Page last updated: 2024-08-23

mifepristone and Acute Liver Injury, Drug-Induced

mifepristone has been researched along with Acute Liver Injury, Drug-Induced in 14 studies

Research

Studies (14)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (7.14)	18.2507
2000's	2 (14.29)	29.6817
2010's	10 (71.43)	24.3611
2020's	1 (7.14)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Ding, D; Fang, H; Kelly, R; Liu, Z; Shi, Q; Tong, W	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Ault, TA; Braxton, DR; Fong, TL; Marcus, AO; Watson, RA	1
Funke, K; Rockey, DC	1
Fan, TT; Han, ZP; Hao, C; Li, L; Shi, YF; Wei, LX; Yang, X; Yang, Y; Zhang, SS; Zhu, PX	1
Ho, RJ; Jia, L; Li, T; Liu, J; Tu, X; Wan, L; Wang, J; Xiao, Y; Xu, H; Yan, C; Yang, X; Yu, S; Zhu, Y	1
Bu, P; Cheng, X; Le, Y; Vispute, SG	1
Egawa, T; Horiguchi, M; Kaji, H; Kim, J; Koyanagi, S; Makino, K; Matsunaga, N; Ohdo, S	1
Bourdi, M; Carpenter, LD; Collins, LA; Graf, ML; Masson, MJ; Pohl, LR; Ryan, PM	1
Hernández-Alcoceba, R; Kochanek, S; Kramer, MG; Prieto, J; Qian, C; Sangro, B; Shankar, V; Wang, L; Zabala, M	1
Dong, A; Hu, J; Liu, X; Xu, H; Zhao, L	1
Appleyard, C; Le, T; Swain, MG; Wallace, J; Wong, H	1

Reviews

2 review(s) available for mifepristone and Acute Liver Injury, Drug-Induced

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Mifepristone induced liver injury in a patient with Cushing syndrome: a case report and review of the literature. Journal of medical case reports, 2023, Feb-03, Volume: 17, Issue:1 Topics: Abortion, Induced; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Cholestasis; Cushing Syndrome; Female; Humans; Middle Aged; Mifepristone; Pregnancy	2023

Other Studies

12 other study(ies) available for mifepristone and Acute Liver Injury, Drug-Induced

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS computational biology, 2011, Volume: 7, Issue:12 Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Models, Biological; Predictive Value of Tests	2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Cholestatic Drug-Induced Liver Injury Caused by Mifepristone. Hepatology (Baltimore, Md.), 2019, Volume: 69, Issue:6 Topics: Aged; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Cushing Syndrome; Female; Humans; Mifepristone	2019
Chronic restraint stress decreases the repair potential from mesenchymal stem cells on liver injury by inhibiting TGF-β1 generation. Cell death & disease, 2014, Jun-26, Volume: 5 Topics: Allografts; Animals; Anti-Inflammatory Agents; Carbon Tetrachloride Poisoning; Cell Differentiation; Chemical and Drug Induced Liver Injury; Chronic Disease; Corticosterone; Gene Expression Regulation; Hormone Antagonists; Liver Cirrhosis; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Transgenic; Mifepristone; Restraint, Physical; Signal Transduction; Smad Proteins; Stress, Physiological; Transforming Growth Factor beta1	2014
Thirty-day rat toxicity study reveals reversible liver toxicity of mifepristone (RU486) and metapristone. Toxicology mechanisms and methods, 2016, Volume: 26, Issue:1 Topics: Abortifacient Agents, Steroidal; Animals; Chemical and Drug Induced Liver Injury; Female; Male; Mifepristone; Rats	2016
Activation of GR but not PXR by dexamethasone attenuated acetaminophen hepatotoxicities via Fgf21 induction. Toxicology, 2017, 03-01, Volume: 378 Topics: Acetaminophen; Animals; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP3A; Dexamethasone; Fibroblast Growth Factors; Glutathione; Humans; Liver; Male; Membrane Proteins; Mice, Inbred C57BL; Mice, Knockout; Mifepristone; Pregnane X Receptor; Receptors, Glucocorticoid; Receptors, Steroid; RNA, Messenger	2017
Glucocorticoid-dependent expression of O(6)-methylguanine-DNA methyltransferase gene modulates dacarbazine-induced hepatotoxicity in mice. The Journal of pharmacology and experimental therapeutics, 2010, Volume: 333, Issue:3 Topics: Adrenalectomy; Animals; Antineoplastic Agents; Cells, Cultured; Chemical and Drug Induced Liver Injury; Circadian Rhythm; Corticosterone; Dacarbazine; Dose-Response Relationship, Drug; Glucocorticoids; Hormone Antagonists; Male; Mice; Mice, Inbred ICR; Mifepristone; O(6)-Methylguanine-DNA Methyltransferase; Reverse Transcriptase Polymerase Chain Reaction	2010
Pathologic role of stressed-induced glucocorticoids in drug-induced liver injury in mice. Biochemical and biophysical research communications, 2010, Jul-02, Volume: 397, Issue:3 Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Corticosterone; Dexamethasone; Female; Glucocorticoids; Liver; Male; Mice; Mice, Inbred C57BL; Mifepristone; Receptors, Glucocorticoid; Stress, Physiological	2010
Prolonged and inducible transgene expression in the liver using gutless adenovirus: a potential therapy for liver cancer. Gastroenterology, 2004, Volume: 126, Issue:1 Topics: Adenoviridae; Animals; Antineoplastic Agents; Cell Line; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Gene Expression; Genetic Therapy; Genetic Vectors; Humans; Interleukin-12; Kinetics; Liver; Liver Neoplasms; Mice; Mice, Inbred C57BL; Mifepristone; Recombinant Proteins; Tissue Distribution; Trans-Activators; Transgenes	2004
Regulation and pharmacokinetics of inducible recombinant TRAIL expression. Cancer biology & therapy, 2007, Volume: 6, Issue:12 Topics: Adenocarcinoma; Adenoviridae; Amino Acid Sequence; Animals; Apoptosis; Base Sequence; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; Genes, Synthetic; Genetic Vectors; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Mifepristone; Molecular Sequence Data; Promoter Regions, Genetic; Protein Structure, Tertiary; Recombinant Fusion Proteins; TNF-Related Apoptosis-Inducing Ligand; Xenograft Model Antitumor Assays	2007
Endogenous glucocorticoids released during acute toxic liver injury enhance hepatic IL-10 synthesis and release. The American journal of physiology, 1999, Volume: 276, Issue:1 Topics: Acute Disease; Adrenalectomy; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Corticosterone; Glucocorticoids; Hormone Antagonists; Interleukin-10; Liver; Liver Diseases; Male; Mifepristone; Rats; Rats, Sprague-Dawley; RNA, Messenger; Survival Analysis; Tumor Necrosis Factor-alpha	1999