapone; Mice; Mice, Inbred BALB C; Mifepristone; Ovalbumin; Respiratory Hypersensitivity; Sneezing; Specific Pathogen-Free Organisms; Spleen; Th1 Cells; Th2 Cells | 2009 |
Diazepam decreases leukocyte-endothelium interactions in situ.
Topics: Animals; Arginine; Carrageenan; Diazepam; Endothelium, Vascular; Inflammation; Leukocyte Rolling; Leukocytes; Male; Mesentery; Mifepristone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Psychotropic Drugs; Rats; Rats, Wistar | 2010 |
Glucocorticoid-independent repression of tumor necrosis factor (TNF) alpha-stimulated interleukin (IL)-6 expression by the glucocorticoid receptor: a potential mechanism for protection against an excessive inflammatory response.
Topics: Animals; Carrier Proteins; Chlorocebus aethiops; COS Cells; Epithelial Cells; Gene Expression Regulation; Hormone Antagonists; Humans; Inflammation; Interleukin-6; Mifepristone; Nerve Tissue Proteins; Phosphorylation; Promoter Regions, Genetic; Receptors, Glucocorticoid; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2011 |
Glucocorticoids mediate stress-induced priming of microglial pro-inflammatory responses.
Topics: Adrenalectomy; Animals; Glucocorticoids; Hippocampus; Inflammation; Interleukin-1beta; Lipopolysaccharides; Male; Microglia; Mifepristone; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Stress, Psychological | 2012 |
The chemopreventive effect of mifepristone on mammary tumorigenesis is associated with an anti-invasive and anti-inflammatory gene signature.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Hormonal; Carcinogens; Carcinoma; Chemoprevention; Drug Evaluation, Preclinical; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Hormone Antagonists; Inflammation; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Microarray Analysis; Mifepristone; Neoplasm Invasiveness; Paired Box Transcription Factors; PAX8 Transcription Factor | 2012 |
Endogenous glucocorticoids inhibit myocardial inflammation induced by lipopolysaccharide: involvement of regulation of histone deacetylation.
Topics: Animals; Cytokines; Disease Models, Animal; Glucocorticoids; Histone Deacetylases; Hydrocortisone; Hydroxamic Acids; Inflammation; Lipopolysaccharides; Male; Mifepristone; Myocardium; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Signal Transduction | 2012 |
In altering the release of glucocorticoids, ketorolac exacerbates the effects of systemic immune stimuli on expression of proinflammatory genes in the brain.
Topics: Adrenal Glands; Animals; Brain; Chemokine CCL2; Corticosterone; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Feedback; Gene Expression; Glucocorticoids; Hypothalamus; I-kappa B Proteins; Immunity; Inflammation; Interleukin-1; Isoenzymes; Ketorolac; Male; Microcirculation; Mifepristone; NF-KappaB Inhibitor alpha; Pituitary Gland; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; RNA, Messenger; Signal Transduction; Tumor Necrosis Factor-alpha | 2002 |
The anti-inflammatory effect of bee venom stimulation in a mouse air pouch model is mediated by adrenal medullary activity.
Topics: Adrenal Medulla; Adrenalectomy; Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents; Bee Venoms; Catecholamines; Cell Movement; Disease Models, Animal; Exudates and Transudates; Hormone Antagonists; Inflammation; Injections, Subcutaneous; Leukocytes; Male; Mice; Mice, Inbred ICR; Mifepristone; Receptors, Steroid; Tumor Necrosis Factor-alpha; Zymosan | 2003 |
Opposing effects of short- and long-term stress on airway inflammation.
Topics: Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cytokines; Inflammation; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mifepristone; Receptors, Steroid; Stress, Physiological | 2004 |
Decreased iNOS synthesis mediates dexamethasone-induced protection of neurons from inflammatory injury in vitro.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Cerebral Cortex; Coculture Techniques; Dexamethasone; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Hormone Antagonists; Immunohistochemistry; Inflammation; Interferon-gamma; Lipopolysaccharides; Microglia; Mifepristone; Neurons; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2003 |
Impairment of inflammatory response in adult rats submitted to maternal undernutrition during early lactation: role of insulin and glucocorticoid.
Topics: Animals; Blood Glucose; Carrageenan; Cell Movement; Edema; Endothelium; Energy Intake; Feeding Behavior; Female; Fetus; Glucocorticoids; Immunohistochemistry; Inflammation; Insulin; Intercellular Adhesion Molecule-1; Lactation; Leukocytes; Male; Malnutrition; Mifepristone; Neutrophils; Nutrition Disorders; Pleurisy; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar | 2003 |
Paradoxical early glucocorticoid induction of stem cell factor (SCF) expression in inflammatory conditions.
Topics: Budesonide; Cells, Cultured; DNA, Complementary; Down-Regulation; Drug Synergism; Fibroblasts; Glucocorticoids; Humans; Inflammation; Interleukin-1; Lung; Mifepristone; NF-kappa B; Plasmids; Receptors, Glucocorticoid; RNA Stability; RNA, Messenger; Stem Cell Factor; Tissue Engineering; Transcription, Genetic; Transfection | 2004 |
RU486 blocks the anti-inflammatory effects of exercise in a murine model of allergen-induced pulmonary inflammation.
Topics: Aerobiosis; Allergens; Animals; Bronchoalveolar Lavage Fluid; DNA; Electrophoretic Mobility Shift Assay; Female; Hormone Antagonists; Inflammation; Interleukin-8; Mice; Mice, Inbred BALB C; Mifepristone; NF-kappa B; Ovalbumin; Physical Conditioning, Animal; Physical Exertion; Pneumonia; Receptors, Glucocorticoid; Sample Size; Vascular Cell Adhesion Molecule-1 | 2005 |
Steroid receptor antagonist mifepristone inhibits the anti-inflammatory effects of photoradiation.
Topics: Animals; Hormone Antagonists; Hydrocortisone; Inflammation; Light; Male; Mice; Mice, Inbred BALB C; Mifepristone; Pleurisy; Random Allocation | 2006 |
Progesterone receptor plays a major antiinflammatory role in human myometrial cells by antagonism of nuclear factor-kappaB activation of cyclooxygenase 2 expression.
Topics: Cells, Cultured; Cyclooxygenase 2; DNA-Binding Proteins; Female; Gene Expression Regulation, Enzymologic; Humans; I-kappa B Proteins; Inflammation; Interleukin-1beta; Mifepristone; Myometrium; NF-kappa B; NF-KappaB Inhibitor alpha; Promoter Regions, Genetic; Receptors, Progesterone; Regulatory Elements, Transcriptional; RNA, Small Interfering; Tumor Cells, Cultured; Up-Regulation | 2006 |
Nitric oxide up-regulates the glucocorticoid receptor and blunts the inflammatory reaction in porcine endotoxin sepsis.
Topics: Administration, Inhalation; Animals; Anti-Inflammatory Agents; Blood Gas Analysis; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Hormone Antagonists; Hydrocortisone; Immunohistochemistry; Inflammation; Infusions, Intravenous; Lipopolysaccharides; Mifepristone; Nitric Oxide; Prospective Studies; Pulmonary Wedge Pressure; Random Allocation; Receptors, Glucocorticoid; Respiratory Distress Syndrome; Sepsis; Swine; Up-Regulation | 2007 |
A novel role for the glucocorticoid receptor in the regulation of monocyte chemoattractant protein-1 mRNA stability.
Topics: Animals; Anti-Inflammatory Agents; Atherosclerosis; Cell-Free System; Cells, Cultured; Chemokine CCL2; Dexamethasone; Hormone Antagonists; Humans; Inflammation; Male; Mifepristone; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; RNA Stability | 2007 |
Corticosterone mediates electroacupuncture-produced anti-edema in a rat model of inflammation.
Topics: Adrenal Glands; Adrenalectomy; Animals; Corticosterone; Disease Models, Animal; Edema; Electroacupuncture; Freund's Adjuvant; Hormone Antagonists; Hyperalgesia; Inflammation; Male; Mifepristone; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Reference Values | 2007 |
Low-frequency electroacupuncture suppresses carrageenan-induced paw inflammation in mice via sympathetic post-ganglionic neurons, while high-frequency EA suppression is mediated by the sympathoadrenal medullary axis.
Topics: Adrenal Medulla; Adrenalectomy; Adrenergic Agents; Animals; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Radiation; Edema; Electric Stimulation; Electroacupuncture; Ganglia, Sympathetic; Hormone Antagonists; Inflammation; Male; Mice; Mice, Inbred ICR; Mifepristone; Neurons; Pain Threshold; Peroxidase; Time Factors | 2008 |
Effects of glucocorticoid agonist and antagonist on the pathogenesis of L-arginine-induced acute pancreatitis in rat.
Topics: Acute Disease; Amylases; Animals; Arginine; Disease Models, Animal; Glucocorticoids; Inflammation; Interleukin-6; L Cells; Macrophage Migration-Inhibitory Factors; Male; Methylprednisolone; Mice; Mifepristone; Pancreatitis; Rats; Rats, Wistar | 2008 |
Topical glucocorticoids inhibit neurogenic inflammation: involvement of lipocortin 1.
Topics: Administration, Topical; Animals; Annexin A1; Betamethasone; Edema; Glucocorticoids; Inflammation; Male; Mifepristone; Rats; Rats, Wistar | 1995 |
Glucocorticoid and/or glucocorticoid antagonist effects in inflammatory disease-susceptible Lewis rats and inflammatory disease-resistant Fischer rats.
Topics: Adrenal Glands; Animals; Arthritis; Carrageenan; Dexamethasone; Disease Susceptibility; Genetic Predisposition to Disease; Inflammation; Male; Mifepristone; Organ Size; Peptidoglycan; Polysaccharides, Bacterial; Rats; Rats, Inbred F344; Rats, Inbred Lew; Spleen; Streptococcus; Thymus Gland | 1995 |
Secreted glucocorticoids regulate leukocyte-endothelial interactions in inflammation. A direct vital microscopic study.
Topics: Adrenalectomy; Animals; CD18 Antigens; Cell Adhesion; Cycloheximide; Dactinomycin; Endothelium, Vascular; Glucocorticoids; Immunologic Techniques; Inflammation; Male; Metyrapone; Microcirculation; Mifepristone; Rats; Rats, Wistar; Regional Blood Flow | 1995 |
Endogenous glucocorticoids inhibit neutrophil recruitment to inflammatory sites in cholestatic rats.
Topics: Animals; Carrageenan; Cell Movement; Cholestasis; Glucocorticoids; Inflammation; Male; Mifepristone; Neutrophils; Rats; Rats, Sprague-Dawley | 1996 |
Mechanism of suppressed neutrophil mobilization in a mouse model for binge drinking: role of glucocorticoids.
Topics: Alcohol Drinking; Animals; Corticosterone; Disease Models, Animal; Ethanol; Female; Inflammation; Macrophages, Peritoneal; Mice; Mice, Inbred Strains; Mifepristone; Neutrophil Activation; Neutrophils; Peritoneal Cavity; Propionibacterium acnes; Tumor Necrosis Factor-alpha | 1998 |
Down-regulation of liver RNA breakdown by turpentine administration in the starved rat: autophagy and relevant factors.
Topics: Acute Disease; Animals; Down-Regulation; Inflammation; Liver; Male; Mifepristone; Perfusion; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; RNA; Starvation; Turpentine | 1999 |
p65-activated histone acetyltransferase activity is repressed by glucocorticoids: mifepristone fails to recruit HDAC2 to the p65-HAT complex.
Topics: Acetylation; Acetyltransferases; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cell Nucleus; Chromatin; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Glucocorticoids; Granulocyte-Macrophage Colony-Stimulating Factor; Histone Acetyltransferases; Histone Deacetylase 2; Histone Deacetylases; Histones; Hormone Antagonists; Humans; Immunohistochemistry; Inflammation; Interleukin-1; Lysine; Mifepristone; NF-kappa B; Precipitin Tests; Protein Binding; Receptors, Glucocorticoid; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Saccharomyces cerevisiae Proteins; Transcription Factor RelA; Transcription, Genetic; Tumor Cells, Cultured | 2001 |
Altered kinetics of IL-1 alpha, IL-1 beta, and KGF-1 gene expression in early wounds of restrained mice.
Topics: Animals; Female; Fibroblast Growth Factor 7; Fibroblast Growth Factors; Gene Expression Regulation; Glucocorticoids; Inflammation; Interleukin-1; Kinetics; Mice; Mice, Inbred Strains; Mifepristone; Restraint, Physical; Reverse Transcriptase Polymerase Chain Reaction; Stress, Psychological; Time Factors; Wound Healing; Wounds and Injuries | 2002 |
Glucocorticoids suppress levels of immunoreactive bradykinin in inflamed tissue as evaluated by microdialysis probes.
Topics: Animals; Anisomycin; Bradykinin; Carrageenan; Dialysis; Female; Glucocorticoids; Humans; Inflammation; Male; Methylprednisolone; Mifepristone; Pain, Postoperative; Radioimmunoassay; Rats; Rats, Inbred Strains; Time Factors | 1990 |
Modulation of rat C-reactive protein serum level by dexamethasone and adrenaline--comparison with the response of alpha 2-acute phase globulin.
Topics: alpha-Macroglobulins; Animals; Arthritis, Experimental; C-Reactive Protein; Circadian Rhythm; Dexamethasone; Epinephrine; Estrenes; Female; Inflammation; Isoproterenol; Male; Mifepristone; Rats; Rats, Inbred Strains; Turpentine | 1987 |
Dexamethasone antagonism by RU 38486 in inflammatory reactions of the rat. Part 2: Biochemical parameters: RNA content of inflammation cells and acute phase reactants of the blood.
Topics: Acute-Phase Proteins; Animals; Arthritis, Experimental; Dexamethasone; Estrenes; Exudates and Transudates; Glucocorticoids; Inflammation; Iodine Radioisotopes; Mifepristone; Neutrophils; Rats; RNA | 1988 |
RU 486 mediated leukocytic inflammatory reaction at the utero-placental interface.
Topics: Animals; Female; Inflammation; Maternal-Fetal Exchange; Mifepristone; Neutrophils; Placenta; Pregnancy; Pregnancy-Associated Plasma Protein-A; Progesterone; Uterus | 1989 |
Receptor-mediated effects of glucocorticoids on inflammation: enhancement of the inflammatory response with a glucocorticoid antagonist.
Topics: Alprostadil; Animals; Carrageenan; Dexamethasone; Estrenes; Glucocorticoids; Inflammation; Kinetics; Leukocytes; Leukotriene B4; Male; Mifepristone; Rats; Rats, Inbred Strains; Receptors, Glucocorticoid | 1988 |
Glucocorticoid antagonists and the role of glucocorticoids at the resting and stress state.
Topics: Animals; Arousal; Dexamethasone; Estrenes; Glucocorticoids; Humans; Hydrocortisone; Immune Tolerance; Inflammation; Leukocyte Count; Mifepristone; Rats; Rats, Inbred Strains; Receptors, Glucocorticoid; Stress, Psychological | 1988 |
Reversal of the anti-inflammatory effects of dexamethasone by the glucocorticoid antagonist RU 38486.
Topics: Animals; Carrageenan; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Estrenes; Inflammation; Male; Mifepristone; Pleurisy; Rats; Rats, Inbred Strains | 1988 |
Dexamethasone antagonism by RU 38,486 in inflammatory reactions of the rat and mouse. Part 1: Degree of inflammation.
Topics: Animals; Anti-Inflammatory Agents; Dexamethasone; Estrenes; Glucocorticoids; Inflammation; Mice; Mifepristone; Rats; Species Specificity | 1988 |