midodrine and Paralysis, Legs studies

midodrine and Paralysis, Legs

midodrine has been researched along with Paralysis, Legs in 2 studies

Midodrine: An ethanolamine derivative that is an adrenergic alpha-1 agonist. It is used as a vasoconstrictor agent in the treatment of HYPOTENSION.
midodrine : An aromatic ether that is 1,4-dimethoxybenzene which is substituted at position 2 by a 2-(glycylamino)-1-hydroxyethyl group. A direct-acting sympathomimetic with selective alpha-adrenergic agonist activity, it is used (generally as its hydrochloride salt) as a peripheral vasoconstrictor in the treatment of certain hypotensive states. The main active moiety is its major metabolite, deglymidodrine.

Research Excerpts

Excerpt	Relevance	Reference
"This led to successfully oral treatment of the orthostatic hypotension with clonidine 150 micrograms bd and midodrine 10 mg bd."	1.28	Pharmacological evidence of alpha 1- and alpha 2-adrenergic supersensitivity in orthostatic hypotension due to spinal cord injury: a case report. ( Arias, A; Berlan, M; Montastruc, JL; Rascol, A; Senard, JM; Tran, MA, 1991)

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

1 (50.00)

18.2507

2000's

1 (50.00)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Krassioukov, A	1
Eng, JJ	1
Warburton, DE	1
Teasell, R	1
Senard, JM	1
Arias, A	1
Berlan, M	1
Tran, MA	1
Rascol, A	1
Montastruc, JL	1

Studies

Krassioukov, A

Eng, JJ

Warburton, DE

Teasell, R

Senard, JM

Arias, A

Berlan, M

Tran, MA

Rascol, A

Montastruc, JL

Clinical Trials (5)

Trial Overview

Trial	Phase	Enrollment	Study Type	Start Date	Status
Study on Preliminary Safety and Efficacy of the ARC Therapy Using the ARC-IM Lumbar System to Support Mobility in People With Chronic Spinal Cord Injury[NCT05942339]		8 participants (Anticipated)	Interventional	2023-08-31	Not yet recruiting
Restoring Hemodynamic Stability Using Targeted Epidural Spinal Stimulation Following Spinal Cord Injury[NCT04994886]		8 participants (Anticipated)	Interventional	2021-06-08	Recruiting
Dose Response to the Norepinephrine Precursor Droxidopa in Hypotensive Individuals With Spinal Cord Injury[NCT03602014]	Phase 4	22 participants (Actual)	Interventional	2018-06-01	Completed
The Effects of Spinal Cord Stimulation on Autonomic Function in People With Spinal Cord Injury[NCT03924388]		46 participants (Anticipated)	Interventional	2020-02-01	Not yet recruiting
Restoring Hemodynamic Stability Using Targeted Epidural Spinal Stimulation Following Spinal Cord Injury[NCT05044923]		8 participants (Anticipated)	Interventional	2021-12-31	Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial

Phase

Enrollment

Study Type

Start Date

Status

Study on Preliminary Safety and Efficacy of the ARC Therapy Using the ARC-IM Lumbar System to Support Mobility in People With Chronic Spinal Cord Injury[NCT05942339]

8 participants (Anticipated)

Interventional

2023-08-31

Not yet recruiting

Restoring Hemodynamic Stability Using Targeted Epidural Spinal Stimulation Following Spinal Cord Injury[NCT04994886]

8 participants (Anticipated)

Interventional

2021-06-08

Recruiting

Dose Response to the Norepinephrine Precursor Droxidopa in Hypotensive Individuals With Spinal Cord Injury[NCT03602014]

Phase 4

22 participants (Actual)

Interventional

2018-06-01

Completed

The Effects of Spinal Cord Stimulation on Autonomic Function in People With Spinal Cord Injury[NCT03924388]

46 participants (Anticipated)

Interventional

2020-02-01

Not yet recruiting

Restoring Hemodynamic Stability Using Targeted Epidural Spinal Stimulation Following Spinal Cord Injury[NCT05044923]

8 participants (Anticipated)

Interventional

2021-12-31

Recruiting

[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for midodrine and Paralysis, Legs

Article	Year
A systematic review of the management of orthostatic hypotension after spinal cord injury. Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5 Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever	2009
A systematic review of the management of orthostatic hypotension after spinal cord injury. Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5 Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever	2009
A systematic review of the management of orthostatic hypotension after spinal cord injury. Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5 Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever	2009
A systematic review of the management of orthostatic hypotension after spinal cord injury. Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5 Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever	2009
A systematic review of the management of orthostatic hypotension after spinal cord injury. Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5 Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever	2009
A systematic review of the management of orthostatic hypotension after spinal cord injury. Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5 Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever	2009
A systematic review of the management of orthostatic hypotension after spinal cord injury. Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5 Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever	2009
A systematic review of the management of orthostatic hypotension after spinal cord injury. Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5 Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever	2009
A systematic review of the management of orthostatic hypotension after spinal cord injury. Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5 Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever	2009
A systematic review of the management of orthostatic hypotension after spinal cord injury. Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5 Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever	2009
A systematic review of the management of orthostatic hypotension after spinal cord injury. Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5 Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever	2009
A systematic review of the management of orthostatic hypotension after spinal cord injury. Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5 Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever	2009
A systematic review of the management of orthostatic hypotension after spinal cord injury. Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5 Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever	2009
A systematic review of the management of orthostatic hypotension after spinal cord injury. Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5 Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever	2009
A systematic review of the management of orthostatic hypotension after spinal cord injury. Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5 Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever	2009
A systematic review of the management of orthostatic hypotension after spinal cord injury. Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5 Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever	2009
A systematic review of the management of orthostatic hypotension after spinal cord injury. Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5 Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever	2009
A systematic review of the management of orthostatic hypotension after spinal cord injury. Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5 Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever	2009
A systematic review of the management of orthostatic hypotension after spinal cord injury. Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5 Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever	2009
A systematic review of the management of orthostatic hypotension after spinal cord injury. Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5 Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever	2009
A systematic review of the management of orthostatic hypotension after spinal cord injury. Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5 Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever	2009
A systematic review of the management of orthostatic hypotension after spinal cord injury. Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5 Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever	2009
A systematic review of the management of orthostatic hypotension after spinal cord injury. Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5 Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever	2009
A systematic review of the management of orthostatic hypotension after spinal cord injury. Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5 Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever	2009
A systematic review of the management of orthostatic hypotension after spinal cord injury. Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5 Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever	2009

Article

Year

A systematic review of the management of orthostatic hypotension after spinal cord injury.