Page last updated: 2024-08-23

mifepristone and Alcohol Drinking

mifepristone has been researched along with Alcohol Drinking in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (18.75)18.2507
2000's4 (25.00)29.6817
2010's5 (31.25)24.3611
2020's4 (25.00)2.80

Authors

AuthorsStudies
Aoun, EG; Brown, JC; Cannella, N; Ciccocioppo, R; Cioe, PA; Haass-Koffler, CL; Leggio, L; Magill, M; Sinha, R; Swift, RM1
Gainey, SC; Logrip, ML1
Bauder, M; Crabbe, JC; Hack, WR; Hausch, F; Hunt, H; LeMoine, K; Metten, P; Ozburn, AR; Savarese, AM; Schlumbohm, JP1
Diem, K; Grant, KA; Hunt, H; Jimenez, VA; Newman, N; Shnitko, TA; Vanderhooft, L; Walter, NAR1
Belanoff, JK; Edwards, S; Estey, D; George, O; Goodell, V; Hunt, HJ; Koob, GF; Logrip, ML; Macshane, LG; Mason, BJ; McGinn, MA; Sanna, PP; Schlosburg, JE; Vendruscolo, LF; Zamora-Martinez, ER1
Coulton, S; Donoghue, K; Drummond, C; Little, H; Milward, J; Reed, K; Rose, A1
Croft, AP; Jacquot, C; Little, HJ; Mulholland, P; Prendergast, MA; Shaw, SG1
Amato, D; Biermann, T; Desrivieres, S; Kornhuber, J; Müller, CP; Rotter, A; Schumann, G1
Barbier, E; Heilig, M; Koob, GF; Logrip, ML; Misra, KK; Repunte-Canonigo, V; Rivier, C; Sanna, PP; Schlosburg, JE; Vendruscolo, LF; Whitfield, TW; Zorrilla, EP1
Costin, BN; Fitting, S; Miles, MF; Shelton, KL; Wolen, AR1
Koenig, HN; Olive, MF1
Croft, AP; Jacquot, C; Little, HJ; O'Callaghan, MJ1
Munro, CA; Rice, KC; Wand, GS; Wang, S; Yang, X1
Engel, JA; Eriksson, CJ; Fahlke, C; Hansen, S; Hård, E1
Fahlke, C; Hansen, S; Hård, E1
Carroll, JL; Pruett, SB; Vinson, RB1

Trials

3 trial(s) available for mifepristone and Alcohol Drinking

ArticleYear
Mifepristone as a pharmacological intervention for stress-induced alcohol craving: A human laboratory study.
    Addiction biology, 2023, Volume: 28, Issue:7

    Topics: Alcohol Drinking; Alcoholism; Craving; Double-Blind Method; Ethanol; Humans; Hydrocortisone; Mifepristone

2023
Glucocorticoid receptor antagonism decreases alcohol seeking in alcohol-dependent individuals.
    The Journal of clinical investigation, 2015, Aug-03, Volume: 125, Issue:8

    Topics: Administration, Oral; Adult; Alcohol Drinking; Alcoholism; Animals; Female; Hormone Antagonists; Humans; Male; Mifepristone; Rats; Receptors, Glucocorticoid

2015
Double-blind, 12 month follow-up, placebo-controlled trial of mifepristone on cognition in alcoholics: the MIFCOG trial protocol.
    BMC psychiatry, 2016, Feb-24, Volume: 16

    Topics: Adult; Alcohol Drinking; Alcoholics; Alcoholism; Cognition Disorders; Double-Blind Method; Follow-Up Studies; Humans; Male; Middle Aged; Mifepristone; Substance Withdrawal Syndrome

2016

Other Studies

13 other study(ies) available for mifepristone and Alcohol Drinking

ArticleYear
Sex differences in the long-term effects of past stress on alcohol self-administration, glucocorticoid sensitivity and phosphodiesterase 10A expression.
    Neuropharmacology, 2020, 03-01, Volume: 164

    Topics: Alcohol Drinking; Animals; Brain Chemistry; Central Nervous System Depressants; Electroshock; Ethanol; Extinction, Psychological; Female; Glucocorticoids; Male; Mifepristone; Phosphoric Diester Hydrolases; Rats; Rats, Wistar; Self Administration; Sex Characteristics; Stress, Psychological

2020
Targeting the Glucocorticoid Receptor Reduces Binge-Like Drinking in High Drinking in the Dark (HDID-1) Mice.
    Alcoholism, clinical and experimental research, 2020, Volume: 44, Issue:5

    Topics: Alcohol Drinking; Animals; Aversive Agents; Binge Drinking; Ethanol; Female; Isoquinolines; Male; Mice; Mifepristone; Pyrazoles; Receptors, Glucocorticoid; Tacrolimus Binding Proteins

2020
Mifepristone Decreases Chronic Voluntary Ethanol Consumption in Rhesus Macaques.
    The Journal of pharmacology and experimental therapeutics, 2020, Volume: 375, Issue:2

    Topics: Alcohol Drinking; Animals; Drinking; Macaca mulatta; Male; Mifepristone; Self Administration

2020
Effects of the glucocorticoid antagonist, mifepristone, on the consequences of withdrawal from long term alcohol consumption.
    Alcoholism, clinical and experimental research, 2008, Volume: 32, Issue:12

    Topics: Alcohol Drinking; Animals; Glucocorticoids; Hormone Antagonists; Male; Memory Disorders; Mice; Mice, Inbred C57BL; Mifepristone; Substance Withdrawal Syndrome

2008
Glucocorticoid receptor antagonism blocks ethanol-induced place preference learning in mice and attenuates dopamine D2 receptor adaptation in the frontal cortex.
    Brain research bulletin, 2012, Aug-01, Volume: 88, Issue:5

    Topics: Adaptation, Physiological; Alcohol Drinking; Animals; Conditioning, Operant; Dopamine D2 Receptor Antagonists; Ethanol; Frontal Lobe; Learning; Male; Mice; Mice, Inbred DBA; Mifepristone; Receptors, Dopamine D2; Receptors, Glucocorticoid

2012
Corticosteroid-dependent plasticity mediates compulsive alcohol drinking in rats.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, May-30, Volume: 32, Issue:22

    Topics: Alcohol Drinking; Analysis of Variance; Animals; Behavior, Addictive; Brain; Central Nervous System Depressants; Compulsive Behavior; Conditioning, Operant; Ethanol; Hormone Antagonists; Male; Mifepristone; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Reinforcement Schedule; RNA, Messenger; Self Administration; Substance Withdrawal Syndrome; Up-Regulation

2012
Role of adrenal glucocorticoid signaling in prefrontal cortex gene expression and acute behavioral responses to ethanol.
    Alcoholism, clinical and experimental research, 2013, Volume: 37, Issue:1

    Topics: Adrenalectomy; Alcohol Drinking; Animals; Central Nervous System Depressants; Ethanol; Gene Expression Regulation; Glucocorticoids; Hormone Antagonists; Male; Mice; Mice, Inbred DBA; Mifepristone; Motor Activity; Oligonucleotide Array Sequence Analysis; Prefrontal Cortex; Reflex, Righting

2013
The glucocorticoid receptor antagonist mifepristone reduces ethanol intake in rats under limited access conditions.
    Psychoneuroendocrinology, 2004, Volume: 29, Issue:8

    Topics: Alcohol Drinking; Animals; Choice Behavior; Dose-Response Relationship, Drug; Drinking; Drinking Behavior; Ethanol; Hormone Antagonists; Male; Mifepristone; Rats; Rats, Long-Evans; Receptors, Glucocorticoid; Spironolactone

2004
The hypothalamopituitary-adrenal axis and alcohol preference.
    Brain research bulletin, 2005, Dec-30, Volume: 68, Issue:3

    Topics: Adrenocorticotropic Hormone; Alcohol Drinking; Animals; Animals, Newborn; Behavior, Animal; Central Nervous System Depressants; Conditioning, Operant; Corticosterone; Corticotropin-Releasing Hormone; Drug Administration Schedule; Enzyme Inhibitors; Ethanol; Hormone Antagonists; Hypothalamo-Hypophyseal System; Metyrapone; Mice; Mifepristone; Pituitary-Adrenal System; Time Factors

2005
Restraint stress and ethanol consumption in two mouse strains.
    Alcoholism, clinical and experimental research, 2008, Volume: 32, Issue:5

    Topics: Alcohol Drinking; Animals; Corticosterone; Glucocorticoids; Hypothalamo-Hypophyseal System; Male; Mice; Mice, Inbred C57BL; Mifepristone; Pituitary-Adrenal System; Pyrimidines; Receptors, Corticotropin-Releasing Hormone; Stress, Physiological

2008
Consequence of long-term exposure to corticosterone or dexamethasone on ethanol consumption in the adrenalectomized rat, and the effect of type I and type II corticosteroid receptor antagonists.
    Psychopharmacology, 1995, Volume: 117, Issue:2

    Topics: Adrenalectomy; Alcohol Drinking; Animals; Body Weight; Corticosterone; Dexamethasone; Drinking; Drug Implants; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Organ Size; Rats; Rats, Wistar; Receptors, Steroid; Sodium Chloride; Spironolactone

1995
Facilitation of ethanol consumption by intracerebroventricular infusions of corticosterone.
    Psychopharmacology, 1996, Volume: 127, Issue:2

    Topics: Adrenalectomy; Alcohol Drinking; Animals; Corticosterone; Drinking; Injections, Intraventricular; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Rats; Rats, Wistar; Receptors, Glucocorticoid; Spironolactone

1996
Mechanism of suppressed neutrophil mobilization in a mouse model for binge drinking: role of glucocorticoids.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: Alcohol Drinking; Animals; Corticosterone; Disease Models, Animal; Ethanol; Female; Inflammation; Macrophages, Peritoneal; Mice; Mice, Inbred Strains; Mifepristone; Neutrophil Activation; Neutrophils; Peritoneal Cavity; Propionibacterium acnes; Tumor Necrosis Factor-alpha

1998