midodrine has been researched along with Urinary Incontinence, Stress in 12 studies
Midodrine: An ethanolamine derivative that is an adrenergic alpha-1 agonist. It is used as a vasoconstrictor agent in the treatment of HYPOTENSION.
midodrine : An aromatic ether that is 1,4-dimethoxybenzene which is substituted at position 2 by a 2-(glycylamino)-1-hydroxyethyl group. A direct-acting sympathomimetic with selective alpha-adrenergic agonist activity, it is used (generally as its hydrochloride salt) as a peripheral vasoconstrictor in the treatment of certain hypotensive states. The main active moiety is its major metabolite, deglymidodrine.
Urinary Incontinence, Stress: Involuntary discharge of URINE as a result of physical activities that increase abdominal pressure on the URINARY BLADDER without detrusor contraction or overdistended bladder. The subtypes are classified by the degree of leakage, descent and opening of the bladder neck and URETHRA without bladder contraction, and sphincter deficiency.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Midodrine is a potent and selective alpha1-receptor agonist and its potential to increase urethral closure pressure could be useful in the treatment of female stress incontinence." | 2.69 | Randomized double-blind placebo-controlled multicenter evaluation of efficacy and dose finding of midodrine hydrochloride in women with mild to moderate stress urinary incontinence: a phase II study. ( Abbühl, BE; Dijkman, GA; Eerdmans, PH; Egarter, C; Feyereisl, J; Heidler, H; Kölle, D; Plasman, JE; Schmidbauer, C; Tamussino, K; Vierhout, ME; Weil, EH; Wein, W, 1998) |
| "Adrenergic drugs have been used for the treatment of urinary incontinence." | 2.43 | Adrenergic drugs for urinary incontinence in adults. ( Alhasso, A; Glazener, CM; N'dow, J; Pickard, R, 2005) |
| "Adrenergic drugs have been used for the treatment of urinary incontinence." | 2.42 | Adrenergic drugs for urinary incontinence in adults. ( Alhasso, A; Glazener, CM; N'Dow, J; Pickard, R, 2003) |
| "When midodrine was given to 13 female patients with stress incontinence in the doses 2." | 1.27 | The effect of midodrine and its active metabolite ST 1059 on the human urethra in vitro and in vivo. ( Andersson, KE; Ekman, G; Henriksson, L; Ulmsten, U, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (58.33) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Y | 1 |
| Zhishun, L | 1 |
| Peng, W | 1 |
| Zhao, J | 1 |
| Liu, B | 1 |
| Alhasso, A | 2 |
| Glazener, CM | 2 |
| Pickard, R | 2 |
| N'Dow, J | 2 |
| Thüroff, JW | 1 |
| Frohneberg, D | 1 |
| Petri, E | 1 |
| Jonas, U | 1 |
| Riccabona, M | 1 |
| Kiesswetter, H | 1 |
| Hennrich, F | 1 |
| Englisch, M | 1 |
| Andersson, KE | 1 |
| Ekman, G | 1 |
| Henriksson, L | 1 |
| Ulmsten, U | 1 |
| Gnad, H | 1 |
| Burmucic, R | 1 |
| Petritsch, P | 1 |
| Steindorfer, P | 1 |
| Nito, H | 1 |
| Weil, EH | 1 |
| Eerdmans, PH | 1 |
| Dijkman, GA | 1 |
| Tamussino, K | 1 |
| Feyereisl, J | 1 |
| Vierhout, ME | 1 |
| Schmidbauer, C | 1 |
| Egarter, C | 1 |
| Kölle, D | 1 |
| Plasman, JE | 1 |
| Heidler, H | 1 |
| Abbühl, BE | 1 |
| Wein, W | 1 |
| Jonas, D | 1 |
| Garofalo, F | 1 |
| Lalanne, GM | 1 |
| Nanni, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Integrated Optimization Schemes for Female Stress Incontinence[NCT05053373] | 358 participants (Actual) | Interventional | 2014-05-20 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for midodrine and Urinary Incontinence, Stress
| Article | Year |
|---|---|
Acupuncture for stress urinary incontinence in adults.
Topics: Acupuncture Therapy; Adrenergic alpha-1 Receptor Agonists; Adult; Female; Humans; Midodrine; Randomi | 2013 |
Adrenergic drugs for urinary incontinence in adults.
Topics: Adrenergic Agonists; Adult; Clenbuterol; Female; Humans; Midodrine; Phenylpropanolamine; Randomized | 2003 |
Adrenergic drugs for urinary incontinence in adults.
Topics: Adrenergic Agonists; Adult; Clenbuterol; Female; Humans; Midodrine; Phenylpropanolamine; Randomized | 2005 |
2 trials available for midodrine and Urinary Incontinence, Stress
| Article | Year |
|---|---|
[Conservative therapy of female stress incontinence. Double-blind study with the alpha-sympathomimetic midodrin].
Topics: Adult; Blood Pressure; Double-Blind Method; Ethanolamines; Female; Humans; Middle Aged; Midodrine; U | 1984 |
Randomized double-blind placebo-controlled multicenter evaluation of efficacy and dose finding of midodrine hydrochloride in women with mild to moderate stress urinary incontinence: a phase II study.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Dose-Response Relationship, Drug; Double-Blind Method; Drug | 1998 |
7 other studies available for midodrine and Urinary Incontinence, Stress
| Article | Year |
|---|---|
[Therapy of irritable bladder and urinary incontinence].
Topics: Emepronium; Estriol; Female; Flavoxate; Humans; Midodrine; Quaternary Ammonium Compounds; Urinary Bl | 1981 |
[The conservative treatment of stress incontinence in women with midodrine].
Topics: Adult; Aged; Ethanolamines; Female; Humans; Middle Aged; Midodrine; Postoperative Complications; Uri | 1981 |
Clinical and urodynamic assessment of pharmacologic therapy of stress incontinence.
Topics: Adult; Aged; Drug Therapy, Combination; Estriol; Female; Humans; Imipramine; Middle Aged; Midodrine; | 1983 |
The effect of midodrine and its active metabolite ST 1059 on the human urethra in vitro and in vivo.
Topics: Adult; Aged; Ethanolamines; Female; Humans; In Vitro Techniques; Male; Middle Aged; Midodrine; Norep | 1983 |
[Clinical effect of midodrine hydrochloride on the patients with urinary incontinence].
Topics: Administration, Oral; Adult; Aged; Drug Administration Schedule; Drug Evaluation; Female; Humans; Ma | 1994 |
Treatment of female stress incontinence with midodrine: preliminary report.
Topics: Adrenergic alpha-Agonists; Ethanolamines; Female; Humans; Male; Middle Aged; Midodrine; Pressure; Ur | 1977 |
Midodrine for female incontinence: a preliminary report.
Topics: Adult; Ethanolamines; Female; Humans; Middle Aged; Midodrine; Urethra; Urinary Incontinence, Stress | 1986 |