mifepristone has been researched along with Disease Models, Animal in 190 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.53) | 18.7374 |
| 1990's | 19 (10.00) | 18.2507 |
| 2000's | 75 (39.47) | 29.6817 |
| 2010's | 80 (42.11) | 24.3611 |
| 2020's | 15 (7.89) | 2.80 |
| Authors | Studies |
|---|---|
| Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ | 1 |
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Alves, BO; de Oliveira, D; de Oliveira, PV; Morgan, LV; Müller, LG; Oltramari, AR; Petry, F; Scapinello, J; Scatolin, M; Volfe, CRB; Zilli, GAL | 1 |
| Alves, T; Andrade, L; Cardoso, A; Dulce Madeira, M; Pereira, PA; Rocha, R; Sá, S | 1 |
| da Silva Junior, ED; Gavioli, EC; Holanda, VAD; Oliveira, MC | 1 |
| Check, D; Check, JH | 1 |
| Han, Y; Liu, J; Mao, Y; Mu, H; Wang, H; Xu, L; Zhang, D | 1 |
| Cheng, PY; Hsiao, M; Lin, CC; Liu, YP | 1 |
| Lin, T; Xu, J; Yang, L | 1 |
| Chen, L; Jiang, Y; Kang, Y; Pan, J; Sun, J; Tang, D; Xu, W; Ye, H; Zhou, M; Zhu, J | 1 |
| Haghparast, A; Hesam, S; Karimi, S; Karimi-Haghighi, S; Razavi, Y | 1 |
| Akiba, N; Fujii, T; Iriyama, T; Kawana, K; Kumasawa, K; Nagamatsu, T; Osuga, Y; Samejima, T; Sayama, S; Taguchi, A | 1 |
| Chen, Y; Luo, J; Qi, Q; Wang, Y; Xie, Q | 1 |
| Bast, RC; Cheon, DJ; Cho, CH; Coffey, DM; DeMayo, FJ; Emerson, RE; Fernández, FM; Godwin, AK; Hawkins, SM; Karpf, AR; Kim, J; Kim, O; Kwon, SY; Lydon, JP; Miller, KD; Nephew, KP; Park, EY; Quilliam, LA; Shin, S; Shin, YH; Sood, AK; Widschwendter, M | 1 |
| Datta, K; Kumar, S; Saha, P; Tyagi, RK | 1 |
| Bosland, MC; Clare, SE; Helenowski, I; Hosseini, O; Khan, SA; Kim, JJ; Lee, O; Patel, P; Schipma, MJ; Shidfar, A; Wang, M; Xuei, X | 1 |
| Chen, Y; Hu, J; Huang, L; Ke, Z; Lu, H; Xie, L; Zheng, J; Zheng, X | 1 |
| Bing, X; Ying, J | 1 |
| Cao, L; Du, J; Jia, R; Kitazawa, T; Kubota, A; Teraoka, H; Yin, G | 1 |
| Akirav, I; Shoshan, N | 1 |
| Jiang, H; Liu, D; Liu, Y; Pan, F; Wang, R; Xu, J | 1 |
| Joshi, S; Kapur, J; Perez-Reyes, E; Rajasekaran, K; Sun, H; Williamson, J | 1 |
| Hasegawa, S; Hida, H; Ito, T; Kunimoto, S; Mouri, A; Nabeshima, T; Noda, Y; Ozaki, N; Taniguchi, M; Uchida, M; Ukai, M; Yamada, K; Yoshimi, A | 1 |
| Baches, S; Krugers, HJ; Lesuis, SL; Lucassen, PJ; Weggen, S | 1 |
| Li, YY; Liu, BP; Liu, FM; Peng, ZL; Song, C; Wang, HY; Zhang, C; Zhang, YP | 1 |
| Bethea, JR; Jiang, J; Norden, DM | 1 |
| Bähr, M; Cheng, S; Déglon, N; Konstantinova, P; Kügler, S; Liefhebber, J; Mazur, A; Pythoud, C; Raina, A; Rey, M; Streit, F; Tereshchenko, J; Vachey, G; Zimmer, V | 1 |
| Bi, YH; Chen, JL; Jiang, DX; Sun, XH; Wang, SW; Wu, XJ | 1 |
| Du, M; Gu, Y; Huang, J; Jin, M; Wan, B; Xue, M; Ye, W; Yu, H; Zhang, J; Zhang, Y | 1 |
| Chen, X; da Silva, MS; Ding, J; Han, F; Lingeman, J; Meijer, OC; Shi, Y | 1 |
| Hattori, T; Iwase, E; Miyachi, M; Murase, T; Murohara, T; Nagata, K; Ohtake, M; Takahashi, K; Tsuboi, K | 1 |
| Kusaka, E; Senoo, N; Sugimoto, Y; Sugiyama, M; Yamamoto, A | 1 |
| Bratasz, A; Guan, Z; Huang, K; Mandrekar-Colucci, S; Nash, MS; Popovich, PG; Powell, ND; Rabchevsky, AG; Reader, B; Shawler, T; Sheridan, JF; Weil, Z; Wells, J; Whitacre, CC; Zhang, Y | 1 |
| Hasan, AU; Hashimoto, T; Igarashi, J; Kohno, M; Kosaka, H; Nagai, Y; Ohmori, K; Yamashita, T | 1 |
| Bähr, M; Kügler, S; Maddalena, A; Tereshchenko, J | 1 |
| Bhatt, AJ; Famuyide, M; Feng, Y | 1 |
| Attarzadeh-Yazdi, G; Azizi, P; Haghparast, A; Hesam, S; Karimi, S; Razavi, Y; Yazdi-Ravandi, S | 1 |
| Ait-Belgnaoui, A; Braniste, V; Gabanou, M; Houdeau, E; Martin, PG; Moussaoui, N; Olier, M; Sekkal, S; Théodorou, V | 1 |
| Anton, F; Hanesch, U; Le Coz, GM | 1 |
| Dobashi, K; Kikuchi, T; Kita, H; Miyasaka, T; Ohno, I; Okuyama, K; Sora, I; Takayanagi, M; Yamazaki, N | 1 |
| Averbeck, M; Lehmann, I; Petzold, S; Polte, T; Simon, JC | 1 |
| Bigio, B; McEwen, BS; Nasca, C; Nicoletti, F; Zelli, D | 1 |
| Chen, J; Jiang, L; Qian, W; Su, C; Wang, J; Xiao, H; Zhang, H; Zhang, J; Zhu, B | 1 |
| Fan, Z; Han, Y; Li, J; Liu, W; Mao, Y; Wang, H; Wang, M; Xu, L; Zhang, D | 1 |
| Barik, J; Bethus, I; Chafai, M; Kootar, S; Lanté, F; Marie, H; Mouska, X; Pereira, AR; Raymond, EF | 1 |
| Chijiwa, T; Lkhagvasuren, B; Oka, T; Sudo, N; Yoshihara, K | 1 |
| Hattori, T; Matsuura, N; Murohara, T; Nagasawa, K; Nagata, K; Takahashi, K; Takeshita, Y; Watanabe, S | 1 |
| Den Blaauwen, JL; Joëls, M; Loi, M; Lucassen, PJ; Meerhoff, GF; Mossink, JC | 1 |
| Bekker, A; Cao, J; Liang, L; Lutz, BM; Shieh, KR; Tao, YX; Wang, H; Wang, PK; Zhang, J | 1 |
| Frisk, AL; Fritsch, M; Gröticke, I; Keator, CS; Koch, M; Schmidt, N; Slayden, OD | 1 |
| Aono, H; Choudhury, ME; Fujita, T; Islam, A; Mise, A; Miyanishi, K; Nishioka, R; Sugimoto, K; Takahashi, H; Takeda, H; Tanaka, J; Yano, H | 1 |
| Antelmi, A; Armani, A; Caprio, M; Chlopicki, S; Cinti, F; Fabbri, A; Feraco, A; Hunt, H; Mammi, C; Marzolla, V; Maslak, E | 1 |
| Goto, M; Iwase, A; Kikkawa, F; Kondo, M; Kotani, T; Nakahara, T; Nakamura, T; Osuka, S; Saito, A | 1 |
| Chen, J; Dong, H; Jia, L; Liu, J; Lu, Y; Shao, J; Wang, J; Xiao, Y; Xie, J; Yu, S; Zheng, N; Zhu, Y | 1 |
| Chen, C; Chen, H; Chen, W; Dong, C; Liang, H; Liu, R; Liu, S; Nie, Z; Shi, P; Yang, R; Zhou, Z | 1 |
| Adaku, U; Dong, Y; Friedman, TC; Liu, Y; Lutfy, K; Tian, S; Wang, W; Wang, Y; Wu, Y; Yan, C; Yang, H; Yu, F | 1 |
| Ito, S; Matsuura, N; Murohara, T; Nagasawa, K; Nagata, K; Sano, Y; Takeshita, Y; Uchinaka, A; Yamada, Y | 1 |
| Chen, Z; Dong, Z; Ge, RS; Lian, Q; Liang, Y; Lin, W; Wang, B; Wang, S; Wu, B; Zhang, G | 1 |
| Chapman, KE; Hadoke, PW; MacRae, VE; Rashdan, NA; Zhu, D | 1 |
| Cheng, MH; Fan, BS; Han, B; Wu, ZT; Yu, JG; Zhang, EH | 1 |
| Chan, MT; Gerstner, JR; Lenz, O; Pack, AI; Pfeiffenberger, C; Vanderheyden, WM | 1 |
| Abe, N; Kumano, A; Takeuchi, K | 1 |
| Belanoff, JK; Canet, G; Chevallier, N; Desrumaux, C; Givalois, L; Hunt, H; Ollivier, M; Pineau, F | 1 |
| Fujita, M; Honda, K; Iwata, K; Kawata, A; Kimoto, S; Nagashima, H; Shinoda, M; Shoji, N; Takahashi, O; Watanabe, M; Yasuda, M | 1 |
| Fuchs, RA; Higginbotham, JA; Stringfield, SJ | 1 |
| Bhuiyan, MS; Fukunaga, K; Han, F; Hasegawa, H; Kanai, H; Shinoda, Y; Tagashira, H; Zhang, C | 1 |
| Brito, PS; Cabrini, DA; Facundo, VA; Favero, GM; Horinouchi, CD; Mendes, DA; Nolte, S; Otuki, MF; Santos, AR; Soley, BD | 1 |
| Ge, N; Liu, C; Zhai, JL; Zhang, JX | 1 |
| Bi, Y; Han, L; Hu, Y; Jia, A; Li, C; Li, Y; Liu, G; Liu, H; Lu, Y; Wang, J; Wang, R; Wang, Y; Yang, H; Zhang, Z; Zhao, Y | 1 |
| Alessandri-Haber, N; Bogen, O; Brown, AS; Burkham, J; Dina, OA; Green, PG; Khasar, SG; Levine, JD; Reichling, DB | 1 |
| Cai, W; Chen, L; Furuya, K; Li, Z; Sokabe, M; Zhu, Y | 1 |
| Cordeiro, RS; de O Barreto, E; e Silva, PM; Ferreira, TP; Lagente, V; Martins, MA; Oliveira, MS; Pires, AL; Wallace, JL; Zamuner, S | 1 |
| Liu, GY; Mi, RR; Qi, J; Qu, QX | 1 |
| Check, JH; Dix, E; Sansoucie, L | 1 |
| Gu, YT; Qin, LJ; Qin, X; Xu, F | 1 |
| Bechtold, AG; Hochhaus, G; Patel, G; Scheuer, DA | 1 |
| Canlon, B; Meltser, I; Tahera, Y | 1 |
| Priyadarshani, A | 1 |
| Bailey, MA; Kenyon, CJ; Mullins, JJ | 1 |
| Chai, J; Elovitz, MA; Gonzalez, JM; Ofori, E; Xu, H | 1 |
| Fujiwara, H; Kudo, Y; Miyoshi, H; Urabe, S; Yamaoka, K | 1 |
| Huang, GY; Wang, W; Wu, YX; Zheng, CH | 1 |
| Song, C; Taepavarapruk, P | 1 |
| Hodge, CW; Lowery, EG; Lyons, AM; Navarro, M; Spanos, M; Thiele, TE | 1 |
| Bao, J; Huang, L; Liu, K; Ma, G; Mei, L; Song, C; Sun, H; Sun, L; Tang, L; Wang, H; Yang, J; Zhang, C; Zhang, L | 1 |
| Bentz, AI; Burd, I; Chai, J; Cohen, AS; Elovitz, MA; Gonzalez, J; Le Roux, PD; Monnerie, H; Yudkoff, M | 1 |
| Cao, J; Duan, TT; Mao, RR; Tan, JW; Tian, M; Xu, L; Zhou, QX | 1 |
| Alamdari, N; Aversa, Z; Hasselgren, PO; Smith, IJ | 1 |
| Chen, M; Dasgupta, C; Xue, Q; Zhang, L | 1 |
| Hong, S; Owyang, C; Snider, NT; Wiley, JW; Wu, X; Zheng, G | 1 |
| Ling, D; Salvaterra, PM | 1 |
| Beckley, EH; Finn, DA; Scibelli, AC | 1 |
| Baldi, A; Cerliani, JP; Giulianelli, S; Gongora, A; Lamb, CE; Lanari, C; Molinolo, A; Sahores, A; Wargon, V | 1 |
| Azroyan, A; Bloch-Faure, M; Crambert, G; Doucet, A; Edwards, A; Elabida, B; Fodstad, H; Meneton, P; Salhi, A | 1 |
| Gu, X; Liu, C; Ma, Q; Ma, Z; Peng, L; Song, L; Sun, X; Yang, D; Zheng, Y; Zhu, B | 1 |
| Fitzgerald, ML; Gorzalka, BB; Hill, MN; Hillard, CJ; Karatsoreos, IN; Lee, TT; Liu, QS; Mackie, K; McEwen, BS; McLaughlin, RJ; Pan, B; Pickel, VM; Roberts, CJ; Viau, V | 1 |
| Jakovcevski, M; Morellini, F; Schachner, M | 1 |
| Emelyanov, A; Gong, Z; Koh, CH; Nguyen, AT; Parinov, S; Spitsbergen, JM | 1 |
| Bartlett, SE; Bito-Onon, J; Haass-Koffler, CL; Li, R; Simms, JA | 1 |
| Braun, S; Kottwitz, D; Nuber, UA | 1 |
| Chen, NH; Li, J; Liu, Y; Sun, JD; Yuan, YH | 1 |
| Maggio, N; Segal, M | 1 |
| Chen, MS; He, YH; Huang, Y; Liu, SM; Luo, JD; Luo, MS; Wu, XQ; Zhang, GS; Zhang, HN | 1 |
| Brunnquell, M; Cippitelli, A; Damadzic, R; Eskay, RL; Hamelink, C; Heilig, M; Thorsell, A | 1 |
| Baier, H; Ingraham, HA; Meijsing, SH; Muto, A; Schaaf, MJ; Schoonheim, PJ; Strasser, D; Yamamoto, KR; Ziv, L | 1 |
| Cohen, H; Cohen, S; Kaplan, Z; Kozlovsky, N; Matar, MA; Zohar, J | 1 |
| Bachor, TP; Bermúdez, V; Cubilla, MA; Marquioni Ramella, MD; Suburo, AM | 1 |
| Garcia, EL; Mills, AA | 1 |
| DeMayo, F; Ngan, ES; Schillinger, K; Tsai, SY | 1 |
| Song, C | 1 |
| Lanari, C; Molinolo, AA | 1 |
| Beitz, AJ; Ham, TW; Han, HJ; Kim, HW; Kwon, YB; Lee, JH; Roh, DH; Yang, IS; Yoon, SY | 1 |
| Berki, T; Dran, G; Fernández, GC; Gómez, SA; Isturiz, MA; Palermo, MS; Rubel, C; Vanzulli, S | 1 |
| Avila, AH; Bayer, BM; Morgan, CA | 1 |
| Deng, Y; Liu, Y; Wang, LL | 1 |
| Bruland, T; Dai, HY; Dalen, A; Lavik, LAS | 1 |
| Ishikawa, K; Ohba, T; Okamura, H; Tanaka, N; Ujioka, T | 1 |
| Aouizerate, B; Deroche-Gamonet, V; Ghozland, S; Izawa, R; Jaber, M; Kellendonk, C; Le Moal, M; Piazza, PV; Schütz, G; Sillaber, I; Spanagel, R; Tronche, F | 1 |
| Hsu, CY; Kim, GM; Li, Q; Liu, N; Xu, J; Xu, XM; Yan, P | 1 |
| Chang, KT; Min, KT; Shi, YJ | 1 |
| Parthasarathy, S; Penumetcha, M; Santanam, N; Speisky, H | 1 |
| Jochem, J | 1 |
| Harris, BR; Littleton, JM; Mulholland, PJ; Prendergast, MA; Self, RL | 1 |
| Arbak, S; Gülpinar, MA; Ozbeyli, D; Yeğen, BC | 1 |
| Daly, JM; Duff, M; Freeman, TA; Maddali, S; Smyth, GP; Stapleton, PP; Yan, Z | 1 |
| Barrionuevo, P; Camerano, G; Dran, G; Fernández, GC; Gómez, SA; Isturiz, MA; Palermo, MS; Rosa, FA | 1 |
| Archambault, EZ; Boatright, NK; Fray, J; Hicks, E; Kirchain, S; McCune, SA; Sharkey, LC; Simpson, GI | 1 |
| Akmal, A; Asrat, T; Beharry, K; Chang, E; Gorenberg, D; Nishihara, KC; Waltzman, J | 1 |
| Andersen, ML; Tufik, S | 1 |
| Ahnblad, P; Georén, S; Stierna, P; Stjärne, P; Wikström, AC | 1 |
| Kase, Y; Takeda, S; Takei, H; Yamamoto, M | 1 |
| Haji, A; Ohi, Y; Takeda, R; Yamazaki, H | 1 |
| Bonafé, N; Chambers, SK; Flick, M; Savlu, A; Toy, EP; Zeiss, C; Zheng, W | 1 |
| Chao, PK; Lu, KT; Yang, YL | 1 |
| Kurihara, T; Saegusa, H; Takasaki, I; Tanabe, T; Zong, S | 1 |
| Adamec, R; Blundell, J; Burton, P; McKay, DW; Strasser, K | 1 |
| Bruckdorfer, R; Dooley, A; El-Mahdi, E; Hardiman, P; Lakhani, K; Leonard, A; McLellan, S; Seifalian, A; Sundaresan, M; Yang, W | 1 |
| Bian, Z; Canlon, B; Hansson, AC; Johansson, P; Meltser, I; Stierna, P; Tahera, Y | 1 |
| Fischbach, PS; Rice, KC; Savit, AZ; Verhoeven, RE; Wood, SK; Woods, JH | 1 |
| Benakanakere, I; Besch-Williford, C; Brandt, S; Ellersieck, MR; Hyder, SM; Molinolo, A; Schnell, J | 1 |
| Cao, J; Dong, Z; Han, H; Hao, W; Wang, M; Xu, L | 1 |
| Nishigori, H | 1 |
| Andrade, C; Chandra, JS; Madan Singh, N; Nagaraja, N; Sudha, S; Venkataraman, BV | 1 |
| Chen, L; Da, J; Hedenstierna, G | 1 |
| Adamec, R; Grimes, M; Muir, C; Pearcey, K | 1 |
| Han, H; Hou, HL; Tong, H; Wang, QN; Wu, LM; Yan, XB; Zhou, JN | 1 |
| Harada, K; Hoshino, A; Kato, K; Kato, N; Kohda, K; Matsuoka, N; Morinobu, S; Motohashi, J; Yamaji, T | 1 |
| Berman, BM; Lao, L; Li, A; Ren, K; Tan, M; Wang, Y; Zhang, H; Zhang, RX | 1 |
| Alfarez, DN; Joëls, M; Karst, H; Krugers, HJ; Velzing, EH | 1 |
| de Graaff, M; Dirks, A; Groenink, L; Millan, MJ; Olivier, B; Peeters, BW; Verdouw, PM | 1 |
| Chang, Y; Gu, X; Lim, G; Mao, J; Sung, B; Wang, S; Yang, L; Zeng, Q | 1 |
| Albayrak, A; Borekci, B; Cadirci, E; Halici, Z; Kadanali, S; Suleyman, H | 1 |
| Bryndová, J; Ergang, P; Kment, M; Leden, P; Miksík, I; Pácha, J; Zbánková, S | 1 |
| Hajhashemi, V; Mesripour, A; Rabbani, M | 1 |
| Beitz, AJ; Han, HJ; Kim, HW; Kwon, YB; Lee, HJ; Lee, JH; Roh, DH; Uh, DK; Yoon, SY | 1 |
| Hori, S; Kizu, J; Terajima, T; Tsuchiya, M; Watanabe, S; Yamakami, J | 1 |
| Duda, E; Eder, K; Lázár, G; Paszt, A; Szabolcs, A; Takács, T; Tiszlavicz, L | 1 |
| Barker, JL; Fullerton, CS; Hough, CJ; Li, H; Li, XX; Maric, D; Su, TP; Ursano, R; Webster, MJ; Zhang, L | 1 |
| Clifton, LG; Lin, P; McNulty, JA; Pahel, GL; Shen, Y; Stimpson, SA; Trump, RP; Yang, B | 1 |
| Hughes, SC; Whelan, CJ; Wren, GP | 1 |
| Cohen, Y; Grosset, J; Lazard, T; Perronne, C; Pocidalo, JJ; Truffot-Pernot, C; Vilde, JL | 1 |
| Cech, AC; Daly, JM; Gallagher, H; Shou, J | 1 |
| Capasso, A; Cutrufo, C; Di Giannuario, A; Loizzo, A; Palazzesi, S; Pieretti, S; Sorrentino, L | 1 |
| Pruett, SB; Wu, WJ | 1 |
| Aguilar, R; Gaytán, F; Ruiz, A; Sánchez-Criado, JE; Tébar, AM | 1 |
| Allen, SJ; Baker, D; Bolton, C; O'Neill, JK | 1 |
| Kawano, T; Matsuura, K; Okamura, H; Ujioka, T | 1 |
| Hamada, T; Inoue, M; Ishii, M; Nakanishi, T; Nishi, Y; Sato, EF | 1 |
| Carroll, JL; Pruett, SB; Vinson, RB | 1 |
| Chadwick, CC; Hermsmeyer, K; Minshall, RD; Miyagawa, K; Novy, MJ | 1 |
| Matsuura, K; Okamura, H; Tanaka, N; Ujioka, T | 1 |
| Budel, V; Cahen, P; Chaboteaux, C; Darro, F; Decaestecker, C; Kiss, R; Leblond, B; Nogaret, JM; Pétein, M; Pourrias, B; Ramos, C; Schoofs, A; Vianna, A | 1 |
| Morgan, WW; Richardson, A; Sharp, ZD; Walter, CA | 1 |
| Fraser, T; Li, M; Wen, C; Whitworth, JA | 1 |
| Szukiewicz, D; Uilenbroek, JT | 1 |
| El Etreby, MF; Johnson, MH; Lewis, RW; Liang, Y | 1 |
| Bagger-Sjöbäck, D; Erichsen, S; Hultcrantz, M; Rylander, R; Stierna, P | 1 |
| Clare-Salzler, M; Copeland, EM; Edwards, CK; Fukuzuka, K; Moldawer, LL; Mozingo, DW | 1 |
| Breivik, T; Gjermo, P; Opstad, PK; Thrane, PS | 1 |
| Clare-Salzer, M; Copeland, EM; Edwards, CK; Fukuzuka, K; Moldawer, LL; Mozingo, DW | 1 |
| Ahmed, SH; Hsu, CY; Kim, GM; Xu, J; Xu, XM; Yan, P | 1 |
| Arin, MJ; Longley, MA; Roop, DR; Wang, XJ | 1 |
| Cao, T; Longley, MA; Roop, DR; Wang, XJ | 1 |
| Budziszewska, B; Coenen, A; Ellis, J; Jaworska-Feil, L; Lasoń, W; van Luijtelaar, G | 1 |
| Eaton, MJ; Herman, JP; Huang, J; Jullien, N; Lopez, TL; Martinez, M | 1 |
| DeVries, AC; Hattori, K; Hurn, PD; Morahan, MB; Sugo, N; Traystman, RJ | 1 |
| Cohen, Y; Grosset, J; Perronne, C; Pocidalo, JJ; Truffot-Pernot, C; Vildé, JL | 1 |
| Agarwal, MK; Lazar, G | 1 |
| Bakker, GH; De Jong, FH; Foekens, JA; Klijn, JG; Portengen, H; Setyono-Han, B | 1 |
| Flower, RJ; Moon, D; Peers, SH | 1 |
8 review(s) available for mifepristone and Disease Models, Animal
| Article | Year |
|---|---|
New Insights as to Why Progesterone Receptor Modulators, such as Mifepristone, Seem to Be More Effective in Treating Cancers that Are Devoid of the Classical Nuclear Progesterone Receptor.
Topics: Animals; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Cell Proliferation; Clinical Studies as Topic; Disease Models, Animal; Disease Susceptibility; Drug Discovery; Drug Evaluation, Preclinical; Gene Expression Regulation, Neoplastic; Humans; Membrane Proteins; Mifepristone; Molecular Targeted Therapy; Neoplasms; Prognosis; Receptors, Progesterone; Treatment Outcome | 2021 |
Getting around lethality with inducible Cre-mediated excision.
Topics: Alleles; Anti-Bacterial Agents; Antineoplastic Agents; Base Sequence; Disease Models, Animal; Gene Transfer Techniques; Genetic Techniques; Hormone Antagonists; Integrases; Interferons; Mifepristone; Models, Genetic; Promoter Regions, Genetic; Tamoxifen; Tetracycline; Time Factors; Viral Proteins | 2002 |
The mifepristone-inducible gene regulatory system in mouse models of disease and gene therapy.
Topics: Animals; Disease Models, Animal; Gene Transfer Techniques; Genetic Techniques; Genetic Therapy; Hormone Antagonists; Ligands; Mice; Mifepristone; Models, Genetic; Transgenes | 2002 |
The effect of thymectomy and IL-1 on memory: implications for the relationship between immunity and depression.
Topics: Animals; Corticosterone; Cytokines; Depressive Disorder; Disease Models, Animal; Dopamine; Hormone Antagonists; Interleukin-1; Limbic System; Lymphocytes; Macrophages; Memory Disorders; Mifepristone; Norepinephrine; Rats; Receptors, Glucocorticoid; Serotonin; Thymectomy; Thymus Gland | 2002 |
Progesterone receptors--animal models and cell signalling in breast cancer. Diverse activation pathways for the progesterone receptor: possible implications for breast biology and cancer.
Topics: Animals; Breast; Breast Neoplasms; Disease Models, Animal; Female; Humans; Mifepristone; Progestins; Receptors, Progesterone | 2002 |
[Steroid (glucocorticoid)-induced cataract].
Topics: Animals; Ascorbic Acid; Cataract; Chick Embryo; Disease Models, Animal; Free Radical Scavengers; Glucocorticoids; Glutathione; Insulin; Lipid Peroxides; Liver; Mifepristone; Oxidative Stress; Phosphoprotein Phosphatases; Receptors, Glucocorticoid | 2006 |
Application of exogenously regulatable promoter systems to transgenic models for the study of aging.
Topics: Aging; Animals; Disease Models, Animal; Ecdysone; Embryonic and Fetal Development; Gene Expression Regulation; Growth; Homeostasis; Mice; Mice, Knockout; Mice, Transgenic; Mifepristone; Promoter Regions, Genetic; Tetracycline; Transcription, Genetic; Transcriptional Activation | 1999 |
Polycystic ovary syndrome--searching for an animal model.
Topics: Androgens; Animals; Chorionic Gonadotropin; Dehydroepiandrosterone; Disease Models, Animal; Estradiol; Female; Humans; Insulin; Light; Mifepristone; Polycystic Ovary Syndrome; Rats | 1998 |
182 other study(ies) available for mifepristone and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Investigation of the anti-inflammatory effects of stigmasterol in mice: insight into its mechanism of action.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Inflammation; Male; Mice; Mifepristone; Molecular Docking Simulation; Pain; Peritonitis; Receptors, Glucocorticoid; Stigmasterol | 2021 |
Behavioral and brain morphological analysis of non-inflammatory and inflammatory rat models of preterm brain injury.
Topics: Animals; Brain; Disease Models, Animal; Female; Hippocampus; Hypoxia-Ischemia, Brain; Infant, Premature, Diseases; Male; Mifepristone; Morris Water Maze Test; Open Field Test; Pregnancy; Premature Birth; Rats; Rats, Wistar; Reflex; Spatial Memory | 2021 |
Tamsulosin facilitates depressive-like behaviors in mice: Involvement of endogenous glucocorticoids.
Topics: Adaptation, Psychological; Adrenergic alpha-1 Receptor Antagonists; Aminoglutethimide; Animals; Aromatase Inhibitors; Behavior, Animal; Depression; Disease Models, Animal; Hormone Antagonists; Hypothalamo-Hypophyseal System; Mice; Mifepristone; Receptors, Glucocorticoid; Tamsulosin | 2022 |
The Alterations and Significance of Intercellular Adhesion Molecule-1 in Mouse Brainstem During Herpes Simplex Virus Type 1-Induced Facial Palsy.
Topics: Animals; Bell Palsy; Brain Stem; Disease Models, Animal; Facial Paralysis; Herpesvirus 1, Human; Intercellular Adhesion Molecule-1; Male; Mice; Mice, Inbred BALB C; Mifepristone | 2022 |
Effects of RU486 in Treatment of Traumatic Stress-Induced Glucocorticoid Dysregulation and Fear-Related Abnormalities: Early versus Late Intervention.
Topics: Animals; Corticosterone; Disease Models, Animal; Extinction, Psychological; Fear; Glucocorticoids; Mifepristone; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid | 2022 |
β-sitosterol targets glucocorticoid receptor to reduce airway inflammation and remodeling in allergic asthma.
Topics: Airway Remodeling; Animals; Asthma; Collagen; Disease Models, Animal; Humans; Inflammation; Lung; Mice; Mice, Inbred BALB C; Mifepristone; Molecular Docking Simulation; Ovalbumin; Receptors, Glucocorticoid; Sitosterols; Transforming Growth Factor beta1 | 2023 |
Stress Induces Prolonged Pain Recovery After Surgery: Involvement of Glucocorticoid-Related Pathway.
Topics: Animals; Brain; Disease Models, Animal; Glucocorticoids; Mice; Mifepristone; Pain; Stress, Psychological; Sucrose | 2023 |
Changes in c-fos and p-CREB signaling following exposure to forced swim stress or exogenous corticosterone during morphine-induced place preference are dependent on glucocorticoid receptor in the basolateral amygdala.
Topics: Animals; Basolateral Nuclear Complex; Conditioning, Psychological; Corticosterone; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Humans; Male; Mifepristone; Morphine; Nerve Net; Nucleus Accumbens; Opioid-Related Disorders; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Rats; Receptors, Glucocorticoid; Reward; Signal Transduction; Stereotaxic Techniques; Stress, Psychological | 2020 |
Secretory leukocyte protease inhibitor and progranulin as possible regulators of cervical remodeling in pregnancy.
Topics: Adult; Animals; Cervix Mucus; Cervix Uteri; Disease Models, Animal; Female; Hormone Antagonists; Humans; Lipopolysaccharides; Maternal Age; Mice; Mifepristone; Models, Animal; Pregnancy; Pregnancy Trimester, Second; Premature Birth; Progesterone; Progranulins; Secretory Leukocyte Peptidase Inhibitor; Up-Regulation; Young Adult | 2021 |
Effect of GnRH-antagonist, mifepristone and letrozole on preventing ovarian hyperstimulation syndrome in rat model.
Topics: Animals; Aromatase Inhibitors; Caspase 3; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Gonadotropin-Releasing Hormone; Interleukin-6; Letrozole; Mifepristone; Ovarian Hyperstimulation Syndrome; Ovary; Progesterone; Random Allocation; Rats, Wistar; Vascular Endothelial Growth Factor A | 2021 |
Targeting progesterone signaling prevents metastatic ovarian cancer.
Topics: Adult; Animals; BRCA1 Protein; Breast; Breast Neoplasms; Cystadenocarcinoma, Serous; Disease Models, Animal; Estradiol; Female; Humans; Mice; Middle Aged; Mifepristone; Mutation; Neoplasms, Experimental; Ovarian Neoplasms; Ovary; Progesterone; Receptors, Progesterone; Salpingo-oophorectomy; Signal Transduction | 2020 |
Upsurge in autophagy, associated with mifepristone-treated polycystic ovarian condition, is reversed upon thymoquinone treatment.
Topics: Androgens; Animals; Autophagy; Beclin-1; Benzoquinones; Disease Models, Animal; eIF-2 Kinase; Female; Gene Expression Regulation; Granulosa Cells; Humans; Insulin Resistance; Mifepristone; Ovary; Ovulation; Polycystic Ovary Syndrome; Rats; Receptors, Androgen | 2021 |
Selective progesterone receptor blockade prevents BRCA1-associated mouse mammary tumors through modulation of epithelial and stromal genes.
Topics: Animals; BRCA1 Protein; Breast Neoplasms; Carcinogenesis; Disease Models, Animal; Epithelial Cells; Female; Humans; Mammary Glands, Animal; Mastectomy; Mice; Mifepristone; Norpregnadienes; Receptors, Progesterone; Stromal Cells; Tumor Microenvironment | 2021 |
Glucocorticoids/glucocorticoid receptors effect on dopaminergic neurotransmitters in ADHD rats.
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Corpus Striatum; Dexamethasone; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Glucocorticoids; Male; Mifepristone; Neostriatum; Neurotransmitter Agents; Norepinephrine; Prefrontal Cortex; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Glucocorticoid | 2017 |
Chemical constituents of Cyperus rotundus L. and their inhibitory effects on uterine fibroids.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Biflavonoids; Cyperus; Disease Models, Animal; Estradiol; Female; Flavones; Leiomyoma; Mifepristone; Plant Extracts; Progesterone; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar | 2016 |
Dexamethasone-induced hepatomegaly and steatosis in larval zebrafish.
Topics: Animals; Dexamethasone; Disease Models, Animal; Fatty Liver; Gene Knockdown Techniques; Glucocorticoids; Hepatomegaly; Mifepristone; Receptors, Glucocorticoid; Time Factors; Zebrafish | 2017 |
The effects of cannabinoid receptors activation and glucocorticoid receptors deactivation in the amygdala and hippocampus on the consolidation of a traumatic event.
Topics: Amygdala; Animals; Benzoxazines; Disease Models, Animal; Electroshock; Extinction, Psychological; Fear; Hippocampus; Male; Memory Consolidation; Mental Recall; Mifepristone; Morpholines; Naphthalenes; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptors, Glucocorticoid; Reflex, Startle; Stress Disorders, Post-Traumatic | 2017 |
FKBP5 and specific microRNAs via glucocorticoid receptor in the basolateral amygdala involved in the susceptibility to depressive disorder in early adolescent stressed rats.
Topics: Age Factors; Animals; Basolateral Nuclear Complex; Behavior, Animal; Depressive Disorder; Dexamethasone; Disease Models, Animal; Disease Susceptibility; Glucocorticoids; Hormone Antagonists; Male; Memory Disorders; MicroRNAs; Mifepristone; Rats; Rats, Wistar; Receptors, Glucocorticoid; Stress, Psychological; Tacrolimus Binding Proteins | 2017 |
A novel therapeutic approach for treatment of catamenial epilepsy.
Topics: Animals; Anticonvulsants; CA1 Region, Hippocampal; Disease Models, Animal; Double-Blind Method; Epilepsy; Estrous Cycle; Female; Gene Expression; Menstrual Cycle; Mice, Inbred C57BL; Mice, Knockout; Mifepristone; Neurons; Progesterone; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Progesterone; RNA, Messenger; Synaptic Transmission | 2018 |
Juvenile social defeat stress exposure persistently impairs social behaviors and neurogenesis.
Topics: Age Factors; Analysis of Variance; Animals; Bromodeoxyuridine; Disease Models, Animal; Exploratory Behavior; Food Preferences; Hormone Antagonists; Interpersonal Relations; Ki-67 Antigen; Locomotion; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mifepristone; Neurogenesis; Stress, Psychological; Swimming | 2018 |
Targeting glucocorticoid receptors prevents the effects of early life stress on amyloid pathology and cognitive performance in APP/PS1 mice.
Topics: Age Factors; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Behavior, Animal; Cognitive Dysfunction; Corticosterone; Disease Models, Animal; Female; Hippocampus; Hormone Antagonists; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mifepristone; Peptide Fragments; Receptors, Glucocorticoid; Stress, Psychological | 2018 |
Mifepristone attenuates depression-like changes induced by chronic central administration of interleukin-1β in rats.
Topics: Amygdala; Anhedonia; Animals; Antidepressive Agents; Corticosterone; Depressive Disorder; Disease Models, Animal; Hormone Antagonists; Interleukin-1beta; Male; Mifepristone; Motor Activity; Nerve Growth Factors; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Recombinant Proteins; RNA, Messenger | 2018 |
Impaired CD8 T cell antiviral immunity following acute spinal cord injury.
Topics: Acute Disease; Animals; Antiviral Agents; Body Weight; CD8-Positive T-Lymphocytes; Cells, Cultured; Cytokines; Disease Models, Animal; Female; Flow Cytometry; Hemagglutinin Glycoproteins, Influenza Virus; Hormone Antagonists; Inflammation; Lung; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mifepristone; Orthomyxoviridae Infections; Spinal Cord Injuries; Spleen | 2018 |
Therapeutic efficacy of regulable GDNF expression for Huntington's and Parkinson's disease by a high-induction, background-free "GeneSwitch" vector.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Disease Models, Animal; Gene Expression Regulation; Glial Cell Line-Derived Neurotrophic Factor; Green Fluorescent Proteins; Homovanillic Acid; Hormone Antagonists; Huntingtin Protein; Huntington Disease; Mice; Mice, Transgenic; Mifepristone; Oxidopamine; Parkinson Disease; Synapsins; Synucleins; Transduction, Genetic | 2018 |
Mifepristone alleviates cerebral ischemia-reperfusion injury in rats by stimulating PPAR γ.
Topics: Animals; Brain; Cytokines; Cytoprotection; Disease Models, Animal; Infarction, Middle Cerebral Artery; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mifepristone; Neurons; Neuroprotective Agents; PPAR gamma; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Tissue Inhibitor of Metalloproteinase-1 | 2018 |
Protective role of GPR120 in the maintenance of pregnancy by promoting decidualization via regulation of glucose metabolism.
Topics: Abortion, Spontaneous; Adult; Animals; Cell Line; Decidua; Disease Models, Animal; Down-Regulation; Fatty Acids, Omega-3; Female; Glucose; Humans; Lipopolysaccharides; Mice; Mifepristone; Pentose Phosphate Pathway; Pregnancy; Receptors, G-Protein-Coupled; Stromal Cells | 2019 |
Late glucocorticoid receptor antagonism changes the outcome of adult life stress.
Topics: Animals; Brain; Corticosterone; Disease Models, Animal; Exploratory Behavior; Extinction, Psychological; Fear; Hippocampus; Male; Mifepristone; Rats; Rats, Wistar; Receptors, Glucocorticoid; Stress, Psychological | 2019 |
Glucocorticoid-induced hypertension and cardiac injury: effects of mineralocorticoid and glucocorticoid receptor antagonism.
Topics: Animals; Atrophy; Blood Pressure; Corticosterone; Disease Models, Animal; Fibrosis; Heart Diseases; Hypertension; Inflammation Mediators; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone; Time Factors; Ventricular Dysfunction, Left; Ventricular Function, Left | 2013 |
Genomic and non-genomic effects of glucocorticoids on allergic rhinitis model in mice.
Topics: Adenosine Triphosphate; Animals; Behavior, Animal; Cinnamates; Disease Models, Animal; Estrenes; Female; Genomics; Glucocorticoids; Histamine; Hormone Antagonists; Mice; Mice, Inbred ICR; Mifepristone; Mometasone Furoate; ortho-Aminobenzoates; Phospholipase A2 Inhibitors; Pregnadienediols; Pyrrolidinones; Receptors, Glucocorticoid; Rhinitis, Allergic; Rhinitis, Allergic, Perennial; Sneezing; Substance P; Type C Phospholipases | 2013 |
Autonomic dysreflexia causes chronic immune suppression after spinal cord injury.
Topics: Adrenergic beta-2 Receptor Antagonists; Animals; Antigens, CD; Autonomic Dysreflexia; Blood Pressure; Butoxamine; Colon; Corticosterone; Disease Models, Animal; Epinephrine; Female; Hormone Antagonists; Humans; Immune System Diseases; Immunosuppression Therapy; Mice; Mifepristone; Norepinephrine; Ovalbumin; Physical Stimulation; Spinal Cord Injuries; T-Lymphocytes; Telemetry | 2013 |
Mifepristone promotes adiponectin production and improves insulin sensitivity in a mouse model of diet-induced-obesity.
Topics: 3T3-L1 Cells; Adiponectin; Adipose Tissue; Animals; Cell Differentiation; Diet, High-Fat; Disease Models, Animal; Insulin Resistance; Male; Mice; Mifepristone; Obesity | 2013 |
Pharmacologically controlled, discontinuous GDNF gene therapy restores motor function in a rat model of Parkinson's disease.
Topics: Adenoviridae; Analysis of Variance; Animals; Disease Models, Animal; Dopamine; Functional Laterality; Genetic Therapy; Genetic Vectors; Glial Cell Line-Derived Neurotrophic Factor; Glial Fibrillary Acidic Protein; Hormone Antagonists; Mifepristone; Motor Activity; Oxidopamine; Parkinson Disease; Rats; Rotation; Sympatholytics; Time Factors; Vesicular Monoamine Transport Proteins | 2014 |
Dexamethasone decreases insulin-like growth factor-I and -II via a glucocorticoid receptor dependent mechanism in developing rat brain.
Topics: Animals; Animals, Newborn; Brain; Brain-Derived Neurotrophic Factor; Dexamethasone; Disease Models, Animal; Drug Interactions; Female; Glucocorticoids; Hormone Antagonists; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Mifepristone; Nerve Growth Factor; Neurodegenerative Diseases; Organ Size; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid | 2013 |
Forced swim stress but not exogenous corticosterone could induce the reinstatement of extinguished morphine conditioned place preference in rats: involvement of glucocorticoid receptors in the basolateral amygdala.
Topics: Amygdala; Analysis of Variance; Animals; Conditioning, Operant; Corticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Extinction, Psychological; Hormone Antagonists; Male; Mifepristone; Morphine; Narcotics; Rats; Rats, Wistar; Receptors, Glucocorticoid; Stress, Psychological; Swimming | 2014 |
Changes in intestinal glucocorticoid sensitivity in early life shape the risk of epithelial barrier defect in maternal-deprived rats.
Topics: Analysis of Variance; Animals; Azepines; Bacterial Translocation; Colon; Colony-Forming Units Assay; Corticosterone; Dexamethasone; Dextrans; Disease Models, Animal; DNA Primers; Dose-Response Relationship, Drug; Female; Fluorescein-5-isothiocyanate; Glucocorticoids; Humans; Infant, Premature; Intestinal Mucosa; Male; Maternal Deprivation; Mifepristone; Naphthalenes; Permeability; Rats; Real-Time Polymerase Chain Reaction; Receptors, Glucocorticoid | 2014 |
Glucocorticoid-mediated enhancement of glutamatergic transmission may outweigh anti-inflammatory effects under conditions of neuropathic pain.
Topics: Animals; Anti-Inflammatory Agents; Body Weight; Cytokines; Disease Models, Animal; Gene Expression; Glucocorticoids; Glutamic Acid; Male; Mifepristone; Neuralgia; Pain Threshold; Peripheral Nerve Injuries; Rats; Receptors, Glucocorticoid; Synaptic Transmission | 2014 |
The involvement of glucocorticoids in psychological stress-induced exacerbations of experimental allergic asthma.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Corticosterone; Disease Models, Animal; Female; Glucocorticoids; Inflammation; Interleukin-12; Interleukin-13; Male; Mice; Mice, Inbred BALB C; Mifepristone; Receptors, Glucocorticoid; Respiratory System; Sex Factors; Stress, Psychological; T-Lymphocytes, Regulatory; Th2 Cells | 2014 |
Lifetime-dependent effects of bisphenol A on asthma development in an experimental mouse model.
Topics: Animals; Asthma; Benzhydryl Compounds; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking Water; Endocrine Disruptors; Female; Mice; Mice, Inbred BALB C; Mifepristone; Ovalbumin; Phenols; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, Glucocorticoid; Time Factors | 2014 |
Mind the gap: glucocorticoids modulate hippocampal glutamate tone underlying individual differences in stress susceptibility.
Topics: Animals; Disease Models, Animal; Disease Susceptibility; Food Preferences; Glucocorticoids; Glutamic Acid; Hippocampus; Immobility Response, Tonic; Individuality; Mice; Mice, Inbred C57BL; Mice, Knockout; Mifepristone; Receptors, Metabotropic Glutamate; Receptors, Mineralocorticoid; Stress, Psychological; Sucrose; Sweetening Agents | 2015 |
α-ENaC, a therapeutic target of dexamethasone on hydrogen sulfide induced acute pulmonary edema.
Topics: Animals; Cell Line; Dexamethasone; Disease Models, Animal; Epithelial Sodium Channels; Gene Expression Regulation; Hydrogen Sulfide; Lung; Male; Mifepristone; Protective Agents; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Signal Transduction | 2014 |
Activation of NF-κB signaling pathway in HSV-1-induced mouse facial palsy: Possible relation to therapeutic effect of glucocorticoids.
Topics: Active Transport, Cell Nucleus; Animals; Anti-Inflammatory Agents; Brain Stem; Cyclooxygenase 2; Disease Models, Animal; Facial Paralysis; Glucocorticoids; Herpesvirus 1, Human; Hormone Antagonists; I-kappa B Kinase; Male; Methylprednisolone Hemisuccinate; Mice, Inbred BALB C; Mifepristone; NF-kappa B; Pyrrolidines; Receptors, Glucocorticoid; Signal Transduction; Thiocarbamates; Tumor Necrosis Factor-alpha | 2015 |
Subchronic glucocorticoid receptor inhibition rescues early episodic memory and synaptic plasticity deficits in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Dexamethasone; Disease Models, Animal; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glucocorticoids; Hippocampus; Hormone Antagonists; Humans; Memory Disorders; Memory, Episodic; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mifepristone; Mutation; Neuronal Plasticity; Quinoxalines; Receptors, Glucocorticoid; Recognition, Psychology; Valine | 2015 |
Prior chronic stress induces persistent polyI:C-induced allodynia and depressive-like behavior in rats: Possible involvement of glucocorticoids and microglia.
Topics: Animals; Body Weight; Depression; Disease Models, Animal; Drug Administration Routes; Eating; Fever; Hormone Antagonists; Hyperalgesia; Interferon Inducers; Male; Mifepristone; Minocycline; Pain Management; Poly I-C; Rats; Rats, Long-Evans; Rats, Wistar; Stress, Psychological; Swimming; Time Factors | 2015 |
Blockade of glucocorticoid receptors with RU486 attenuates cardiac damage and adipose tissue inflammation in a rat model of metabolic syndrome.
Topics: Adipocytes; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Gene Expression; Heart; Heart Diseases; Hormone Antagonists; Male; Metabolic Syndrome; Mifepristone; Panniculitis; Rats; Receptors, Glucocorticoid; Renin-Angiotensin System | 2015 |
Effects of early-life stress on cognitive function and hippocampal structure in female rodents.
Topics: Animals; Animals, Newborn; Anxiety; Cognition; Disease Models, Animal; Female; Gambling; Hippocampus; Hormone Antagonists; Maternal Deprivation; Memory; Mifepristone; Neurogenesis; Neurons; Random Allocation; Rats, Wistar; Receptors, Glucocorticoid; Sexual Maturation; Stress, Psychological; Treatment Failure | 2017 |
Short-Term Sleep Disturbance-Induced Stress Does not Affect Basal Pain Perception, but Does Delay Postsurgical Pain Recovery.
Topics: Animals; Chronic Disease; Corticosterone; Disease Models, Animal; Disease Progression; Female; Ganglia, Spinal; Hormone Antagonists; Kv1.2 Potassium Channel; Lumbar Vertebrae; Male; Mifepristone; Pain Perception; Pain, Postoperative; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sleep Wake Disorders; Sleep, REM; Spinal Cord; Stress, Physiological | 2015 |
Application of a Patient Derived Xenograft Model for Predicative Study of Uterine Fibroid Disease.
Topics: Animals; Disease Models, Animal; Estrogen Receptor alpha; Estrogens; Female; Heterografts; Humans; Leiomyoma; Mice; Mice, SCID; Mifepristone; Receptors, Progesterone | 2015 |
Treadmill exercise ameliorates ischemia-induced brain edema while suppressing Na⁺/H⁺ exchanger 1 expression.
Topics: Acid Sensing Ion Channel Blockers; Animals; Aquaporin 4; Brain Edema; Cells, Cultured; Corticosterone; Cytokines; Disease Models, Animal; Exercise Therapy; Functional Laterality; Gene Expression Regulation; Infarction, Middle Cerebral Artery; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Nerve Tissue Proteins; Neuroglia; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Spironolactone; Time Factors | 2016 |
A novel combined glucocorticoid-mineralocorticoid receptor selective modulator markedly prevents weight gain and fat mass expansion in mice fed a high-fat diet.
Topics: Adipose Tissue; Animals; Diet, High-Fat; Disease Models, Animal; Female; Male; Mice; Mice, Inbred C57BL; Mifepristone; Mineralocorticoid Receptor Antagonists; Receptors, Glucocorticoid; Thymine; Weight Gain | 2016 |
Increase of kisspeptin-positive cells in the hypothalamus of a rat model of polycystic ovary syndrome.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Disease Models, Animal; Estradiol; Female; Follicle Stimulating Hormone; Kisspeptins; Luteinizing Hormone; Mifepristone; Neurons; Polycystic Ovary Syndrome; Progesterone; Rats; Testosterone | 2016 |
In vitro and in vivo efficacy and safety evaluation of metapristone and mifepristone as cancer metastatic chemopreventive agents.
Topics: Animals; Anticarcinogenic Agents; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chemoprevention; Disease Models, Animal; Female; Integrin alpha4; Liver; Lung Neoplasms; Melanoma, Experimental; Mice, Inbred C57BL; Mifepristone; Treatment Outcome | 2016 |
Mifepristone Suppresses Basal Triple-Negative Breast Cancer Stem Cells by Down-regulating KLF5 Expression.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Disease Models, Animal; Gene Expression; Heterografts; Humans; Kruppel-Like Transcription Factors; Mice, Inbred NOD; Mice, SCID; MicroRNAs; Mifepristone; Stem Cells; Treatment Outcome; Triple Negative Breast Neoplasms | 2016 |
Increased glycogen synthase kinase-3β and hexose-6-phosphate dehydrogenase expression in adipose tissue may contribute to glucocorticoid-induced mouse visceral adiposity.
Topics: Adipocytes; Adipogenesis; Adipose Tissue; Adiposity; Animals; Carbohydrate Dehydrogenases; Disease Models, Animal; Glucocorticoids; Glycogen Synthase Kinase 3 beta; Hormone Antagonists; Intra-Abdominal Fat; Male; Mice; Mice, Inbred C57BL; Mifepristone; Obesity, Abdominal; Receptors, Glucocorticoid | 2016 |
Attenuation of cold stress-induced exacerbation of cardiac and adipose tissue pathology and metabolic disorders in a rat model of metabolic syndrome by the glucocorticoid receptor antagonist RU486.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipose Tissue; Animals; Cold Temperature; Disease Models, Animal; Fibrosis; Glucose Intolerance; Heart; Hypertrophy, Left Ventricular; Male; Metabolic Syndrome; Mifepristone; Rats; Rats, Inbred Dahl; Rats, Zucker; Receptors, Glucocorticoid; Receptors, Leptin; Stress, Physiological | 2016 |
Glucocorticoid receptor mediated the propofol self-administration by dopamine D1 receptor in nucleus accumbens.
Topics: Aldosterone; Animals; Corticosterone; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Glucocorticoids; Hormone Antagonists; Hypnotics and Sedatives; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Motor Activity; Nucleus Accumbens; Propofol; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Self Administration; Substance-Related Disorders | 2016 |
A novel role for the mineralocorticoid receptor in glucocorticoid driven vascular calcification.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Apoptosis; Corticosterone; Disease Models, Animal; Eplerenone; Flow Cytometry; Glucocorticoids; Mice; Mice, Inbred C57BL; Mifepristone; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphates; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; RNA, Messenger; Spironolactone; Vascular Calcification | 2016 |
Diurnal Variation of the Peripheral Cholinergic Antiinflammatory Function in Mice.
Topics: Acetylcholine; Aconitine; Animals; Circadian Rhythm; Corticosterone; Cytokines; Disease Models, Animal; Hormone Antagonists; Inflammation; Kidney; Lipopolysaccharides; Liver; Mice; Mice, Inbred C57BL; Mifepristone; Nicotinic Antagonists; Vesicular Acetylcholine Transport Proteins | 2016 |
Amyloid-β induces sleep fragmentation that is rescued by fatty acid binding proteins in Drosophila.
Topics: Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Disease Models, Animal; Drosophila; Drosophila Proteins; Fatty Acid-Binding Proteins; Gene Expression Regulation; Hormone Antagonists; Humans; Locomotion; Mifepristone; RNA, Messenger; Sleep; Sleep Wake Disorders; Transcription Factors; Wakefulness | 2017 |
Influence of Adrenalectomy on Protective Effects of Urocortin I, a Corticotropin-Releasing Factor, Against Indomethacin-Induced Enteropathy in Rats.
Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Dose-Response Relationship, Drug; Enterobacteriaceae; Gastrointestinal Agents; Gastrointestinal Motility; Hormone Antagonists; Indomethacin; Intestinal Diseases; Intestine, Small; Male; Mifepristone; Nitric Oxide Synthase Type II; Peroxidase; Rats, Sprague-Dawley; Urocortins | 2016 |
New selective glucocorticoid receptor modulators reverse amyloid-β peptide-induced hippocampus toxicity.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Aza Compounds; Cognitive Dysfunction; Disease Models, Animal; Dose-Response Relationship, Drug; Glucocorticoids; Heterocyclic Compounds, 4 or More Rings; Hippocampus; Hypothalamo-Hypophyseal System; Isoquinolines; Male; Mifepristone; Molecular Targeted Therapy; Pituitary-Adrenal System; Pyrazoles; Rats, Sprague-Dawley; Receptors, Glucocorticoid | 2016 |
Maternal Separation Induces Orofacial Mechanical Allodynia in Adulthood.
Topics: Adrenal Cortex Hormones; Animals; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Facial Pain; Female; Hyperalgesia; Male; Maternal Deprivation; Mifepristone; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X3; Trigeminal Ganglion; Vibrissae | 2016 |
Requisite Role of Basolateral Amygdala Glucocorticoid Receptor Stimulation in Drug Context-Induced Cocaine-Seeking Behavior.
Topics: Animals; Basolateral Nuclear Complex; Behavior, Animal; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Hormone Antagonists; Male; Mifepristone; Motivation; Motor Activity; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Recurrence; Reinforcement Schedule; Signal Transduction; Time Factors | 2016 |
Corticosteroids Mediate Heart Failure-Induced Depression through Reduced σ1-Receptor Expression.
Topics: Adenosine Triphosphate; Administration, Oral; Animals; Aorta; Behavior, Animal; Cardiomegaly; Corticosterone; Dentate Gyrus; Depression; Disease Models, Animal; Down-Regulation; Echocardiography; Heart Failure; Hippocampus; Male; Mice; Mice, Inbred ICR; Mifepristone; Piperazines; Receptors, sigma | 2016 |
Anti-proliferative and anti-inflammatory effects of 3β,6β,16β-Trihydroxylup-20(29)-ene on cutaneous inflammation.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Cell Line; Cell Proliferation; Chronic Disease; Dermatitis, Contact; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Female; Hormone Antagonists; Humans; Keratinocytes; Mice; Mifepristone; Proliferating Cell Nuclear Antigen; Psoriasis; Receptors, Glucocorticoid; Skin; Tetradecanoylphorbol Acetate; Time Factors; Triterpenes | 2017 |
Dexamethasone-induced diuresis is associated with inhibition of the renin-angiotensin-aldosterone system in rats.
Topics: Animals; Chronic Disease; Dehydration; Dexamethasone; Disease Models, Animal; Diuresis; Heart Failure; Male; Mifepristone; Rats, Sprague-Dawley; Renin-Angiotensin System; Time Factors | 2016 |
Glucocorticoid receptor promotes the function of myeloid-derived suppressor cells by suppressing HIF1α-dependent glycolysis.
Topics: Animals; Dexamethasone; Disease Models, Animal; Down-Regulation; Glycolysis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immune Tolerance; Immunity, Innate; Inflammation; Lipopolysaccharides; Liver; Mice, Inbred C57BL; Mifepristone; Myeloid-Derived Suppressor Cells; Receptors, Glucocorticoid; Signal Transduction | 2018 |
Stress induces a switch of intracellular signaling in sensory neurons in a model of generalized pain.
Topics: Adrenalectomy; Analysis of Variance; Animals; Behavior, Animal; Corticosterone; Dinoprostone; Disease Models, Animal; Epinephrine; Hormone Antagonists; Hyperalgesia; Male; Mifepristone; Muscle, Skeletal; Neurons, Afferent; Pain; Pain Threshold; Rats; Rats, Sprague-Dawley; Signal Transduction; Skin; Sound; Stress, Physiological; Time Factors | 2008 |
Two different molecular mechanisms underlying progesterone neuroprotection against ischemic brain damage.
Topics: Animals; Behavior, Animal; Calcium; Cell Death; Disease Models, Animal; Hippocampus; Hormone Antagonists; Infarction, Middle Cerebral Artery; Male; Maze Learning; Memory; Mifepristone; Mitogen-Activated Protein Kinase 3; N-Methylaspartate; Neurofilament Proteins; Neuroprotective Agents; Progesterone; Protein Transport; Rats; Rats, Sprague-Dawley; Signal Transduction; Space Perception; Time Factors | 2008 |
Suppressive effects of nitric oxide-releasing prednisolone NCX-1015 on the allergic pleural eosinophil recruitment in rats.
Topics: Animals; Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Chemokine CCL11; Cysteine; Disease Models, Animal; Drug Therapy, Combination; Eosinophilia; Eosinophils; Hypersensitivity; Leukocytes; Leukocytes, Mononuclear; Leukotrienes; Male; Mifepristone; Neutrophils; Nitric Oxide Donors; Nitroso Compounds; Ovalbumin; Pleural Cavity; Pleurisy; Prednisolone; Rats; Rats, Wistar; Receptors, Glucocorticoid | 2008 |
[Influence of mifepristone on DNA repair genes and cisplatin sensitivity in human ovarian cancer drug-resistance cells].
Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents; Apoptosis; BRCA1 Protein; Cell Cycle; Cell Line, Tumor; Cisplatin; Disease Models, Animal; DNA Damage; DNA Repair; DNA-Binding Proteins; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Endonucleases; Female; Humans; Mice; Mice, Nude; Mifepristone; MutL Protein Homolog 1; Neoplasm Transplantation; Nuclear Proteins; Ovarian Neoplasms; RNA, Messenger | 2008 |
Support for the hypothesis that successful immunotherapy of various cancers can be achieved by inhibiting a progesterone associated immunomodulatory protein.
Topics: Animals; Disease Models, Animal; Humans; Immunologic Factors; Immunotherapy; Lung Neoplasms; Mice; Mifepristone; Neoplasms; Pregnancy Proteins; Progesterone; Receptors, Progesterone; RNA, Messenger; Suppressor Factors, Immunologic | 2009 |
The molecular mechanism of dexamethasone-mediated effect on the blood-brain tumor barrier permeability in a rat brain tumor model.
Topics: Animals; Anti-Inflammatory Agents; Blood-Brain Barrier; Brain Edema; Brain Neoplasms; Cerebral Arteries; Dexamethasone; Disease Models, Animal; Endothelial Cells; Evans Blue; Female; Indicators and Reagents; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Membrane Proteins; Mifepristone; Occludin; Rats; Rats, Wistar; Receptors, Glucocorticoid | 2009 |
Chronic blockade of hindbrain glucocorticoid receptors reduces blood pressure responses to novel stress and attenuates adaptation to repeated stress.
Topics: Adaptation, Physiological; Animals; Blood Pressure; Body Weight; Corticosterone; Disease Models, Animal; Heart Rate; Hormone Antagonists; Hypertension; Male; Mifepristone; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Rhombencephalon; Stress, Physiological | 2009 |
Glucocorticoid receptor and mitogen-activated protein kinase activity after restraint stress and acoustic trauma.
Topics: Animals; Cochlea; Cochlear Nerve; Corticosterone; Disease Models, Animal; Down-Regulation; Hearing Loss, Noise-Induced; Hormone Antagonists; Male; MAP Kinase Signaling System; Mice; Mice, Inbred CBA; Mifepristone; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Pyridines; Receptors, Glucocorticoid; Restraint, Physical; Sensory Receptor Cells; Spiral Ganglion; Stress, Psychological | 2009 |
Relevance of an opioid, noscapine in reducing cystogeneses in rat experimental model of polycystic ovary syndrome.
Topics: Analgesics, Opioid; Androgen Antagonists; Animals; Cysts; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Estradiol; Estrous Cycle; Female; Flutamide; Follicle Stimulating Hormone; Hormone Antagonists; Luteinizing Hormone; Mifepristone; Noscapine; Organ Size; Ovary; Ovulation; Polycystic Ovary Syndrome; Prolactin; Rats; Rats, Wistar; Testosterone; Uterus | 2009 |
Mineralocorticoid and glucocorticoid receptors stimulate epithelial sodium channel activity in a mouse model of Cushing syndrome.
Topics: Adrenocorticotropic Hormone; Animals; Blood Pressure; Cushing Syndrome; Disease Models, Animal; Epithelial Sodium Channels; Glomerular Filtration Rate; Hormone Antagonists; Loop of Henle; Male; Mice; Mice, Inbred C57BL; Mifepristone; Mineralocorticoid Receptor Antagonists; Receptors, Adrenergic, alpha-1; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Receptors, Vasopressin; Sodium; Sodium-Potassium-Chloride Symporters; Spironolactone | 2009 |
Preterm and term cervical ripening in CD1 Mice (Mus musculus): similar or divergent molecular mechanisms?
Topics: Analysis of Variance; Animals; Cervical Ripening; Cervix Uteri; Cytokines; Databases, Genetic; Desmoglein 1; Disease Models, Animal; Female; Gestational Age; Immunohistochemistry; Inflammation; Lipopolysaccharides; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mifepristone; Oligonucleotide Array Sequence Analysis; Pregnancy; Premature Birth; Principal Component Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Tissue Inhibitor of Metalloproteinase-2 | 2009 |
Enhanced expression of P2X4 and P2X7 purinergic receptors in the myometrium of pregnant rats in preterm delivery models.
Topics: Animals; Blotting, Western; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Female; Gestational Age; Lipopolysaccharides; Mifepristone; Myometrium; Pregnancy; Premature Birth; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2X4; Receptors, Purinergic P2X7; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation | 2009 |
Involvement of connexin 43 in the acupuncture effect of improving rat blastocyst implantation.
Topics: Acupuncture Therapy; Animals; Blastocyst; Connexin 43; Disease Models, Animal; Embryo Implantation; Embryo Implantation, Delayed; Female; Infertility, Female; Mifepristone; Pregnancy; Pregnancy Rate; Rats; Rats, Wistar; RNA Interference; RNA, Messenger | 2010 |
Reductions of acetylcholine release and nerve growth factor expression are correlated with memory impairment induced by interleukin-1beta administrations: effects of omega-3 fatty acid EPA treatment.
Topics: Acetylcholine; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Disease Models, Animal; Drug Administration Schedule; Eicosapentaenoic Acid; Electrochemical Techniques; Gene Expression Regulation; Hippocampus; Hormone Antagonists; Interleukin-1beta; Male; Memory Disorders; Microdialysis; Mifepristone; Nerve Growth Factor; Rats; Rats, Long-Evans; Statistics as Topic; Time Factors | 2010 |
CRF-1 antagonist and CRF-2 agonist decrease binge-like ethanol drinking in C57BL/6J mice independent of the HPA axis.
Topics: Alcohol-Induced Disorders, Nervous System; Animals; Corticotropin-Releasing Hormone; Disease Models, Animal; Hormone Antagonists; Hypothalamo-Hypophyseal System; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mice; Mice, Inbred C57BL; Mifepristone; Peptide Fragments; Pyridines; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Signal Transduction; Urocortins | 2010 |
A novel mifepristone-loaded implant for long-term treatment of endometriosis: in vitro and in vivo studies.
Topics: Animals; Disease Models, Animal; Drug Implants; Endometriosis; Female; Hormone Antagonists; In Vitro Techniques; Microscopy, Electron, Scanning; Mifepristone; Molecular Weight; Rats; Rats, Wistar; Spectroscopy, Fourier Transform Infrared | 2010 |
Inflammation-induced preterm birth alters neuronal morphology in the mouse fetal brain.
Topics: Amniotic Fluid; Animals; Brain; Cell Survival; Cells, Cultured; Cytokines; Disease Models, Animal; Female; Inflammation Mediators; Lipopolysaccharides; Mice; Mifepristone; Neurons; Pregnancy; Pregnancy Complications, Infectious; Premature Birth; RNA, Messenger | 2010 |
Stress within the postseizure time window inhibits seizure recurrence.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Anticonvulsants; Circadian Rhythm; Corticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Hormone Antagonists; Kindling, Neurologic; Mifepristone; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Secondary Prevention; Seizures; Spironolactone; Stress, Physiological; Time Factors | 2010 |
Sepsis and glucocorticoids upregulate p300 and downregulate HDAC6 expression and activity in skeletal muscle.
Topics: Animals; Dexamethasone; Disease Models, Animal; Down-Regulation; E1A-Associated p300 Protein; Gene Expression Regulation, Enzymologic; Glucocorticoids; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Histone Deacetylases; Hormone Antagonists; Hydroxamic Acids; Male; Mifepristone; Muscle Proteins; Muscle, Skeletal; Muscular Atrophy; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; RNA, Messenger; Sepsis; Sirtuin 1; SKP Cullin F-Box Protein Ligases; Time Factors; Tripartite Motif Proteins; Ubiquitin-Protein Ligases; Up-Regulation | 2010 |
Foetal hypoxia increases cardiac AT(2)R expression and subsequent vulnerability to adult ischaemic injury.
Topics: Age Factors; Angiotensin II Type 2 Receptor Blockers; Animals; Binding Sites; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fetal Hypoxia; Gestational Age; Glucocorticoids; Hormone Antagonists; Imidazoles; Male; Mifepristone; Myocardial Reperfusion Injury; Myocardium; Organ Culture Techniques; Pregnancy; Promoter Regions, Genetic; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Glucocorticoid; RNA, Messenger; Up-Regulation; Ventricular Function, Left; Ventricular Pressure | 2011 |
Corticosterone mediates reciprocal changes in CB 1 and TRPV1 receptors in primary sensory neurons in the chronically stressed rat.
Topics: Animals; Benzoxazines; Chronic Disease; Colon; Corticosterone; Disease Models, Animal; Feces; Ganglia, Spinal; Hyperalgesia; Male; Mifepristone; Morpholines; Naphthalenes; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptors, Glucocorticoid; Sensory Receptor Cells; Stress, Psychological; TRPV Cation Channels | 2011 |
Brain aging and Aβ₁₋₄₂ neurotoxicity converge via deterioration in autophagy-lysosomal system: a conditional Drosophila model linking Alzheimer's neurodegeneration with aging.
Topics: Age Factors; Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Autophagy; Brain; Disease Models, Animal; Drosophila; Drosophila Proteins; Gene Expression Regulation; Green Fluorescent Proteins; Hormone Antagonists; Humans; Lysosomes; Microscopy, Confocal; Microscopy, Electron, Transmission; Mifepristone; Neurons; Peptide Fragments | 2011 |
Progesterone receptor antagonist CDB-4124 increases depression-like behavior in mice without affecting locomotor ability.
Topics: Animals; Depression; Depression, Postpartum; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Finasteride; Locomotion; Mice; Mice, Inbred DBA; Mifepristone; Norpregnadienes; Premenstrual Syndrome; Progesterone; Receptors, Progesterone; Single-Blind Method; Swimming | 2011 |
Mifepristone inhibits MPA-and FGF2-induced mammary tumor growth but not FGF2-induced mammary hyperplasia.
Topics: Animals; Disease Models, Animal; Female; Fibroblast Growth Factor 2; Hormone Antagonists; Hyperplasia; Mammary Glands, Animal; Mammary Neoplasms, Animal; Medroxyprogesterone Acetate; Mice; Mifepristone | 2010 |
Chronic potassium depletion increases adrenal progesterone production that is necessary for efficient renal retention of potassium.
Topics: Adrenal Glands; Aldosterone; Analysis of Variance; Animals; Cell Line; Chronic Disease; Corticosterone; Disease Models, Animal; Female; Gene Expression Regulation, Enzymologic; H(+)-K(+)-Exchanging ATPase; Hormone Antagonists; Humans; Hypokalemia; Kidney; Male; Mice; Mice, Knockout; Mifepristone; Models, Biological; Potassium, Dietary; Progesterone; Receptors, Progesterone; Sodium, Dietary; Time Factors; Up-Regulation | 2011 |
The respective and interaction effects of spinal GRs and MRs on radicular pain induced by chronic compression of the dorsal root ganglion in the rat.
Topics: Animals; Dexamethasone; Disease Models, Animal; Drug Synergism; Ganglia, Spinal; Hormone Antagonists; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Radiculopathy; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 2011 |
Recruitment of prefrontal cortical endocannabinoid signaling by glucocorticoids contributes to termination of the stress response.
Topics: Animals; Arachidonic Acids; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Corticosterone; Disease Models, Animal; Electric Stimulation; Endocannabinoids; Freezing Reaction, Cataleptic; gamma-Aminobutyric Acid; Glycerides; Hormone Antagonists; In Vitro Techniques; Long-Term Synaptic Depression; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Microscopy, Electron, Transmission; Mifepristone; Patch-Clamp Techniques; Piperidines; Prefrontal Cortex; Pyramidal Cells; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Signal Transduction; Stress, Psychological | 2011 |
Susceptibility to the long-term anxiogenic effects of an acute stressor is mediated by the activation of the glucocorticoid receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Anti-Anxiety Agents; Cocaine; Conditioning, Operant; Corticotropin-Releasing Hormone; Diazepam; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Gene Expression Regulation; Hormone Antagonists; Hypothalamus; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mifepristone; Proto-Oncogene Proteins c-fos; Radioimmunoassay; Rats; Receptors, Glucocorticoid; RNA, Messenger; Serotonin Receptor Agonists; Stress, Psychological; Time Factors; Tyrosine 3-Monooxygenase | 2011 |
An inducible kras(V12) transgenic zebrafish model for liver tumorigenesis and chemical drug screening.
Topics: Animals; Animals, Genetically Modified; Cell Transformation, Neoplastic; Disease Models, Animal; Disease Progression; Drug Screening Assays, Antitumor; Extracellular Signal-Regulated MAP Kinases; Genes, ras; Humans; Liver Neoplasms; Mifepristone; Models, Biological; Proto-Oncogene Proteins c-akt; ras Proteins; Signal Transduction; Zebrafish | 2012 |
Mifepristone in the central nucleus of the amygdala reduces yohimbine stress-induced reinstatement of ethanol-seeking.
Topics: Alcohol-Induced Disorders, Nervous System; Alcoholism; Amygdala; Animals; Disease Models, Animal; Drug Interactions; Hormone Antagonists; Male; Mifepristone; Rats; Rats, Long-Evans; Secondary Prevention; Stress, Physiological; Yohimbine | 2012 |
Pharmacological interference with the glucocorticoid system influences symptoms and lifespan in a mouse model of Rett syndrome.
Topics: Animals; Corticosterone; Disease Models, Animal; Female; Gene Expression Regulation; Glucocorticoids; Immediate-Early Proteins; Life Expectancy; Male; Methyl-CpG-Binding Protein 2; Mice; Mifepristone; Motor Activity; Protein Serine-Threonine Kinases; Receptors, Glucocorticoid; Rett Syndrome; Rotarod Performance Test; Tacrolimus Binding Proteins | 2012 |
Gap junction dysfunction in the prefrontal cortex induces depressive-like behaviors in rats.
Topics: Analysis of Variance; Animals; Carbenoxolone; Connexin 43; Disease Models, Animal; Duloxetine Hydrochloride; Electroshock; Exploratory Behavior; Fluoxetine; Food Deprivation; Food Preferences; Gap Junctions; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Hormone Antagonists; Inhibition, Psychological; Isoquinolines; Male; Microscopy, Electron, Transmission; Mifepristone; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Restraint, Physical; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Social Isolation; Stress, Psychological; Sucrose; Sweetening Agents; Swimming; Thiophenes | 2012 |
Stress and corticosteroid modulation of seizures and synaptic inhibition in the hippocampus.
Topics: Adrenal Cortex Hormones; Aldosterone; Animals; Biophysics; Disease Models, Animal; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Kainic Acid; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Neural Inhibition; Patch-Clamp Techniques; Rats; Rats, Wistar; Reaction Time; Seizures; Spironolactone; Stress, Psychological; Synapses; Time Factors | 2012 |
Endogenous glucocorticoids inhibit myocardial inflammation induced by lipopolysaccharide: involvement of regulation of histone deacetylation.
Topics: Animals; Cytokines; Disease Models, Animal; Glucocorticoids; Histone Deacetylases; Hydrocortisone; Hydroxamic Acids; Inflammation; Lipopolysaccharides; Male; Mifepristone; Myocardium; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Signal Transduction | 2012 |
Binge-like ethanol consumption increases corticosterone levels and neurodegneration whereas occupancy of type II glucocorticoid receptors with mifepristone is neuroprotective.
Topics: Adrenalectomy; Alcohol-Induced Disorders, Nervous System; Alcoholic Intoxication; Analysis of Variance; Animals; Binge Drinking; Cholesterol; Corticosterone; Dentate Gyrus; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Implants; Entorhinal Cortex; Ethanol; Fluoresceins; Hormone Antagonists; Hypothalamo-Hypophyseal System; Male; Mifepristone; Neuroprotective Agents; Pituitary-Adrenal System; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Silver Staining; Stress, Physiological | 2014 |
An affective disorder in zebrafish with mutation of the glucocorticoid receptor.
Topics: Analysis of Variance; Animals; Animals, Genetically Modified; Anti-Anxiety Agents; Arginine; Brain; Cell Line, Transformed; Chlorocebus aethiops; Corticotropin-Releasing Hormone; Cysteine; Diazepam; Disease Models, Animal; Escape Reaction; Exploratory Behavior; Fluoxetine; Freezing Reaction, Cataleptic; Hormone Antagonists; Humans; Hydrocortisone; Interpersonal Relations; Mifepristone; Mood Disorders; Mutation; Psychomotor Agitation; Radioimmunoassay; Receptors, Glucocorticoid; Serotonin; Transfection; Zebrafish | 2013 |
Post-exposure sleep deprivation facilitates correctly timed interactions between glucocorticoid and adrenergic systems, which attenuate traumatic stress responses.
Topics: Acoustic Stimulation; Adrenergic Agonists; Analysis of Variance; Animals; Corticosterone; Dendrites; Disease Models, Animal; Electrocardiography; Epinephrine; Freezing Reaction, Cataleptic; Gene Expression Regulation; Heart Rate; Hippocampus; Hormone Antagonists; Male; Maze Learning; Mifepristone; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Reflex, Startle; Silver Staining; Sleep Deprivation; Stress Disorders, Post-Traumatic; Telemetry; Time Factors | 2012 |
Mifepristone, a blocker of glucocorticoid receptors, promotes photoreceptor death.
Topics: Animals; Apoptosis; Blotting, Western; Disease Models, Animal; Electroretinography; Hormone Antagonists; Immunohistochemistry; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred BALB C; Mifepristone; Photoreceptor Cells, Vertebrate; Receptors, Glucocorticoid; Retinal Degeneration | 2013 |
The anti-inflammatory effect of bee venom stimulation in a mouse air pouch model is mediated by adrenal medullary activity.
Topics: Adrenal Medulla; Adrenalectomy; Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents; Bee Venoms; Catecholamines; Cell Movement; Disease Models, Animal; Exudates and Transudates; Hormone Antagonists; Inflammation; Injections, Subcutaneous; Leukocytes; Male; Mice; Mice, Inbred ICR; Mifepristone; Receptors, Steroid; Tumor Necrosis Factor-alpha; Zymosan | 2003 |
Endogenous glucocorticoids attenuate Shiga toxin-2-induced toxicity in a mouse model of haemolytic uraemic syndrome.
Topics: Adrenal Glands; Animals; Corticosterone; Disease Models, Animal; Drug Administration Schedule; Glucocorticoids; Hemolytic-Uremic Syndrome; Hormone Antagonists; Kidney; Male; Mice; Mice, Inbred BALB C; Mifepristone; Receptors, Glucocorticoid; Shiga Toxin 2; Survival Rate; Urea | 2003 |
Stress-induced suppression of the immune system after withdrawal from chronic cocaine.
Topics: Adrenalectomy; Animals; Cell Division; Cocaine; Corticosterone; Disease Models, Animal; Dopamine Uptake Inhibitors; Hormone Antagonists; Hypersensitivity, Delayed; Immune System; Leukocytes; Male; Mifepristone; Rats; Stress, Physiological; Substance Withdrawal Syndrome; T-Lymphocyte Subsets; T-Lymphocytes | 2003 |
Enhancement of antitumor effect of cisplatin against human ovarian carcinoma cells by mifepristone in vivo.
Topics: Abortifacient Agents, Steroidal; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cisplatin; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Female; Humans; Mice; Mice, Nude; Mifepristone; Neoplasm Transplantation; Neoplasms, Experimental; Ovarian Neoplasms; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2003 |
A glucocorticoid response element in the LTR U3 region of Friend murine leukaemia virus variant FIS-2 enhances virus production in vitro and is a major determinant for sex differences in susceptibility to FIS-2 infection in vivo.
Topics: 3T3 Cells; Animals; Disease Models, Animal; Disease Susceptibility; Dose-Response Relationship, Drug; Female; Friend murine leukemia virus; Glucocorticoids; Hormone Antagonists; Leukemia, Experimental; Male; Mice; Mifepristone; Mutation; Response Elements; Retroviridae Infections; Sex Factors; Terminal Repeat Sequences; Tumor Virus Infections; Virulence; Virus Replication | 2003 |
Ovarian hyperstimulation syndrome-model rats; the manifestation and clinical implication.
Topics: Animals; Chorionic Gonadotropin; Disease Models, Animal; Female; Humans; Kallikrein-Kinin System; Mifepristone; Ovarian Hyperstimulation Syndrome; Progesterone; Rats; Rats, Wistar; Vascular Endothelial Growth Factor A | 2003 |
The glucocorticoid receptor as a potential target to reduce cocaine abuse.
Topics: Animals; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Hormone Antagonists; Male; Mice; Mice, Transgenic; Mifepristone; Motivation; Motor Activity; Neurons; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; RNA, Messenger; Self Administration | 2003 |
Expression of the type 1 and type 2 receptors for tumor necrosis factor after traumatic spinal cord injury in adult rats.
Topics: Animals; Antigens, CD; Blotting, Western; Disease Models, Animal; Disease Progression; Female; Hormone Antagonists; Methylprednisolone; Mifepristone; Neuroprotective Agents; Rats; Rats, Long-Evans; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Spinal Cord; Spinal Cord Injuries | 2003 |
The Drosophila homolog of Down's syndrome critical region 1 gene regulates learning: implications for mental retardation.
Topics: Animals; Animals, Genetically Modified; Chromosomes, Human, Pair 21; Conditioning, Operant; Disease Models, Animal; DNA-Binding Proteins; Down Syndrome; Drosophila; Electroshock; Gene Expression Regulation; Humans; Intracellular Signaling Peptides and Proteins; Learning; Memory; Mifepristone; Muscle Proteins; Mutation; Smell | 2003 |
A novel alkaloid antioxidant, Boldine and synthetic antioxidant, reduced form of RU486, inhibit the oxidation of LDL in-vitro and atherosclerosis in vivo in LDLR(-/-) mice.
Topics: Analysis of Variance; Animals; Antioxidants; Aporphines; Arteriosclerosis; Diet, Atherogenic; Disease Models, Animal; In Vitro Techniques; Lipid Peroxidation; Lipoproteins, LDL; Male; Mice; Mice, Knockout; Mifepristone; Oxidation-Reduction; Probability; Reference Values; Sensitivity and Specificity | 2004 |
Involvement of proopiomenalocortin-derived peptides in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats.
Topics: Adrenocorticotropic Hormone; alpha-MSH; Animals; Brain Chemistry; Disease Models, Animal; Heart Rate; Hemorrhage; Hindlimb; Histamine; Hypotension; Injections, Intraventricular; Injections, Subcutaneous; Male; Mifepristone; Peptides, Cyclic; Pro-Opiomelanocortin; Pyrimethamine; Rats; Rats, Wistar; Receptor, Melanocortin, Type 4; Regional Blood Flow; Renal Circulation; Shock, Hemorrhagic; Splanchnic Circulation; Time Factors | 2004 |
(-)-nicotine ameliorates corticosterone's potentiation of N-methyl-d-aspartate receptor-mediated cornu ammonis 1 toxicity.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Cell Survival; Corticosterone; Disease Models, Animal; Drug Interactions; Hippocampus; In Vitro Techniques; Male; Mifepristone; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic | 2004 |
Anti-inflammatory effect of acute stress on experimental colitis is mediated by cholecystokinin-B receptors.
Topics: Acute Disease; Animals; Colitis; Colon; Disease Models, Animal; Electric Stimulation; Ganglionic Blockers; Hexamethonium; Hypothalamo-Hypophyseal System; Injections, Intraventricular; Intestinal Mucosa; Male; Mifepristone; Neurotransmitter Agents; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Restraint, Physical; Stress, Physiological; Sympathetic Nervous System; Trinitrobenzenesulfonic Acid | 2004 |
Neuroendocrine responses mediate macrophage function after trauma.
Topics: Animals; Corticosterone; Cyclooxygenase 2; Disease Models, Animal; Female; Femoral Fractures; Macrophages; Mice; Mice, Inbred BALB C; Mifepristone; Neurosecretory Systems; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spleen; Wounds and Injuries | 2004 |
Endogenous glucocorticoids modulate neutrophil function in a murine model of haemolytic uraemic syndrome.
Topics: Animals; Apoptosis; Cell Adhesion; Cell Migration Inhibition; Collagen Type II; Disease Models, Animal; Fibrinogen; Glucocorticoids; Hemolytic-Uremic Syndrome; Hormone Antagonists; Leukocyte Count; Male; Mice; Mice, Inbred BALB C; Mifepristone; Neutrophils; Phagocytosis; Reactive Oxygen Species; Receptors, Glucocorticoid; Serum Albumin, Bovine; Shiga Toxin 2; Tetradecanoylphorbol Acetate | 2005 |
Progesterone increases blood pressure in spontaneous gestational hypertension in rats.
Topics: Animals; Aspartate Aminotransferases; Blood Pressure; Body Weight; Creatinine; Disease Models, Animal; Estrogens; Female; Hypertension, Pregnancy-Induced; Kidney; Male; Mifepristone; Pregnancy; Progesterone; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Systole | 2005 |
Dose response of RU486 in a novel rabbit model of noninfectious preterm birth: comparative efficacy of 3 routes of administration.
Topics: Abortifacient Agents, Steroidal; Animals; Cytokines; Disease Models, Animal; Female; Hydrocortisone; Injections, Intramuscular; Injections, Intraperitoneal; Injections, Subcutaneous; Mifepristone; Pregnancy; Premature Birth; Progesterone; Rabbits | 2005 |
Effects of progesterone blockade over cocaine-induced genital reflexes of paradoxical sleep-deprived male rats.
Topics: Analysis of Variance; Animals; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Ejaculation; Genitalia, Male; Hormone Antagonists; Male; Mifepristone; Penile Erection; Progesterone; Rats; Rats, Wistar; Reflex; Sleep; Sleep Deprivation | 2005 |
Significance of endogenous glucocorticoid sensitivity for airway eosinophilia in a murine model of allergy.
Topics: Administration, Intranasal; Airway Resistance; Animals; Asthma; Bone Marrow; Bronchi; Disease Models, Animal; Enzyme Inhibitors; Eosinophilia; Glucocorticoids; Hormone Antagonists; Leukocyte Count; Lung; Metyrapone; Mice; Mice, Inbred BALB C; Mifepristone; Ovalbumin; Receptors, Glucocorticoid; Respiratory Hypersensitivity; Respiratory Mucosa; Stress, Physiological | 2005 |
The effect of herbal medicine Toki-shakuyaku-san on blood pressure in an Nomega-nitro-L-arginine methyl ester-induced pre-eclampsia rat model during pregnancy and the postpartum period.
Topics: Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Disease Models, Animal; Drugs, Chinese Herbal; Estradiol; Female; Male; Mifepristone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pre-Eclampsia; Pregnancy; Progesterone; Rats; Rats, Sprague-Dawley | 2005 |
Effects of progesterone on apneic events during behaviorally defined sleep in male rats.
Topics: Aging; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Antagonism; Hormone Antagonists; Hyperventilation; Injections, Intraperitoneal; Male; Mifepristone; Plethysmography, Whole Body; Progesterone; Rats; Rats, Sprague-Dawley; Respiration; Sleep; Sleep Apnea Syndromes | 2005 |
Correlation of tumor phenotype with c-fms proto-oncogene expression in an in vivo intraperitoneal model for experimental human breast cancer metastasis.
Topics: Animals; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Dexamethasone; Disease Models, Animal; Female; Gene Expression; Hormone Antagonists; Humans; Mice; Mice, Inbred BALB C; Mice, SCID; Mifepristone; Peritoneal Cavity; Phenotype; Proto-Oncogene Mas; Receptor, Macrophage Colony-Stimulating Factor; Up-Regulation | 2005 |
Systemic and intra-amygdala administration of glucocorticoid agonist and antagonist modulate extinction of conditioned fear.
Topics: Amygdala; Animals; Anxiety Disorders; Avoidance Learning; Conditioning, Psychological; Dexamethasone; Disease Models, Animal; Extinction, Psychological; Fear; Glucocorticoids; Hormone Antagonists; Male; Mifepristone; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Reflex, Startle | 2006 |
Effects of glucocorticoid receptor antagonists on allodynia and hyperalgesia in mouse model of neuropathic pain.
Topics: Animals; Behavior, Animal; Calcium Channels, N-Type; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Profiling; Hormone Antagonists; Hyperalgesia; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mifepristone; Motor Activity; Neuralgia; Oligonucleotide Array Sequence Analysis; Pain; Pain Threshold; Receptors, Glucocorticoid; Spinal Cord Injuries; Time Factors | 2005 |
Protein synthesis and the mechanisms of lasting change in anxiety induced by severe stress.
Topics: Analysis of Variance; Animals; Anisomycin; Anti-Anxiety Agents; Anxiety; Association Learning; Cats; Chlordiazepoxide; Disease Models, Animal; Exploratory Behavior; Habituation, Psychophysiologic; Hormone Antagonists; Male; Memory; Mifepristone; Predatory Behavior; Protein Biosynthesis; Protein Synthesis Inhibitors; Random Allocation; Rats; Rats, Long-Evans; Receptors, Glucocorticoid; Reflex, Startle; Severity of Illness Index; Stress, Psychological | 2006 |
Aortic function is compromised in a rat model of polycystic ovary syndrome.
Topics: Acetylcholine; Animals; Aorta; Blood Pressure; Disease Models, Animal; Endothelium, Vascular; Female; Insulin; Insulin Secretion; Luteinizing Hormone; Mifepristone; Muscle, Smooth, Vascular; Nitroprusside; Phenylephrine; Polycystic Ovary Syndrome; Rats; Rats, Sprague-Dawley | 2006 |
NF-kappaB mediated glucocorticoid response in the inner ear after acoustic trauma.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Auditory Threshold; Blotting, Northern; Disease Models, Animal; Drug Interactions; Ear, Inner; Enzyme Inhibitors; Glucocorticoids; Hearing Loss, Noise-Induced; Immunohistochemistry; In Situ Hybridization; Male; Metyrapone; Mice; Mice, Inbred CBA; Mifepristone; Neurons; NF-kappa B; Receptors, Glucocorticoid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spiral Ganglion; Time Factors | 2006 |
Facilitation of cardiac vagal activity by CRF-R1 antagonists during swim stress in rats.
Topics: Animals; Bradycardia; Cholinergic Antagonists; Corticotropin-Releasing Hormone; Death, Sudden, Cardiac; Disease Models, Animal; Exercise Tolerance; Fatigue; Heart Rate; Hypothalamo-Hypophyseal System; Hypothermia, Induced; Male; Mifepristone; Peptide Fragments; Psychomotor Agitation; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Stress, Psychological; Swimming; Vagus Nerve; Vagus Nerve Diseases | 2006 |
Natural and synthetic progestins accelerate 7,12-dimethylbenz[a]anthracene-initiated mammary tumors and increase angiogenesis in Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Implants; Immunohistochemistry; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mifepristone; Neovascularization, Pathologic; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, Progesterone; Time Factors; Vascular Endothelial Growth Factors | 2006 |
Morphine conditioned place preference depends on glucocorticoid receptors in both hippocampus and nucleus accumbens.
Topics: Animals; Conditioning, Psychological; Cues; Dimethyl Sulfoxide; Disease Models, Animal; Dose-Response Relationship, Drug; Glucocorticoids; Hippocampus; Hormone Antagonists; Male; Memory; Mifepristone; Morphine; Morphine Dependence; Motivation; Narcotics; Nerve Net; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Reward; Solvents | 2006 |
Glucocorticoid mechanisms may contribute to ECT-induced retrograde amnesia.
Topics: Amnesia, Retrograde; Animals; Avoidance Learning; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Hippocampus; Hormone Antagonists; Male; Mental Recall; Mifepristone; Premedication; Rats; Rats, Wistar; Receptors, Glucocorticoid | 2007 |
Nitric oxide up-regulates the glucocorticoid receptor and blunts the inflammatory reaction in porcine endotoxin sepsis.
Topics: Administration, Inhalation; Animals; Anti-Inflammatory Agents; Blood Gas Analysis; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Hormone Antagonists; Hydrocortisone; Immunohistochemistry; Inflammation; Infusions, Intravenous; Lipopolysaccharides; Mifepristone; Nitric Oxide; Prospective Studies; Pulmonary Wedge Pressure; Random Allocation; Receptors, Glucocorticoid; Respiratory Distress Syndrome; Sepsis; Swine; Up-Regulation | 2007 |
Involvement of noradrenergic and corticoid receptors in the consolidation of the lasting anxiogenic effects of predator stress.
Topics: Adrenergic beta-Antagonists; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Association Learning; Chi-Square Distribution; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Propranolol; Random Allocation; Rats; Receptors, Adrenergic, beta; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Reflex, Startle; Statistics, Nonparametric; Stress Disorders, Post-Traumatic; Stress, Psychological | 2007 |
Mifepristone repairs region-dependent alteration of synapsin I in hippocampus in rat model of depression.
Topics: Analysis of Variance; Animals; Behavior, Animal; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Food Preferences; Hippocampus; Hormone Antagonists; Male; Mifepristone; Random Allocation; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Statistics as Topic; Synapsins | 2007 |
Glucocorticoid receptor activation is involved in producing abnormal phenotypes of single-prolonged stress rats: a putative post-traumatic stress disorder model.
Topics: Amygdala; Animals; Anxiety Disorders; Avoidance Learning; Cell Death; Corticosterone; Disease Models, Animal; Fear; Hippocampus; Hypothalamo-Hypophyseal System; Long-Term Potentiation; Male; Memory; Memory Disorders; Mifepristone; Nerve Degeneration; Phenotype; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Reflex, Abnormal; Reflex, Startle; Stress Disorders, Post-Traumatic; Stress, Psychological | 2007 |
Corticosterone mediates electroacupuncture-produced anti-edema in a rat model of inflammation.
Topics: Adrenal Glands; Adrenalectomy; Animals; Corticosterone; Disease Models, Animal; Edema; Electroacupuncture; Freund's Adjuvant; Hormone Antagonists; Hyperalgesia; Inflammation; Male; Mifepristone; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Reference Values | 2007 |
Opposite effects of glucocorticoid receptor activation on hippocampal CA1 dendritic complexity in chronically stressed and handled animals.
Topics: Animals; Behavior, Animal; Corticosterone; Dendrites; Disease Models, Animal; Handling, Psychological; Hippocampus; Hormone Antagonists; In Vitro Techniques; Male; Mifepristone; Multivariate Analysis; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Glucocorticoid; Stress, Psychological | 2008 |
CRF1 not glucocorticoid receptors mediate prepulse inhibition deficits in mice overexpressing CRF.
Topics: Acoustic Stimulation; Adrenalectomy; Animals; Benzodioxoles; Depressive Disorder, Major; Disease Models, Animal; Gene Expression; Genotype; Hormone Antagonists; Infusions, Parenteral; Male; Mice; Mice, Transgenic; Mifepristone; Psychotic Disorders; Receptors, Corticotropin-Releasing Hormone; Receptors, Glucocorticoid; Reflex, Startle; Steroids | 2008 |
Time-dependent effect of epidural steroid on pain behavior induced by chronic compression of dorsal root ganglion in rats.
Topics: Animals; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Ganglia, Spinal; Glucocorticoids; Hormone Antagonists; Hyperalgesia; Injections, Epidural; Male; Mifepristone; Nerve Compression Syndromes; Neuralgia; Physical Stimulation; Rats; Rats, Sprague-Dawley; Time Factors; Triamcinolone | 2007 |
Effects of progesterone on FSH-stimulated indomethacin ulcers in rats.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Estrogens; Female; Follicle Stimulating Hormone; Hormone Antagonists; Indomethacin; Mifepristone; Ovariectomy; Progesterone; Rats; Rats, Wistar; Stomach Ulcer | 2008 |
Glucocorticoid availability in colonic inflammation of rat.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Animals; Budesonide; Carbenoxolone; Colitis; Colon; Corticosterone; Cyclooxygenase 2; Disease Models, Animal; Glucocorticoids; Hormone Antagonists; Interleukin-1beta; Male; Mifepristone; Mucin-2; Mucins; Peroxidase; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2008 |
Metyrapone and mifepristone reverse recognition memory loss induced by spontaneous morphine withdrawal in mice.
Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Glucocorticoids; Hormone Antagonists; Injections, Subcutaneous; Male; Memory; Memory Disorders; Metyrapone; Mice; Mifepristone; Morphine; Receptors, Glucocorticoid; Recognition, Psychology; Steroid 11-beta-Hydroxylase; Substance Withdrawal Syndrome; Time Factors | 2008 |
Low-frequency electroacupuncture suppresses carrageenan-induced paw inflammation in mice via sympathetic post-ganglionic neurons, while high-frequency EA suppression is mediated by the sympathoadrenal medullary axis.
Topics: Adrenal Medulla; Adrenalectomy; Adrenergic Agents; Animals; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Radiation; Edema; Electric Stimulation; Electroacupuncture; Ganglia, Sympathetic; Hormone Antagonists; Inflammation; Male; Mice; Mice, Inbred ICR; Mifepristone; Neurons; Pain Threshold; Peroxidase; Time Factors | 2008 |
Anti-inflammatory effect of theophylline in rats and its involvement of the glucocorticoid-glucocorticoid receptor system.
Topics: Aminoglutethimide; Animals; Anti-Inflammatory Agents; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Glucocorticoids; Hormone Antagonists; Injections, Subcutaneous; Male; Mifepristone; Rats; Rats, Wistar; Receptors, Glucocorticoid; Theophylline | 2008 |
Effects of glucocorticoid agonist and antagonist on the pathogenesis of L-arginine-induced acute pancreatitis in rat.
Topics: Acute Disease; Amylases; Animals; Arginine; Disease Models, Animal; Glucocorticoids; Inflammation; Interleukin-6; L Cells; Macrophage Migration-Inhibitory Factors; Male; Methylprednisolone; Mice; Mifepristone; Pancreatitis; Rats; Rats, Wistar | 2008 |
p11 is up-regulated in the forebrain of stressed rats by glucocorticoid acting via two specific glucocorticoid response elements in the p11 promoter.
Topics: Animals; Animals, Newborn; Annexin A2; Cells, Cultured; Chromatin Immunoprecipitation; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Glucocorticoids; Hormone Antagonists; Humans; Male; Mifepristone; Nuclear Proteins; Promoter Regions, Genetic; Prosencephalon; Rats; Rats, Sprague-Dawley; S100 Proteins; Stress, Psychological; Time Factors; Up-Regulation | 2008 |
RU486 did not exacerbate cytokine release in mice challenged with LPS nor in db/db mice.
Topics: Adrenocorticotropic Hormone; Animals; Blood Glucose; Chemokine CCL2; Corticosterone; Diabetes Mellitus, Type 2; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Glucose-6-Phosphatase; Hormone Antagonists; Hypoglycemic Agents; Interleukin-6; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mifepristone; Obesity; Protein Serine-Threonine Kinases; Receptors, Glucocorticoid; Receptors, Leptin; Tumor Necrosis Factor-alpha | 2008 |
Inhibition of some aspects of acute inflammation of guinea-pig lung by intraperitoneal dexamethasone and mifepristone: demonstration of agonist activity of mifepristone in the guinea-pig.
Topics: Acute Disease; Animals; Blood Proteins; Bronchoalveolar Lavage Fluid; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Eosinophilia; Guinea Pigs; Histamine; Injections, Intraperitoneal; Lipopolysaccharides; Male; Mifepristone; Neutrophils; Platelet Activating Factor; Pneumonia; Skin | 1995 |
Use of normal C57BL/6 mice with established Mycobacterium avium infections as an alternative model for evaluation of antibiotic activity.
Topics: Animals; Anti-Bacterial Agents; Clarithromycin; Colony Count, Microbial; Disease Models, Animal; Female; Glucocorticoids; Humans; Lung; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Mifepristone; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Spleen | 1995 |
Glucocorticoid receptor blockade reverses postinjury macrophage suppression.
Topics: Administration, Oral; Animals; Dinoprostone; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Femoral Fractures; Interleukin-6; Macrophage Activation; Macrophages, Peritoneal; Mice; Mice, Inbred Strains; Mifepristone; Premedication; Random Allocation; Receptors, Glucocorticoid; Stress, Physiological; Superoxides; Tumor Necrosis Factor-alpha | 1994 |
Opioids and corticosteroids involvement in the regulation of the neocortical spindling episodes in DBA/2J mice.
Topics: Adrenal Cortex; Animals; Cerebral Cortex; Corticosterone; Cycloheximide; Dexamethasone; Disease Models, Animal; Disease Susceptibility; Electroencephalography; Epilepsy; Genetic Predisposition to Disease; Male; Mice; Mice, Inbred DBA; Mifepristone; Morphine; Naltrexone | 1993 |
Suppression of splenic natural killer cell activity in a mouse model for binge drinking. II. Role of the neuroendocrine system.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alcoholism; Animals; Azides; Benzodiazepines; Carbolines; Catecholamines; Corticosterone; Diazepam; Disease Models, Animal; Female; GABA-A Receptor Agonists; Glucocorticoids; Immunity, Cellular; Immunity, Innate; Killer Cells, Natural; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mifepristone; Nadolol; Naltrexone; Neurosecretory Systems; Oxidopamine; Phentolamine; Picrotoxin; Propranolol; Receptors, GABA-A; Spleen; Sympathetic Nervous System | 1996 |
RU486-treated rats show endocrine and morphological responses to therapies analogous to responses of women with polycystic ovary syndrome treated with similar therapies.
Topics: Androgen Antagonists; Animals; Bromocriptine; Disease Models, Animal; Dopamine Agonists; Estrogen Antagonists; Female; Flutamide; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Hormone Antagonists; Humans; Mifepristone; Ovary; Ovulation; Polycystic Ovary Syndrome; Progesterone; Rats; Rats, Wistar; Tamoxifen | 1996 |
Regulation of chronic relapsing experimental allergic encephalomyelitis by endogenous and exogenous glucocorticoids.
Topics: Animals; Chronic Disease; Corticosterone; Dexamethasone; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Glucocorticoids; Hormone Antagonists; Hypersensitivity, Delayed; Male; Mice; Mifepristone; Neuroimmunomodulation; Rats; Recurrence; Species Specificity | 1997 |
Role of progesterone in capillary permeability in hyperstimulated rats.
Topics: Adrenocorticotropic Hormone; Animals; Capillary Permeability; Chorionic Gonadotropin; Disease Models, Animal; Estradiol; Female; Gonadotropins, Equine; Hormone Antagonists; Humans; Mifepristone; Ovarian Hyperstimulation Syndrome; Progesterone; Rats; Rats, Wistar | 1997 |
Thermal injury induces thymocyte apoptosis in the rat.
Topics: Adrenalectomy; Animals; Apoptosis; Burns; Corticosterone; Disease Models, Animal; Glucocorticoids; Glutathione; Hormone Antagonists; Male; Mifepristone; Organ Size; Rats; Rats, Wistar; T-Lymphocytes; Thymus Gland; Time Factors | 1998 |
Mechanism of suppressed neutrophil mobilization in a mouse model for binge drinking: role of glucocorticoids.
Topics: Alcohol Drinking; Animals; Corticosterone; Disease Models, Animal; Ethanol; Female; Inflammation; Macrophages, Peritoneal; Mice; Mice, Inbred Strains; Mifepristone; Neutrophil Activation; Neutrophils; Peritoneal Cavity; Propionibacterium acnes; Tumor Necrosis Factor-alpha | 1998 |
In vitro modulation of primate coronary vascular muscle cell reactivity by ovarian steroid hormones.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcium Signaling; Coronary Vasospasm; Coronary Vessels; Disease Models, Animal; Disease Susceptibility; Enzyme Activation; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Hormone Antagonists; Hormone Replacement Therapy; Humans; Macaca mulatta; Microscopy, Confocal; Microscopy, Fluorescence; Mifepristone; Muscle Proteins; Muscle, Smooth, Vascular; Ovariectomy; Postmenopause; Progesterone; Protein Kinase C; Receptors, Estrogen; Receptors, Progesterone; Serotonin; Thromboxane A2; Vasoconstriction | 1998 |
Involvement of ovarian kinin-kallikrein system in the pathophysiology of ovarian hyperstimulation syndrome: studies in a rat model.
Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Capillary Permeability; Chorionic Gonadotropin; Disease Models, Animal; Estradiol; Evans Blue; Female; Hormone Antagonists; Kallikreins; Kinins; Mifepristone; Ovarian Hyperstimulation Syndrome; Ovary; Peritoneum; Progesterone; Protease Inhibitors; Rats; Rats, Wistar | 1998 |
Growth inhibition of human in vitro and mouse in vitro and in vivo mammary tumor models by retinoids in comparison with tamoxifen and the RU-486 anti-progestagen.
Topics: Alitretinoin; Animals; Anticarcinogenic Agents; Apoptosis; Benzoates; Bexarotene; Breast Neoplasms; Cell Division; Disease Models, Animal; Female; Fenretinide; Hormone Antagonists; Humans; Mammary Neoplasms, Animal; Mice; Mice, Inbred C57BL; Mifepristone; Retinoids; Tamoxifen; Tetrahydronaphthalenes; Tretinoin; Tumor Cells, Cultured | 1998 |
Adrenocorticotrophin-induced hypertension: effects of mineralocorticoid and glucocorticoid receptor antagonism.
Topics: Adrenocorticotropic Hormone; Animals; Anti-Bacterial Agents; Blood Pressure; Disease Models, Animal; Drug Therapy, Combination; Hypertension; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Potassium; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Sodium; Spironolactone; Troleandomycin | 1999 |
Antitumor activity of mifepristone in the human LNCaP, LNCaP-C4, and LNCaP-C4-2 prostate cancer models in nude mice.
Topics: Androgens; Animals; Cell Division; Disease Models, Animal; Disease Progression; Hormone Antagonists; Humans; Male; Mice; Mice, Nude; Mifepristone; Prostatic Neoplasms; Random Allocation; Tumor Cells, Cultured | 2000 |
Labeling of the glucocorticoid receptor and Na,K-ATPase in a rat otitis media model.
Topics: Acute Disease; Animals; Disease Models, Animal; Drug Labeling; Ear, Inner; Ear, Middle; Glucocorticoids; Hormone Antagonists; Immunoenzyme Techniques; Immunohistochemistry; Male; Mifepristone; Mucous Membrane; Otitis Media, Suppurative; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Sodium-Potassium-Exchanging ATPase; Streptococcal Infections | 2000 |
Glucocorticoid-induced, caspase-dependent organ apoptosis early after burn injury.
Topics: Animals; Antibodies, Monoclonal; Apoptosis; Burns; Caspase 3; Caspases; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Corticosterone; Dexamethasone; Disease Models, Animal; Fas Ligand Protein; Female; Flow Cytometry; Gene Expression Regulation, Enzymologic; Glucocorticoids; Hormone Antagonists; In Situ Nick-End Labeling; Liver; Lung; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mifepristone; RNA, Messenger; Specific Pathogen-Free Organisms; Spleen; Thymus Gland; Tumor Necrosis Factor-alpha | 2000 |
Glucocorticoid receptor antagonist RU 486 treatment reduces periodontitis in Fischer 344 rats.
Topics: Animals; Disease Models, Animal; Glucocorticoids; Hormone Antagonists; Hypothalamo-Hypophyseal System; Male; Mifepristone; Neuroimmunomodulation; Periodontitis; Pituitary-Adrenal System; Random Allocation; Rats; Rats, Inbred F344 | 2000 |
Glucocorticoid and Fas ligand induced mucosal lymphocyte apoptosis after burn injury.
Topics: Analysis of Variance; Animals; Apoptosis; B-Lymphocytes; Burns; Disease Models, Animal; Fas Ligand Protein; Female; Glucocorticoids; Intestinal Mucosa; Lymphoid Tissue; Membrane Glycoproteins; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mifepristone; Peyer's Patches; T-Lymphocytes | 2000 |
Glucocorticoid receptor-mediated suppression of activator protein-1 activation and matrix metalloproteinase expression after spinal cord injury.
Topics: Animals; Binding, Competitive; Blotting, Western; Disease Models, Animal; Female; Glucocorticoids; Hormone Antagonists; Immunohistochemistry; Matrix Metalloproteinase 1; Matrix Metalloproteinase 9; Methylprednisolone; Mifepristone; Neuroprotective Agents; NF-kappa B; Oligonucleotides, Antisense; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Long-Evans; Receptors, Glucocorticoid; Spinal Cord Injuries; Transcription Factor AP-1 | 2001 |
Focal activation of a mutant allele defines the role of stem cells in mosaic skin disorders.
Topics: Animals; Disease Models, Animal; Female; Gene Targeting; Humans; Hyperkeratosis, Epidermolytic; Integrases; Keratin-10; Keratins; Mice; Mice, Transgenic; Mifepristone; Mosaicism; Point Mutation; Skin; Stem Cells; Viral Proteins | 2001 |
An inducible mouse model for epidermolysis bullosa simplex: implications for gene therapy.
Topics: Animals; Blotting, Southern; Disease Models, Animal; Epidermolysis Bullosa Simplex; Gene Expression Regulation; Genetic Therapy; Humans; Integrases; Keratin-14; Keratins; Luteolytic Agents; Mice; Mice, Transgenic; Microscopy, Fluorescence; Mifepristone; Reverse Transcriptase Polymerase Chain Reaction; Skin; Viral Proteins | 2001 |
The ovarian hormones and absence epilepsy: a long-term EEG study and pharmacological effects in a genetic absence epilepsy model.
Topics: Animals; Behavior, Animal; Circadian Rhythm; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; Estradiol; Estrous Cycle; Female; Gonadal Steroid Hormones; Hormone Antagonists; Mifepristone; Ovary; Progesterone; Rats; Rats, Inbred Strains | 2001 |
Immortalized chromaffin cells disimmortalized with Cre/lox site-directed recombination for use in cell therapy for pain after partial nerve injury.
Topics: Animals; Antigens, Viral, Tumor; Cell Count; Cells, Cultured; Chromaffin Cells; Disease Models, Animal; Dopamine beta-Hydroxylase; Gene Expression; Genetic Vectors; Hyperalgesia; Integrases; Mifepristone; Mutagenesis, Site-Directed; Norepinephrine; Oncogenes; Pain; Pain Management; Phenylethanolamine N-Methyltransferase; Rats; Rats, Inbred WF; Rats, Sprague-Dawley; Recombination, Genetic; Sciatic Neuropathy; Temperature; Thymidine Kinase; Transfection; Treatment Outcome; Tyrosine 3-Monooxygenase; Viral Proteins | 2002 |
Social stress exacerbates focal cerebral ischemia in mice.
Topics: Animals; Behavior, Animal; Brain Ischemia; Cognition; Corticosterone; Disease Models, Animal; Disease Progression; Hormone Antagonists; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Mifepristone; Motor Activity; Reaction Time; Receptors, Glucocorticoid; Reperfusion; Social Behavior; Social Dominance; Stress, Physiological | 2002 |
Sparfloxacin, ethambutol, and cortisol receptor inhibitor RU-40 555 treatment for disseminated Mycobacterium avium complex infection of normal C57BL/6 mice.
Topics: Animals; Anti-Bacterial Agents; Disease Models, Animal; Drug Therapy, Combination; Ethambutol; Feasibility Studies; Female; Fluoroquinolones; Glucocorticoids; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Mifepristone; Mycobacterium avium; Quinolones; Receptors, Glucocorticoid; Spleen; Time Factors; Tuberculosis | 1992 |
Modification of septic shock in mice by the antiglucocorticoid RU 38486.
Topics: Animals; Dexamethasone; Disease Models, Animal; Endotoxins; Lipopolysaccharides; Male; Mice; Mice, Inbred Strains; Mifepristone; Peritonitis; Shock, Septic | 1992 |
Treatment of breast cancer with different antiprogestins: preclinical and clinical studies.
Topics: Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Disease Models, Animal; Drug Therapy, Combination; Gonadotropin-Releasing Hormone; Hormones; Humans; Middle Aged; Mifepristone; Organ Size; Rats; Receptors, Steroid; Tamoxifen | 1990 |
Reversal of the anti-inflammatory effects of dexamethasone by the glucocorticoid antagonist RU 38486.
Topics: Animals; Carrageenan; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Estrenes; Inflammation; Male; Mifepristone; Pleurisy; Rats; Rats, Inbred Strains | 1988 |