Page last updated: 2024-08-23

mifepristone and Depression, Endogenous

mifepristone has been researched along with Depression, Endogenous in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19904 (20.00)18.7374
1990's3 (15.00)18.2507
2000's9 (45.00)29.6817
2010's4 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jiang, H; Liu, D; Liu, Y; Pan, F; Wang, R; Xu, J1
Li, YY; Liu, BP; Liu, FM; Peng, ZL; Song, C; Wang, HY; Zhang, C; Zhang, YP1
Jiang, H; Liu, D; Liu, Y; Pan, F; Wang, R; Wang, W; Xu, J1
Belanoff, JK; Blasey, CM; Block, TS; Roe, RL1
Charney, DS; Drevets, WC; Gold, PW1
Song, C1
Nemeroff, CB1
Schatzberg, AF1
Rothschild, AJ1
Craft, TK; DeVries, AC1
Carroll, BJ; Rubin, RT1
Benton, T; Douglas, SD; Dubé, B; Evans, DL; Gettes, DR; Lai, JP; Lynch, KG; Metzger, D; Tustin, NB1
Filipini, D; Ghadirian, AM; Murphy, BE1
Murphy, BE1
Belanoff, J; Chu, JW; Feldman, D; Hoffman, AR; Matthias, DF; Schatzberg, A1
Carroll, BJ; Krishnan, KR; Nemeroff, CB; Reed, D; Ritchie, JC; Saunders, WB; Wilson, WH1
Brandt, HA; Calabrese, JR; Chrousos, GP; Demitrack, MA; Geracioti, TD; Gold, PW; Kalogeras, K; Kling, MA; Perini, GI; Whitfield, HJ1
Sikes, CR; Stokes, PE2
Allilaire, JF; Ammar, S; Baulieu, EE; Lecrubier, Y; Widlocher, D1

Reviews

6 review(s) available for mifepristone and Depression, Endogenous

ArticleYear
The effect of thymectomy and IL-1 on memory: implications for the relationship between immunity and depression.
    Brain, behavior, and immunity, 2002, Volume: 16, Issue:5

    Topics: Animals; Corticosterone; Cytokines; Depressive Disorder; Disease Models, Animal; Dopamine; Hormone Antagonists; Interleukin-1; Limbic System; Lymphocytes; Macrophages; Memory Disorders; Mifepristone; Norepinephrine; Rats; Receptors, Glucocorticoid; Serotonin; Thymectomy; Thymus Gland

2002
New directions in the development of antidepressants: the interface of neurobiology and psychiatry.
    Human psychopharmacology, 2002, Volume: 17 Suppl 1

    Topics: Animals; Antidepressive Agents; Brain; Corticotropin-Releasing Hormone; Depressive Disorder; Hormone Antagonists; Humans; Mifepristone; Receptors, Corticotropin-Releasing Hormone; Receptors, Glucocorticoid

2002
New approaches to managing psychotic depression.
    The Journal of clinical psychiatry, 2003, Volume: 64 Suppl 1

    Topics: Affective Disorders, Psychotic; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Clinical Trials as Topic; Depressive Disorder; Drug Therapy, Combination; Electroconvulsive Therapy; Fluoxetine; Humans; Lithium; Mifepristone; Olanzapine; Pirenzepine; Receptors, Glucocorticoid; Treatment Outcome

2003
Antiglucocorticoid therapies in major depression: a review.
    Psychoneuroendocrinology, 1997, Volume: 22 Suppl 1

    Topics: Animals; Antidepressive Agents; Depressive Disorder; Dexamethasone; Glucocorticoids; Hormone Antagonists; Humans; Mifepristone

1997
The hypothalamic-pituitary-adrenocortical axis in major depression.
    Endocrinology and metabolism clinics of North America, 1988, Volume: 17, Issue:1

    Topics: Adrenocorticotropic Hormone; Body Fluids; Corticotropin-Releasing Hormone; Depressive Disorder; Estrenes; Humans; Hypothalamo-Hypophyseal System; Metyrapone; Mifepristone; Physostigmine; Pituitary-Adrenal Function Tests; Pituitary-Adrenal System; Vasopressins

1988
The hypothalamic-pituitary-adrenocortical axis in major depression.
    Neurologic clinics, 1988, Volume: 6, Issue:1

    Topics: Adrenocorticotropic Hormone; Brain; Corticotropin-Releasing Hormone; Depressive Disorder; Estrenes; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Metyrapone; Mifepristone; Pituitary-Adrenal Function Tests; Pituitary-Adrenal System; Receptors, Glucocorticoid; Saliva

1988

Trials

4 trial(s) available for mifepristone and Depression, Endogenous

ArticleYear
Efficacy and safety of mifepristone for the treatment of psychotic depression.
    Journal of clinical psychopharmacology, 2011, Volume: 31, Issue:4

    Topics: Adult; Depressive Disorder; Dizziness; Double-Blind Method; Female; Headache; Humans; Male; Middle Aged; Mifepristone; Psychotic Disorders; Treatment Outcome

2011
Selective serotonin reuptake inhibitor and substance P antagonist enhancement of natural killer cell innate immunity in human immunodeficiency virus/acquired immunodeficiency syndrome.
    Biological psychiatry, 2008, May-01, Volume: 63, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; Adult; Biphenyl Compounds; Citalopram; Depressive Disorder; Depressive Disorder, Major; Female; Glucocorticoids; HIV Seropositivity; Hormone Antagonists; Humans; Immunity, Innate; Killer Cells, Natural; Lymphocyte Count; Middle Aged; Mifepristone; Personality Inventory; Selective Serotonin Reuptake Inhibitors; Substance P; T-Lymphocytes, Cytotoxic; Viral Load

2008
Possible use of glucocorticoid receptor antagonists in the treatment of major depression: preliminary results using RU 486.
    Journal of psychiatry & neuroscience : JPN, 1993, Volume: 18, Issue:5

    Topics: Adrenocorticotropic Hormone; Adult; Dehydroepiandrosterone; Depressive Disorder; Female; Humans; Hydrocortisone; Male; Middle Aged; Mifepristone; Personality Inventory; Receptors, Glucocorticoid

1993
Effects of glucocorticoid antagonism with RU 486 on pituitary-adrenal function in patients with major depression: time-dependent enhancement of plasma ACTH secretion.
    Psychopharmacology bulletin, 1989, Volume: 25, Issue:3

    Topics: Adrenocorticotropic Hormone; Adult; Depressive Disorder; Female; Glucocorticoids; Humans; Male; Mifepristone; Pituitary-Adrenal Function Tests; Pituitary-Adrenal System; Time Factors

1989

Other Studies

10 other study(ies) available for mifepristone and Depression, Endogenous

ArticleYear
FKBP5 and specific microRNAs via glucocorticoid receptor in the basolateral amygdala involved in the susceptibility to depressive disorder in early adolescent stressed rats.
    Journal of psychiatric research, 2017, Volume: 95

    Topics: Age Factors; Animals; Basolateral Nuclear Complex; Behavior, Animal; Depressive Disorder; Dexamethasone; Disease Models, Animal; Disease Susceptibility; Glucocorticoids; Hormone Antagonists; Male; Memory Disorders; MicroRNAs; Mifepristone; Rats; Rats, Wistar; Receptors, Glucocorticoid; Stress, Psychological; Tacrolimus Binding Proteins

2017
Mifepristone attenuates depression-like changes induced by chronic central administration of interleukin-1β in rats.
    Behavioural brain research, 2018, 07-16, Volume: 347

    Topics: Amygdala; Anhedonia; Animals; Antidepressive Agents; Corticosterone; Depressive Disorder; Disease Models, Animal; Hormone Antagonists; Interleukin-1beta; Male; Mifepristone; Motor Activity; Nerve Growth Factors; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Recombinant Proteins; RNA, Messenger

2018
Short- and long-term alterations of FKBP5-GR and specific microRNAs in the prefrontal cortex and hippocampus of male rats induced by adolescent stress contribute to depression susceptibility.
    Psychoneuroendocrinology, 2019, Volume: 101

    Topics: Age Factors; Animals; Brain; Depression; Depressive Disorder; Disease Susceptibility; Glucocorticoids; Hippocampus; Hypothalamo-Hypophyseal System; Male; MicroRNAs; Mifepristone; Pituitary-Adrenal System; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, Glucocorticoid; Stress, Psychological; Tacrolimus Binding Proteins

2019
New insights into the role of cortisol and the glucocorticoid receptor in severe depression.
    Biological psychiatry, 2002, Sep-01, Volume: 52, Issue:5

    Topics: Amygdala; Antidepressive Agents; Depressive Disorder; Hippocampus; Humans; Hydrocortisone; Hypothalamus; Mifepristone; Prefrontal Cortex; Receptors, Glucocorticoid

2002
Conflict-of-interest charge.
    The American journal of psychiatry, 2004, Volume: 161, Issue:9

    Topics: Affective Disorders, Psychotic; Book Reviews as Topic; Conflict of Interest; Depressive Disorder; Disclosure; Humans; Mifepristone; Scientific Misconduct; Treatment Outcome

2004
Role of IL-1 in poststroke depressive-like behavior in mice.
    Biological psychiatry, 2006, Oct-15, Volume: 60, Issue:8

    Topics: Animals; Antimetabolites; Depressive Disorder; Drinking Behavior; Glucocorticoids; Hormone Antagonists; Infarction, Middle Cerebral Artery; Injections, Intraventricular; Interleukin-1; Male; Metyrapone; Mice; Mice, Inbred C57BL; Mifepristone; Receptors, Glucocorticoid; Receptors, Interleukin-1; Stroke; Sucrose

2006
Is mifepristone useful in psychotic depression?
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:12

    Topics: Adrenocorticotropic Hormone; Affective Disorders, Psychotic; Antidepressive Agents; Clinical Trials as Topic; Data Interpretation, Statistical; Depressive Disorder; Hormone Antagonists; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Mifepristone; Patient Selection; Receptors, Glucocorticoid; Reproducibility of Results; Treatment Outcome

2006
Successful long-term treatment of refractory Cushing's disease with high-dose mifepristone (RU 486).
    The Journal of clinical endocrinology and metabolism, 2001, Volume: 86, Issue:8

    Topics: Adrenocorticotropic Hormone; Black or African American; Bone Density; Brain; California; Cholesterol; Cushing Syndrome; Depressive Disorder; Glycated Hemoglobin; Heart Failure; Hormone Antagonists; Humans; Hydrocortisone; Magnetic Resonance Imaging; Male; Mental Status Schedule; Middle Aged; Mifepristone; Osteocalcin; Ventricular Function, Left

2001
RU486 in depression.
    Progress in neuro-psychopharmacology & biological psychiatry, 1992, Volume: 16, Issue:6

    Topics: Adrenocorticotropic Hormone; Adult; Aged; Antidepressive Agents; Depressive Disorder; Dexamethasone; Female; Humans; Hydrocortisone; Male; Middle Aged; Mifepristone

1992
Afternoon increase in plasma cortisol in depressed patients receiving an antiglucocorticosteroid in the morning.
    The American journal of psychiatry, 1986, Volume: 143, Issue:1

    Topics: Adult; Circadian Rhythm; Depressive Disorder; Estrenes; Glucocorticoids; Humans; Hydrocortisone; Male; Middle Aged; Mifepristone

1986