Page last updated: 2024-08-23

mifepristone and Cushing's Syndrome

mifepristone has been researched along with Cushing's Syndrome in 54 studies

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-19908 (14.81)18.7374
1990's9 (16.67)18.2507
2000's12 (22.22)29.6817
2010's20 (37.04)24.3611
2020's5 (9.26)2.80

Authors

AuthorsStudies
Fan, GJ; Tang, XY; Wu, LL; Zeng, HY1
Molitch, ME1
Huang, Y; Su, H; Su, Z; Xu, Z; Zhan, M; Zhao, X; Zheng, R1
Feelders, RA; Hofland, LJ; Houtman, R; Hunt, HJ; Kroon, J; Meijer, OC; Pereira, AM; van den Dungen, ESR; Viho, EMG1
Ault, TA; Braxton, DR; Fong, TL; Marcus, AO; Watson, RA1
Funke, K; Rockey, DC1
Laufgraben, MJ; Morgan, FH1
Canu, L; Corsini, E; Leone, A; Mannelli, M; Montereggi, A; Montereggi, F; Pisaneschi, S1
Colleran, K; Gross, C; Molitch, ME; Purnell, JQ; Wallia, A1
Braunstein, GD; Feldman, D; Gross, C; Katznelson, L; Loriaux, DL; Schteingart, DE1
Davies, H; Fang, M; Hu, Z; Sun, Y1
Badurek, S; Brönneke, HS; Geibel, M; Horn, JM; Koudelka, J; Minichiello, L; Vatanashevanopakorn, C; Wunderlich, CM; Wunderlich, FT1
Kushner, H; Nguyen, D; Williams, G; Yuen, KC1
Kennedy, L1
Banerjee, RR; Feldman, BJ; Katznelson, L; Marina, N1
Cram, D; Fein, HG; Kushner, H; Nguyen, D; Vaughan, TB1
Allolio, B; Bouchard, P; Brue, T; Castinetti, F; Chanson, P; Conte-Devolx, B; Do Cao, C; Fassnacht, M; Hahner, S; Johanssen, S; Morange, I; Ouzounian, S; Picó, A; Terzolo, M; Young, J1
Bailey, MA; Kenyon, CJ; Mullins, JJ1
Pereira, AM; Romijn, JA; Tiemensma, J1
Brue, T; Castinetti, F; Conte-Devolx, B2
de Bruin, C; de Herder, WW; Feelders, RA; Hofland, LJ; Lamberts, SW; Nieman, LK; Sprij-Mooij, DM; van Essen, M; van Koetsveld, PM; Waaijers, AM1
Biller, BM; Tritos, NA1
Biller, BM; Findling, JW; Fleseriu, M; Gross, C; Molitch, ME; Schteingart, DE1
Schteingart, DE1
Carroll, T; Findling, JW1
Grossman, A; Morris, D1
Fujimoto, J1
Ligtenberg, JJ; Meertens, JH; Monteban-Kooistra, WE; Oosterhuis, JK; Tulleken, JE; van den Berg, G; Zijlstra, JG1
Allolio, B; Johanssen, S1
Bilgin, YM; De Herder, WW; Fischer, HR; van der Wiel, HE1
Dang, CN; Trainer, P1
Bamberger, CM; Chrousos, GP1
Crapo, L; Miller, JW1
Dluhy, RG; Solomon, CG1
Kettel, LM1
Cutler, GB; Sartor, O1
Koide, SS1
Ashraf, J; Chilton, D; Kalaitzoglou, G; Licholai, T; New, MI; Newfield, RS; Thompson, EB1
Derendorf, H; Krishnaswami, S; Le-Brun, PP; Schweitzer, DH1
Isacson, C; New, MI; Newfield, RS; Spitz, IM1
Belanoff, J; Chu, JW; Feldman, D; Hoffman, AR; Matthias, DF; Schatzberg, A1
Foeken, K; Lamberts, SW; van der Lely, AJ; van der Mast, RC1
Grünfeld, JP1
Anderson, C; Coles, P1
Bertagna, X1
Barnes, K; Chrousos, GP; Laue, L; Loriaux, DL; Munson, P; Nieman, L; Schaison, G1
Aguercif, M; Beaufrère, B; Chatelain, P; de Parscau, L; François, R; Morel, Y1
Bardin, CW; Chrousos, GP; Cutler, GB; Kellner, C; Loriaux, DL; Merriam, GR; Nieman, LK; Nisula, BC; Spitz, IM1
Brandon, DD; Chrousos, GP; Kawai, S; Laue, L; Loriaux, DL; Nieman, LK; Udelsman, RU1
Brandon, DD; Chrousos, GP; Kawai, S; Loriaux, DL; Nieman, LK; Udelsman, R1
Bertagna, C; Bertagna, X; Girard, F; Husson, JM; Laudat, MH; Luton, JP1
Fraser, HM; Healy, DL1

Reviews

18 review(s) available for mifepristone and Cushing's Syndrome

ArticleYear
Glucocorticoid receptor blockers.
    Pituitary, 2022, Volume: 25, Issue:5

    Topics: Abortifacient Agents; Adrenal Insufficiency; Adrenocorticotropic Hormone; Cushing Syndrome; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP3A; Dexamethasone; Female; Hormone Antagonists; Humans; Hydrocortisone; Mifepristone; Receptors, Glucocorticoid; Receptors, Progesterone

2022
Mifepristone induced liver injury in a patient with Cushing syndrome: a case report and review of the literature.
    Journal of medical case reports, 2023, Feb-03, Volume: 17, Issue:1

    Topics: Abortion, Induced; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Cholestasis; Cushing Syndrome; Female; Humans; Middle Aged; Mifepristone; Pregnancy

2023
Mifepristone for management of Cushing's syndrome.
    Pharmacotherapy, 2013, Volume: 33, Issue:3

    Topics: Cushing Syndrome; Dose-Response Relationship, Drug; Drug Interactions; Hormone Antagonists; Humans; Mifepristone; Receptors, Glucocorticoid

2013
Mifepristone: a potential clinical agent based on its anti-progesterone and anti-glucocorticoid properties.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2014, Volume: 30, Issue:3

    Topics: Abortifacient Agents, Steroidal; Antidepressive Agents; Contraceptives, Oral, Synthetic; Contraceptives, Postcoital, Synthetic; Cushing Syndrome; Endometriosis; Female; Humans; Hyperglycemia; Hypoglycemic Agents; Leiomyoma; Male; Mifepristone; Mood Disorders; Receptors, Glucocorticoid; Receptors, Progesterone

2014
Neuropsychiatric disorders in Cushing's syndrome.
    Neuroendocrinology, 2010, Volume: 92 Suppl 1

    Topics: Cushing Syndrome; Hormone Antagonists; Humans; Mental Disorders; Mifepristone

2010
Advances in medical therapies for Cushing's syndrome.
    Discovery medicine, 2012, Volume: 13, Issue:69

    Topics: Animals; Bexarotene; Cushing Syndrome; Etomidate; Humans; Ketoconazole; Lapatinib; Metyrapone; Mifepristone; Mitotane; Quinazolines; Somatostatin; Tetrahydronaphthalenes

2012
The use of the glucocorticoid receptor antagonist mifepristone in Cushing's syndrome.
    Current opinion in endocrinology, diabetes, and obesity, 2012, Volume: 19, Issue:4

    Topics: Adolescent; Adult; Blood Pressure; Child, Preschool; Cushing Syndrome; Female; Hormone Antagonists; Humans; Hypokalemia; Male; Middle Aged; Mifepristone; Receptors, Glucocorticoid; Young Adult

2012
The medical management of Cushing's syndrome.
    Annals of the New York Academy of Sciences, 2002, Volume: 970

    Topics: Adrenal Glands; Adrenergic Agents; Cushing Syndrome; Dopamine Antagonists; GABA Agonists; Hormone Antagonists; Humans; Mifepristone; Serotonin Antagonists; Somatostatin

2002
[Anti progestins].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64 Suppl 4

    Topics: Abortifacient Agents, Steroidal; Animals; Cushing Syndrome; Endometriosis; Female; Gestrinone; Humans; Meningeal Neoplasms; Meningioma; Menstruation; Mifepristone; Organ Specificity; Pregnancy; Progestins

2006
Mifepristone (RU 486) in Cushing's syndrome.
    European journal of endocrinology, 2007, Volume: 157, Issue:5

    Topics: Animals; Cushing Syndrome; Humans; Mifepristone

2007
The glucocorticoid receptor and RU 486 in man.
    Annals of the New York Academy of Sciences, 1995, Jun-12, Volume: 761

    Topics: Adrenocorticotropic Hormone; Cushing Syndrome; Drug Resistance; Female; Humans; In Vitro Techniques; Male; Mifepristone; Models, Biological; Receptors, Glucocorticoid

1995
The medical treatment of Cushing's syndrome.
    Endocrine reviews, 1993, Volume: 14, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Aminoglutethimide; Animals; Bromocriptine; Cushing Syndrome; Cyproheptadine; Dogs; Horses; Humans; Ketoconazole; Metyrapone; Mifepristone; Mitotane; Octreotide; Palliative Care; Pituitary Gland; Radiography; Valproic Acid

1993
Clinical applications of the antiprogestins.
    Clinical obstetrics and gynecology, 1995, Volume: 38, Issue:4

    Topics: Abortifacient Agents, Steroidal; Breast Neoplasms; Clinical Trials as Topic; Contraceptives, Oral, Synthetic; Cushing Syndrome; Endometriosis; Endometrium; Female; Hormone Antagonists; Humans; Leiomyoma; Meningeal Neoplasms; Meningioma; Menstrual Cycle; Mifepristone; Pregnancy; Pregnancy, Ectopic; Premenstrual Syndrome; Progestins; Uterine Neoplasms

1995
Mifepristone: treatment of Cushing's syndrome.
    Clinical obstetrics and gynecology, 1996, Volume: 39, Issue:2

    Topics: Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Glucocorticoids; Hormone Antagonists; Humans; Male; Mifepristone

1996
Mifepristone. Auxiliary therapeutic use in cancer and related disorders.
    The Journal of reproductive medicine, 1998, Volume: 43, Issue:7

    Topics: Adult; Cushing Syndrome; Endometriosis; Female; Genital Diseases, Female; Genital Neoplasms, Female; Hormone Antagonists; Humans; Mifepristone; Recurrence

1998
Glucocorticoids in blood pressure regulation.
    Hormone research, 1990, Volume: 34, Issue:3-4

    Topics: Animals; Blood Pressure; Cushing Syndrome; Glucocorticoids; Humans; Hypertension; Mifepristone; Rats

1990
[Antiglucocorticoid action of RU 486].
    Annales d'endocrinologie, 1989, Volume: 50, Issue:3

    Topics: Adrenocorticotropic Hormone; Animals; Cushing Syndrome; Drug Administration Schedule; Humans; Hydrocortisone; Mifepristone; Progestins; Rats; Receptors, Glucocorticoid

1989
Glucocorticoids and glucocorticoid antagonists: lessons from RU 486.
    Kidney international. Supplement, 1988, Volume: 26

    Topics: Animals; Cushing Syndrome; Dose-Response Relationship, Drug; Estrenes; Glucocorticoids; Humans; Mifepristone; Receptors, Steroid; Structure-Activity Relationship

1988

Trials

5 trial(s) available for mifepristone and Cushing's Syndrome

ArticleYear
Global clinical response in Cushing's syndrome patients treated with mifepristone.
    Clinical endocrinology, 2014, Volume: 80, Issue:4

    Topics: Adult; Aged; Blood Pressure; Cushing Syndrome; Diabetes Mellitus, Type 2; Female; Glucose Intolerance; Hormone Antagonists; Humans; Hypertension; Male; Middle Aged; Mifepristone; Quality of Life; Receptors, Glucocorticoid

2014
ASSOCIATION BETWEEN MIFEPRISTONE DOSE, EFFICACY, AND TOLERABILITY IN PATIENTS WITH CUSHING SYNDROME.
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2015, Volume: 21, Issue:10

    Topics: Adult; Cushing Syndrome; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Male; Middle Aged; Mifepristone; Receptors, Glucocorticoid; Retrospective Studies; Time Factors; Treatment Outcome

2015
Mifepristone, a glucocorticoid receptor antagonist, produces clinical and metabolic benefits in patients with Cushing's syndrome.
    The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:6

    Topics: Adult; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Composition; Body Weight; Cushing Syndrome; Diabetes Mellitus, Type 2; Female; Glucose Intolerance; Hormone Antagonists; Humans; Hydrocortisone; Hypertension; Male; Middle Aged; Mifepristone; Quality of Life; Quinolines; Receptors, Glucocorticoid; Urea

2012
The antiglucocorticoid and antiprogestin steroid RU 486 suppresses the adrenocorticotropin response to ovine corticotropin releasing hormone in man.
    The Journal of clinical endocrinology and metabolism, 1988, Volume: 66, Issue:2

    Topics: Addison Disease; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Animals; Corticotropin-Releasing Hormone; Cushing Syndrome; Estrenes; Female; Glucocorticoids; Humans; Hydrocortisone; Male; Middle Aged; Mifepristone; Progestins

1988
Pituitary-adrenal response to the antiglucocorticoid action of RU 486 in Cushing's syndrome.
    The Journal of clinical endocrinology and metabolism, 1986, Volume: 63, Issue:3

    Topics: 17-Hydroxycorticosteroids; Adult; beta-Lipotropin; Cushing Syndrome; Estrenes; Female; Glucocorticoids; Humans; Hydrocortisone; Male; Middle Aged; Mifepristone; Pituitary-Adrenal System

1986

Other Studies

31 other study(ies) available for mifepristone and Cushing's Syndrome

ArticleYear
[Mifepristone in the treatment of an elderly patient with adrenocorticotropic hormone-dependent Cushing syndrome].
    Zhonghua nei ke za zhi, 2022, May-01, Volume: 61, Issue:5

    Topics: Adrenocorticotropic Hormone; Aged; Cushing Syndrome; Humans; Mifepristone; Patients

2022
Two cases of infantile-onset primary generalized glucocorticoid hypersensitivity and the effect of mifepristone.
    BMC pediatrics, 2022, 11-08, Volume: 22, Issue:1

    Topics: Adrenocorticotropic Hormone; Child; Cushing Syndrome; Glucocorticoids; Humans; Hypersensitivity; Infant; Male; Mifepristone; Rare Diseases

2022
Peripheral glucocorticoid receptor antagonism by relacorilant with modest HPA axis disinhibition.
    The Journal of endocrinology, 2023, 02-01, Volume: 256, Issue:2

    Topics: Adrenocorticotropic Hormone; Animals; Cushing Syndrome; Dexamethasone; Glucocorticoids; HEK293 Cells; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Leukocytes, Mononuclear; Mice; Mifepristone; Pituitary-Adrenal System; Receptors, Glucocorticoid

2023
Cholestatic Drug-Induced Liver Injury Caused by Mifepristone.
    Hepatology (Baltimore, Md.), 2019, Volume: 69, Issue:6

    Topics: Aged; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Cushing Syndrome; Female; Humans; Mifepristone

2019
[Arterial hypertension and RU-486: a complex case of secondary hypertension].
    Giornale italiano di cardiologia (2006), 2013, Volume: 14, Issue:6

    Topics: Cushing Syndrome; Humans; Hypertension; Male; Middle Aged; Mifepristone

2013
Improvement in insulin sensitivity during mifepristone treatment of Cushing syndrome: early and late effects.
    Diabetes care, 2013, Volume: 36, Issue:9

    Topics: Cushing Syndrome; Glucose Tolerance Test; Hormone Antagonists; Humans; Insulin Resistance; Mifepristone

2013
Ablation of TrkB signalling in CCK neurons results in hypercortisolism and obesity.
    Nature communications, 2014, Mar-12, Volume: 5

    Topics: Animals; Body Composition; Calorimetry, Indirect; Cholecystokinin; Cushing Syndrome; Eating; Female; GABAergic Neurons; Immunoblotting; In Situ Hybridization; Male; Membrane Glycoproteins; Mice; Mifepristone; Obesity; Protein-Tyrosine Kinases

2014
MIFEPRISTONE AND CUSHING SYNDROME: A COMMENTARY.
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2015, Volume: 21, Issue:10

    Topics: Cushing Syndrome; Hormone Antagonists; Humans; Mifepristone

2015
Mifepristone Treatment of Cushing's Syndrome in a Pediatric Patient.
    Pediatrics, 2015, Volume: 136, Issue:5

    Topics: Adolescent; Cushing Syndrome; Female; Humans; Mifepristone

2015
Sustained weight loss in patients treated with mifepristone for Cushing's syndrome: a follow-up analysis of the SEISMIC study and long-term extension.
    BMC endocrine disorders, 2015, Oct-27, Volume: 15

    Topics: Adult; Aged; Cushing Syndrome; Female; Follow-Up Studies; Hormone Antagonists; Humans; Male; Middle Aged; Mifepristone; Prognosis; Receptors, Glucocorticoid; Time Factors; Weight Loss

2015
Merits and pitfalls of mifepristone in Cushing's syndrome.
    European journal of endocrinology, 2009, Volume: 160, Issue:6

    Topics: Adrenal Insufficiency; Adult; Cushing Syndrome; Female; Humans; Hypertension; Hypokalemia; Male; Middle Aged; Mifepristone; Retrospective Studies; Young Adult

2009
Mineralocorticoid and glucocorticoid receptors stimulate epithelial sodium channel activity in a mouse model of Cushing syndrome.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 54, Issue:4

    Topics: Adrenocorticotropic Hormone; Animals; Blood Pressure; Cushing Syndrome; Disease Models, Animal; Epithelial Sodium Channels; Glomerular Filtration Rate; Hormone Antagonists; Loop of Henle; Male; Mice; Mice, Inbred C57BL; Mifepristone; Mineralocorticoid Receptor Antagonists; Receptors, Adrenergic, alpha-1; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Receptors, Vasopressin; Sodium; Sodium-Potassium-Chloride Symporters; Spironolactone

2009
Medical treatment of Cushing's syndrome: glucocorticoid receptor antagonists and mifepristone.
    Neuroendocrinology, 2010, Volume: 92 Suppl 1

    Topics: Cushing Syndrome; Hormone Antagonists; Humans; Mifepristone; Receptors, Glucocorticoid

2010
Mifepristone effects on tumor somatostatin receptor expression in two patients with Cushing's syndrome due to ectopic adrenocorticotropin secretion.
    The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:2

    Topics: ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Adult; Carcinoid Tumor; Cushing Syndrome; Female; Gene Expression Regulation, Neoplastic; Hormone Antagonists; Humans; Lung Neoplasms; Male; Middle Aged; Mifepristone; Receptors, Somatostatin

2012
Drugs in the medical treatment of Cushing's syndrome--an update on mifepristone and pasireotide.
    Expert opinion on emerging drugs, 2012, Volume: 17, Issue:3

    Topics: Clinical Trials as Topic; Cushing Syndrome; Humans; Mifepristone; Receptors, Glucocorticoid; Receptors, Somatostatin; Somatostatin; Treatment Outcome

2012
Mifepristone (Korlym) for Cushing's syndrome.
    The Medical letter on drugs and therapeutics, 2012, Jun-11, Volume: 54, Issue:1392

    Topics: Cushing Syndrome; Drug Approval; Hormone Antagonists; Humans; Mifepristone; United States; United States Food and Drug Administration

2012
The use of mifepristone in the treatment of Cushing's syndrome.
    Drugs of today (Barcelona, Spain : 1998), 2012, Volume: 48, Issue:8

    Topics: Clinical Trials as Topic; Cushing Syndrome; Drug Interactions; Hormone Antagonists; Humans; Mifepristone; Practice Guidelines as Topic

2012
Life-threatening Pneumocystis jiroveci pneumonia following treatment of severe Cushing's syndrome.
    The Netherlands journal of medicine, 2007, Volume: 65, Issue:6

    Topics: Cushing Syndrome; Disease Progression; Fatal Outcome; Female; Humans; Ketoconazole; Middle Aged; Mifepristone; Opportunistic Infections; Pneumocystis carinii; Pneumonia, Pneumocystis; Risk Factors; Spironolactone

2007
Treatment of severe psychosis due to ectopic Cushing's syndrome.
    Journal of endocrinological investigation, 2007, Volume: 30, Issue:9

    Topics: Adrenocorticotropic Hormone; Cushing Syndrome; Drug Therapy, Combination; Etomidate; Female; Hormone Antagonists; Humans; Hydrocortisone; Hypnotics and Sedatives; Lung Neoplasms; Middle Aged; Mifepristone; Psychotic Disorders

2007
Pharmacological management of Cushing's syndrome: an update.
    Arquivos brasileiros de endocrinologia e metabologia, 2007, Volume: 51, Issue:8

    Topics: Cushing Syndrome; Dopamine Antagonists; Hormone Antagonists; Humans; Hypothalamo-Hypophyseal System; Ketoconazole; Metyrapone; Mifepristone; Mitotane; Pituitary-Adrenal System; PPAR gamma; Somatostatin; Steroids

2007
Paraneoplastic endocrine syndromes.
    Current therapy in endocrinology and metabolism, 1994, Volume: 5

    Topics: Acromegaly; Adrenocorticotropic Hormone; Aminoglutethimide; Bromocriptine; Calcitonin; Cushing Syndrome; Diazoxide; Diphosphonates; Estrogens; Fluid Therapy; Hemangiopericytoma; Humans; Hypercalcemia; Hyperthyroidism; Hypoglycemia; Inappropriate ADH Syndrome; Ketoconazole; Mifepristone; Mineralocorticoids; Mitotane; Octreotide; Osteomalacia; Pamidronate; Paraneoplastic Endocrine Syndromes; Phosphorus; Plicamycin; Propylthiouracil; Saline Solution, Hypertonic; Somatostatin; Thyroid Neoplasms

1994
Normocortisolemic Cushing's syndrome initially presenting with increased glucocorticoid receptor numbers.
    The Journal of clinical endocrinology and metabolism, 2000, Volume: 85, Issue:1

    Topics: Adrenocorticotropic Hormone; Child; Cushing Syndrome; Female; Growth; Hormone Antagonists; Human Growth Hormone; Humans; Hydrocortisone; Mifepristone; Organ Size; Phenotype; Receptors, Glucocorticoid

2000
Clinical and pharmacological aspects of accidental triamcinolone acetonide overdosage: a case study.
    The Netherlands journal of medicine, 2000, Volume: 56, Issue:1

    Topics: Anti-Inflammatory Agents; Bursitis; Cushing Syndrome; Drug Overdose; Female; Hormone Antagonists; Humans; Injections, Intra-Articular; Medication Errors; Middle Aged; Mifepristone; Triamcinolone Acetonide

2000
Long-term mifepristone (RU486) therapy resulting in massive benign endometrial hyperplasia.
    Clinical endocrinology, 2001, Volume: 54, Issue:3

    Topics: Adolescent; Contraceptives, Oral, Synthetic; Cushing Syndrome; Endometrial Hyperplasia; Female; Glucocorticoids; Hormone Antagonists; Humans; Magnetic Resonance Imaging; Medroxyprogesterone Acetate; Mifepristone; Osteoporosis; Progesterone; Uterus

2001
Successful long-term treatment of refractory Cushing's disease with high-dose mifepristone (RU 486).
    The Journal of clinical endocrinology and metabolism, 2001, Volume: 86, Issue:8

    Topics: Adrenocorticotropic Hormone; Black or African American; Bone Density; Brain; California; Cholesterol; Cushing Syndrome; Depressive Disorder; Glycated Hemoglobin; Heart Failure; Hormone Antagonists; Humans; Hydrocortisone; Magnetic Resonance Imaging; Male; Mental Status Schedule; Middle Aged; Mifepristone; Osteocalcin; Ventricular Function, Left

2001
Rapid reversal of acute psychosis in the Cushing syndrome with the cortisol-receptor antagonist mifepristone (RU 486).
    Annals of internal medicine, 1991, Jan-15, Volume: 114, Issue:2

    Topics: Acute Disease; Adrenal Gland Neoplasms; Adult; Cushing Syndrome; Female; Glucocorticoids; Humans; Male; Mifepristone; Psychotic Disorders

1991
RU-486. Drug debate expands.
    Nature, 1990, Nov-29, Volume: 348, Issue:6300

    Topics: Biomedical Research; Breast Neoplasms; Cushing Syndrome; Federal Government; Government Regulation; Humans; Internationality; Mifepristone; Research; Risk Assessment; United States; United States Food and Drug Administration

1990
RU 486 administration in a child with Cushing's syndrome.
    Lancet (London, England), 1987, Jul-25, Volume: 2, Issue:8552

    Topics: Administration, Oral; Child, Preschool; Cushing Syndrome; Estrenes; Female; Glucocorticoids; Humans; Mifepristone

1987
Successful treatment of Cushing's syndrome with the glucocorticoid antagonist RU 486.
    The Journal of clinical endocrinology and metabolism, 1985, Volume: 61, Issue:3

    Topics: Adrenocorticotropic Hormone; Adult; Blood Glucose; Carrier Proteins; Cushing Syndrome; Estrenes; Humans; Hydrocortisone; Luteinizing Hormone; Male; Mifepristone; Steroids; Testosterone

1985
Pharmacokinetic properties of the antiglucocorticoid and antiprogesterone steroid RU 486 in man.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:2

    Topics: Adult; Animals; Cushing Syndrome; Dexamethasone; Estrenes; Female; Half-Life; Humans; Kinetics; Male; Middle Aged; Mifepristone; Progesterone; Promegestone; Radioligand Assay; Rats; Receptors, Progesterone; Thymus Gland; Uterus

1987
The antiprogesterones are coming: menses induction, abortion, and labour?
    British medical journal (Clinical research ed.), 1985, Feb-23, Volume: 290, Issue:6468

    Topics: Abortifacient Agents, Steroidal; Abortion, Induced; Animals; Cushing Syndrome; Estrenes; Female; Humans; Labor, Induced; Menstruation; Mifepristone; Pregnancy; Progesterone; Rabbits

1985