Page last updated: 2024-08-23

mifepristone and Experimental Mammary Neoplasms

mifepristone has been researched along with Experimental Mammary Neoplasms in 32 studies

Research

Studies (32)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (28.13)	18.7374
1990's	10 (31.25)	18.2507
2000's	8 (25.00)	29.6817
2010's	5 (15.63)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chwalisz, K; Cleve, A; Fritzemeier, KH; Fuhrmann, U; Hess-Stumpp, H; Hoffmann, J; Neef, G; Schwede, W	1
Allen, MC; Bucca, G; Falcinelli, M; Flaherty, RL; Flint, MS; Hesketh, A; Intabli, H; Patel, BA; Smith, CP	1
Giulianelli, S; Gorostiaga, MA; Jacobsen, B; Lanari, C; May, M; Molinolo, A; Novaro, V; Polo, ML; Riggio, M; Rojas, P; Sequeira, GR; Wargon, V	1
Choi, MR; Christov, K; Ivancic, D; Khan, SA; Lee, O	1
Cong, MH; Sun, JZ; Tian, XS; Wu, GJ; Zhou, WH	1
Bolado, J; Helguero, LA; Lanari, C; Molinolo, A; Novaro, V; Rojas, P; Wargon, V	1
Fernandez, SV; Giulianelli, S; Goin, M; Lanari, C; Russo, J; Wargon, V	1
Glazer, RI; Kopelovich, L; Lu, J; Upadhyay, G; Yuan, H	1
Agarwal, R; Bhatia, N; Jiang, W; Thompson, HJ; Zhu, Z	1
Charreau, EH; Coso, OA; Elizalde, PV; Kornblihtt, AR; Labriola, L; Pecci, A; Proietti, CJ; Salatino, M	1
Colombo, L; Lanari, C; Meiss, R; Molinolo, AA; Soldati, R; Vanzulli, SI	1
Benakanakere, I; Besch-Williford, C; Brandt, S; Ellersieck, MR; Hyder, SM; Molinolo, A; Schnell, J	1
Christov, K; Mehta, R; Wiehle, RD	1
Charreau, EH; Dran, G; Lanari, C; Luthy, IA; Molinolo, AA; Montecchia, F; Pasqualini, CD	1
Deckers, GH; Kloosterboer, HJ; Schoonen, WG	1
Archer, TK; Mymryk, JS	1
Charreau, E; Lamb, C; Lanari, C; Luthy, IA; Molinolo, AA; Montecchia, MF; Pazos, P; Vanzulli, S	1
Gehring, S; Kühnel, W; Michna, H; Nishino, Y; Schneider, MR	1
Hirose, T; Lu, J; Matsumoto, K; Nishizawa, Y; Sato, B; Tanaka, A	1
el Etreby, MF; McGuire, WL; Michna, H; Nishino, Y; Schneider, M	1
Permezel, M	1
el Etreby, MF; Michna, H; Nishino, Y; Schneider, MR	4
Firestone, GL; Guthrie, J; Webster, MK	1
Bakker, GH; De Jong, FH; Foekens, JA; Klijn, JG; Portengen, H; Setyono-Han, B	1
Baulieu, EE; Jung-Testas, I	1
Jordan, VC; Robinson, SP	1
Bakker, GH; de Jong, FH; Henkelman, MS; Klijn, JG; Lamberts, SW; Setyono-Han, B; van der Schoot, P	1
Gompel, A; Kuttenn, F; Mauvais-Jarvis, P	1
d'Arville, CN; Horwitz, KB; Sedlacek, SM; Wei, LL	1

Reviews

4 review(s) available for mifepristone and Experimental Mammary Neoplasms

Article	Year
The antiprogesterone steroid, RU 486 (mifepristone). The Australian & New Zealand journal of obstetrics & gynaecology, 1990, Volume: 30, Issue:1 Topics: Abortion, Therapeutic; Animals; Female; Humans; Labor, Induced; Lactation; Macaca fascicularis; Mammary Neoplasms, Experimental; Mifepristone; Pregnancy; Rats	1990
Antitumor activity and mechanism of action of different antiprogestins in experimental breast cancer models. The Journal of steroid biochemistry and molecular biology, 1990, Dec-20, Volume: 37, Issue:6 Topics: Animals; Antineoplastic Agents; Cell Cycle; Gonanes; Kinetics; Mammary Neoplasms, Experimental; Mifepristone; Progesterone	1990
Antiestrogen action of progesterone in breast tissue. Breast cancer research and treatment, 1986, Volume: 8, Issue:3 Topics: 17-Hydroxysteroid Dehydrogenases; Adenoma; Animals; Breast; Cell Division; Cells, Cultured; Estradiol; Estrenes; Estrogen Antagonists; Estrogens; Female; Humans; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mifepristone; Progesterone; Progestins; Promegestone; Receptors, Estrogen	1986
Progestin action and progesterone receptor structure in human breast cancer: a review. Recent progress in hormone research, 1985, Volume: 41 Topics: 9,10-Dimethyl-1,2-benzanthracene; Affinity Labels; Animals; Antibodies, Monoclonal; Breast Neoplasms; Cells, Cultured; Chickens; Chromatography, DEAE-Cellulose; Estrenes; Female; Humans; Lipid Metabolism; Mammary Neoplasms, Experimental; Mifepristone; Molecular Weight; Neoplasms, Hormone-Dependent; Oviducts; Progestins; Rats; Receptor, Insulin; Receptors, Estrogen; Receptors, Glucocorticoid; Receptors, Progesterone	1985

Other Studies

28 other study(ies) available for mifepristone and Experimental Mammary Neoplasms

Article	Year
Synthesis and biological activity of a novel, highly potent progesterone receptor antagonist. Journal of medicinal chemistry, 2000, Dec-28, Volume: 43, Issue:26 Topics: Abortifacient Agents; Adrenalectomy; Androgen Antagonists; Animals; Antineoplastic Agents; Binding, Competitive; Castration; Cell Line; Estrenes; Female; Glucocorticoids; Gonanes; Hormone Antagonists; Ligands; Male; Mammary Neoplasms, Experimental; Mifepristone; Progesterone; Protein Isoforms; Rabbits; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Androgen; Receptors, Estrogen; Receptors, Glucocorticoid; Receptors, Progesterone; Transcriptional Activation	2000
Stress hormone-mediated acceleration of breast cancer metastasis is halted by inhibition of nitric oxide synthase. Cancer letters, 2019, 09-10, Volume: 459 Topics: Animals; Breast Neoplasms; Cell Line, Tumor; DNA Damage; Drug Interactions; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Hydrocortisone; Lung Neoplasms; Mammary Neoplasms, Experimental; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mifepristone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Reactive Nitrogen Species; Reactive Oxygen Species; Stress, Psychological	2019
Progestin and antiprogestin responsiveness in breast cancer is driven by the PRA/PRB ratio via AIB1 or SMRT recruitment to the CCND1 and MYC promoters. International journal of cancer, 2015, Jun-01, Volume: 136, Issue:11 Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Female; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Mifepristone; Nuclear Receptor Co-Repressor 2; Nuclear Receptor Coactivator 3; Progestins; Promoter Regions, Genetic; Proto-Oncogene Proteins c-myc; Receptors, Progesterone	2015
Progesterone receptor antagonism inhibits progestogen-related carcinogenesis and suppresses tumor cell proliferation. Cancer letters, 2016, 07-01, Volume: 376, Issue:2 Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiogenesis Inhibitors; Animals; Antigens, CD34; Antineoplastic Agents, Hormonal; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Female; Hormone Antagonists; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Methylnitrosourea; Mice; Mifepristone; Neovascularization, Pathologic; Norpregnadienes; Progesterone; Progestins; Rats; Receptors, Estrogen; Receptors, Progesterone; Time Factors	2016
[Inhibitive effects of mifepristone on growth of breast cancer: experiment with animal model]. Zhonghua yi xue za zhi, 2008, Feb-26, Volume: 88, Issue:8 Topics: Animals; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Female; Hormone Antagonists; Humans; Immunohistochemistry; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Mifepristone; Neovascularization, Pathologic; Random Allocation; Receptors, Estrogen; Receptors, Progesterone; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays	2008
Reversal of antiprogestin resistance and progesterone receptor isoform ratio in acquired resistant mammary carcinomas. Breast cancer research and treatment, 2009, Volume: 116, Issue:3 Topics: Animals; Blotting, Western; Cell Proliferation; Drug Resistance, Neoplasm; Female; Fluorescent Antibody Technique; Hormone Antagonists; Lymphatic Metastasis; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mifepristone; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Protein Isoforms; Proto-Oncogene Proteins c-akt; Receptors, Progesterone; Survival Rate	2009
Hypermethylation of the progesterone receptor A in constitutive antiprogestin-resistant mouse mammary carcinomas. Breast cancer research and treatment, 2011, Volume: 126, Issue:2 Topics: Animals; Apoptosis; Azacitidine; Cell Culture Techniques; Cell Line, Tumor; Coculture Techniques; Decitabine; DNA Methylation; DNA Modification Methylases; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Hormone Antagonists; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mifepristone; Mitosis; Neoplasm Transplantation; Promoter Regions, Genetic; Receptors, Glucocorticoid; Receptors, Progesterone; Transplantation, Heterologous; Tumor Burden	2011
The chemopreventive effect of mifepristone on mammary tumorigenesis is associated with an anti-invasive and anti-inflammatory gene signature. Cancer prevention research (Philadelphia, Pa.), 2012, Volume: 5, Issue:5 Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Hormonal; Carcinogens; Carcinoma; Chemoprevention; Drug Evaluation, Preclinical; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Hormone Antagonists; Inflammation; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Microarray Analysis; Mifepristone; Neoplasm Invasiveness; Paired Box Transcription Factors; PAX8 Transcription Factor	2012
Mechanisms of energy restriction: effects of corticosterone on cell growth, cell cycle machinery, and apoptosis. Cancer research, 2002, Sep-15, Volume: 62, Issue:18 Topics: Animals; Cell Cycle; Cell Cycle Proteins; Cell Division; Corticosterone; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Energy Intake; Hyperplasia; Insulin-Like Growth Factor I; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mifepristone; Proto-Oncogene Proteins; Tumor Suppressor Proteins	2002
Heregulin induces transcriptional activation of the progesterone receptor by a mechanism that requires functional ErbB-2 and mitogen-activated protein kinase activation in breast cancer cells. Molecular and cellular biology, 2003, Volume: 23, Issue:3 Topics: Animals; Breast Neoplasms; Cell Division; Cell Nucleus; Enzyme Inhibitors; Female; Flavonoids; Genes, erbB-2; Hormone Antagonists; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mifepristone; Mitogen-Activated Protein Kinases; Neuregulin-1; Phosphorylation; Receptor, ErbB-2; Receptors, Progesterone; RNA, Messenger; RNA, Neoplasm; Transcriptional Activation; Tumor Cells, Cultured	2003
Estrogen or antiprogestin treatment induces complete regression of pulmonary and axillary metastases in an experimental model of breast cancer progression. Carcinogenesis, 2005, Volume: 26, Issue:6 Topics: Animals; Apoptosis; Cell Cycle Proteins; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Estradiol; Estrogens; Female; Lung Neoplasms; Lymphatic Metastasis; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mifepristone; Mitosis; Progestins; Receptors, Estrogen; Receptors, Progesterone; Transplantation, Heterologous; Tumor Suppressor Proteins	2005
Natural and synthetic progestins accelerate 7,12-dimethylbenz[a]anthracene-initiated mammary tumors and increase angiogenesis in Sprague-Dawley rats. Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Jul-01, Volume: 12, Issue:13 Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Implants; Immunohistochemistry; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mifepristone; Neovascularization, Pathologic; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, Progesterone; Time Factors; Vascular Endothelial Growth Factors	2006
Anti-progestins suppress the growth of established tumors induced by 7,12-dimethylbenz(a)anthracene: comparison between RU486 and a new 21-substituted-19-nor-progestin. Oncology reports, 2007, Volume: 18, Issue:1 Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Proliferation; Disease Progression; Female; Hormone Antagonists; Mammary Neoplasms, Experimental; Mifepristone; Norpregnadienes; Progesterone Congeners; Progestins; Rats; Rats, Sprague-Dawley	2007
Effect of medroxyprogesterone acetate (MPA) and serum factors on cell proliferation in primary cultures of an MPA-induced mammary adenocarcinoma. Breast cancer research and treatment, 1995, Volume: 35, Issue:2 Topics: Adenocarcinoma; Androgen Antagonists; Animals; Blood Physiological Phenomena; Cell Division; Dexamethasone; Dihydrotestosterone; Estradiol; Female; Flutamide; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice; Mice, Inbred BALB C; Mifepristone; Ovariectomy; Progesterone; Tumor Cells, Cultured	1995
Pharmacology of two new very selective antiprogestagens: Org 31710 and Org 31806. Human reproduction (Oxford, England), 1994, Volume: 9 Suppl 1 Topics: 9,10-Dimethyl-1,2-benzanthracene; Abortifacient Agents, Steroidal; Abortion, Induced; Androgen Antagonists; Animals; Estrenes; Female; Furans; Gonanes; Macaca; Male; Mammary Neoplasms, Experimental; Menstruation-Inducing Agents; Mifepristone; Pregnancy; Progestins; Rats; Receptors, Glucocorticoid; Receptors, Progesterone	1994
Influence of hormone antagonists on chromatin remodeling and transcription factor binding to the mouse mammary tumor virus promoter in vivo. Molecular endocrinology (Baltimore, Md.), 1995, Volume: 9, Issue:12 Topics: Animals; Binding, Competitive; Chromatin; Dexamethasone; Glucocorticoids; Gonanes; Hormone Antagonists; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mifepristone; Promoter Regions, Genetic; Receptors, Glucocorticoid; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured	1995
Progesterone receptor involvement in independent tumor growth in MPA-induced murine mammary adenocarcinomas. The Journal of steroid biochemistry and molecular biology, 1999, Volume: 68, Issue:1-2 Topics: Adenocarcinoma; Androgens; Animals; Binding Sites; Estradiol; Female; Flutamide; Glucocorticoids; Gonanes; Hormone Antagonists; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice; Mice, Inbred BALB C; Mifepristone; Neoplasms, Hormone-Dependent; Oligonucleotides, Antisense; Ovariectomy; Receptors, Estrogen; Receptors, Progesterone; Thymidine; Tumor Cells, Cultured	1999
The antitumor potency of progesterone antagonists is due to their differentiation potential. The Journal of steroid biochemistry and molecular biology, 1992, Volume: 43, Issue:1-3 Topics: Animals; Antineoplastic Agents; Cell Differentiation; Gonanes; Mammary Neoplasms, Experimental; Mice; Mifepristone; Progesterone; Rats	1992
Non-classical androgenic actions of RU38486 in androgen-responsive Shionogi carcinoma 115 cells in serum-free culture. The Journal of steroid biochemistry and molecular biology, 1991, Volume: 39, Issue:3 Topics: Animals; Cell Division; Culture Media, Serum-Free; Dexamethasone; DNA, Neoplasm; Drug Interactions; Flutamide; Glucocorticoids; Mammary Neoplasms, Experimental; Mice; Mifepristone; Testosterone; Triamcinolone Acetonide; Tumor Cells, Cultured	1991
Progesterone antagonists block the growth of experimental mammary tumors in G0/G1. Breast cancer research and treatment, 1990, Volume: 17, Issue:2 Topics: Animals; Antineoplastic Agents; Cell Division; Female; G1 Phase; Gonanes; Mammary Neoplasms, Experimental; Mifepristone; Progesterone; Rats; Rats, Inbred Strains; Resting Phase, Cell Cycle	1990
Suppression of rat mammary tumor cell growth in vitro by glucocorticoids requires serum proteins. Characterization of wild type and glucocorticoid-resistant epithelial tumor cells. The Journal of biological chemistry, 1990, Mar-25, Volume: 265, Issue:9 Topics: Animals; Antigens, Neoplasm; Blood Proteins; Cell Division; Cell Line; Clone Cells; Culture Media; Dexamethasone; DNA Replication; Drug Resistance; Epithelial Cells; Epithelium; Genetic Vectors; Humans; Mammary Neoplasms, Experimental; Membrane Glycoproteins; Mifepristone; Mucin-1; Rats; Receptors, Glucocorticoid; Transfection; Tumor Cells, Cultured	1990
Antitumor activity of the progesterone antagonists ZK 98.299 and RU 38.486 in the hormone-dependent MXT mammary tumor model of the mouse and the DMBA- and the MNU-induced mammary tumor models of the rat. European journal of cancer & clinical oncology, 1989, Volume: 25, Issue:4 Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estrenes; Female; Gonanes; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mifepristone; Neoplasms, Hormone-Dependent; Progesterone; Rats; Rats, Inbred Strains	1989
Antitumor activity of the antiprogestins ZK 98.299 and RU 38.486 in hormone dependent rat and mouse mammary tumors: mechanistic studies. Breast cancer research and treatment, 1989, Volume: 14, Issue:3 Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Female; Gonanes; Mammary Neoplasms, Experimental; Methylnitrosourea; Mifepristone; Neoplasm Transplantation; Organ Size; Ovariectomy; Ovary; Rats; Rats, Inbred Strains; Uterus; Vagina	1989
Endocrine and antitumor effects of combined treatment with an antiprogestin and antiestrogen or luteinizing hormone-releasing hormone agonist in female rats bearing mammary tumors. Endocrinology, 1989, Volume: 125, Issue:3 Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Buserelin; Cytosol; Drug Implants; Estrenes; Female; Follicle Stimulating Hormone; Goserelin; Injections, Subcutaneous; Luteinizing Hormone; Mammary Neoplasms, Experimental; Mifepristone; Progestins; Rats; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen	1989
The antitumor mechanism of progesterone antagonists is a receptor mediated antiproliferative effect by induction of terminal cell death. Journal of steroid biochemistry, 1989, Volume: 34, Issue:1-6 Topics: Animals; Antineoplastic Agents; Cell Division; Cell Line; Cell Survival; Estradiol; Female; Gonanes; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Mifepristone; Ovariectomy; Progesterone; Tumor Cells, Cultured	1989
Effects of steroid hormones and antihormones in cultured cells. Experimental and clinical endocrinology, 1985, Volume: 86, Issue:2 Topics: Animals; Cell Division; Cells, Cultured; Cyproterone; Cyproterone Acetate; Dexamethasone; Diethylstilbestrol; Dihydrotestosterone; Estradiol; Estrenes; Glucocorticoids; Gonadal Steroid Hormones; L Cells; Mammary Neoplasms, Experimental; Mice; Mifepristone; Receptors, Androgen; Receptors, Estrogen; Receptors, Glucocorticoid; Tamoxifen; Thymoma	1985
Reversal of the antitumor effects of tamoxifen by progesterone in the 7,12-dimethylbenzanthracene-induced rat mammary carcinoma model. Cancer research, 1987, Oct-15, Volume: 47, Issue:20 Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Drug Interactions; Estradiol; Estrenes; Estrogens; Estrone; Mammary Neoplasms, Experimental; Mifepristone; Organ Size; Progesterone; Rats; Tamoxifen	1987
Comparison of the actions of the antiprogestin mifepristone (RU486), the progestin megestrol acetate, the LHRH analog buserelin, and ovariectomy in treatment of rat mammary tumors. Cancer treatment reports, 1987, Volume: 71, Issue:11 Topics: Animals; Body Weight; Buserelin; Combined Modality Therapy; Estrenes; Female; Follicle Stimulating Hormone; Luteinizing Hormone; Mammary Neoplasms, Experimental; Megestrol; Megestrol Acetate; Mifepristone; Ovariectomy; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone	1987