Page last updated: 2024-08-23

mifepristone and Acute Confusional Senile Dementia

mifepristone has been researched along with Acute Confusional Senile Dementia in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (41.67)29.6817
2010's7 (58.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, D; Huang, R; Li, W; Wang, Y; Xu, T; Yin, Y; Zhang, B; Zhang, J; Zhang, Y1
O'Banion, MK1
Barik, J; Bethus, I; Chafai, M; Kootar, S; Lanté, F; Marie, H; Mouska, X; Pereira, AR; Raymond, EF1
Belanoff, JK; Canet, G; Chevallier, N; Desrumaux, C; Givalois, L; Hunt, H; Ollivier, M; Pineau, F1
Ling, D; Salvaterra, PM1
Chen, L; Fuchs, PM; Kanazirska, MV; Lal, S; Vassilev, PM; Verma, J1
Baglietto-Vargas, D; Green, KN; LaFerla, FM; Martinez-Coria, H; Medeiros, R1
Belanoff, J; DeBattista, C1
Cooper, TB; de la Pena, CB; Ferris, S; Hernando, RT; Pomara, N; Sidtis, JJ1
Anand, KS; Dhikav, V1
Lam, FC; Liu, R; Lu, P; Reiner, PB; Renoir, JM; Shapiro, AB; Sharom, FJ1
Doraiswamy, PM; Ferris, S; Pomara, N; Tun, H1

Reviews

1 review(s) available for mifepristone and Acute Confusional Senile Dementia

ArticleYear
C-1073 (mifepristone) in the adjunctive treatment of Alzheimer's disease.
    Current Alzheimer research, 2005, Volume: 2, Issue:2

    Topics: Alzheimer Disease; Clinical Trials as Topic; Cognition Disorders; Drug Therapy, Combination; Humans; Mifepristone; Receptors, Glucocorticoid

2005

Trials

2 trial(s) available for mifepristone and Acute Confusional Senile Dementia

ArticleYear
The effect of mifepristone (RU 486) on plasma cortisol in Alzheimer's disease.
    Neurochemical research, 2006, Volume: 31, Issue:5

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Dexamethasone; Double-Blind Method; Female; Glucocorticoids; Hormone Antagonists; Humans; Hydrocortisone; Male; Middle Aged; Mifepristone; Placebos; Prospective Studies; Receptors, Glucocorticoid

2006
Mifepristone (RU 486) for Alzheimer's disease.
    Neurology, 2002, May-14, Volume: 58, Issue:9

    Topics: Aged; Alzheimer Disease; Anorexia; Cognition; Double-Blind Method; Drug Eruptions; Fatigue; Female; Headache; Hormone Antagonists; Humans; Hypokalemia; Male; Mifepristone; Neuropsychological Tests; Pilot Projects; Receptors, Glucocorticoid; Treatment Outcome

2002

Other Studies

9 other study(ies) available for mifepristone and Acute Confusional Senile Dementia

ArticleYear
Chronic dexamethasone treatment results in hippocampal neurons injury due to activate NLRP1 inflammasome in vitro.
    International immunopharmacology, 2017, Volume: 49

    Topics: Adaptor Proteins, Signal Transducing; Alzheimer Disease; Animals; Apoptosis Regulatory Proteins; Cell Death; Cells, Cultured; Dexamethasone; Hippocampus; Humans; Inflammasomes; Long Term Adverse Effects; Mifepristone; Neurogenic Inflammation; Neurons; NF-kappa B; NLR Proteins; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid

2017
It may take more than a shot: alternatives to immunotherapy for Alzheimer's disease.
    Biological psychiatry, 2013, Sep-01, Volume: 74, Issue:5

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Hormone Antagonists; Humans; Immunotherapy; Male; Mifepristone; tau Proteins

2013
Subchronic glucocorticoid receptor inhibition rescues early episodic memory and synaptic plasticity deficits in a mouse model of Alzheimer's disease.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015, Volume: 40, Issue:7

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Dexamethasone; Disease Models, Animal; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glucocorticoids; Hippocampus; Hormone Antagonists; Humans; Memory Disorders; Memory, Episodic; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mifepristone; Mutation; Neuronal Plasticity; Quinoxalines; Receptors, Glucocorticoid; Recognition, Psychology; Valine

2015
New selective glucocorticoid receptor modulators reverse amyloid-β peptide-induced hippocampus toxicity.
    Neurobiology of aging, 2016, Volume: 45

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Aza Compounds; Cognitive Dysfunction; Disease Models, Animal; Dose-Response Relationship, Drug; Glucocorticoids; Heterocyclic Compounds, 4 or More Rings; Hippocampus; Hypothalamo-Hypophyseal System; Isoquinolines; Male; Mifepristone; Molecular Targeted Therapy; Pituitary-Adrenal System; Pyrazoles; Rats, Sprague-Dawley; Receptors, Glucocorticoid

2016
Brain aging and Aβ₁₋₄₂ neurotoxicity converge via deterioration in autophagy-lysosomal system: a conditional Drosophila model linking Alzheimer's neurodegeneration with aging.
    Acta neuropathologica, 2011, Volume: 121, Issue:2

    Topics: Age Factors; Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Autophagy; Brain; Disease Models, Animal; Drosophila; Drosophila Proteins; Gene Expression Regulation; Green Fluorescent Proteins; Hormone Antagonists; Humans; Lysosomes; Microscopy, Confocal; Microscopy, Electron, Transmission; Mifepristone; Neurons; Peptide Fragments

2011
Beneficial effects of lysosome-modulating and other pharmacological and nanocarrier agents on amyloid-beta-treated cells.
    Current pharmaceutical biotechnology, 2012, Volume: 13, Issue:15

    Topics: Acetylcarnitine; Alzheimer Disease; Amyloid beta-Peptides; Cell Line, Tumor; Cell Survival; Drug Carriers; Endosomes; Humans; Kaempferols; Lactic Acid; Lysosomes; Memantine; Mifepristone; Nanoparticles; Neuroprotective Agents; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Resveratrol; Stilbenes

2012
Mifepristone alters amyloid precursor protein processing to preclude amyloid beta and also reduces tau pathology.
    Biological psychiatry, 2013, Sep-01, Volume: 74, Issue:5

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; CREB-Binding Protein; Hormone Antagonists; Male; Maze Learning; Mice; Mice, Transgenic; Mifepristone; tau Proteins

2013
Glucocorticoids may initiate Alzheimer's disease: a potential therapeutic role for mifepristone (RU-486).
    Medical hypotheses, 2007, Volume: 68, Issue:5

    Topics: Alzheimer Disease; Glucocorticoids; Humans; Mifepristone; Models, Biological

2007
beta-Amyloid efflux mediated by p-glycoprotein.
    Journal of neurochemistry, 2001, Volume: 76, Issue:4

    Topics: Adenosine Triphosphate; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Anilino Naphthalenesulfonates; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Cell Line; Cell Membrane; Cricetinae; Humans; Kidney; Mifepristone; Mutation; Peptide Fragments; Secretory Vesicles; Transfection

2001