Page last updated: 2024-08-23

mifepristone and Alcohol Abuse

mifepristone has been researched along with Alcohol Abuse in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (16.67)18.2507
2000's0 (0.00)29.6817
2010's7 (58.33)24.3611
2020's3 (25.00)2.80

Authors

AuthorsStudies
Bajo, M; Gandhi, P; Khom, S; Kirson, D; Mason, BJ; Oleata, CS; Roberto, M; Rodriguez, L; Vendruscolo, LF1
Aoun, EG; Brown, JC; Cannella, N; Ciccocioppo, R; Cioe, PA; Haass-Koffler, CL; Leggio, L; Magill, M; Sinha, R; Swift, RM1
Coleman, R; Coulton, S; Donoghue, K; Drummond, C; Little, H; Milward, J; Philips, T; Rose, A1
Berry, JN; Butler, TR; Prendergast, MA; Reynolds, AR; Sharrett-Field, L1
Howland, RH1
Alvarez, M; Califano, A; Kawamura, T; Koob, GF; Lefebvre, C; Repunte-Canonigo, V; Sanna, PP; Schlosburg, JE; Shin, W; van der Stap, L; Vendruscolo, LF1
Belanoff, JK; Edwards, S; Estey, D; George, O; Goodell, V; Hunt, HJ; Koob, GF; Logrip, ML; Macshane, LG; Mason, BJ; McGinn, MA; Sanna, PP; Schlosburg, JE; Vendruscolo, LF; Zamora-Martinez, ER1
Coulton, S; Donoghue, K; Drummond, C; Little, H; Milward, J; Reed, K; Rose, A1
Dani, JA; Doyon, WM; Karsch, JS; Kimmey, BA; Ostroumov, A; Thomas, AM1
Bartlett, SE; Bito-Onon, J; Haass-Koffler, CL; Li, R; Simms, JA1
Han, YC; Pruett, SB1
Pruett, SB; Wu, WJ1

Reviews

1 review(s) available for mifepristone and Alcohol Abuse

ArticleYear
Mifepristone as a therapeutic agent in psychiatry.
    Journal of psychosocial nursing and mental health services, 2013, Volume: 51, Issue:6

    Topics: Affective Disorders, Psychotic; Alcoholism; Antipsychotic Agents; Clinical Trials as Topic; Cocaine-Related Disorders; Hormone Antagonists; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Mental Disorders; Mifepristone; Pituitary-Adrenal System; Psychotic Disorders; Stress Disorders, Post-Traumatic; Weight Gain

2013

Trials

4 trial(s) available for mifepristone and Alcohol Abuse

ArticleYear
Mifepristone as a pharmacological intervention for stress-induced alcohol craving: A human laboratory study.
    Addiction biology, 2023, Volume: 28, Issue:7

    Topics: Alcohol Drinking; Alcoholism; Craving; Double-Blind Method; Ethanol; Humans; Hydrocortisone; Mifepristone

2023
Double-blind, placebo-controlled trial of mifepristone on cognition and depression in alcohol dependence.
    Trials, 2020, Sep-16, Volume: 21, Issue:1

    Topics: Alcoholism; Cognition; Depression; Double-Blind Method; Humans; Male; Mifepristone; Treatment Outcome

2020
Glucocorticoid receptor antagonism decreases alcohol seeking in alcohol-dependent individuals.
    The Journal of clinical investigation, 2015, Aug-03, Volume: 125, Issue:8

    Topics: Administration, Oral; Adult; Alcohol Drinking; Alcoholism; Animals; Female; Hormone Antagonists; Humans; Male; Mifepristone; Rats; Receptors, Glucocorticoid

2015
Double-blind, 12 month follow-up, placebo-controlled trial of mifepristone on cognition in alcoholics: the MIFCOG trial protocol.
    BMC psychiatry, 2016, Feb-24, Volume: 16

    Topics: Adult; Alcohol Drinking; Alcoholics; Alcoholism; Cognition Disorders; Double-Blind Method; Follow-Up Studies; Humans; Male; Middle Aged; Mifepristone; Substance Withdrawal Syndrome

2016

Other Studies

7 other study(ies) available for mifepristone and Alcohol Abuse

ArticleYear
Alcohol dependence and withdrawal increase sensitivity of central amygdalar GABAergic synapses to the glucocorticoid receptor antagonist mifepristone in male rats.
    Neurobiology of disease, 2022, Volume: 164

    Topics: Alcoholism; Amygdala; Animals; GABAergic Neurons; Hormone Antagonists; Inhibitory Postsynaptic Potentials; Male; Mifepristone; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Synapses

2022
Mifepristone pretreatment reduces ethanol withdrawal severity in vivo.
    Alcoholism, clinical and experimental research, 2013, Volume: 37, Issue:8

    Topics: Alcoholism; Animals; Body Weight; Corticosterone; Drug Evaluation, Preclinical; Eating; Ethanol; Hormone Antagonists; Male; Mifepristone; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Severity of Illness Index; Substance Withdrawal Syndrome

2013
Identifying candidate drivers of alcohol dependence-induced excessive drinking by assembly and interrogation of brain-specific regulatory networks.
    Genome biology, 2015, Feb-02, Volume: 16

    Topics: Alcoholism; Algorithms; Animals; Brain; Ethanol; Gene Regulatory Networks; Genes, Regulator; Hormone Antagonists; Mifepristone; Rats; Receptors, Glucocorticoid; Self Administration

2015
Stress Increases Ethanol Self-Administration via a Shift toward Excitatory GABA Signaling in the Ventral Tegmental Area.
    Neuron, 2016, Oct-19, Volume: 92, Issue:2

    Topics: Acetazolamide; Alcoholism; Animals; Carbonic Anhydrase Inhibitors; Central Nervous System Depressants; Conditioning, Operant; Dopamine; Dopaminergic Neurons; Ethanol; gamma-Aminobutyric Acid; Hormone Antagonists; K Cl- Cotransporters; Male; Microdialysis; Mifepristone; Patch-Clamp Techniques; Rats; Rats, Long-Evans; Receptors, GABA-A; Self Administration; Stress, Psychological; Symporters; Ventral Tegmental Area

2016
Mifepristone in the central nucleus of the amygdala reduces yohimbine stress-induced reinstatement of ethanol-seeking.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:4

    Topics: Alcohol-Induced Disorders, Nervous System; Alcoholism; Amygdala; Animals; Disease Models, Animal; Drug Interactions; Hormone Antagonists; Male; Mifepristone; Rats; Rats, Long-Evans; Secondary Prevention; Stress, Physiological; Yohimbine

2012
Mechanisms of ethanol-induced suppression of a primary antibody response in a mouse model for binge drinking.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 275, Issue:2

    Topics: Acetaldehyde; Acetates; Alcoholism; Animals; Antibody Formation; Antibody-Producing Cells; Base Sequence; Cells, Cultured; DNA Primers; Erythrocytes; Ethanol; Female; Gene Expression; Hormone Antagonists; Interleukin-1; Interleukin-2; Interleukin-4; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mifepristone; Molecular Sequence Data; RNA, Messenger

1995
Suppression of splenic natural killer cell activity in a mouse model for binge drinking. II. Role of the neuroendocrine system.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 278, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alcoholism; Animals; Azides; Benzodiazepines; Carbolines; Catecholamines; Corticosterone; Diazepam; Disease Models, Animal; Female; GABA-A Receptor Agonists; Glucocorticoids; Immunity, Cellular; Immunity, Innate; Killer Cells, Natural; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mifepristone; Nadolol; Naltrexone; Neurosecretory Systems; Oxidopamine; Phentolamine; Picrotoxin; Propranolol; Receptors, GABA-A; Spleen; Sympathetic Nervous System

1996