mifepristone has been researched along with Aging in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.23) | 18.7374 |
| 1990's | 9 (29.03) | 18.2507 |
| 2000's | 15 (48.39) | 29.6817 |
| 2010's | 6 (19.35) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Agorastos, A; Demiralay, C; Steiger, A; Wiedemann, K | 1 |
| Argenton, F; Benato, F; Colletti, E; Colombo, L; Dalla Valle, L; Moro, E; Skobo, T | 1 |
| Amat, J; Barrientos, RM; Crysdale, NY; Frank, MG; Hale, MW; Hennessey, PA; Kitt, MM; Lowry, CA; Maier, SF; Spencer, RL; Stamper, CE; Thompson, VM; Watkins, LR | 1 |
| Bacman, SR; Dillon, LM; Hida, A; Malek, TR; Moraes, CT; Morton, PD; Pickrell, AM; Pinto, M; Wang, X; Williams, SL; Yu, A | 1 |
| Choi, HI; Douard, V; Elshenawy, S; Ferraris, RP; Lagunoff, D | 1 |
| Poirier, L; Seroude, L; Shane, A; Zheng, J | 1 |
| Alberini, CM; New, AS; Riceberg, JS; Taubenfeld, SM | 1 |
| Berger, S; Deussing, JM; Ganea, K; Holsboer, F; Liebl, C; Müller, MB; Niederleitner, B; Schmidt, MV; Schütz, G; Sterlemann, V; Wagner, K | 1 |
| Curtis, C; Shen, J; Tavaré, S; Tower, J | 1 |
| Ling, D; Salvaterra, PM | 1 |
| Hardy, J; Kerr, F; Lovestone, S; Martinez, P; Partridge, L; Rogers, I | 1 |
| Cao, J; Deng, J; Li, T; Liang, C; Wei, H; Xiong, W; Xu, L; Yang, S; Yang, Y; Zhang, J; Zhou, Q | 1 |
| Alles, S; Attaix, D; Brajon, B; Leydier, I; Meynial-Denis, D; Mezzarobba, V; Mignon, M; Torrent, A | 1 |
| Brann, DW; De Sevilla, L; Mahesh, VB; Zamorano, PL | 1 |
| Haji, A; Ohi, Y; Takeda, R; Yamazaki, H | 1 |
| Jensen, BL; Madsen, K; Nielsen, FT; Skøtt, O; Stubbe, J | 1 |
| Crocker, A; Joiner, WJ; Sehgal, A; White, BH | 1 |
| Horiuchi, J; Nagano, S; Nakagami, Y; Saitoe, M; Tamura, T; Yamazaki, D | 1 |
| Giannakou, ME; Goss, M; Jacobson, J; Leevers, SJ; Partridge, L; Vinti, G | 1 |
| Ashwell, JD; Papadopoulos, V; Vacchio, MS | 1 |
| Carey, F; Horan, MA; Rothwell, NJ; Strijbos, PJ | 1 |
| Felsner, P; Globerson, A; Hofer, D; Rinner, I; Schauenstein, K | 1 |
| Flynn, NE; Wu, G | 1 |
| Pácha, J; Zemanová, Z | 1 |
| Day, NK; Good, RA; Itoh, Y; Iwabuchi, K; Kizaki, T; Oh-Ishi, S; Ohno, H; Onoé, K; Ookawara, T | 1 |
| Morgan, WW; Richardson, A; Sharp, ZD; Walter, CA | 1 |
| Balter, M | 1 |
| Csaba, G; Inczefi-Gonda, A | 1 |
| Kalish, EE; Logvinenko, NS; Solenov, EI; Svitasheva, NG | 1 |
| Beck, G; Chasserot-Golaz, S; Genot, G; Lechner, MC; Ribeiro, V | 1 |
| Capek, K; Pácha, J; Popp, M | 1 |
1 review(s) available for mifepristone and Aging
| Article | Year |
|---|---|
Application of exogenously regulatable promoter systems to transgenic models for the study of aging.
Topics: Aging; Animals; Disease Models, Animal; Ecdysone; Embryonic and Fetal Development; Gene Expression Regulation; Growth; Homeostasis; Mice; Mice, Knockout; Mice, Transgenic; Mifepristone; Promoter Regions, Genetic; Tetracycline; Transcription, Genetic; Transcriptional Activation | 1999 |
1 trial(s) available for mifepristone and Aging
| Article | Year |
|---|---|
Sleep EEG effects of anti-gluco- and anti-mineralocorticoids in old-aged men: pilot study.
Topics: Aged; Aged, 80 and over; Aging; Electroencephalography; Humans; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Pilot Projects; Receptors, Glucocorticoid; Single-Blind Method; Sleep Stages; Spironolactone | 2014 |
29 other study(ies) available for mifepristone and Aging
| Article | Year |
|---|---|
A living biosensor model to dynamically trace glucocorticoid transcriptional activity during development and adult life in zebrafish.
Topics: Aging; Animals; Animals, Genetically Modified; Biosensing Techniques; Dexamethasone; Gene Expression; Gene Knockdown Techniques; Genes, Reporter; Glucocorticoids; Green Fluorescent Proteins; Microscopy, Fluorescence; Mifepristone; Models, Biological; Morpholinos; Organ Specificity; Receptors, Glucocorticoid; Response Elements; Transcription, Genetic; Transgenes; Zebrafish | 2014 |
Greater glucocorticoid receptor activation in hippocampus of aged rats sensitizes microglia.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Aging; Animals; Catalysis; Cells, Cultured; Corticosterone; Hippocampus; Inflammation; Male; Memory; Memory Disorders; Microglia; Mifepristone; Physical Conditioning, Animal; Rats, Inbred F344; Receptors, Glucocorticoid | 2015 |
Transient mitochondrial DNA double strand breaks in mice cause accelerated aging phenotypes in a ROS-dependent but p53/p21-independent manner.
Topics: Acetylcysteine; Aging; Animals; Apoptosis; Cell Cycle Checkpoints; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Deoxyribonucleases, Type II Site-Specific; DNA Breaks, Double-Stranded; DNA, Mitochondrial; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Mifepristone; Phenotype; Reactive Oxygen Species; Thymocytes; Tumor Suppressor Protein p53 | 2017 |
Developmental reprogramming of rat GLUT5 requires glucocorticoid receptor translocation to the nucleus.
Topics: Active Transport, Cell Nucleus; Aging; Animals; Dexamethasone; Fructose; Gene Expression Regulation, Developmental; Glucose Transporter Type 5; Mifepristone; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid | 2008 |
Characterization of the Drosophila gene-switch system in aging studies: a cautionary tale.
Topics: Aging; Animals; Drosophila melanogaster; Female; Gene Expression Regulation, Developmental; Longevity; Male; Mifepristone; Models, Genetic | 2008 |
Preclinical assessment for selectively disrupting a traumatic memory via postretrieval inhibition of glucocorticoid receptors.
Topics: Aging; Animals; Avoidance Learning; Dose-Response Relationship, Drug; Electroshock; Hormone Antagonists; Male; Memory; Mental Recall; Mifepristone; Motor Activity; Rats; Rats, Long-Evans; Receptors, Glucocorticoid; Stress Disorders, Post-Traumatic; Stress Disorders, Traumatic, Acute; Wounds and Injuries | 2009 |
Postnatal glucocorticoid excess due to pituitary glucocorticoid receptor deficiency: differential short- and long-term consequences.
Topics: Adaptation, Psychological; Aging; Animals; Animals, Newborn; Corticosterone; Corticotropin-Releasing Hormone; Feedback, Physiological; Gene Deletion; Glucocorticoids; Hormone Antagonists; Hypothalamo-Hypophyseal System; Male; Mice; Mice, Knockout; Mifepristone; Models, Animal; Paraventricular Hypothalamic Nucleus; Pituitary Gland; Pituitary-Adrenal System; Receptors, Glucocorticoid; Vasopressins | 2009 |
A screen of apoptosis and senescence regulatory genes for life span effects when over-expressed in Drosophila.
Topics: Aging; Animals; Apoptosis; Drosophila; Female; Gene Expression Regulation; Hormone Antagonists; Larva; Longevity; Male; Mifepristone; Sex Characteristics | 2009 |
Brain aging and Aβ₁₋₄₂ neurotoxicity converge via deterioration in autophagy-lysosomal system: a conditional Drosophila model linking Alzheimer's neurodegeneration with aging.
Topics: Age Factors; Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Autophagy; Brain; Disease Models, Animal; Drosophila; Drosophila Proteins; Gene Expression Regulation; Green Fluorescent Proteins; Hormone Antagonists; Humans; Lysosomes; Microscopy, Confocal; Microscopy, Electron, Transmission; Mifepristone; Neurons; Peptide Fragments | 2011 |
Ageing increases vulnerability to aβ42 toxicity in Drosophila.
Topics: Aging; Amyloid beta-Peptides; Animals; Drosophila melanogaster; Gene Expression Regulation; Mifepristone; Peptide Fragments; RNA, Messenger; Solubility; Time Factors | 2012 |
Both stress experience and age determine the impairment or enhancement effect of stress on spatial memory retrieval.
Topics: Aging; Animals; Hormone Antagonists; Male; Memory Disorders; Mental Recall; Mifepristone; Psychological Tests; Rats; Rats, Wistar; Receptors, Glucocorticoid; Stress, Psychological | 2003 |
The role of adrenal hormones in the response of glutamine synthetase to fasting in adult and old rats.
Topics: Adrenal Glands; Adrenalectomy; Age Factors; Aging; Analysis of Variance; Animals; Blotting, Northern; Fasting; Glucocorticoids; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Hormone Antagonists; Male; Mifepristone; Muscle, Skeletal; Rats; Rats, Wistar; RNA, Messenger | 2003 |
Expression of glutamate receptor subunits in the hypothalamus of the female rat during the afternoon of the proestrous luteinizing hormone surge and effects of antiprogestin treatment and aging.
Topics: Aging; Analysis of Variance; Animals; Blotting, Northern; Blotting, Western; Drug Interactions; Enzyme Inhibitors; Estrogens; Female; Gene Expression Regulation; Hypothalamus; Luteinizing Hormone; Mifepristone; Ovariectomy; Proestrus; Progesterone; Protein Subunits; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors | 2005 |
Effects of progesterone on apneic events during behaviorally defined sleep in male rats.
Topics: Aging; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Antagonism; Hormone Antagonists; Hyperventilation; Injections, Intraperitoneal; Male; Mifepristone; Plethysmography, Whole Body; Progesterone; Rats; Rats, Sprague-Dawley; Respiration; Sleep; Sleep Apnea Syndromes | 2005 |
Glucocorticoid impairs growth of kidney outer medulla and accelerates loop of Henle differentiation and urinary concentrating capacity in rat kidney development.
Topics: Aging; Animals; Animals, Newborn; Cell Differentiation; Dexamethasone; Female; Glucocorticoids; Kidney Medulla; Loop of Henle; Mifepristone; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Urine | 2006 |
Sleep in Drosophila is regulated by adult mushroom bodies.
Topics: Aging; Animals; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Drosophila melanogaster; Female; Gene Expression Regulation, Enzymologic; Homeostasis; Learning; Mifepristone; Models, Animal; Mushroom Bodies; Sleep | 2006 |
The Drosophila DCO mutation suppresses age-related memory impairment without affecting lifespan.
Topics: Aging; Animals; Animals, Genetically Modified; Behavior, Animal; Casein Kinase 1 epsilon; Conditioning, Psychological; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Drosophila; Drosophila Proteins; Enzyme-Linked Immunosorbent Assay; Hormone Antagonists; Memory Disorders; Mifepristone; Mushroom Bodies; Mutation; Odorants; Survival Analysis; Time Factors | 2007 |
Dynamics of the action of dFOXO on adult mortality in Drosophila.
Topics: Aging; Animals; Drosophila melanogaster; Drosophila Proteins; Female; Forkhead Transcription Factors; Gene Expression Regulation; Insulin-Like Growth Factor I; Longevity; Mifepristone; Signal Transduction | 2007 |
Steroid production in the thymus: implications for thymocyte selection.
Topics: Aging; Animals; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Corticosterone; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Epithelial Cells; Epithelium; Fetus; Lymphocyte Depletion; Metyrapone; Mice; Mice, Inbred BALB C; Mifepristone; Organ Culture Techniques; Pregnenolone; Receptors, Antigen, T-Cell; Receptors, Glucocorticoid; Signal Transduction; T-Lymphocytes; Thymus Gland | 1994 |
Impaired febrile responses of aging mice are mediated by endogenous lipocortin-1 (annexin-1).
Topics: Aging; Animals; Annexin A1; Body Temperature; Corticosterone; Dinoprostone; Female; Fever; Immune Sera; Immunoglobulin G; Interleukin-1; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mifepristone; Norepinephrine; Osmolar Concentration; Oxygen Consumption | 1993 |
Characterization of the spontaneous apoptosis of rat thymocytes in vitro.
Topics: Acridine Orange; Adrenalectomy; Aging; Animals; Anti-Inflammatory Agents; Apoptosis; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Count; Cell Survival; Cells, Cultured; Corticosterone; Cycloheximide; DNA Damage; Flow Cytometry; Fluorescent Dyes; Hormone Antagonists; Male; Mifepristone; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Thymus Gland | 1996 |
Glucocorticoids play an important role in mediating the enhanced metabolism of arginine and glutamine in enterocytes of postweaning pigs.
Topics: Aging; Ammonia; Animals; Arginase; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Carbon Dioxide; Cells, Cultured; DNA; Enzyme Induction; Female; Glucocorticoids; Glutamine; Hydrocortisone; Jejunum; Male; Mifepristone; Ornithine; Proline; Receptors, Glucocorticoid; Swine; Urea; Weaning | 1997 |
Localization of Na,K-ATPase activity in developing rat distal colon: role of corticosteroids.
Topics: 4-Nitrophenylphosphatase; Adrenal Cortex Hormones; Adrenalectomy; Aging; Aldosterone; Animals; Colon; Desoxycorticosterone; Dexamethasone; Glucocorticoids; Hormone Antagonists; Intestinal Mucosa; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Ouabain; Rats; Rats, Wistar; Receptors, Glucocorticoid; Sodium-Potassium-Exchanging ATPase; Spironolactone | 1998 |
An increase in basal glucocorticoid concentration with age induces suppressor macrophages with high-density Fc gamma RII/III.
Topics: Aging; Animals; Glucocorticoids; Hormone Antagonists; Immune Tolerance; Macrophage Activation; Macrophage-1 Antigen; Macrophages; Male; Mice; Mice, Inbred BALB C; Mifepristone; Receptors, IgG; Spleen | 1998 |
Profile. For 'father' of abortion drug, vindication at last.
Topics: Abortifacient Agents, Steroidal; Aging; Dehydroepiandrosterone; Drug Approval; Drug Industry; Female; France; History, 20th Century; Humans; Mifepristone; United States; United States Food and Drug Administration | 2000 |
Similarities and dissimilarities of newborn and adolescent rats in the binding capacity of thymic glucocorticoid receptors.
Topics: Aging; Animals; Animals, Newborn; Dexamethasone; Female; Male; Mifepristone; Rats; Rats, Wistar; Receptors, Glucocorticoid; Thymus Gland | 2001 |
[The age-related characteristics of the hormonal regulation of Na+, K(+)-ATPase activity in the kidney cortex of rats].
Topics: Adrenalectomy; Aging; Aldosterone; Animals; Kidney Cortex; Kidney Tubules, Collecting; Kidney Tubules, Distal; Male; Mifepristone; Rats; Rats, Wistar; Receptors, Mineralocorticoid; Sodium-Potassium-Exchanging ATPase; Spironolactone | 1992 |
The steroid antagonist RU38486 is metabolized by the liver microsomal P450 mono-oxygenases.
Topics: Aging; Animals; Antibodies; Biotransformation; Cytochrome P-450 Enzyme System; Kinetics; Liver; Male; Methylcholanthrene; Microsomes, Liver; Mifepristone; Phenobarbital; Rats; Rats, Inbred Strains; Reference Values | 1990 |
Corticosteroid regulation of Na+ and K+ transport in the rat distal colon during postnatal development.
Topics: Adrenal Cortex Hormones; Adrenalectomy; Aging; Aldosterone; Amiloride; Animals; Animals, Suckling; Colon; Corticosterone; Dexamethasone; Estrenes; Mifepristone; Potassium; Rats; Sodium; Spironolactone | 1988 |