Page last updated: 2024-08-23

mifepristone and Body Weight

mifepristone has been researched along with Body Weight in 66 studies

Research

Studies (66)

TimeframeStudies, this research(%)All Research%
pre-19905 (7.58)18.7374
1990's26 (39.39)18.2507
2000's16 (24.24)29.6817
2010's19 (28.79)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bethea, JR; Jiang, J; Norden, DM1
Berry, JN; Butler, TR; Prendergast, MA; Reynolds, AR; Sharrett-Field, L1
Breivik, T; Gjermo, P; Gundersen, Y; Opstad, PK1
Kagami, K; Nishigori, H1
Anton, F; Hanesch, U; Le Coz, GM1
Beaudry, JL; Belanoff, JK; Dunford, EC; Hunt, H; Riddell, MC; Teich, T; Zaharieva, D1
Chijiwa, T; Lkhagvasuren, B; Oka, T; Sudo, N; Yoshihara, K1
Belanoff, JK; Boon, MR; Hunt, H; Meijer, OC; Pereira, AM; Peschier-van der Put, E; Rensen, PC; van Beek, L; van den Heuvel, JK; van Dijk, KW; van Harmelen, V; van Hengel, I1
Beaudry, JL; Belanoff, JK; Dunford, EC; Hunt, H; Pivovarov, JA; Porras, DP; Riddell, MC; Teich, T1
Bechtold, AG; Hochhaus, G; Patel, G; Scheuer, DA1
Flatt, PR; Frizzell, N; Gault, VA; McKillop, AM; Taylor, AI1
Chen, H; Chen, Z; Dai, W; Guan, M; Lane, NE; Pham, A; Shahnazari, M; Yao, W1
Cano, R; Cejas, H; Correa, SG; Porporatto, C; Rodríguez-Galán, MC; Sotomayor, CE1
Biller, BM; Findling, JW; Fleseriu, M; Gross, C; Molitch, ME; Schteingart, DE1
Kmiec, Z; Stelmanska, E; Swierczynski, J1
Bradley, AJ; Feay, N; Geiser, F; McAllan, BM1
Belanoff, JK; Champagne, DL; Claessens, SE; de Kloet, ER; Kanatsou, S; Lucassen, PJ1
Hu, P; Joëls, M; Lucassen, PJ; Oomen, C; van Dam, AM; Wester, J; Zhou, JN1
Hong, L; Schmidt, T; Stanford, C; Wei, N; Yu, Y1
Sutton, RL; Taylor, AN; Tio, DL1
Hsieh, TH; Kuo, YM; Lin, CH; Lin, YC; Lin, YJ; Sze, CI1
Arias, J; Artaza, J; Bhasin, S; Gonzalez-Cadavid, N; Ma, K; Mahabadi, V; Mallidis, C; Salehian, B1
Archambault, EZ; Boatright, NK; Fray, J; Hicks, E; Kirchain, S; McCune, SA; Sharkey, LC; Simpson, GI1
Mondry, A1
Barja-Fidalgo, TC; Barreto, EO; Bertho, AL; Carvalho, VF; Cordeiro, RS; e Silva, PM; Martins, MA; Oliveira, MS1
Beebe, KL; Belanoff, JK; Blasey, C; Block, T; Debattista, C1
Kadotomi, Y; Kang, Z; Li, X; Song, C1
Joëls, M; van Gemert, NG1
Glavas, MM; Weinberg, J; Yu, WK1
Joëls, M; Karst, H1
Bruch, D; Harb, G; Kieffer, TJ; Korbutt, GS; Lam, AW; Lam, NT; Oosman, SN; Unniappan, S; Webber, T; Zhang, QX1
Baer, DJ; Castonguay, TW; Trocki, O1
Challet, E; Cherel, Y; le Maho, Y; Malan, A; Robin, JP1
Bardin, CW; Kaplan-Kraicer, R; Shalgi, R1
Engel, JA; Eriksson, CJ; Fahlke, C; Hansen, S; Hård, E1
Brandt, HA; Chrousos, GP; DeBellis, MD; Demitrack, MA; Gold, PW; Kalogeras, KT; Kling, MA; Listwak, SJ; Whitfield, HJ1
Borysewicz, R; Fu, CL; Lee, PC; Werlin, SL1
Duncan, GS; Flower, RJ; Peers, SH1
Baram, TZ; Masters, JN; Yi, SJ1
Heikinheimo, O; Spitz, IM; Wade, CE1
Hunt, A; Kelly, FJ; Langley, SC; Postle, AD; Rickett, GW; York, DA1
Bell, SC; Sadek, S1
Dagnault, A; Deshaies, Y; Richard, D1
Busch, BL; Curry, DL; Dallman, MF; Havel, PJ; Johnson, PR; Stern, JS1
Nedvídková, J; Schreiber, V; Stárka, L1
Bertagna, X1
Burns, SJ; Dryden, S; Frankish, HM; Williams, G1
Daly, JM; Evoy, D; Fujita, J; Mackrell, P; McCarter, MD; Naama, HA; Rivadeneira, DE1
Flynn, NE; Knabe, DA; Wu, G1
Aldaghlas, TA; Holleran, AL; Kelleher, JK; Lindenthal, B; Ruan, B; Schroepfer, GJ; Wilson, WK1
Buntin, JD; Koch, KA; Wingfield, JC1
Cao, T; O'Malley, BW; Roop, DR; Tsai, SY; Wang, XJ1
Kalimi, M; Opoku, J1
Abe, T; Chambers, TJ; Chow, JW; Lean, JM1
Barfield, RJ; Pleim, ET; Weinstein, MA1
Baumgarten, R; van der Schoot, P1
Breban, M; Fournier, C; Gougerot-Pocidalo, MA; Muffat-Joly, M; Pocidalo, JJ1
Muskiet, FA; Slappendel, EJ; van der Schoot, P; Zeegers, TA1
Dubuc, PU; Peterson, CM1
Slappendel, EJ; Uilenbroek, JT; van der Schoot, P1
Langley, SC; York, DA1
Kalimi, M1
Bardin, CW; Heikinheimo, O; Krieger, DT; Lahteenmaki, P; Spitz, IM; Wade, CE1
Bons, EG; Lamberts, SW; Uitterlinden, P; Verleun, T1
Bakker, GH; de Jong, FH; Henkelman, MS; Klijn, JG; Lamberts, SW; Setyono-Han, B; van der Schoot, P1
Konagaya, M; Max, SR1

Trials

3 trial(s) available for mifepristone and Body Weight

ArticleYear
Mifepristone, a glucocorticoid receptor antagonist, produces clinical and metabolic benefits in patients with Cushing's syndrome.
    The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:6

    Topics: Adult; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Composition; Body Weight; Cushing Syndrome; Diabetes Mellitus, Type 2; Female; Glucose Intolerance; Hormone Antagonists; Humans; Hydrocortisone; Hypertension; Male; Middle Aged; Mifepristone; Quality of Life; Quinolines; Receptors, Glucocorticoid; Urea

2012
Effects of the glucocorticoid antagonist RU 486 on pituitary-adrenal function in patients with anorexia nervosa and healthy volunteers: enhancement of plasma ACTH and cortisol secretion in underweight patients.
    Neuroendocrinology, 1993, Volume: 57, Issue:6

    Topics: Adrenocorticotropic Hormone; Adult; Anorexia Nervosa; Body Weight; Double-Blind Method; Female; Glucocorticoids; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Mifepristone; Pituitary-Adrenal System; Psychiatric Status Rating Scales

1993
Pituitary-adrenal response to RU 486 in man.
    Psychoneuroendocrinology, 1997, Volume: 22 Suppl 1

    Topics: Blood Pressure; Body Temperature; Body Weight; Cross-Over Studies; Double-Blind Method; Heart Rate; Hormone Antagonists; Humans; Hydrocortisone; Male; Mifepristone; Pituitary-Adrenal System

1997

Other Studies

63 other study(ies) available for mifepristone and Body Weight

ArticleYear
Impaired CD8 T cell antiviral immunity following acute spinal cord injury.
    Journal of neuroinflammation, 2018, May-17, Volume: 15, Issue:1

    Topics: Acute Disease; Animals; Antiviral Agents; Body Weight; CD8-Positive T-Lymphocytes; Cells, Cultured; Cytokines; Disease Models, Animal; Female; Flow Cytometry; Hemagglutinin Glycoproteins, Influenza Virus; Hormone Antagonists; Inflammation; Lung; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mifepristone; Orthomyxoviridae Infections; Spinal Cord Injuries; Spleen

2018
Mifepristone pretreatment reduces ethanol withdrawal severity in vivo.
    Alcoholism, clinical and experimental research, 2013, Volume: 37, Issue:8

    Topics: Alcoholism; Animals; Body Weight; Corticosterone; Drug Evaluation, Preclinical; Eating; Ethanol; Hormone Antagonists; Male; Mifepristone; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Severity of Illness Index; Substance Withdrawal Syndrome

2013
Chronic treatment with the glucocorticoid receptor antagonist RU486 inhibits diabetes-induced enhancement of experimental periodontitis.
    Journal of periodontal research, 2014, Volume: 49, Issue:1

    Topics: Alveolar Bone Loss; Animals; Blood Glucose; Body Weight; Corticosterone; Diabetes Mellitus, Experimental; Drug Implants; Escherichia coli; Hormone Antagonists; Hypothalamo-Hypophyseal System; Interleukin-10; Lipopolysaccharides; Mifepristone; Periodontitis; Pituitary-Adrenal System; Placebos; Radiography; Random Allocation; Rats; Receptors, Glucocorticoid; Streptozocin; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha

2014
Impaired imprinting and social behaviors in chicks exposed to mifepristone, a glucocorticoid receptor antagonist, during the final week of embryogenesis.
    Behavioural brain research, 2014, Mar-15, Volume: 261

    Topics: Aggression; Animals; Body Weight; Brain; Chick Embryo; Female; Imprinting, Psychological; Learning Disabilities; Mifepristone; Organ Size; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, Glucocorticoid; Social Behavior Disorders; Vocalization, Animal

2014
Glucocorticoid-mediated enhancement of glutamatergic transmission may outweigh anti-inflammatory effects under conditions of neuropathic pain.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Body Weight; Cytokines; Disease Models, Animal; Gene Expression; Glucocorticoids; Glutamic Acid; Male; Mifepristone; Neuralgia; Pain Threshold; Peripheral Nerve Injuries; Rats; Receptors, Glucocorticoid; Synaptic Transmission

2014
Effects of selective and non-selective glucocorticoid receptor II antagonists on rapid-onset diabetes in young rats.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Animals; Blood Glucose; Body Weight; Corticosterone; Diabetes Mellitus, Experimental; Diet, High-Fat; Hormone Antagonists; Insulin; Insulin Resistance; Male; Mifepristone; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Small Molecule Libraries

2014
Prior chronic stress induces persistent polyI:C-induced allodynia and depressive-like behavior in rats: Possible involvement of glucocorticoids and microglia.
    Physiology & behavior, 2015, Aug-01, Volume: 147

    Topics: Animals; Body Weight; Depression; Disease Models, Animal; Drug Administration Routes; Eating; Fever; Hormone Antagonists; Hyperalgesia; Interferon Inducers; Male; Mifepristone; Minocycline; Pain Management; Poly I-C; Rats; Rats, Long-Evans; Rats, Wistar; Stress, Psychological; Swimming; Time Factors

2015
Identification of a selective glucocorticoid receptor modulator that prevents both diet-induced obesity and inflammation.
    British journal of pharmacology, 2016, Volume: 173, Issue:11

    Topics: Animals; Body Weight; Diet, High-Fat; Inflammation; Male; Mice; Mice, Inbred C57BL; Mifepristone; Obesity; RAW 264.7 Cells; Receptors, Glucocorticoid

2016
Glucocorticoid antagonism limits adiposity rebound and glucose intolerance in young male rats following the cessation of daily exercise and caloric restriction.
    American journal of physiology. Endocrinology and metabolism, 2016, 07-01, Volume: 311, Issue:1

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adiposity; Animals; Blood Glucose; Blotting, Western; Body Weight; Caloric Restriction; Gluconeogenesis; Glucose Intolerance; Glucose Tolerance Test; Glycogen; Glycogenolysis; Hormone Antagonists; Insulin; Insulin Resistance; Intra-Abdominal Fat; Lipolysis; Liver; Male; Mifepristone; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid

2016
Chronic blockade of hindbrain glucocorticoid receptors reduces blood pressure responses to novel stress and attenuates adaptation to repeated stress.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 296, Issue:5

    Topics: Adaptation, Physiological; Animals; Blood Pressure; Body Weight; Corticosterone; Disease Models, Animal; Heart Rate; Hormone Antagonists; Hypertension; Male; Mifepristone; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Rhombencephalon; Stress, Physiological

2009
Effect of RU486 on hepatic and adipocyte gene expression improves diabetes control in obesity-type 2 diabetes.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2009, Volume: 41, Issue:12

    Topics: Adipocytes; Adipose Tissue, White; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Drug Administration Schedule; Epididymis; Fasting; Feeding Behavior; Gene Expression Regulation; Glucose Tolerance Test; Insulin; Liver; Male; Mice; Mice, Obese; Mifepristone; Obesity; Pancreas; RNA, Messenger; Triglycerides

2009
Inhibition of the progesterone nuclear receptor during the bone linear growth phase increases peak bone mass in female mice.
    PloS one, 2010, Jul-01, Volume: 5, Issue:7

    Topics: Animals; Apoptosis; Body Weight; Bone Density; Bone Development; Bone Resorption; Cell Differentiation; Cells, Cultured; Female; Hormone Antagonists; Male; Mice; Mice, Knockout; Mifepristone; Osteoblasts; Osteogenesis; Receptors, Progesterone; Sex Factors

2010
Immune-metabolic balance in stressed rats during Candida albicans infection.
    Stress (Amsterdam, Netherlands), 2010, Volume: 13, Issue:5

    Topics: Animals; Blood Glucose; Body Weight; Candidiasis; Eating; Female; Food Deprivation; Glucocorticoids; Hormone Antagonists; Leptin; Liver; Liver Glycogen; Mifepristone; Rats; Rats, Wistar; Stress, Psychological; Tumor Necrosis Factor-alpha

2010
The gender- and fat depot-specific regulation of leptin, resistin and adiponectin genes expression by progesterone in rat.
    The Journal of steroid biochemistry and molecular biology, 2012, Volume: 132, Issue:1-2

    Topics: Adiponectin; Adipose Tissue, White; Animals; Body Weight; Female; Gene Expression Regulation; Hormone Antagonists; Leptin; Male; Mifepristone; Progesterone; Rats; Receptors, Progesterone; Resistin; RNA, Messenger; Sex Characteristics

2012
The influence of reproductive hormones on the torpor patterns of the marsupial Sminthopsis macroura: bet-hedging in an unpredictable environment.
    General and comparative endocrinology, 2012, Nov-01, Volume: 179, Issue:2

    Topics: Adaptation, Physiological; Animals; Basal Metabolism; Body Temperature; Body Temperature Regulation; Body Weight; Circadian Rhythm; Estrogens; Female; Flutamide; Hormone Antagonists; Male; Marsupialia; Mifepristone; Photoperiod; Progesterone; Reproduction; Tamoxifen; Testosterone

2012
Acute effects of neonatal dexamethasone treatment on proliferation and astrocyte immunoreactivity in hippocampus and corpus callosum: towards a rescue strategy.
    Brain research, 2012, Oct-30, Volume: 1482

    Topics: Age Factors; Animals; Animals, Newborn; Astrocytes; Body Weight; Cell Count; Cell Proliferation; Corpus Callosum; Dexamethasone; Drug Administration Routes; Glial Fibrillary Acidic Protein; Glucocorticoids; Hippocampus; Hormone Antagonists; Ki-67 Antigen; Mifepristone; Rats; Rats, Long-Evans

2012
A single-day treatment with mifepristone is sufficient to normalize chronic glucocorticoid induced suppression of hippocampal cell proliferation.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Animals; Body Weight; Cell Proliferation; Corticosterone; Dentate Gyrus; Doublecortin Protein; Glucocorticoids; Hippocampus; Immunohistochemistry; Male; Mifepristone; Rats; Rats, Wistar

2012
Effects of glucocorticoid receptor antagonist, RU486, on the proliferative and differentiation capabilities of bone marrow mesenchymal stromal cells in ovariectomized rats.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2013, Volume: 31, Issue:5

    Topics: Animals; Body Weight; Cell Differentiation; Cell Proliferation; Corticosterone; Estrogens; Female; Hormone Antagonists; Mesenchymal Stem Cells; Mifepristone; Models, Animal; Ovariectomy; Oxidative Stress; Phenols; Plant Extracts; Rats; Rats, Inbred F344; Receptors, Glucocorticoid; Superoxide Dismutase

2013
Restoration of neuroendocrine stress response by glucocorticoid receptor or GABA(A) receptor antagonists after experimental traumatic brain injury.
    Journal of neurotrauma, 2013, Jul-15, Volume: 30, Issue:14

    Topics: Amygdala; Analysis of Variance; Animals; Bicuculline; Body Weight; Brain Injuries; Cell Count; Corticosterone; Functional Laterality; GABA-A Receptor Antagonists; Glutamate Decarboxylase; Hippocampus; Hypothalamo-Hypophyseal System; Image Processing, Computer-Assisted; Immunohistochemistry; Male; Mifepristone; Neurosecretory Systems; Parvalbumins; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Stress, Physiological

2013
The role of glucocorticoid receptors in dexamethasone-induced apoptosis of neuroprogenitor cells in the hippocampus of rat pups.
    Mediators of inflammation, 2013, Volume: 2013

    Topics: Animals; Apoptosis; Blotting, Western; Body Weight; Brain; Dexamethasone; Female; Hippocampus; Immunohistochemistry; In Situ Nick-End Labeling; Mifepristone; Neural Stem Cells; Organ Size; Pregnancy; Rats; Rats, Wistar; Receptors, Glucocorticoid

2013
Glucocorticoid-induced skeletal muscle atrophy is associated with upregulation of myostatin gene expression.
    American journal of physiology. Endocrinology and metabolism, 2003, Volume: 285, Issue:2

    Topics: Animals; Body Weight; Dexamethasone; Gene Expression Regulation; Glucocorticoids; Kinetics; Male; Mifepristone; Muscle, Skeletal; Muscular Atrophy; Myostatin; Organ Size; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; RNA, Messenger; Transforming Growth Factor beta

2003
Progesterone increases blood pressure in spontaneous gestational hypertension in rats.
    American journal of hypertension, 2005, Volume: 18, Issue:1

    Topics: Animals; Aspartate Aminotransferases; Blood Pressure; Body Weight; Creatinine; Disease Models, Animal; Estrogens; Female; Hypertension, Pregnancy-Induced; Kidney; Male; Mifepristone; Pregnancy; Progesterone; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Systole

2005
Antiglucocorticoid RU38486 reduces net protein catabolism in experimental acute renal failure.
    BMC nephrology, 2005, Feb-17, Volume: 6

    Topics: Acidosis; Acute Kidney Injury; Amino Acids; Animals; Body Weight; Chromatography, High Pressure Liquid; Glucocorticoids; Hormone Antagonists; Male; Methylhistidines; Mifepristone; Muscle Proteins; Nephrectomy; Oxygen Consumption; Rats; Rats, Wistar; Uremia

2005
High levels of filamentous actin and apoptosis correlate with mast cell refractoriness under alloxan-evoked diabetes.
    Life sciences, 2006, Aug-15, Volume: 79, Issue:12

    Topics: Abortifacient Agents; Actins; Adrenalectomy; Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Blood Glucose; Blotting, Western; Body Weight; Cell Separation; Depsipeptides; Diabetes Mellitus, Experimental; Flow Cytometry; Glucocorticoids; Histamine Release; Male; Mast Cells; Microscopy, Fluorescence; Mifepristone; Prostaglandin D2; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar

2006
The efficacy of mifepristone in the reduction and prevention of olanzapine-induced weight gain in rats.
    Behavioural brain research, 2006, Aug-10, Volume: 171, Issue:2

    Topics: Abdominal Fat; Analysis of Variance; Animals; Antipsychotic Agents; Benzodiazepines; Body Weight; Dose-Response Relationship, Drug; Drug Interactions; Female; Hormone Antagonists; Mifepristone; Olanzapine; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Progesterone; Weight Gain

2006
Omega-3 fatty acid ethyl-eicosapentaenoate attenuates IL-1beta-induced changes in dopamine and metabolites in the shell of the nucleus accumbens: involved with PLA2 activity and corticosterone secretion.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Body Weight; Corticosterone; Dinoprostone; Dopamine; Drug Interactions; Eicosapentaenoic Acid; Homovanillic Acid; Hormone Antagonists; Interleukin-1beta; Male; Mifepristone; Nucleus Accumbens; Phospholipases A; Phospholipases A2; Rats; Rats, Sprague-Dawley

2007
Effect of chronic stress and mifepristone treatment on voltage-dependent Ca2+ currents in rat hippocampal dentate gyrus.
    Journal of neuroendocrinology, 2006, Volume: 18, Issue:10

    Topics: Animals; Body Weight; Calcium Channels, L-Type; Chronic Disease; Cold Temperature; Corticosterone; Crowding; Dentate Gyrus; Hormone Antagonists; Immobilization; In Vitro Techniques; Male; Membrane Potentials; Mifepristone; Milk; Organ Size; Patch-Clamp Techniques; Rats; Rats, Wistar; RNA, Messenger; Social Isolation; Stress, Psychological; Swimming

2006
Effects of mineralocorticoid and glucocorticoid receptor blockade on hypothalamic-pituitary-adrenal function in female rats prenatally exposed to ethanol.
    Alcoholism, clinical and experimental research, 2006, Volume: 30, Issue:11

    Topics: Adrenocorticotropic Hormone; Animals; Body Weight; Central Nervous System Depressants; Ethanol; Feedback; Female; Hormone Antagonists; Hydrocortisone; Hypothalamo-Hypophyseal System; Lactation; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Pituitary-Adrenal System; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Restraint, Physical; Spironolactone; Stress, Psychological

2006
Brief RU 38486 treatment normalizes the effects of chronic stress on calcium currents in rat hippocampal CA1 neurons.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:8

    Topics: Animals; Body Weight; Calcium; Corticosterone; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Hippocampus; Hormone Antagonists; In Vitro Techniques; Male; Membrane Potentials; Mifepristone; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Stress, Physiological

2007
Treatment of obesity and diabetes in mice by transplant of gut cells engineered to produce leptin.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2008, Volume: 16, Issue:6

    Topics: Adipose Tissue; Animals; Body Weight; Cell Transplantation; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Insulin; Kidney; Leptin; Mice; Mice, Obese; Mifepristone; Obesity; RNA, Messenger; Transfection

2008
Comparison of effects of adrenalectomy and RU-486 in rats given a choice of maintenance diet and fat supplement.
    The American journal of physiology, 1995, Volume: 269, Issue:3 Pt 2

    Topics: Adrenalectomy; Animals; Body Composition; Body Weight; Corticosterone; Diet; Dietary Fats; Eating; Energy Intake; Food Preferences; Glucose Intolerance; Insulin; Male; Mifepristone; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Triglycerides

1995
Involvement of corticosterone in the fasting-induced rise in protein utilization and locomotor activity.
    Pharmacology, biochemistry, and behavior, 1995, Volume: 50, Issue:3

    Topics: Adipose Tissue; Adrenal Glands; Animals; Body Weight; Circadian Rhythm; Corticosterone; Epididymis; Fasting; Male; Mifepristone; Motor Activity; Nitrogen; Proteins; Rats; Rats, Sprague-Dawley; Running

1995
Anordiol and RU486 synergize to produce preimplantation pregnancy loss by increasing embryo transport (rat).
    Contraception, 1995, Volume: 51, Issue:2

    Topics: Abortion, Induced; Animals; Body Weight; Drug Synergism; Embryonic Development; Female; Fetus; Mifepristone; Norandrostanes; Ovum Transport; Pregnancy; Rats; Rats, Wistar

1995
Consequence of long-term exposure to corticosterone or dexamethasone on ethanol consumption in the adrenalectomized rat, and the effect of type I and type II corticosteroid receptor antagonists.
    Psychopharmacology, 1995, Volume: 117, Issue:2

    Topics: Adrenalectomy; Alcohol Drinking; Animals; Body Weight; Corticosterone; Dexamethasone; Drinking; Drug Implants; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Organ Size; Rats; Rats, Wistar; Receptors, Steroid; Sodium Chloride; Spironolactone

1995
Thyroidal regulation of lingual lipase development in suckling rats.
    Biology of the neonate, 1993, Volume: 64, Issue:2-3

    Topics: Animals; Animals, Suckling; Body Weight; Dose-Response Relationship, Drug; Hypothyroidism; Lipase; Mifepristone; Pancreas; Propylthiouracil; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Thyroid Gland; Thyroxine; Tongue

1993
Development of specific antibody and in vivo response to antigen in different rat strains: effect of dexamethasone and importance of endogenous corticosteroids.
    Agents and actions, 1993, Volume: 39, Issue:3-4

    Topics: Adrenal Cortex Hormones; Animals; Antibody Specificity; Body Weight; Dexamethasone; Edema; Female; Freund's Adjuvant; Immunoglobulin E; Immunoglobulin G; Male; Mifepristone; Ovalbumin; Rats; Rats, Inbred BN; Rats, Inbred F344; Rats, Inbred Strains; Rats, Wistar; Species Specificity

1993
Effects of a specific glucocorticoid receptor antagonist on corticotropin releasing hormone gene expression in the paraventricular nucleus of the neonatal rat.
    Brain research. Developmental brain research, 1993, Jun-08, Volume: 73, Issue:2

    Topics: Animals; Animals, Newborn; Body Weight; Cholesterol; Corticotropin-Releasing Hormone; Cortisone; DNA Probes; Drug Implants; Female; Gene Expression; In Situ Hybridization; Male; Mifepristone; Paraventricular Hypothalamic Nucleus; Pregnancy; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; RNA, Messenger; Stress, Physiological; Up-Regulation

1993
The divergent effect of RU 486 on adrenal function in the dog is related to differences in its pharmacokinetics.
    Acta endocrinologica, 1993, Volume: 128, Issue:5

    Topics: Administration, Oral; Adrenal Cortex; Adrenocorticotropic Hormone; Analysis of Variance; Animals; Blood Proteins; Body Weight; Dogs; Female; Hydrocortisone; Hypoglycemia; Hypothalamo-Hypophyseal System; Insulin; Metyrapone; Mifepristone; Pituitary-Adrenal System; Time Factors

1993
Effects of the glucocorticoid agonist, RU28362, and the antagonist RU486 on lung phosphatidylcholine and antioxidant enzyme development in the genetically obese Zucker rat.
    Biochemical pharmacology, 1993, Feb-09, Volume: 45, Issue:3

    Topics: Androstanols; Animals; Body Weight; Eating; Glucocorticoids; Lung; Male; Mifepristone; Organ Size; Phospholipids; Rats; Rats, Zucker; Receptors, Glucocorticoid

1993
The effects of the antihormones RU486 and tamoxifen on fetoplacental development and placental bed vascularisation in the rat: a model for intrauterine fetal growth retardation.
    British journal of obstetrics and gynaecology, 1996, Volume: 103, Issue:7

    Topics: Abortifacient Agents, Steroidal; Animals; Body Weight; Embryo Implantation; Embryonic and Fetal Development; Estrogen Antagonists; Female; Immunohistochemistry; Mifepristone; Placenta; Placentation; Pregnancy; Rats; Rats, Wistar; Tamoxifen

1996
Involvement of type I corticosteroid receptor in the effects of ovariectomy on energy balance.
    The American journal of physiology, 1996, Volume: 270, Issue:1 Pt 2

    Topics: Animals; Body Weight; Energy Metabolism; Female; Lipid Metabolism; Mifepristone; Mineralocorticoid Receptor Antagonists; Ovariectomy; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone

1996
Predominately glucocorticoid agonist actions of RU-486 in young specific-pathogen-free Zucker rats.
    The American journal of physiology, 1996, Volume: 271, Issue:3 Pt 2

    Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Animals, Newborn; Blood Glucose; Body Weight; Eating; Female; Germ-Free Life; Glucocorticoids; Hormone Antagonists; Hormones; Male; Mifepristone; Obesity; Organ Size; Rats; Rats, Zucker; Reference Values

1996
In vivo antiestrogenic activity of mifepristone in the rat.
    Journal of endocrinological investigation, 1997, Volume: 20, Issue:4

    Topics: Animals; Body Weight; Corticosterone; Drug Combinations; Estradiol; Estrogen Antagonists; Injections, Subcutaneous; Male; Mifepristone; Organ Size; Pituitary Gland, Anterior; Rats; Rats, Wistar; Tamoxifen

1997
Increased hypothalamic neuropeptide Y concentration or hyperphagia in streptozotocin-diabetic rats are not mediated by glucocorticoids.
    European journal of pharmacology, 1997, Dec-11, Volume: 340, Issue:2-3

    Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Drinking; Eating; Hormone Antagonists; Hyperphagia; Hypothalamus; Insulin; Male; Mifepristone; Neuropeptide Y; Rats; Rats, Wistar; Receptors, Glucocorticoid

1997
Glucocorticoid blockade does not abrogate tumor-induced cachexia.
    Nutrition and cancer, 1999, Volume: 35, Issue:2

    Topics: Adenocarcinoma; Animals; Body Composition; Body Weight; Cachexia; Colonic Neoplasms; Female; Glucocorticoids; Hormone Antagonists; Interleukin-6; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Mifepristone; Neoplasm Transplantation; Regression Analysis; Tumor Cells, Cultured

1999
Enhanced intestinal synthesis of polyamines from proline in cortisol-treated piglets.
    American journal of physiology. Endocrinology and metabolism, 2000, Volume: 279, Issue:2

    Topics: Animals; Animals, Suckling; Arginine; Biogenic Polyamines; Body Weight; Eating; Enterocytes; Glutamine; Hydrocortisone; Jejunum; Mifepristone; Organ Size; Ornithine; Ornithine Decarboxylase; Proline; Swine

2000
Progestins block cholesterol synthesis to produce meiosis-activating sterols.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2001, Volume: 15, Issue:3

    Topics: Animals; Body Weight; Cholestadienols; Cholesterol; Estrogen Antagonists; Humans; Hydroxyprogesterones; Male; Meiosis; Miconazole; Mifepristone; Progestins; Rats; Spectrum Analysis; Sterols; Tamoxifen; Testis; Tumor Cells, Cultured

2001
Glucocorticoids and parental hyperphagia in ring doves (Streptopelia risoria).
    Hormones and behavior, 2002, Volume: 41, Issue:1

    Topics: Animals; Body Weight; Columbidae; Corticosterone; Dexamethasone; Dose-Response Relationship, Drug; Eating; Female; Glucocorticoids; Hormone Antagonists; Hyperphagia; Injections, Intramuscular; Injections, Intraventricular; Male; Mifepristone; Nesting Behavior

2002
The epidermis as a bioreactor: topically regulated cutaneous delivery into the circulation.
    Human gene therapy, 2002, Jun-10, Volume: 13, Issue:9

    Topics: Animals; Bioreactors; Body Weight; Epidermis; Feasibility Studies; Gene Expression Regulation; Gene Transfer Techniques; Human Growth Hormone; Humans; Keratinocytes; Mice; Mice, Nude; Mice, Transgenic; Mifepristone; Promoter Regions, Genetic; Receptors, Progesterone

2002
Role of the antiglucocorticoid RU 486 in the prevention of steroid-induced hypertension.
    Acta endocrinologica, 1992, Volume: 127, Issue:3

    Topics: Animals; Blood Pressure; Body Weight; Desoxycorticosterone; Hypertension; Male; Mifepristone; Rats; Rats, Sprague-Dawley; Reference Values; Sodium Chloride

1992
The progesterone antagonist, RU486 does not affect basal or estrogen-stimulated cancellous bone formation in the rat.
    Bone and mineral, 1992, Volume: 19, Issue:3

    Topics: Animals; Body Weight; Bone Development; Estradiol; Female; Mifepristone; Progesterone; Rats; Rats, Wistar; Tibia

1992
Effects of neonatal exposure to the antiprogestin mifepristone, RU 486, on the sexual development of the rat.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 41, Issue:1

    Topics: Animals; Animals, Newborn; Body Weight; Female; Genitalia, Female; Genitalia, Male; Male; Mifepristone; Ovariectomy; Rats; Receptors, Progesterone; Sex Characteristics; Sexual Behavior, Animal; Sexual Maturation

1992
Interactions between oestradiol and the progesterone antagonist RU-486 in establishing and maintaining female rats' sexual responsiveness: central versus peripheral effects.
    Behavioural brain research, 1992, Apr-10, Volume: 47, Issue:2

    Topics: Animals; Body Weight; Central Nervous System; Estradiol; Female; Mifepristone; Nociceptors; Organ Size; Ovariectomy; Progesterone; Rats; Rats, Inbred Strains; Sexual Behavior, Animal; Uterus

1992
Protective effects of ciprofloxacin against type II collagen induced arthritis in rats.
    The Journal of rheumatology, 1992, Volume: 19, Issue:2

    Topics: Adrenal Cortex Hormones; Adrenalectomy; Animals; Arthritis; Body Weight; Ciprofloxacin; Collagen; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glucocorticoids; Interleukin-1; Male; Mifepristone; Monocytes; Rats; Time Factors; Tumor Necrosis Factor-alpha

1992
Reduction of the intake of food and water is responsible for reduction of litter growth when dams are treated with a progesterone antagonist.
    The British journal of nutrition, 1991, Volume: 66, Issue:1

    Topics: Animals; Animals, Newborn; Body Weight; Drinking; Eating; Female; Gonanes; Lactation; Male; Mifepristone; Milk; Ovariectomy; Pregnancy; Progesterone; Rats; Rats, Inbred Strains

1991
Ineffectiveness of parenteral fluoxetine or RU-486 to alter long-term food intake, body weight or body composition of genetically obese mice.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:3

    Topics: Animals; Body Composition; Body Weight; Drug Administration Schedule; Eating; Female; Fluoxetine; Injections, Subcutaneous; Male; Mice; Mice, Obese; Mifepristone; Obesity; Parenteral Nutrition; Time Factors

1990
Effect of the progesterone antagonist mifepristone on the hypothalamo-hypophysial-ovarian axis in rats.
    The Journal of endocrinology, 1990, Volume: 124, Issue:3

    Topics: 20-alpha-Dihydroprogesterone; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Body Weight; Bromocriptine; Delayed-Action Preparations; Female; Gonanes; Hypothalamo-Hypophyseal System; Mifepristone; Organ Size; Ovary; Pituitary Gland; Progesterone; Prolactin; Rats; Uterus

1990
Effects of antiglucocorticoid RU 486 on development of obesity in obese fa/fa Zucker rats.
    The American journal of physiology, 1990, Volume: 259, Issue:3 Pt 2

    Topics: Animals; Body Composition; Body Weight; Brain; Corticosterone; Eating; Female; Glucocorticoids; Insulin; Mifepristone; Obesity; Organ Size; Rats; Rats, Zucker

1990
Role of antiglucocorticoid RU 486 on dexamethasone-induced hypertension in rats.
    The American journal of physiology, 1989, Volume: 256, Issue:5 Pt 1

    Topics: Animals; Blood Pressure; Body Weight; Dexamethasone; Estrenes; Glucocorticoids; Male; Mifepristone; Rats; Rats, Inbred Strains; Sodium; Thymus Gland

1989
Effects of the antiglucocorticoid RU 486 on adrenal function in dogs.
    The Journal of clinical endocrinology and metabolism, 1988, Volume: 66, Issue:3

    Topics: Administration, Oral; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Blood Proteins; Body Weight; Dogs; Estrenes; Female; Hematocrit; Hydrocortisone; Mifepristone

1988
Comparison of the actions of RU 38486 and megestrol acetate in the model of a transplantable adrenocorticotropin- and prolactin-secreting rat pituitary tumor.
    Cancer research, 1985, Volume: 45, Issue:3

    Topics: Adenocarcinoma; Adrenocorticotropic Hormone; Animals; Body Weight; Cells, Cultured; Estrenes; Female; Megestrol; Megestrol Acetate; Mifepristone; Neoplasm Transplantation; Organ Size; Pituitary Neoplasms; Prolactin; Rats; Rats, Inbred Strains; Receptors, Glucocorticoid

1985
Comparison of the actions of the antiprogestin mifepristone (RU486), the progestin megestrol acetate, the LHRH analog buserelin, and ovariectomy in treatment of rat mammary tumors.
    Cancer treatment reports, 1987, Volume: 71, Issue:11

    Topics: Animals; Body Weight; Buserelin; Combined Modality Therapy; Estrenes; Female; Follicle Stimulating Hormone; Luteinizing Hormone; Mammary Neoplasms, Experimental; Megestrol; Megestrol Acetate; Mifepristone; Ovariectomy; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone

1987
A possible role for endogenous glucocorticoids in orchiectomy-induced atrophy of the rat levator ani muscle: studies with RU 38486, a potent and selective antiglucocorticoid.
    Journal of steroid biochemistry, 1986, Volume: 25, Issue:3

    Topics: Animals; Atrophy; Body Weight; Dexamethasone; Estrenes; Glucocorticoids; Male; Mifepristone; Muscles; Orchiectomy; Rats; Receptors, Glucocorticoid; Time Factors; Triamcinolone Acetonide

1986