Page last updated: 2024-08-23

mifepristone and Fibroid

mifepristone has been researched along with Fibroid in 79 studies

Research

Studies (79)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	16 (20.25)	18.2507
2000's	19 (24.05)	29.6817
2010's	35 (44.30)	24.3611
2020's	9 (11.39)	2.80

Authors

Authors	Studies
Bi, C; Jia, Y; Qiao, M; Wang, H	1
Chae, B; Kim, MR; Park, JY	1
Li, Q; Zhou, G	1
Bai, Y; Dong, T; Gao, F; Lei, Y; Li, M; Ou, L; Wei, P; Yang, H; Yang, L	1
Chen, X; Deng, G; Liu, R; Xuan, J; Zheng, Y	1
Shen, Q; Sheng, B; Sun, LZ; Zhao, M; Zhu, X; Zou, S	1
Bulun, SE; Coon V, JS; Dai, Y; Dotts, AJ; Kujawa, SA; Liu, S; Shilatifard, A; Xu, J; Yin, P; Zhao, H	1
Peng, F; Shi, S; Ye, Q; Yu, C	2
Dong, X; Guo, R; Hai, N; Hou, Q	1
Chow, TL; Murji, A; Sobel, ML; Whitaker, L	1
Hu, X; Luo, H; Shen, Q; Shu, L; Zhu, X	1
Bing, X; Ying, J	1
Belland, L; Leyland, N; Murji, A; Singh, SS; von Riedemann, S	1
Bouchard, P; Chabbert-Buffet, N; Daraï, E; Kolanska, K	1
Cui, S; Feng, Q; Liu, P; Wang, Z; Zhang, L	1
Cardini, F; Liu, JP; Xia, Y; Yang, H	2
Driák, D; Sehnal, B; Svandová, I	1
Agarwal, N; Garg, P; Hari, S; Kriplani, A; Kulshrestha, V; Sareen, N; Thulkar, J	1
Chen, M; Hua, Y; Jiang, W; Shen, Q; Zhang, W; Zhu, X	1
Davies, H; Fang, M; Hu, Z; Sun, Y	1
Gilboa, Y; Goldchmit, C; Jakobson-Setton, A; Katz, D; Seidman, DS; Tadir, Y; Yerushalmi, GM	1
Byström, B; Engman, M; Gemzell-Danielsson, K; Hammarsjö, A; Lagerstedt Robinson, K; Lalitkumar, PG; Malmgren, H; Varghese, S	1
Chen, NN; Han, M; Liu, JP; Wang, YY; Wu, XK; Yang, GY; Yang, H	1
Bastianelli, C; Benagiano, G; Brosens, I; Farris, M	1
Frisk, AL; Fritsch, M; Gröticke, I; Keator, CS; Koch, M; Schmidt, N; Slayden, OD	1
Abraham, T; Arian, SE; Bartels, CB; Cayton, KC; Chuong, FS; Holthouser, K; Segars, JH	1
Britten, J; Catherino, WH; Cox, J; Malik, M; Patel, A	1
Centini, G; Kashani, BN; Morelli, SS; Petraglia, F; Weiss, G	1
Bragg, B; Chawla, K; Hladky, K; Mark, K	1
Bian, M; Geng, L; Huang, M; Liu, C; Lu, Q; Qu, H; Wang, H; Wen, Z; Zhang, Y; Zhang, Z; Zheng, S	1
Branchini, G; Brum, IS; Capp, E; Corleta, HVE; Pizzolato, LS; Sant'Anna, GDS	1
Akerman, G; Barranger, E; Desfeux, P; Malartic, C; Morel, O; Tulpin, L	1
Eisinger, S; Fiscella, K	1
Bouchard, P; Chabbert-Buffet, N; Ouzounian, S	1
Berry, E; Bulun, S; Chakravarti, D; Clardy, J; Hardt, J; Hoekstra, AV; Kim, JJ; Lu, Z; Marsh, E; Sefton, EC; Yin, P	1
Erenbourg, A; Piccoli, M; Ronfani, L; Tamburlini, G	1
Engman, M; Gemzell-Danielsson, K; Granberg, S; Lalitkumar, PG; Meng, CX; Williams, AR	1
Fraser, IS	1
Bonfiglio, T; Eisinger, SH; Fiscella, J; Fiscella, K; Meldrum, S	1
Spitz, IM	2
Bulun, SE; Ishikawa, H; Lin, Z; Luo, X; Marsh, EE; Pavone, ME; Reierstad, S; Yin, P; Zhao, H	1
Bulun, SE; Chakravarti, D; Cheng, Y; Coon, JS; Innes, J; Ishikawa, H; Kim, JJ; Lin, Z; Marsh, EE; Pearson, K; Reierstad, S; Wu, J; Yin, P	1
Feng, C; Fiscella, K; Meldrum, S	1
Bulun, SE; Ishi, K; Ishikawa, H; Kakazu, R; Kurita, T; Serna, VA	1
Bulun, SE; Coon, JS; Ishikawa, H; Pearson, EK; Su, E	1
Csatlós, E; Joó, JG; Nagy, Z; Rigó, J; Szabó, I	1
Bonfiglio, T; Eisinger, SH; Fiscella, J; Fiscella, K; Winters, P	1
Bouchard, P	1
Acosta, R; Campos, R; Esteve, JL; Hernández, AV; Pérez, Y; Texidó, CS	1
Bulun, SE; Coon, JS; Dai, Y; Huang, L; Kim, JJ; Monsivais, D; Navarro, A; Owen, JK; Roqueiro, D; Xie, A; Yin, P	1
Angiolucci, M; Guerriero, S; Lello, S; Maricosu, G; Marotto, MF; Melis, GB; Orru', MM; Paoletti, AM; Pilloni, M; Piras, B	1
Orozco, LJ; Ramírez-Morera, A; Steed, A; Stone, P; Tristan, M	1
Manyonda, I; Talaulikar, VS	1
Schweppe, KW	1
Chegini, N; Ma, C; Tang, XM; Williams, RS	1
Eisinger, SH; Fiscella, K; Guzick, DS; le Roux, HD; Meldrum, S	1
Jackson, R; Jacoby, AF; Pritts, EA; Steinauer, J	1
Dominguez, CE; Lowe, E; Murphy, AA; Parthasarathy, S; Ramachandran, S; Song, MQ	1
Kettel, LM; Morales, AJ; Murphy, AA; Yen, SS	1
Castellano, PZ; Murphy, AA	1
Morales, AJ; Murphy, AA; Reinsch, RC; Yen, SS	1
Smith, SK	1
Kettel, LM; Morales, AJ; Murphy, AA; Roberts, VJ; Yen, SS	1
Kettel, LM	1
Austin, DJ; Jain, P; Nowak, RA; Penglase, MD; Stewart, EA	1
Kettel, LM; Morales, AJ; Murphy, AA	1
Heikinheimo, O	1
Li, K; Yang, Y; Zheng, S	1
London, SN; Mahajan, DK	1
Yang, Y; Zhang, Z; Zheng, S	1
Sun, M; Zhou, L; Zhu, G	1
Gu, M; Huang, H; Zeng, C	1
Boettger-Tong, H; Chiappetta, C; Huang, JC; Hyder, SM; Mäkelä, S; Nawaz, Z; Stancel, GM	1
Weng, L	1
Jin, J; Wang, H	1
Jiang, J; Sun, HC; Wang, ZH; Wu, RF; Xiu, HM; Xu, Z	1

Reviews

28 review(s) available for mifepristone and Fibroid

Article	Year
The efficacy and safety of Chinese herbal medicine Guizhi Fuling capsule combined with low dose mifepristone in the treatment of uterine fibroids: a systematic review and meta-analysis of 28 randomized controlled trials. BMC complementary medicine and therapies, 2023, Feb-18, Volume: 23, Issue:1 Topics: Drugs, Chinese Herbal; Female; Humans; Leiomyoma; Mifepristone; Randomized Controlled Trials as Topic; Wolfiporia	2023
The efficacy and safety of Xuefu Zhuyu Decoction combined with Mifepristone in the treatment of uterine leiomyoma: A systematic review and meta-analysis. Journal of ethnopharmacology, 2021, Dec-05, Volume: 281 Topics: Antineoplastic Agents; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Humans; Leiomyoma; Mifepristone; Uterine Neoplasms	2021
Selective progesterone receptor modulators (SPRMs) for uterine fibroids. The Cochrane database of systematic reviews, 2017, Apr-26, Volume: 4 Topics: Amenorrhea; Antineoplastic Agents, Hormonal; Estrenes; Female; Humans; Leiomyoma; Leuprolide; Menstruation; Mifepristone; Norpregnadienes; Oximes; Pelvic Pain; Quality of Life; Randomized Controlled Trials as Topic; Receptors, Progesterone; Uterine Neoplasms	2017
The past, present, and future of selective progesterone receptor modulators in the management of uterine fibroids. American journal of obstetrics and gynecology, 2018, Volume: 218, Issue:6 Topics: Contraceptive Agents, Female; Disease Management; Estrenes; Female; Forecasting; Humans; Leiomyoma; Mifepristone; Norpregnadienes; Oximes; Population Growth; Receptors, Progesterone; Steroids; Uterine Neoplasms	2018
Selective progesterone receptor modulators: current applications and perspectives. Climacteric : the journal of the International Menopause Society, 2018, Volume: 21, Issue:4 Topics: Abortion, Induced; Endometriosis; Female; Humans; Leiomyoma; Mifepristone; Norpregnadienes; Pregnancy; Progesterone; Receptors, Progesterone; Uterine Hemorrhage; Uterine Neoplasms	2018
Herbal preparations for uterine fibroids. The Cochrane database of systematic reviews, 2013, Apr-30, Issue:4 Topics: Drugs, Chinese Herbal; Female; Gonadotropin-Releasing Hormone; Hormone Antagonists; Humans; Leiomyoma; Mifepristone; Phytotherapy; Plant Preparations; Randomized Controlled Trials as Topic; Uterine Neoplasms	2013
Effects of mifepristone on uterine leiomyoma in premenopausal women: a meta-analysis. Fertility and sterility, 2013, Volume: 100, Issue:6 Topics: Antineoplastic Agents; Drug-Related Side Effects and Adverse Reactions; Evidence-Based Medicine; Female; Humans; Incidence; Leiomyoma; Mifepristone; Premenopause; Risk Factors; Treatment Outcome; Uterine Neoplasms	2013
Mifepristone: a potential clinical agent based on its anti-progesterone and anti-glucocorticoid properties. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2014, Volume: 30, Issue:3 Topics: Abortifacient Agents, Steroidal; Antidepressive Agents; Contraceptives, Oral, Synthetic; Contraceptives, Postcoital, Synthetic; Cushing Syndrome; Endometriosis; Female; Humans; Hyperglycemia; Hypoglycemic Agents; Leiomyoma; Male; Mifepristone; Mood Disorders; Receptors, Glucocorticoid; Receptors, Progesterone	2014
Chinese herbal medicine Guizhi Fuling Formula for treatment of uterine fibroids: a systematic review of randomised clinical trials. BMC complementary and alternative medicine, 2014, Jan-02, Volume: 14 Topics: Bias; China; Complementary Therapies; Drug Therapy, Combination; Drugs, Chinese Herbal; Dysmenorrhea; Female; Humans; Leiomyoma; Mifepristone; Phytotherapy; Randomized Controlled Trials as Topic	2014
Selective progesterone receptor modulators: an update. Expert opinion on pharmacotherapy, 2014, Volume: 15, Issue:10 Topics: Adenomyosis; Animals; Clinical Trials as Topic; Contraception, Postcoital; Contraceptive Agents, Female; Contraceptives, Postcoital; Endometriosis; Estrenes; Female; Hormone Antagonists; Humans; Leiomyoma; Levonorgestrel; Mifepristone; Norpregnadienes; Oximes; Receptors, Progesterone; Uterine Neoplasms	2014
An Evidence-based Approach to the Medical Management of Fibroids: A Systematic Review. Clinical obstetrics and gynecology, 2016, Volume: 59, Issue:1 Topics: Androgens; Aromatase Inhibitors; Contraceptive Agents, Female; Contraceptives, Oral, Combined; Curcumin; Delayed-Action Preparations; Drugs, Chinese Herbal; Estradiol; Estrenes; Estrogen Receptor Antagonists; Evidence-Based Medicine; Female; Fulvestrant; Gonadotropin-Releasing Hormone; Hormone Antagonists; Humans; Intrauterine Devices, Medicated; Leiomyoma; Levonorgestrel; Medroxyprogesterone Acetate; Mifepristone; Neoadjuvant Therapy; Norpregnadienes; Oximes; Plant Extracts; Receptors, Progesterone; Selective Estrogen Receptor Modulators; Tea; Uterine Myomectomy; Uterine Neoplasms; Vitamin D; Vitamins	2016
Role of Medical Management for Uterine Leiomyomas. Best practice & research. Clinical obstetrics & gynaecology, 2016, Volume: 34 Topics: Antifibrinolytic Agents; Aromatase Inhibitors; Cabergoline; Cholecalciferol; Contraceptive Agents, Female; Contraceptives, Oral, Hormonal; Contraceptives, Oral, Synthetic; Danazol; Dopamine Agonists; Ergolines; Estrenes; Estrogen Antagonists; Female; Gestrinone; Gonadotropin-Releasing Hormone; Humans; Intrauterine Devices, Medicated; Leiomyoma; Levonorgestrel; Mifepristone; Norpregnadienes; Oximes; Patient Care Planning; Selective Estrogen Receptor Modulators; Somatostatin; Tranexamic Acid; Uterine Neoplasms; Vitamins	2016
[Role of mifepristone for the treatment of uterine fibroid]. Gynecologie, obstetrique & fertilite, 2008, Volume: 36, Issue:6 Topics: Antineoplastic Agents, Hormonal; Dose-Response Relationship, Drug; Endometrial Hyperplasia; Female; Hot Flashes; Humans; Leiomyoma; Liver; Mifepristone; Treatment Outcome; Uterine Neoplasms	2008
Effects of antiprogestins on the uterus. Women's health (London, England), 2008, Volume: 4, Issue:3 Topics: Animals; Contraceptives, Oral, Synthetic; Female; Hormone Antagonists; Humans; Leiomyoma; Metrorrhagia; Mifepristone; Progestins; Receptors, Progesterone; Uterine Neoplasms; Uterus	2008
Herbal preparations for uterine fibroids. The Cochrane database of systematic reviews, 2009, Apr-15, Issue:2 Topics: Drugs, Chinese Herbal; Female; Gonadotropin-Releasing Hormone; Hormone Antagonists; Humans; Leiomyoma; Mifepristone; Phytotherapy; Plant Preparations; Randomized Controlled Trials as Topic	2009
Clinical utility of progesterone receptor modulators and their effect on the endometrium. Current opinion in obstetrics & gynecology, 2009, Volume: 21, Issue:4 Topics: Drug Administration Schedule; Endometriosis; Endometrium; Estrenes; Female; Hormone Antagonists; Humans; Leiomyoma; Mifepristone; Norpregnadienes; Oximes; Randomized Controlled Trials as Topic; Receptors, Progesterone; Time Factors; Uterine Neoplasms	2009
[Uterine leiomyoma]. Orvosi hetilap, 2010, Oct-17, Volume: 151, Issue:42 Topics: Antineoplastic Agents; Diagnosis, Differential; Estrenes; Female; Hormone Antagonists; Humans; Hysterectomy; Incidence; Laparoscopy; Leiomyoma; Mifepristone; Oximes; Ultrasonic Therapy; Uterine Artery; Uterine Neoplasms	2010
Current and future medical treatments for menometrorrhagia during the premenopause. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2011, Volume: 27 Suppl 1 Topics: Adolescent; Adult; Contraceptives, Oral; Endometrial Neoplasms; Female; Gonadotropin-Releasing Hormone; Humans; Leiomyoma; Levonorgestrel; Menorrhagia; Metrorrhagia; Mifepristone; Norpregnadienes; Polyps; Premenopause; Progestins; Randomized Controlled Trials as Topic; Receptors, Progesterone; Uterine Neoplasms	2011
Mifepristone for uterine fibroids. The Cochrane database of systematic reviews, 2012, Aug-15, Issue:8 Topics: Female; Humans; Leiomyoma; Menorrhagia; Mifepristone; Premenopause; Randomized Controlled Trials as Topic; Receptors, Progesterone; Tumor Burden; Uterine Neoplasms	2012
Progesterone and progesterone receptor modulators in the management of symptomatic uterine fibroids. European journal of obstetrics, gynecology, and reproductive biology, 2012, Volume: 165, Issue:2 Topics: Endometrium; Estrenes; Female; Hormone Antagonists; Humans; Hyperplasia; Intrauterine Devices, Medicated; Leiomyoma; Levonorgestrel; Mifepristone; Norpregnadienes; Oximes; Receptors, Progesterone	2012
Progestins and uterine leiomyoma. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 1999, Volume: 13 Suppl 4 Topics: Danazol; Estrogen Antagonists; Estrogens; Female; Gonadotropin-Releasing Hormone; Hormone Antagonists; Humans; Leiomyoma; Mifepristone; Progesterone; Progestins; Uterine Neoplasms	1999
Progesterone antagonists and progesterone receptor modulators. Expert opinion on investigational drugs, 2003, Volume: 12, Issue:10 Topics: Animals; Contraceptives, Postcoital; Drug Administration Schedule; Endometriosis; Endometrium; Female; Gene Transfer Techniques; Hormone Antagonists; Humans; Leiomyoma; Mifepristone; Progesterone; Receptors, Progesterone; Uterine Neoplasms	2003
Systematic review of mifepristone for the treatment of uterine leiomyomata. Obstetrics and gynecology, 2004, Volume: 103, Issue:6 Topics: Adult; Clinical Trials as Topic; Endometrial Hyperplasia; Female; Hormone Antagonists; Humans; Leiomyoma; Middle Aged; Mifepristone; Uterine Neoplasms	2004
RU486: pharmacology and potential use in the treatment of endometriosis and leiomyomata uteri. Current opinion in obstetrics & gynecology, 1994, Volume: 6, Issue:3 Topics: Endometriosis; Endometrium; Female; Humans; Leiomyoma; Mifepristone; Progesterone; Uterine Neoplasms	1994
Clinical applications of the antiprogestins. Clinical obstetrics and gynecology, 1995, Volume: 38, Issue:4 Topics: Abortifacient Agents, Steroidal; Breast Neoplasms; Clinical Trials as Topic; Contraceptives, Oral, Synthetic; Cushing Syndrome; Endometriosis; Endometrium; Female; Hormone Antagonists; Humans; Leiomyoma; Meningeal Neoplasms; Meningioma; Menstrual Cycle; Mifepristone; Pregnancy; Pregnancy, Ectopic; Premenstrual Syndrome; Progestins; Uterine Neoplasms	1995
Mifepristone: clinical application in general gynecology. Clinical obstetrics and gynecology, 1996, Volume: 39, Issue:2 Topics: Endometriosis; Endometrium; Female; Genital Diseases, Female; Hormone Antagonists; Humans; Leiomyoma; Menstrual Cycle; Mifepristone; Uterine Neoplasms	1996
Mifepristone (RU486): a review. Fertility and sterility, 1997, Volume: 68, Issue:6 Topics: Abortifacient Agents, Steroidal; Abortion, Induced; Animals; Breast Neoplasms; Contraceptives, Oral, Synthetic; Contraceptives, Postcoital, Synthetic; Endometriosis; Female; Humans; Leiomyoma; Mifepristone; Pregnancy; Uterine Neoplasms	1997
Regulation of vascular endothelial growth factor expression by estrogens and progestins. Environmental health perspectives, 2000, Volume: 108 Suppl 5 Topics: Breast Neoplasms; Dose-Response Relationship, Drug; Endothelial Growth Factors; Estradiol; Estrogen Antagonists; Estrogens; Female; Fulvestrant; Gene Expression Regulation; Hormone Antagonists; Humans; Leiomyoma; Lymphokines; Mifepristone; Progestins; Receptors, Estrogen; RNA, Messenger; Signal Transduction; Transcription, Genetic; Uterine Neoplasms; Uterus; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	2000

Trials

13 trial(s) available for mifepristone and Fibroid

Article	Year
Low dose mifepristone in medical management of uterine leiomyoma - an experience from a tertiary care hospital from north India. The Indian journal of medical research, 2013, Volume: 137, Issue:6 Topics: Administration, Oral; Adult; Cost-Benefit Analysis; Drug Administration Schedule; Female; Follow-Up Studies; Hormone Antagonists; Humans; India; Leiomyoma; Menorrhagia; Middle Aged; Mifepristone; Prospective Studies; Tertiary Care Centers; Treatment Outcome; Uterine Neoplasms	2013
Vaginal mifepristone for the treatment of symptomatic uterine leiomyomata: an open-label study. Fertility and sterility, 2014, Volume: 101, Issue:2 Topics: Administration, Intravaginal; Adult; Female; Hormone Antagonists; Humans; Israel; Leiomyoma; Middle Aged; Mifepristone; Prospective Studies; Surveys and Questionnaires; Treatment Outcome; Uterine Neoplasms	2014
GSTM1 gene expression correlates to leiomyoma volume regression in response to mifepristone treatment. PloS one, 2013, Volume: 8, Issue:12 Topics: Biomarkers; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glutathione Transferase; Hormone Antagonists; Humans; Leiomyoma; Mifepristone; Oligonucleotide Array Sequence Analysis; Premenopause; Receptors, Progesterone; Signal Transduction; Tumor Burden; Uterine Neoplasms; Uterus	2013
Different dosages of mifepristone versus enantone to treat uterine fibroids: A multicenter randomized controlled trial. Medicine, 2017, Volume: 96, Issue:7 Topics: Adult; Amenorrhea; Antineoplastic Agents, Hormonal; Dose-Response Relationship, Drug; Dysmenorrhea; Female; Hematologic Tests; Hormone Antagonists; Humans; Leiomyoma; Leuprolide; Middle Aged; Mifepristone	2017
Mifepristone for treatment of uterine leiomyoma. A prospective randomized placebo controlled trial. Human reproduction (Oxford, England), 2009, Volume: 24, Issue:8 Topics: Adult; Double-Blind Method; Female; Hemoglobins; Humans; Leiomyoma; Middle Aged; Mifepristone; Regional Blood Flow; Uterine Hemorrhage; Uterine Neoplasms; Uterus	2009
Open-label study of ultra low-dose mifepristone for the treatment of uterine leiomyomata. European journal of obstetrics, gynecology, and reproductive biology, 2009, Volume: 146, Issue:2 Topics: Administration, Oral; Adult; Dose-Response Relationship, Drug; Female; Health Status; Hormone Antagonists; Humans; Leiomyoma; Middle Aged; Mifepristone; Pain; Quality of Life; Uterine Hemorrhage; Uterine Neoplasms	2009
Treatment of uterine myoma with 5 or 10mg mifepristone daily during 6 months, post-treatment evolution over 12 months: double-blind randomised clinical trial. European journal of obstetrics, gynecology, and reproductive biology, 2012, Volume: 161, Issue:2 Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Double-Blind Method; Fatigue; Female; Follow-Up Studies; Hemoglobins; Hormone Antagonists; Hot Flashes; Humans; Leiomyoma; Menorrhagia; Middle Aged; Mifepristone; Nausea; Pelvic Pain; Uterine Neoplasms; Vomiting	2012
Low-dose mifepristone for uterine leiomyomata. Obstetrics and gynecology, 2003, Volume: 101, Issue:2 Topics: Adult; Biopsy, Needle; Blood Chemical Analysis; Dose-Response Relationship, Drug; Drug Administration Schedule; Endosonography; Female; Follow-Up Studies; Hormone Antagonists; Humans; Immunohistochemistry; Leiomyoma; Middle Aged; Mifepristone; Multivariate Analysis; Reference Values; Statistics, Nonparametric; Treatment Outcome; Uterine Neoplasms	2003
Clinical efficacy of the antiprogesterone RU486 in the treatment of endometriosis and uterine fibroids. Human reproduction (Oxford, England), 1994, Volume: 9 Suppl 1 Topics: Abdominal Pain; Adolescent; Adrenocorticotropic Hormone; Adult; Anovulation; Endometriosis; Estrogens; Female; Humans; Hydrocortisone; Leiomyoma; Luteinizing Hormone; Mifepristone; Pilot Projects; Progesterone; Ultrasonography; Uterine Neoplasms	1994
The effects of RU 486 and leuprolide acetate on uterine artery blood flow in the fibroid uterus: a prospective, randomized study. American journal of obstetrics and gynecology, 1994, Volume: 170, Issue:6 Topics: Female; Humans; Leiomyoma; Leuprolide; Mifepristone; Prospective Studies; Regional Blood Flow; Uterine Neoplasms; Uterus	1994
[Treatment of uterine leiomyoma by two different doses of mifepristone]. Zhonghua fu chan ke za zhi, 1996, Volume: 31, Issue:10 Topics: Adult; Female; Hormone Antagonists; Humans; Leiomyoma; Middle Aged; Mifepristone; Prospective Studies; Uterine Neoplasms	1996
[Effects of mifepristone on gene expression of epidermal growth factor in human uterine leiomyoma]. Zhonghua fu chan ke za zhi, 1998, Volume: 33, Issue:1 Topics: Epidermal Growth Factor; Female; Gene Expression; Hormone Antagonists; Humans; Leiomyoma; Mifepristone; RNA, Messenger; Uterine Neoplasms	1998
[A clinical control study on the treatment of uterine leiomyoma with gonadotrophin releasing hormone agonist or mifepristone]. Zhonghua fu chan ke za zhi, 1998, Volume: 33, Issue:8 Topics: Adult; Female; Gonadotropin-Releasing Hormone; Hormone Antagonists; Humans; Leiomyoma; Middle Aged; Mifepristone; Uterine Neoplasms	1998

Other Studies

38 other study(ies) available for mifepristone and Fibroid

Article	Year
Network meta-analysis of 6 kinds of Chinese patent medicines combined with mifepristone in the treatment of uterine fibroids: A protocol for systematic review and network meta-analysis. Medicine, 2021, Oct-22, Volume: 100, Issue:42 Topics: Drug Therapy, Combination; Hormone Antagonists; Humans; Leiomyoma; Medicine, Chinese Traditional; Meta-Analysis as Topic; Mifepristone; Network Meta-Analysis; Randomized Controlled Trials as Topic; Research Design; Systematic Review as Topic	2021
The Potential of Transforming Growth Factor-beta Inhibitor and Vascular Endothelial Growth Factor Inhibitor as Therapeutic Agents for Uterine Leiomyoma. International journal of medical sciences, 2022, Volume: 19, Issue:12 Topics: Female; Humans; Intercellular Signaling Peptides and Proteins; Leiomyoma; Mifepristone; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transforming Growth Factors; Uterine Neoplasms; Vascular Endothelial Growth Factor A	2022
Long-term use of ultra-low-dose mifepristone for uterine leiomyoma control and safety discussion: A case report. Medicine, 2022, Dec-30, Volume: 101, Issue:52 Topics: Female; Hormone Antagonists; Humans; Leiomyoma; Menstrual Cycle; Middle Aged; Mifepristone; Uterine Neoplasms	2022
Analysis of medication data of women with uterine fibroids based on data mining technology. Journal of infection and public health, 2020, Volume: 13, Issue:10 Topics: Data Mining; Female; Humans; Leiomyoma; Medicine, Chinese Traditional; Mifepristone; Technology	2020
Mifepristone inhibits IGF-1 signaling pathway in the treatment of uterine leiomyomas. Drug design, development and therapy, 2019, Volume: 13 Topics: Adult; Antineoplastic Agents; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Female; Humans; Insulin-Like Growth Factor I; Leiomyoma; Mifepristone; Signal Transduction; Tumor Cells, Cultured; Uterine Neoplasms	2019
Targeting DNA Methylation Depletes Uterine Leiomyoma Stem Cell-enriched Population by Stimulating Their Differentiation. Endocrinology, 2020, 10-01, Volume: 161, Issue:10 Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Count; Cell Differentiation; Cells, Cultured; DNA Methylation; Female; Humans; Leiomyoma; Mice; Mice, SCID; Mice, Transgenic; Middle Aged; Mifepristone; Molecular Targeted Therapy; Neoplastic Stem Cells; Uterine Neoplasms; Xenograft Model Antitumor Assays	2020
The efficacy and safety of Xuefu Zhuyu Decoction combined Mifepristone in the treatment of Uterine leiomyoma: A protocol systematic review and meta-analysis. Medicine, 2021, Jan-22, Volume: 100, Issue:3 Topics: Clinical Protocols; Drugs, Chinese Herbal; Hormone Antagonists; Humans; Leiomyoma; Meta-Analysis as Topic; Mifepristone; Systematic Reviews as Topic	2021
Comparison between radiofrequency ablation combined with mifepristone and radiofrequency ablation for large uterine fibroids. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 2021, Volume: 38, Issue:1 Topics: Female; Humans; Leiomyoma; Mifepristone; Quality of Life; Radiofrequency Ablation; Retrospective Studies; Treatment Outcome; Uterine Neoplasms	2021
The use of mifepristone in abortion associated with an increased risk of uterine leiomyomas. Medicine, 2017, Volume: 96, Issue:17 Topics: Abortion, Induced; Adult; Case-Control Studies; Dose-Response Relationship, Drug; Educational Status; Female; Humans; Leiomyoma; Logistic Models; Menstruation; Middle Aged; Mifepristone; Multivariate Analysis; Odds Ratio; Parity; Retrospective Studies; Risk Factors; Surveys and Questionnaires; Uterine Neoplasms; Vaginitis; Young Adult	2017
Chemical constituents of Cyperus rotundus L. and their inhibitory effects on uterine fibroids. African health sciences, 2016, Volume: 16, Issue:4 Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Biflavonoids; Cyperus; Disease Models, Animal; Estradiol; Female; Flavones; Leiomyoma; Mifepristone; Plant Extracts; Progesterone; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar	2016
Progesterone receptor antagonist provides palliative effects for uterine leiomyoma through a Bcl-2/Beclin1-dependent mechanism. Bioscience reports, 2019, 07-31, Volume: 39, Issue:7 Topics: Adult; Apoptosis; Autophagic Cell Death; Beclin-1; Female; Humans; Leiomyoma; Middle Aged; Mifepristone; Palliative Care; Proto-Oncogene Proteins c-bcl-2; Receptors, Progesterone; Uterine Neoplasms	2019
[Selective progesterone receptor modulators and their therapeutical use]. Ceska gynekologie, 2013, Volume: 78, Issue:2 Topics: Abortion, Induced; Endometriosis; Female; Hormone Antagonists; Humans; Leiomyoma; Mifepristone; Norpregnadienes; Pregnancy; Progesterone; Receptors, Progesterone	2013
Application of a Patient Derived Xenograft Model for Predicative Study of Uterine Fibroid Disease. PloS one, 2015, Volume: 10, Issue:11 Topics: Animals; Disease Models, Animal; Estrogen Receptor alpha; Estrogens; Female; Heterografts; Humans; Leiomyoma; Mice; Mice, SCID; Mifepristone; Receptors, Progesterone	2015
Mifepristone inhibits extracellular matrix formation in uterine leiomyoma. Fertility and sterility, 2016, Volume: 105, Issue:4 Topics: Cell Line, Transformed; Dose-Response Relationship, Drug; Extracellular Matrix; Female; Hormone Antagonists; Humans; Leiomyoma; Mifepristone; Promegestone; Tumor Cells, Cultured; Uterine Neoplasms	2016
Medical abortion in women with large uterine fibroids: a case series. Contraception, 2016, Volume: 94, Issue:5 Topics: Abortifacient Agents; Abortion, Induced; Administration, Intravaginal; Adult; Drug Administration Schedule; Female; Gestational Age; Humans; Leiomyoma; Maryland; Mifepristone; Misoprostol; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Trimester, First; Pregnancy Trimester, Second; Uterine Neoplasms	2016
Ovarian steroid hormones modulate the expression of progesterone receptors and histone acetylation patterns in uterine leiomyoma cells. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2017, Volume: 33, Issue:8 Topics: Adult; Cells, Cultured; Estradiol; Estrogens; Female; Gene Expression Regulation, Neoplastic; Histone Acetyltransferases; Histone Deacetylases; Hormone Antagonists; Humans; Leiomyoma; Middle Aged; Mifepristone; Myometrium; Neoplasm Proteins; Progesterone; Progestins; Receptors, Progesterone; Tumor Cells, Cultured; Uterine Neoplasms	2017
CDB-2914 for uterine leiomyomata treatment: a randomized controlled trial. Obstetrics and gynecology, 2008, Volume: 112, Issue:3 Topics: Female; Hormone Antagonists; Humans; Leiomyoma; Mifepristone; Norpregnadienes; Quality of Life; Randomized Controlled Trials as Topic; Uterine Neoplasms	2008
Progestins activate the AKT pathway in leiomyoma cells and promote survival. The Journal of clinical endocrinology and metabolism, 2009, Volume: 94, Issue:5 Topics: Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Survival; Female; Fluorescent Antibody Technique; Forkhead Box Protein O1; Forkhead Transcription Factors; Humans; Leiomyoma; Mifepristone; Oncogene Protein v-akt; Phosphorylation; Progestins; Promegestone; Signal Transduction; Uterine Neoplasms	2009
Mifepristone for the treatment of uterine leiomyomas: methodological issues and clinical implications. Obstetrics and gynecology, 2009, Volume: 113, Issue:3 Topics: Female; Hormone Antagonists; Humans; Leiomyoma; Mifepristone; Organ Size; Uterine Neoplasms; Uterus	2009
Re: Low-dose mifepristone: Effects on the endometrium. Aust N Z J Obstet Gynaecol 2009; 49: 77-83. The Australian & New Zealand journal of obstetrics & gynaecology, 2009, Volume: 49, Issue:3 Topics: Endometrium; Female; Hormone Antagonists; Humans; Leiomyoma; Menorrhagia; Mifepristone; Uterine Neoplasms	2009
Progesterone and mifepristone regulate L-type amino acid transporter 2 and 4F2 heavy chain expression in uterine leiomyoma cells. The Journal of clinical endocrinology and metabolism, 2009, Volume: 94, Issue:11 Topics: Adult; Amino Acid Transport System y+; Cell Survival; DNA Primers; Female; Follicular Phase; Fusion Regulatory Protein 1, Heavy Chain; Fusion Regulatory Protein 1, Light Chains; Gene Expression Regulation, Neoplastic; Humans; Leiomyoma; Luteal Phase; Menstruation; Middle Aged; Mifepristone; Polymerase Chain Reaction; Progesterone; RNA, Messenger; RNA, Neoplasm; RNA, Small Interfering; Uterine Neoplasms	2009
Transcription factor KLF11 integrates progesterone receptor signaling and proliferation in uterine leiomyoma cells. Cancer research, 2010, Feb-15, Volume: 70, Issue:4 Topics: Apoptosis Regulatory Proteins; Cell Cycle Proteins; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Hormone Antagonists; Humans; Leiomyoma; Mifepristone; Progesterone; Promoter Regions, Genetic; Receptors, Progesterone; Repressor Proteins; Signal Transduction; Trans-Activators; Transcription Factors; Tumor Burden; Tumor Cells, Cultured; Uterine Neoplasms	2010
Improved quality of life is partly explained by fewer symptoms after treatment of fibroids with mifepristone. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2010, Volume: 109, Issue:2 Topics: Adult; Anemia; Female; Hormone Antagonists; Humans; Leiomyoma; Middle Aged; Mifepristone; Organ Size; Pain; Quality of Life; Randomized Controlled Trials as Topic; Ultrasonography; Uterine Neoplasms; Uterus	2010
Progesterone is essential for maintenance and growth of uterine leiomyoma. Endocrinology, 2010, Volume: 151, Issue:6 Topics: Animals; Estradiol; Estrogen Receptor alpha; Female; Humans; Immunohistochemistry; In Situ Nick-End Labeling; In Vitro Techniques; Leiomyoma; Mice; Mifepristone; Myometrium; Progesterone; Receptors, Progesterone; Transplantation, Heterologous; Uterine Neoplasms	2010
LAT1 regulates growth of uterine leiomyoma smooth muscle cells. Reproductive sciences (Thousand Oaks, Calif.), 2010, Volume: 17, Issue:9 Topics: Adult; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Female; Hormone Antagonists; Humans; Large Neutral Amino Acid-Transporter 1; Leiomyoma; Middle Aged; Mifepristone; Myocytes, Smooth Muscle; Myometrium; Progesterone; RNA Interference; RNA, Messenger; Uterine Neoplasms	2010
Distinguishing features of endometrial pathology after exposure to the progesterone receptor modulator mifepristone. Human pathology, 2011, Volume: 42, Issue:7 Topics: Adult; Endometrium; Female; Hormone Antagonists; Humans; Leiomyoma; Middle Aged; Mifepristone; Receptors, Progesterone; Uterine Neoplasms	2011
Genome-wide progesterone receptor binding: cell type-specific and shared mechanisms in T47D breast cancer cells and primary leiomyoma cells. PloS one, 2012, Volume: 7, Issue:1 Topics: Adult; Base Sequence; Binding Sites; Breast Neoplasms; Cell Line, Tumor; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genome, Human; Hormone Antagonists; Humans; Leiomyoma; Membrane Proteins; Middle Aged; Mifepristone; Nucleotide Motifs; Oligonucleotide Array Sequence Analysis; Perilipin-2; Position-Specific Scoring Matrices; Receptors, Progesterone; Response Elements; Tumor Cells, Cultured; Uterine Neoplasms	2012
Pharmacokinetic evaluation of ulipristal acetate for uterine leiomyoma treatment. Expert opinion on drug metabolism & toxicology, 2012, Volume: 8, Issue:7 Topics: Adult; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Drug Evaluation, Preclinical; Female; Hormone Antagonists; Humans; Leiomyoma; Menorrhagia; Mifepristone; Norpregnadienes; Progesterone; Receptors, Progesterone; Uterine Neoplasms	2012
Effects of GnRH analogues, 'add-back' steroid therapy, antiestrogen and antiprogestins on leiomyoma and myometrial smooth muscle cell growth and transforming growth factor-beta expression. Molecular human reproduction, 2002, Volume: 8, Issue:12 Topics: Estradiol; Estrogen Receptor Modulators; Female; Gonadotropin-Releasing Hormone; Gonanes; Humans; Leiomyoma; Leuprolide; Medroxyprogesterone Acetate; Mifepristone; Muscle Development; Myocytes, Smooth Muscle; Myometrium; Oligopeptides; Progestins; Steroids; Transforming Growth Factors	2002
RU486 inhibits expression of lysophosphatidic acid induced glycodelin. American journal of obstetrics and gynecology, 2005, Volume: 192, Issue:4 Topics: Adult; Base Sequence; Biopsy, Needle; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation, Neoplastic; Glycoproteins; Humans; Immunohistochemistry; Leiomyoma; Lysophospholipids; Middle Aged; Mifepristone; Molecular Sequence Data; Probability; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; Sensitivity and Specificity; Tumor Cells, Cultured; Uterine Neoplasms	2005
The regulation of fibroid growth: time for a re-think? British journal of obstetrics and gynaecology, 1993, Volume: 100, Issue:11 Topics: Estradiol; Female; Gonadotropin-Releasing Hormone; Humans; Leiomyoma; Mifepristone; Pregnancy; Progesterone; Uterine Neoplasms	1993
Regression of uterine leiomyomata in response to the antiprogesterone RU 486. The Journal of clinical endocrinology and metabolism, 1993, Volume: 76, Issue:2 Topics: Adolescent; Adult; Androstenedione; Bone Density; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Follicle Stimulating Hormone; Humans; Hysterectomy; Immunohistochemistry; Leiomyoma; Luteinizing Hormone; Middle Aged; Mifepristone; Myometrium; Progesterone; Receptors, Estradiol; Receptors, Progesterone; Testosterone; Uterine Neoplasms	1993
RU486 suppresses prolactin production in explant cultures of leiomyoma and myometrium. Fertility and sterility, 1996, Volume: 65, Issue:6 Topics: Culture Media; Estradiol; Female; Humans; Hysterectomy; Immunohistochemistry; L-Lactate Dehydrogenase; Leiomyoma; Menstrual Cycle; Mifepristone; Myometrium; Progesterone; Prolactin; Tumor Cells, Cultured	1996
Clinical pharmacokinetics of mifepristone. Clinical pharmacokinetics, 1997, Volume: 33, Issue:1 Topics: Abortifacient Agents, Steroidal; Abortion, Induced; Breast Neoplasms; Contraception; Endometriosis; Female; Humans; Labor, Induced; Leiomyoma; Meningioma; Mifepristone; Pregnancy; Progestins	1997
[Effect of mifepristone on the expression of progesterone receptor messenger RNA and protein in uterine leiomyomata]. Zhonghua fu chan ke za zhi, 1998, Volume: 33, Issue:4 Topics: Adult; Female; Gene Expression; Humans; Leiomyoma; Middle Aged; Mifepristone; Receptors, Progesterone; RNA, Messenger; Uterine Neoplasms	1998
[Clinical application of mifepristone in obstetrics and gynecology]. Zhonghua fu chan ke za zhi, 1999, Volume: 34, Issue:5 Topics: Abortifacient Agents, Steroidal; Contraceptives, Postcoital, Synthetic; Endometriosis; Female; Humans; Leiomyoma; Mifepristone; Pregnancy; Uterine Neoplasms	1999
[Effects of mifepristone on estrogen and progestin receptors in human uterine leiomyoma]. Zhonghua fu chan ke za zhi, 2000, Volume: 35, Issue:2 Topics: Adult; Female; Hormone Antagonists; Humans; Leiomyoma; Middle Aged; Mifepristone; Receptors, Estrogen; Receptors, Progesterone; Uterine Neoplasms	2000
Effect of mifepristone on estrogen and progesterone receptors in human endometrial and endometriotic cells in vitro. Fertility and sterility, 2002, Volume: 77, Issue:5 Topics: Adult; Cells, Cultured; Dose-Response Relationship, Drug; Down-Regulation; Endometriosis; Endometrium; Female; Follicular Phase; Hormone Antagonists; Humans; Immunohistochemistry; Leiomyoma; Luteal Phase; Mifepristone; Osmolar Concentration; Prospective Studies; Receptors, Estrogen; Receptors, Progesterone; Uterine Neoplasms	2002