mifepristone has been researched along with Hormone-Dependent Neoplasms in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (24.00) | 18.7374 |
| 1990's | 13 (52.00) | 18.2507 |
| 2000's | 6 (24.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ecker, GF; Haslinger, E; Hödl, C; Kunert, O; Raunegger, K; Schramm, HW; Seger, C; Steiner, R; Strauss, WS; Strommer, R; Sturm, S | 1 |
| Atkinson, N; Broaddus, R; Burke, T; Iyer, RB; Johnson, AJ; Jung, MS; Ramondetta, LM; Smith, JA; Sun, CC | 1 |
| Augustowska, K; Gregoraszczuk, EL; Krzysiek, J; Milewicz, T; Ryś, J; Sztefko, K | 1 |
| Besch-Williford, C; Brekken, RA; Hyder, SM; Liang, Y | 1 |
| Balk, SP; Barb, D; Bubley, GJ; Gelmann, EP; Kantoff, PW; Manola, J; Mantzoros, C; Oh, WK; Smith, M; Taplin, ME | 1 |
| Heikinheimo, O | 1 |
| Koper, JW; Lamberts, SW | 1 |
| Olson, JJ | 1 |
| Grunberg, SM | 1 |
| Cornish, AL; Lee, CS; Musgrove, EA; Sutherland, RL; Swarbrick, A | 1 |
| Baulieu, EE; Cadepond, F; Ulmann, A | 1 |
| Kimmick, GG; Muss, HB | 1 |
| El Etreby, MF; Liang, Y; Schoenlein, PV; Wrenn, RW | 1 |
| Charreau, E; Lamb, C; Lanari, C; Luthy, IA; Molinolo, AA; Montecchia, MF; Pazos, P; Vanzulli, S | 1 |
| Vastag, B | 1 |
| Beck, CA; Edwards, DP | 1 |
| Distler, W; Vering, A | 1 |
| Katzenellenbogen, BS; Keith, D; Read, LD; Slamon, DJ | 1 |
| Kokai, Y; Lyttle, CR; Modiano, JF; Nowell, PC; Pykett, MJ; Weiner, DB | 1 |
| el Etreby, MF; Michna, H; Nishino, Y; Schneider, MR | 1 |
| Okada, H | 1 |
| Dubois, C; Ulmann, A | 1 |
| Baudot, N; Chomette, G; Fournier, S; Gompel, A; Kuttenn, F; Malet, C; Mauvais-Jarvis, P; Mietze, V; Spritzer, P | 1 |
| d'Arville, CN; Horwitz, KB; Sedlacek, SM; Wei, LL | 1 |
10 review(s) available for mifepristone and Hormone-Dependent Neoplasms
| Article | Year |
|---|---|
[Multiple usages for antiprogestins].
Topics: Abortifacient Agents, Steroidal; Abortion, Therapeutic; Breast Neoplasms; Female; Hormone Antagonists; Humans; Male; Meningeal Neoplasms; Meningioma; Mifepristone; Neoplasms, Hormone-Dependent; Pregnancy; Progestins; Receptors, Progesterone | 1994 |
Laboratory evidence for the hormonal dependency of meningiomas.
Topics: Combined Modality Therapy; Female; Glucocorticoids; Gonadal Steroid Hormones; Humans; Male; Meningeal Neoplasms; Meningioma; Mifepristone; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Receptors, Steroid; Sex Factors; Steroids | 1994 |
Role of antiprogestational therapy for meningiomas.
Topics: Buserelin; Clinical Trials as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Double-Blind Method; Estradiol; Estrogen Antagonists; Female; Glucocorticoids; Gonadal Steroid Hormones; Humans; Male; Meningeal Neoplasms; Meningioma; Menopause; Mifepristone; Neoplasms, Hormone-Dependent; Pituitary-Adrenal System; Progesterone; Randomized Controlled Trials as Topic; Thyroid Gland | 1994 |
RU486 (mifepristone): mechanisms of action and clinical uses.
Topics: Abortifacient Agents, Steroidal; Clinical Trials as Topic; Female; Genital Neoplasms, Female; Hormone Antagonists; Humans; Infant, Newborn; Male; Menstruation-Inducing Agents; Mifepristone; Neoplasms, Hormone-Dependent; Pregnancy; Receptors, Glucocorticoid; Receptors, Progesterone | 1997 |
Endocrine therapy in metastatic breast cancer.
Topics: Adult; Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estrogen Antagonists; Estrogens; Female; Gonadotropin-Releasing Hormone; Growth Substances; Hormone Antagonists; Humans; Menopause; Middle Aged; Mifepristone; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Palliative Care; Progestins; Receptors, Estrogen; Receptors, Growth Factor; Receptors, Progesterone; Tamoxifen | 1998 |
Progesterone receptors in breast cancer.
Topics: Animals; Breast Neoplasms; DNA-Binding Proteins; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Heat-Shock Proteins; Humans; Mifepristone; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Phosphorylation; Progesterone; Protein Conformation; Protein Processing, Post-Translational; Receptors, Glucocorticoid; Receptors, Progesterone; Regulatory Sequences, Nucleic Acid; Signal Transduction; Tumor Cells, Cultured | 1992 |
[Progesterone antagonists--pharmacology and perspectives of use].
Topics: Abortion, Induced; Animals; Breast Neoplasms; Endometrial Neoplasms; Female; Humans; Infant, Newborn; Luteal Phase; Mifepristone; Neoplasms, Hormone-Dependent; Pregnancy; Progesterone; Tumor Cells, Cultured | 1992 |
Anti-progesterones in obstetrics, ectopic pregnancies and gynaecological malignancy.
Topics: Animals; Cervix Uteri; Estrenes; Female; Humans; Labor, Induced; Macaca fascicularis; Mifepristone; Neoplasms, Hormone-Dependent; Pregnancy; Pregnancy, Ectopic; Receptors, Progesterone | 1988 |
Hormone dependence of breast tissue estradiol and progesterone interaction.
Topics: 17-Hydroxysteroid Dehydrogenases; Animals; Breast; Breast Neoplasms; Cells, Cultured; Estradiol; Estrenes; Female; Humans; Mice; Mifepristone; Neoplasms, Hormone-Dependent; Progesterone; Reference Values | 1987 |
Progestin action and progesterone receptor structure in human breast cancer: a review.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Affinity Labels; Animals; Antibodies, Monoclonal; Breast Neoplasms; Cells, Cultured; Chickens; Chromatography, DEAE-Cellulose; Estrenes; Female; Humans; Lipid Metabolism; Mammary Neoplasms, Experimental; Mifepristone; Molecular Weight; Neoplasms, Hormone-Dependent; Oviducts; Progestins; Rats; Receptor, Insulin; Receptors, Estrogen; Receptors, Glucocorticoid; Receptors, Progesterone | 1985 |
2 trial(s) available for mifepristone and Hormone-Dependent Neoplasms
| Article | Year |
|---|---|
Phase 2 trial of mifepristone (RU-486) in advanced or recurrent endometrioid adenocarcinoma or low-grade endometrial stromal sarcoma.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Endometrioid; Female; Hormone Antagonists; Humans; Middle Aged; Mifepristone; Neoplasms, Hormone-Dependent; Receptors, Progesterone; Recurrence; Sarcoma, Endometrial Stromal | 2009 |
A phase II study of mifepristone (RU-486) in castration-resistant prostate cancer, with a correlative assessment of androgen-related hormones.
Topics: Aged; Aged, 80 and over; Androgens; Antineoplastic Agents, Hormonal; Castration; Cell Communication; Disease Progression; Hormone Antagonists; Humans; Male; Middle Aged; Mifepristone; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Treatment Outcome | 2008 |
13 other study(ies) available for mifepristone and Hormone-Dependent Neoplasms
| Article | Year |
|---|---|
Syntheses and antigestagenic activity of mifepristone derivatives.
Topics: Alkaline Phosphatase; Breast Neoplasms; Cell Line, Tumor; Female; Hormone Antagonists; Humans; Mifepristone; Models, Molecular; Neoplasms, Hormone-Dependent; Receptors, Progesterone; Regression Analysis; Structure-Activity Relationship | 2009 |
Lack of synergy between estrogen and progesterone on local IGF-I, IGFBP-3 and IGFBP-2 secretion by both hormone-dependent and hormone-independent breast cancer explants in vitro. Effect of tamoxifen and mifepristone (RU 486).
Topics: Breast Neoplasms; Drug Synergism; Estradiol; Female; Humans; Insulin-Like Growth Factor Binding Protein 2; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Mifepristone; Neoplasms, Hormone-Dependent; Progesterone; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Tissue Culture Techniques | 2005 |
Progestin-dependent progression of human breast tumor xenografts: a novel model for evaluating antitumor therapeutics.
Topics: Angiogenesis Inhibitors; Animals; Aza Compounds; Breast Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; Cell Growth Processes; Disease Progression; Female; Humans; Medroxyprogesterone Acetate; Mice; Mifepristone; Neoplasms, Hormone-Dependent; Neovascularization, Pathologic; Progesterone; Progesterone Congeners; Progestins; Receptors, Estrogen; Receptors, Progesterone; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays | 2007 |
Meningiomas, epidermal growth factor and progesterone.
Topics: Adult; Aged; Cell Division; DNA Replication; Epidermal Growth Factor; ErbB Receptors; Female; Humans; Male; Meningeal Neoplasms; Meningioma; Middle Aged; Mifepristone; Neoplasms, Hormone-Dependent; Progesterone; Receptors, Progesterone; Tumor Cells, Cultured | 1994 |
Antiprogestin inhibition of cell cycle progression in T-47D breast cancer cells is accompanied by induction of the cyclin-dependent kinase inhibitor p21.
Topics: Breast Neoplasms; Cell Cycle; Cell Division; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Drug Resistance; Estrenes; Furans; Hormone Antagonists; Humans; Mifepristone; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Oncogene Proteins; Phosphorylation; Progestins; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Retinoblastoma Protein; Tumor Cells, Cultured | 1997 |
Additive effect of mifepristone and tamoxifen on apoptotic pathways in MCF-7 human breast cancer cells.
Topics: Apoptosis; Blotting, Western; Breast Neoplasms; DNA Fragmentation; Down-Regulation; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Estrogen Antagonists; Female; Hormone Antagonists; Humans; Mifepristone; Neoplasms, Hormone-Dependent; Protein Kinase C; Proto-Oncogene Proteins c-bcl-2; Tamoxifen; Transforming Growth Factor beta; Tumor Cells, Cultured | 1998 |
Progesterone receptor involvement in independent tumor growth in MPA-induced murine mammary adenocarcinomas.
Topics: Adenocarcinoma; Androgens; Animals; Binding Sites; Estradiol; Female; Flutamide; Glucocorticoids; Gonanes; Hormone Antagonists; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice; Mice, Inbred BALB C; Mifepristone; Neoplasms, Hormone-Dependent; Oligonucleotides, Antisense; Ovariectomy; Receptors, Estrogen; Receptors, Progesterone; Thymidine; Tumor Cells, Cultured | 1999 |
Effect of mifepristone approval on research remains to be seen.
Topics: Abortifacient Agents, Steroidal; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Drug Approval; Drug Industry; Female; France; Germany; Humans; Male; Mifepristone; Neoplasms, Hormone-Dependent; Ovarian Neoplasms; Progesterone; Prostatic Neoplasms; Research Support as Topic; Tamoxifen; United States; United States Food and Drug Administration | 2000 |
Hormonal modulation of HER-2/neu protooncogene messenger ribonucleic acid and p185 protein expression in human breast cancer cell lines.
Topics: Breast Neoplasms; Estrogen Antagonists; Estrogens; Humans; Mifepristone; Neoplasms, Hormone-Dependent; Progestins; Prognosis; Promegestone; Proto-Oncogene Proteins; Pyrrolidines; Receptor, ErbB-2; RNA, Messenger; RNA, Neoplasm; Thiophenes; Tumor Cells, Cultured | 1990 |
Progesterone augments proliferation induced by epidermal growth factor in a feline mammary adenocarcinoma cell line.
Topics: Adenocarcinoma; Animals; Cat Diseases; Cats; Cell Division; DNA Replication; Drug Synergism; Epidermal Growth Factor; ErbB Receptors; Female; Mammary Neoplasms, Animal; Mifepristone; Neoplasms, Hormone-Dependent; Phosphorylation; Progesterone; Progestins; Promegestone; Receptors, Progesterone; Tumor Cells, Cultured | 1991 |
Antitumor activity of the progesterone antagonists ZK 98.299 and RU 38.486 in the hormone-dependent MXT mammary tumor model of the mouse and the DMBA- and the MNU-induced mammary tumor models of the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estrenes; Female; Gonanes; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mifepristone; Neoplasms, Hormone-Dependent; Progesterone; Rats; Rats, Inbred Strains | 1989 |
Hormone dependency of meningiomas.
Topics: Aged; Estrenes; Female; Glucocorticoids; Humans; In Vitro Techniques; Meningeal Neoplasms; Meningioma; Mifepristone; Neoplasms, Hormone-Dependent; Receptors, Progesterone | 1989 |
[Progestogen therapy in the treatment of endometrial cancer--clinical results and mechanism of steroid action].
Topics: Estrenes; Female; Humans; In Vitro Techniques; Medroxyprogesterone; Medroxyprogesterone Acetate; Mifepristone; Neoplasms, Hormone-Dependent; Norethindrone; Norgestrel; Progesterone Congeners; Receptors, Progesterone; Tumor Stem Cell Assay; Uterine Neoplasms | 1988 |