mifepristone has been researched along with Alloxan Diabetes in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (24.14) | 18.2507 |
| 2000's | 12 (41.38) | 29.6817 |
| 2010's | 9 (31.03) | 24.3611 |
| 2020's | 1 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Apelqvist, T; Barkhem, T; Färnegårdh, M; Fung, S; Goos-Nilsson, A; Grynfarb, M; Hagberg, L; Höglund, M; Hutchins, C; Jacobson, PB; Jae, HS; Jakob, C; Kauppi, B; Koehler, K; Kym, PR; Lai, C; Link, JT; Nguyen, P; Ohman, L; Osterlund, M; Rhonnstad, P; Sandberg, J; Tu, N; von Geldern, TW; Wang, J; Wilcox, D | 1 |
| Dehpour, AR; Hasanvand, A; Mokhtari, S; Shams, MH; Sistani Karampour, N | 1 |
| Afonnikova, ED; Kuz Minova, OI; Pal Chikova, NA; Selyatitskaya, VG | 1 |
| Kuz'minova, OI; Pal'chikova, NA; Pasechnaya, KV; Selyatitskaya, VG | 1 |
| Breivik, T; Gjermo, P; Gundersen, Y; Opstad, PK | 1 |
| López-Rubalcava, C; Oikawa, J; Paez-Martinez, N | 1 |
| Gerbek, YE; Kuznetsova, NV; Pal'chikova, NA; Selyatitskaya, VG | 1 |
| Akiyama, N; Akiyama, Y; Asakura, K; Hanasaki, K; Imagawa, K; Kato, H; Kuroda, T; Murayama, T; Ono, T; Shinosaki, T | 1 |
| Beaudry, JL; Belanoff, JK; Dunford, EC; Hunt, H; Riddell, MC; Teich, T; Zaharieva, D | 1 |
| Kuzminova, OI; Kuznetsova, NV; Palchikova, NA; Selyatitskaya, VG | 1 |
| de Kloet, ER; De Nicola, AF; Louwe, MC; Oitzl, MS; Rekers, NV; Revsin, Y; Saravia, FE | 1 |
| Jefferson, LS; Kimball, SR; McGhee, NK | 1 |
| Barreto, Ede O; Carvalho, Vde F; Cordeiro, RS; Farias-Filho, FA; Gomes, LH; Martins, MA; Mendonça, Lde L; Rodrigues e Silva, PM | 1 |
| Cheung, AT; Donald, C; Gunn, V; Kieffer, TJ; Unniappan, S; Wall, JL; Webber, TD; Wideman, RD; Zhang, QX | 1 |
| Kou, ZZ; Li, YQ; Liu, XZ; Luo, DS; Niu, L; Wang, W; Wu, SX; Zhang, FX; Zhang, T; Zhao, XH; Zhu, C; Zuo, ZF | 1 |
| Auwerx, J; Lydon, J; O'Malley, BW; Picard, F; Schoonjans, K; Wanatabe, M | 1 |
| Azevedo, V; Barreto, EO; Carvalho, VF; Cordeiro, RS; Diaz, BL; e Silva, PM; Martins, MA; Serra, MF | 1 |
| Barja-Fidalgo, TC; Barreto, EO; Bertho, AL; Carvalho, VF; Cordeiro, RS; e Silva, PM; Martins, MA; Oliveira, MS | 1 |
| Bruch, D; Harb, G; Kieffer, TJ; Korbutt, GS; Lam, AW; Lam, NT; Oosman, SN; Unniappan, S; Webber, T; Zhang, QX | 1 |
| Inman, LR; Johnson, JH; Ohneda, M; Unger, RH | 1 |
| Brignone, JA; de Brignone, CM; de Mignone, IR; Ricci, CR; Rodríguez, RR; Susemihl, MC | 1 |
| Collins, S; Gettys, TW; Taylor, IL; Watson, PM | 1 |
| Burns, SJ; Dryden, S; Frankish, HM; Williams, G | 1 |
| Bitar, MS; Farook, T; Francis, IM; Wahid, S | 1 |
| Bajic, KT; Bitar, MS; Farook, T; Pilcher, CW; Thomas, MI | 1 |
| Bitar, MS; Farook, T; Francis, IM; John, B | 1 |
| Bitar, MS | 2 |
| Barreto, E; Cordeiro, R; Diaz, B; Martins, M; Perretti, M; Silva, P | 1 |
29 other study(ies) available for mifepristone and Alloxan Diabetes
| Article | Year |
|---|---|
Liver-selective glucocorticoid antagonists: a novel treatment for type 2 diabetes.
Topics: Animals; Bile Acids and Salts; Binding Sites; Bridged-Ring Compounds; Cells, Cultured; CHO Cells; Computer Simulation; Cricetinae; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose; Humans; Hypoglycemic Agents; Hypothalamo-Hypophyseal System; Liver; Male; Mice; Models, Molecular; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Structure-Activity Relationship | 2004 |
Protective assessment of progesterone and its receptor on experimental diabetic neuropathy: Antioxidant and anti-inflammatory effects.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Inflammation; Male; Mifepristone; Oxidative Stress; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, Progesterone; Sciatic Nerve | 2023 |
[Hypercorticism during streptozotocin diabetes and mifepristone administration: the role of cyclic adenosine monophosphate].
Topics: Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Animals; Corticosterone; Cyclic AMP; Diabetes Mellitus, Experimental; Mifepristone; Rats | 2019 |
Effects Mifepristone on Aminotransferase Activities in the Liver in Rats with Streptozotocin-Induced Diabetes Mellitus.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Glucose; Corticosterone; Diabetes Mellitus, Experimental; Glucocorticoids; Liver; Male; Mifepristone; Rats; Rats, Wistar; Tyrosine Transaminase | 2018 |
Chronic treatment with the glucocorticoid receptor antagonist RU486 inhibits diabetes-induced enhancement of experimental periodontitis.
Topics: Alveolar Bone Loss; Animals; Blood Glucose; Body Weight; Corticosterone; Diabetes Mellitus, Experimental; Drug Implants; Escherichia coli; Hormone Antagonists; Hypothalamo-Hypophyseal System; Interleukin-10; Lipopolysaccharides; Mifepristone; Periodontitis; Pituitary-Adrenal System; Placebos; Radiography; Random Allocation; Rats; Receptors, Glucocorticoid; Streptozocin; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2014 |
Blockade of corticosteroid receptors induces anxiolytic-like effects in streptozotocin-induced diabetic mice, and synergizes with diazepam.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Blood Glucose; Diabetes Mellitus, Experimental; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Hormone Antagonists; Mice; Mifepristone; Mineralocorticoid Receptor Antagonists; Motor Activity; Receptors, Steroid; Spironolactone; Time Factors | 2013 |
Effect of mifepristone on glucocorticoid receptor gene expression in the liver of rats with streptozotocin-induced diabetes.
Topics: Animals; Blood Glucose; Corticosterone; Diabetes Mellitus, Experimental; Gene Expression; Hormone Antagonists; Liver; Male; Mifepristone; Rats; Rats, Wistar; Receptors, Glucocorticoid; RNA, Messenger; Tyrosine Transaminase | 2013 |
Pharmacological evaluation of adipose dysfunction via 11β-hydroxysteroid dehydrogenase type 1 in the development of diabetes in diet-induced obese mice with cortisone pellet implantation.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipose Tissue; Animals; Cortisone; Diabetes Mellitus, Experimental; Diet, High-Fat; Glucocorticoids; Glucose; Insulin Resistance; Mice; Mice, Inbred C57BL; Mifepristone; Obesity; Receptors, Glucocorticoid; Up-Regulation | 2014 |
Effects of selective and non-selective glucocorticoid receptor II antagonists on rapid-onset diabetes in young rats.
Topics: Animals; Blood Glucose; Body Weight; Corticosterone; Diabetes Mellitus, Experimental; Diet, High-Fat; Hormone Antagonists; Insulin; Insulin Resistance; Male; Mifepristone; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Small Molecule Libraries | 2014 |
Effect of Mifepristone on Corticosteroid Production in Vitro by Adrenal Glands of Rats with Streptozotocin Diabetes.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Corticosterone; Diabetes Mellitus, Experimental; Hormone Antagonists; Hyperglycemia; Injections, Intraperitoneal; Male; Mifepristone; Organ Culture Techniques; Pregnenolone; Rats; Rats, Wistar; Sodium Chloride; Streptozocin | 2017 |
Glucocorticoid receptor blockade normalizes hippocampal alterations and cognitive impairment in streptozotocin-induced type 1 diabetes mice.
Topics: Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Animals; Cell Proliferation; Cognition; Corticosterone; Diabetes Mellitus, Experimental; Exploratory Behavior; Glial Fibrillary Acidic Protein; Gliosis; Hippocampus; Ki-67 Antigen; Male; Memory; Mice; Mice, Inbred C57BL; Mifepristone; Nerve Tissue Proteins; Proto-Oncogene Proteins c-jun; Receptors, Glucocorticoid | 2009 |
Elevated corticosterone associated with food deprivation upregulates expression in rat skeletal muscle of the mTORC1 repressor, REDD1.
Topics: Animals; Corticosterone; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; DNA Damage; DNA-Binding Proteins; Food Deprivation; Insulin; Male; Mifepristone; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Repressor Proteins; RNA, Messenger; Signal Transduction; Transcription Factors; Up-Regulation | 2009 |
Reduced expression of IL-3 mediates intestinal mast cell depletion in diabetic rats: role of insulin and glucocorticoid hormones.
Topics: Animals; Cell Count; Diabetes Mellitus, Experimental; Down-Regulation; Glucocorticoids; Hormone Antagonists; Ileum; Insulin; Interleukin-3; Male; Mast Cells; Mifepristone; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2009 |
Treatment of diabetes by transplantation of drug-inducible insulin-producing gut cells.
Topics: Animals; Cell Line, Tumor; Cell- and Tissue-Based Therapy; Diabetes Mellitus, Experimental; Gene Expression Regulation; Hormone Antagonists; Humans; Insulin; Intestinal Mucosa; Intestines; Male; Mice; Mice, Inbred BALB C; Mifepristone; Time Factors | 2009 |
RU486 (mifepristone) ameliorates cognitive dysfunction and reverses the down-regulation of astrocytic N-myc downstream-regulated gene 2 in streptozotocin-induced type-1 diabetic rats.
Topics: Animals; Astrocytes; Cognition; Cognition Disorders; Corticosterone; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Down-Regulation; Male; Maze Learning; Mifepristone; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Streptozocin | 2011 |
Progesterone receptor knockout mice have an improved glucose homeostasis secondary to beta -cell proliferation.
Topics: Animals; Blood Glucose; Cell Count; Cell Division; Cell Size; Diabetes Mellitus, Experimental; Diabetes, Gestational; Female; Glucose; Glucose Tolerance Test; Homeostasis; Hormone Antagonists; Hyperglycemia; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mifepristone; Organ Size; Pregnancy; Progesterone; Receptors, Progesterone; Sex Characteristics; Signal Transduction | 2002 |
Systemic anaphylaxis is prevented in alloxan-diabetic rats by a mechanism dependent on glucocorticoids.
Topics: Anaphylaxis; Animals; Diabetes Mellitus, Experimental; Glucocorticoids; Male; Mifepristone; Rats; Rats, Wistar; Receptors, Glucocorticoid | 2003 |
High levels of filamentous actin and apoptosis correlate with mast cell refractoriness under alloxan-evoked diabetes.
Topics: Abortifacient Agents; Actins; Adrenalectomy; Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Blood Glucose; Blotting, Western; Body Weight; Cell Separation; Depsipeptides; Diabetes Mellitus, Experimental; Flow Cytometry; Glucocorticoids; Histamine Release; Male; Mast Cells; Microscopy, Fluorescence; Mifepristone; Prostaglandin D2; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar | 2006 |
Treatment of obesity and diabetes in mice by transplant of gut cells engineered to produce leptin.
Topics: Adipose Tissue; Animals; Body Weight; Cell Transplantation; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Insulin; Kidney; Leptin; Mice; Mice, Obese; Mifepristone; Obesity; RNA, Messenger; Transfection | 2008 |
GLUT-2 function in glucose-unresponsive beta cells of dexamethasone-induced diabetes in rats.
Topics: 3-O-Methylglucose; Animals; Arginine; Biological Transport; Blood Glucose; Dexamethasone; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Transporter Type 2; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Methylglucosides; Mifepristone; Monosaccharide Transport Proteins; Rats; Rats, Zucker | 1993 |
Favourable, significant effect of the dose-dependent treatment with RU 38486 (RU) on the alterations of the hepatic mitochondrial function of diabetic rats.
Topics: 3-Hydroxybutyric Acid; Adrenalectomy; Animals; Anti-Inflammatory Agents; Corticosterone; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Electron Transport Complex IV; Female; Hormone Antagonists; Hydroxybutyrate Dehydrogenase; Hydroxybutyrates; Malates; Mifepristone; Mitochondria, Liver; Oxygen Consumption; Rats; Succinates; Succinic Acid | 1996 |
RU-486 (Mifepristone) ameliorates diabetes but does not correct deficient beta-adrenergic signalling in adipocytes from mature C57BL/6J-ob/ob mice.
Topics: Adenylyl Cyclases; Adipose Tissue; Adrenergic beta-Agonists; Animals; Blood Glucose; Blotting, Northern; Blotting, Western; Colforsin; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Activation; Ethanolamines; Glucose Transporter Type 4; GTP-Binding Protein alpha Subunits, Gs; Hormone Antagonists; Insulin; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Mifepristone; Monosaccharide Transport Proteins; Muscle Proteins; Phenotype; Receptors, Adrenergic, beta; Receptors, Glucocorticoid; Signal Transduction | 1997 |
Increased hypothalamic neuropeptide Y concentration or hyperphagia in streptozotocin-diabetic rats are not mediated by glucocorticoids.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Drinking; Eating; Hormone Antagonists; Hyperphagia; Hypothalamus; Insulin; Male; Mifepristone; Neuropeptide Y; Rats; Rats, Wistar; Receptors, Glucocorticoid | 1997 |
Glucocorticoid-dependent impairment of wound healing in experimental diabetes: amelioration by adrenalectomy and RU 486.
Topics: Adrenalectomy; Animals; Diabetes Mellitus, Experimental; Glucocorticoids; Hormone Antagonists; Hypoglycemic Agents; Insulin; Male; Mifepristone; Rats; Rats, Sprague-Dawley; Skin; Wound Healing; Wounds, Penetrating | 1999 |
Spinal cord noradrenergic dynamics in diabetic and hypercortisolaemic states.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Female; Hormone Antagonists; Hydrocortisone; Male; Methoxyhydroxyphenylglycol; Mifepristone; Norepinephrine; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Spinal Cord | 1999 |
Heat-shock protein 72/73 and impaired wound healing in diabetic and hypercortisolemic states.
Topics: Animals; Blood Glucose; Blotting, Western; Diabetes Mellitus, Experimental; HSP70 Heat-Shock Proteins; Hydrocortisone; Immunohistochemistry; Male; Mifepristone; Rats; Rats, Sprague-Dawley; Wound Healing | 1999 |
Insulin and glucocorticoid-dependent suppression of the IGF-I system in diabetic wounds.
Topics: Animals; Base Sequence; Diabetes Mellitus, Experimental; DNA Primers; Gene Expression; Glucocorticoids; Hormone Antagonists; Insulin; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Male; Mifepristone; Rats; Rats, Wistar; Receptor, IGF Type 1; Wound Healing; Wounds and Injuries | 2000 |
Enhanced serum glucocorticoid levels mediate the reduction of serosal mast cell numbers in diabetic rats.
Topics: Adrenalectomy; Animals; Blood Glucose; Corticosterone; Diabetes Mellitus, Experimental; Glucocorticoids; Hyperglycemia; Insulin; Male; Mast Cells; Mifepristone; Pleura; Rats; Rats, Wistar | 2001 |
Co-administration of etomoxir and RU-486 mitigates insulin resistance in hepatic and muscular tissues of STZ-induced diabetic rats.
Topics: Animals; Carnitine O-Palmitoyltransferase; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Enzyme Inhibitors; Epoxy Compounds; Fatty Acids, Nonesterified; Glucose; Hormone Antagonists; Insulin Resistance; Liver; Male; Mifepristone; Mitochondria; Muscle, Skeletal; Rats; Rats, Wistar | 2001 |