Page last updated: 2024-08-23

mifepristone and Acute Post-Traumatic Stress Disorder

mifepristone has been researched along with Acute Post-Traumatic Stress Disorder in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (27.27)29.6817
2010's5 (45.45)24.3611
2020's3 (27.27)2.80

Authors

AuthorsStudies
Baker, DG; Bechard, BW; Bizien, M; Flory, JD; Golier, JA; Hurley, RA; Kimbrell, T; Li, X; Reda, DJ; Yehuda, R1
Barth, J; Bavato, F; Dietrich, AC; Ehring, T; Kleim, B; Meister, L; Offenhammer, B; Rohde, J; Rosi-Andersen, A; Schäfer, I; Seifritz, E; Stefanovic, M1
Chen, X; da Silva, MS; Ding, J; Han, F; Lingeman, J; Meijer, OC1
Akirav, I; Shoshan, N1
Howland, RH1
Fischer, AM; Goetz, JM; Lasko, NB; Marin, MF; Orr, SP; Pitman, RK; Rosasco, ML; Spring, JD; Suris, AM; Wood, NE1
Caramanica, K; Golier, JA; Harvey, PD; Makotkine, I; Michaelides, AC; Schmeidler, J; Yehuda, R1
Alberini, CM; New, AS; Riceberg, JS; Taubenfeld, SM1
Cohen, H; Cohen, S; Kaplan, Z; Kozlovsky, N; Matar, MA; Zohar, J1
Adamec, R; Grimes, M; Muir, C; Pearcey, K1
Harada, K; Hoshino, A; Kato, K; Kato, N; Kohda, K; Matsuoka, N; Morinobu, S; Motohashi, J; Yamaji, T1

Reviews

2 review(s) available for mifepristone and Acute Post-Traumatic Stress Disorder

ArticleYear
Pharmacological memory modulation to augment trauma-focused psychotherapy for PTSD: a systematic review of randomised controlled trials.
    Translational psychiatry, 2023, Jun-15, Volume: 13, Issue:1

    Topics: Cycloserine; Dexamethasone; Humans; Mifepristone; Propranolol; Psychotherapy; Randomized Controlled Trials as Topic; Stress Disorders, Post-Traumatic

2023
Mifepristone as a therapeutic agent in psychiatry.
    Journal of psychosocial nursing and mental health services, 2013, Volume: 51, Issue:6

    Topics: Affective Disorders, Psychotic; Alcoholism; Antipsychotic Agents; Clinical Trials as Topic; Cocaine-Related Disorders; Hormone Antagonists; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Mental Disorders; Mifepristone; Pituitary-Adrenal System; Psychotic Disorders; Stress Disorders, Post-Traumatic; Weight Gain

2013

Trials

3 trial(s) available for mifepristone and Acute Post-Traumatic Stress Disorder

ArticleYear
Efficacy and Safety of Mifepristone in the Treatment of Male US Veterans With Posttraumatic Stress Disorder: A Phase 2a Randomized Clinical Trial.
    JAMA network open, 2023, 05-01, Volume: 6, Issue:5

    Topics: Adult; Blindness; Brain Injuries, Traumatic; Female; Gallopamil; Humans; Male; Mifepristone; Stress Disorders, Post-Traumatic; United States; Veterans

2023
Pharmacological blockade of memory reconsolidation in posttraumatic stress disorder: three negative psychophysiological studies.
    Psychiatry research, 2015, Jan-30, Volume: 225, Issue:1-2

    Topics: Adrenergic beta-Antagonists; Adult; Arousal; Combat Disorders; Double-Blind Method; Emotions; Female; Heart Rate; Humans; Imagination; Male; Mental Recall; Middle Aged; Mifepristone; Propranolol; Receptors, Glucocorticoid; Stress Disorders, Post-Traumatic; Veterans; Young Adult

2015
A randomized, double-blind, placebo-controlled, crossover trial of mifepristone in Gulf War veterans with chronic multisymptom illness.
    Psychoneuroendocrinology, 2016, Volume: 64

    Topics: Adult; Chronic Disease; Cognition; Cross-Over Studies; Depression; Dexamethasone; Double-Blind Method; Fatigue; Female; Gulf War; Health Status; Humans; Hydrocortisone; Male; Middle Aged; Mifepristone; Pituitary-Adrenal Function Tests; Receptors, Glucocorticoid; Stress Disorders, Post-Traumatic; Veterans

2016

Other Studies

6 other study(ies) available for mifepristone and Acute Post-Traumatic Stress Disorder

ArticleYear
Effects of RU486 treatment after single prolonged stress depend on the post-stress interval.
    Molecular and cellular neurosciences, 2020, Volume: 108

    Topics: Animals; Brain; DNA Methylation; Drug Administration Schedule; Hormone Antagonists; Male; Mifepristone; Rats; Rats, Wistar; Receptors, Glucocorticoid; Stress Disorders, Post-Traumatic; Tacrolimus Binding Proteins

2020
The effects of cannabinoid receptors activation and glucocorticoid receptors deactivation in the amygdala and hippocampus on the consolidation of a traumatic event.
    Neurobiology of learning and memory, 2017, Volume: 144

    Topics: Amygdala; Animals; Benzoxazines; Disease Models, Animal; Electroshock; Extinction, Psychological; Fear; Hippocampus; Male; Memory Consolidation; Mental Recall; Mifepristone; Morpholines; Naphthalenes; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptors, Glucocorticoid; Reflex, Startle; Stress Disorders, Post-Traumatic

2017
Preclinical assessment for selectively disrupting a traumatic memory via postretrieval inhibition of glucocorticoid receptors.
    Biological psychiatry, 2009, Feb-01, Volume: 65, Issue:3

    Topics: Aging; Animals; Avoidance Learning; Dose-Response Relationship, Drug; Electroshock; Hormone Antagonists; Male; Memory; Mental Recall; Mifepristone; Motor Activity; Rats; Rats, Long-Evans; Receptors, Glucocorticoid; Stress Disorders, Post-Traumatic; Stress Disorders, Traumatic, Acute; Wounds and Injuries

2009
Post-exposure sleep deprivation facilitates correctly timed interactions between glucocorticoid and adrenergic systems, which attenuate traumatic stress responses.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:11

    Topics: Acoustic Stimulation; Adrenergic Agonists; Analysis of Variance; Animals; Corticosterone; Dendrites; Disease Models, Animal; Electrocardiography; Epinephrine; Freezing Reaction, Cataleptic; Gene Expression Regulation; Heart Rate; Hippocampus; Hormone Antagonists; Male; Maze Learning; Mifepristone; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Reflex, Startle; Silver Staining; Sleep Deprivation; Stress Disorders, Post-Traumatic; Telemetry; Time Factors

2012
Involvement of noradrenergic and corticoid receptors in the consolidation of the lasting anxiogenic effects of predator stress.
    Behavioural brain research, 2007, May-16, Volume: 179, Issue:2

    Topics: Adrenergic beta-Antagonists; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Association Learning; Chi-Square Distribution; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Propranolol; Random Allocation; Rats; Receptors, Adrenergic, beta; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Reflex, Startle; Statistics, Nonparametric; Stress Disorders, Post-Traumatic; Stress, Psychological

2007
Glucocorticoid receptor activation is involved in producing abnormal phenotypes of single-prolonged stress rats: a putative post-traumatic stress disorder model.
    Neuroscience, 2007, Aug-10, Volume: 148, Issue:1

    Topics: Amygdala; Animals; Anxiety Disorders; Avoidance Learning; Cell Death; Corticosterone; Disease Models, Animal; Fear; Hippocampus; Hypothalamo-Hypophyseal System; Long-Term Potentiation; Male; Memory; Memory Disorders; Mifepristone; Nerve Degeneration; Phenotype; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Reflex, Abnormal; Reflex, Startle; Stress Disorders, Post-Traumatic; Stress, Psychological

2007