Page last updated: 2024-08-23

mifepristone and Cancer of Endometrium

mifepristone has been researched along with Cancer of Endometrium in 31 studies

Research

Studies (31)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	9 (29.03)	18.2507
2000's	15 (48.39)	29.6817
2010's	4 (12.90)	24.3611
2020's	3 (9.68)	2.80

Authors

Authors	Studies
Abd Jamil, AH; Chung, I; Mat Adenan, NA; Omar, IS	1
Chung, I; Godoy, A; Gunasagran, Y; Mat Adenan, NA; Omar, IS; Teo, IH	1
Hong, L; Qian, M; Wu, Q; Zhang, L	1
Metsis, M; Salumets, A; Simm, J; Suhorutshenko, M; Tamm-Rosenstein, K	1
Li, MJ; Lu, ZZ; Yan, L; Zhang, H; Zhang, XH; Zhao, XX	1
Grønaas, H; Moe, BT; Paulssen, RH; Ørbo, A	1
Moe, BG; Orbo, A; Sager, G; Vereide, AB	1
Jaeger, R; Moe, BT; Orbo, A; Sager, G; Vereide, AB	1
Amazit, L; Bellance, C; Guiochon-Mantel, A; Khan, JA; Lombès, M; Loosfelt, H	1
Bouchard, P	1
Chao, V; Dreher, E; Mueller, MD; Pritts, EA; Taylor, RN; Vigne, JL	1
Lan, SM; Li, CZ; Liu, Y; Wang, JY; Wen, ZQ	1
Archer, DF; Mirkin, S	1
Chen, CL; Liao, QP; Lu, Y; Yu, L	2
Amezcua, CA; Felix, JC; Jain, JK; Li, A; Minoo, P	1
Bamberger, AM; Briese, J; Erdmann, I; Götze, J; Nollau, P; Schulte, HM; Wagener, C	1
Brown, J; Burke, T; Gaikwad, A; Navo, MA; Ramondetta, LM; Smith, JA	1
Gravanis, A; Makrigiannakis, A; Margioris, AN; Stournaras, C	1
Falany, CN; Falany, JL	1
Bamberger, AM; Bamberger, CM; Gellersen, B; Schulte, HM	1
Chrousos, GP; Gravanis, A; Makrigiannakis, A; Margioris, AN; Stournaras, C; Zoumakis, E	1
Castelbaum, AJ; Chwalisz, K; Ilesanmi, AO; Lessey, BA; Satyaswaroop, PG; Somkuti, SG; Yuan, L	1
Van Look, PF; von Hertzen, H	1
Gurpide, E; Markiewicz, L	1
Hyder, SM; Murthy, L; Stancel, GM	1
Levental, M; Martineau, PA	1
Arnulfo, A; Baj, G; Boldorini, R; Malavasi, F; Nicosia, G; Surico, N; Villa, L	1
Kovács, L; Zalányi, S	1
Arnold, JT; Kaufman, DG; Lessey, BA; Seppälä, M	1
Distler, W; Vering, A	1

Reviews

4 review(s) available for mifepristone and Cancer of Endometrium

Article	Year
Current and future medical treatments for menometrorrhagia during the premenopause. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2011, Volume: 27 Suppl 1 Topics: Adolescent; Adult; Contraceptives, Oral; Endometrial Neoplasms; Female; Gonadotropin-Releasing Hormone; Humans; Leiomyoma; Levonorgestrel; Menorrhagia; Metrorrhagia; Mifepristone; Norpregnadienes; Polyps; Premenopause; Progestins; Randomized Controlled Trials as Topic; Receptors, Progesterone; Uterine Neoplasms	2011
Clinical uses of antiprogestogens. Human reproduction update, 1995, Volume: 1, Issue:1 Topics: Abortion, Induced; Antineoplastic Agents; Breast Neoplasms; Contraception; Contraceptives, Oral, Synthetic; Endometrial Neoplasms; Endometriosis; Estrenes; Female; Gonanes; Humans; Labor, Induced; Mifepristone; Pregnancy; Pregnancy Trimester, Second; Progestins; Prostaglandins; Receptors, Progesterone	1995
[Effect of antigestagens on human reproduction]. Orvosi hetilap, 2001, Apr-22, Volume: 142, Issue:16 Topics: Abortifacient Agents, Steroidal; Abortion, Spontaneous; Abortion, Therapeutic; Contraceptives, Oral, Hormonal; Endometrial Neoplasms; Endometriosis; Female; Hormone Antagonists; Humans; Labor, Induced; Mifepristone; Pregnancy; Progesterone	2001
[Progesterone antagonists--pharmacology and perspectives of use]. Der Gynakologe, 1992, Volume: 25, Issue:4 Topics: Abortion, Induced; Animals; Breast Neoplasms; Endometrial Neoplasms; Female; Humans; Infant, Newborn; Luteal Phase; Mifepristone; Neoplasms, Hormone-Dependent; Pregnancy; Progesterone; Tumor Cells, Cultured	1992

Trials

1 trial(s) available for mifepristone and Cancer of Endometrium

Article	Year
[Study on the treatment of high dose mifepristone and progesterone in endometrial carcinoma]. Zhonghua fu chan ke za zhi, 2003, Volume: 38, Issue:9 Topics: Adult; Aged; Drug Therapy, Combination; Endometrial Neoplasms; Female; Glycoproteins; Humans; Hyaluronan Receptors; Middle Aged; Mifepristone; Progesterone; Proliferating Cell Nuclear Antigen; Receptors, Estrogen; Receptors, Progesterone	2003

Other Studies

26 other study(ies) available for mifepristone and Cancer of Endometrium

Article	Year
MPA alters metabolic phenotype of endometrial cancer-associated fibroblasts from obese women via IRS2 signaling. PloS one, 2022, Volume: 17, Issue:7 Topics: Acetates; Cancer-Associated Fibroblasts; Endometrial Neoplasms; Female; Glucose; Humans; Insulin Receptor Substrate Proteins; Medroxyprogesterone Acetate; Mifepristone; Neoplasm Recurrence, Local; Obesity; Phenotype; Progesterone; Receptors, Progesterone; RNA, Messenger	2022
Aberrant upregulation of CDK1 contributes to medroxyprogesterone acetate (MPA) resistance in cancer-associated fibroblasts of the endometrium. Biochemical and biophysical research communications, 2022, 11-05, Volume: 628 Topics: Cancer-Associated Fibroblasts; CDC2 Protein Kinase; Drug Resistance, Neoplasm; Endometrial Neoplasms; Endometrium; Female; Humans; Luciferases; Medroxyprogesterone Acetate; Mifepristone; Neoplasms; Receptors, Progesterone; RNA, Messenger; Up-Regulation	2022
First case report of acute generalized exanthematous pustulosis (AGEP) caused by mifepristone. Contact dermatitis, 2020, Volume: 82, Issue:3 Topics: Acute Generalized Exanthematous Pustulosis; Adult; Anti-Inflammatory Agents; Dermatologic Agents; Dexamethasone; Endometrial Neoplasms; Female; Hormone Antagonists; Humans; Hysteroscopy; Mifepristone; Polyps; Progestins	2020
Changes in the transcriptome of the human endometrial Ishikawa cancer cell line induced by estrogen, progesterone, tamoxifen, and mifepristone (RU486) as detected by RNA-sequencing. PloS one, 2013, Volume: 8, Issue:7 Topics: Cell Line, Tumor; Endometrial Neoplasms; Estrogens; Female; Gene Expression Profiling; GTP-Binding Proteins; Humans; Membrane Proteins; Mifepristone; Mitochondrial Proteins; Neoplasm Proteins; Progesterone; Receptors for Activated C Kinase; Receptors, Cell Surface; Tamoxifen; Transcriptome	2013
[Mifepristone inhibites the migration of endometrial cancer cells through regulating H19 methylation]. Zhonghua zhong liu za zhi [Chinese journal of oncology], 2016, Jun-23, Volume: 38, Issue:6 Topics: Antigens, CD; Cadherins; Carcinoma; Cell Line, Tumor; Cell Movement; DNA Methylation; Down-Regulation; Endometrial Neoplasms; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; HMGA2 Protein; Humans; Mifepristone; Promoter Regions, Genetic; RNA, Long Noncoding; RNA, Messenger; Up-Regulation; Vimentin	2016
Early effects of high concentrations of progesterone and mifepristone A gene expression study of endometrial cancer cells (Ishikawa). The Journal of steroid biochemistry and molecular biology, 2009, Volume: 113, Issue:1-2 Topics: Cell Line, Tumor; Down-Regulation; Endometrial Neoplasms; Epidermal Growth Factor; Female; Gene Expression Regulation, Neoplastic; Humans; Mifepristone; Progesterone; Progestins; Receptors, Progesterone; Up-Regulation	2009
High concentrations of progesterone and mifepristone mutually reinforce cell cycle retardation and induction of apoptosis. Anticancer research, 2009, Volume: 29, Issue:4 Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle; Cell Line, Tumor; Contraceptives, Oral, Synthetic; Drug Synergism; Endometrial Neoplasms; Female; Flow Cytometry; Humans; Mifepristone; Progesterone; Progestins	2009
Levonorgestrel, medroxyprogesterone and progesterone cause a concentration-dependent reduction in endometrial cancer (Ishikawa) cell density, and high concentrations of progesterone and mifepristone act in synergy. Anticancer research, 2009, Volume: 29, Issue:4 Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Contraceptives, Oral, Synthetic; Dose-Response Relationship, Drug; Drug Synergism; Endometrial Neoplasms; Female; Humans; Levonorgestrel; Medroxyprogesterone; Mifepristone; Progesterone; Progestins; Receptors, Progesterone	2009
p38 and p42/44 MAPKs differentially regulate progesterone receptor A and B isoform stabilization. Molecular endocrinology (Baltimore, Md.), 2011, Volume: 25, Issue:10 Topics: Breast Neoplasms; Cell Line, Tumor; Endometrial Neoplasms; Female; Gonanes; Humans; Ligands; MAP Kinase Kinase Kinase 1; Mifepristone; Mitogen-Activated Protein Kinase 1; Models, Biological; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Phosphoserine; Promegestone; Proteasome Endopeptidase Complex; Protein Isoforms; Protein Stability; Receptors, Progesterone; Transcription, Genetic	2011
Progestins activate vascular endothelial growth factor gene transcription in endometrial adenocarcinoma cells. Fertility and sterility, 2003, Volume: 79, Issue:2 Topics: Adenocarcinoma; Endometrial Neoplasms; Endothelial Growth Factors; Female; Gene Expression Regulation, Neoplastic; Humans; Intercellular Signaling Peptides and Proteins; Lymphokines; Medroxyprogesterone; Mifepristone; Promegestone; Receptors, Progesterone; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	2003
Effects of mifepristone on vascular endothelial growth factor and thrombospondin-1 mRNA in Ishikawa cells: implication for the endometrial effects of mifepristone. Contraception, 2004, Volume: 70, Issue:4 Topics: Adenocarcinoma; Cell Line; Contraceptives, Oral, Synthetic; Dose-Response Relationship, Drug; Endometrial Neoplasms; Endometrium; Epithelial Cells; Estradiol; Female; Gene Expression; Hormone Antagonists; Humans; Mifepristone; Progesterone; RNA, Messenger; Thrombospondin 1; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A	2004
[Effects of estrogen, progestin and mifepristone on endometrial carcinoma cell lines]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2005, Jun-18, Volume: 37, Issue:3 Topics: Cell Line, Tumor; Cell Proliferation; Endometrial Neoplasms; Estradiol; Female; Humans; Mifepristone; Progesterone; Uterine Neoplasms	2005
Effect of mifepristone on proliferation and apoptosis of Ishikawa endometrial adenocarcinoma cells. Fertility and sterility, 2005, Volume: 84, Issue:1 Topics: Adenocarcinoma; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Endometrial Neoplasms; Female; Humans; Mifepristone	2005
Stimulation of CEACAM1 expression by 12-O-tetradecanoylphorbol-13-acetate (TPA) and calcium ionophore A23187 in endometrial carcinoma cells. Carcinogenesis, 2006, Volume: 27, Issue:3 Topics: Anti-Bacterial Agents; Antigens, CD; Calcimycin; Carcinoma; Cell Adhesion Molecules; Endometrial Neoplasms; Estradiol; Female; Hormone Antagonists; Humans; Interferon-gamma; Medroxyprogesterone Acetate; Mifepristone; Phorbol Esters; Protein Kinase C; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha	2006
[Functional study of progesterone receptor isoforms in endometrial cancer cell lines]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2006, Oct-18, Volume: 38, Issue:5 Topics: Adenocarcinoma; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Endometrial Neoplasms; Estradiol; Female; Humans; Mifepristone; Oligodeoxyribonucleotides, Antisense; Promegestone; Receptors, Progesterone; Transfection	2006
In vitro evaluation of the growth inhibition and apoptosis effect of mifepristone (RU486) in human Ishikawa and HEC1A endometrial cancer cell lines. Cancer chemotherapy and pharmacology, 2008, Volume: 62, Issue:3 Topics: Apoptosis; Cell Line, Tumor; Cyclooxygenase 2; Endometrial Neoplasms; Female; Flow Cytometry; Hormone Antagonists; Humans; Immunohistochemistry; Inhibitory Concentration 50; Mifepristone; Proto-Oncogene Proteins c-bcl-2; Receptors, Steroid; Tumor Suppressor Protein p53	2008
Interaction between steroid hormones and endometrial opioids. Annals of the New York Academy of Sciences, 1994, Sep-30, Volume: 734 Topics: Adenocarcinoma; Animals; beta-Endorphin; Blotting, Northern; Dexamethasone; Dynorphins; Endometrial Neoplasms; Estradiol; Female; Hormones; Humans; Male; Mifepristone; Potassium Chloride; Pro-Opiomelanocortin; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tamoxifen; Tumor Cells, Cultured	1994
Regulation of estrogen sulfotransferase in human endometrial adenocarcinoma cells by progesterone. Endocrinology, 1996, Volume: 137, Issue:4 Topics: Adenocarcinoma; Endometrial Neoplasms; Estrone; Female; Humans; Mifepristone; Progesterone; RNA, Messenger; Sulfates; Sulfotransferases; Tumor Cells, Cultured	1996
Modulation of AP-1 activity by the human progesterone receptor in endometrial adenocarcinoma cells. Proceedings of the National Academy of Sciences of the United States of America, 1996, Jun-11, Volume: 93, Issue:12 Topics: Adenocarcinoma; Animals; Base Sequence; Cell Line; Endometrial Neoplasms; Female; Haplorhini; Hormone Antagonists; Humans; Medroxyprogesterone Acetate; Mifepristone; Molecular Sequence Data; Promoter Regions, Genetic; Receptors, Estrogen; Receptors, Progesterone; Transcription Factor AP-1; Transfection; Tumor Cells, Cultured	1996
Regulation of the promoter of the human corticotropin-releasing hormone gene in transfected human endometrial cells. Neuroendocrinology, 1996, Volume: 64, Issue:2 Topics: Adenocarcinoma; Corticotropin-Releasing Hormone; Cyclic AMP; Dexamethasone; Dinoprostone; Endometrial Neoplasms; Endometrium; Epidermal Growth Factor; Estradiol; Female; Gene Expression Regulation; Humans; Indomethacin; Luciferases; Mifepristone; Promoter Regions, Genetic; Recombinant Fusion Proteins; Transcriptional Activation; Transfection; Tumor Cells, Cultured	1996
Characterization of the functional progesterone receptor in an endometrial adenocarcinoma cell line (Ishikawa): progesterone-induced expression of the alpha1 integrin. The Journal of steroid biochemistry and molecular biology, 1996, Volume: 59, Issue:1 Topics: Adenocarcinoma; Endometrial Neoplasms; Estradiol; Female; Gene Expression Regulation, Neoplastic; Hormone Antagonists; Humans; Integrin alpha1beta1; Integrins; Mifepristone; Neoplasm Proteins; Progesterone; Protein Biosynthesis; Receptors, Progesterone; RNA, Messenger; RNA, Neoplasm; Transcription, Genetic; Tumor Cells, Cultured	1996
Estrogenic and progestagenic activities of physiologic and synthetic androgens, as measured by in vitro bioassays. Methods and findings in experimental and clinical pharmacology, 1997, Volume: 19, Issue:4 Topics: Adenocarcinoma; Alkaline Phosphatase; Androgen Antagonists; Androgens; Breast Neoplasms; Cyproterone Acetate; Endometrial Neoplasms; Estradiol; Estrogen Antagonists; Female; Flutamide; Gonanes; Humans; Mifepristone; Polyunsaturated Alkamides; Progestins; Tamoxifen; Testosterone; Testosterone Congeners; Tumor Cells, Cultured	1997
Progestin regulation of vascular endothelial growth factor in human breast cancer cells. Cancer research, 1998, Feb-01, Volume: 58, Issue:3 Topics: Breast Neoplasms; Endometrial Neoplasms; Endothelial Growth Factors; Female; Gene Expression Regulation, Neoplastic; Humans; Lymphokines; Medroxyprogesterone Acetate; Megestrol Acetate; Mifepristone; Neoplasm Proteins; Neovascularization, Pathologic; Norethindrone; Norethynodrel; Norgestrel; Progesterone; Progestins; Receptors, Progesterone; Stimulation, Chemical; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	1998
Large endometrial polyp in a patient on long-term mifepristone therapy. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2000, Volume: 19, Issue:7 Topics: Endometrial Neoplasms; Female; Hormone Antagonists; Humans; Meningeal Neoplasms; Meningioma; Middle Aged; Mifepristone; Polyps; Progesterone; Ultrasonography	2000
Hormonal modulation of GM-CSF receptor alpha-chain in in vitro models of endometrial cancer. European journal of gynaecological oncology, 2000, Volume: 21, Issue:3 Topics: Dose-Response Relationship, Drug; Down-Regulation; Endometrial Neoplasms; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Mifepristone; Progesterone; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Tumor Cells, Cultured	2000
Effect of normal endometrial stroma on growth and differentiation in Ishikawa endometrial adenocarcinoma cells. Cancer research, 2002, Jan-01, Volume: 62, Issue:1 Topics: Adenocarcinoma; Basement Membrane; Cell Communication; Cell Differentiation; Cell Division; Coculture Techniques; Collagen; Culture Media; Drug Combinations; Endometrial Neoplasms; Endometrium; Estrogens; Female; Glycodelin; Glycoproteins; Humans; Laminin; Mifepristone; Pregnancy Proteins; Progesterone; Proteoglycans; Stromal Cells; Tissue Extracts	2002