Page last updated: 2024-10-31

midodrine and Paralysis, Legs

midodrine has been researched along with Paralysis, Legs in 2 studies

Midodrine: An ethanolamine derivative that is an adrenergic alpha-1 agonist. It is used as a vasoconstrictor agent in the treatment of HYPOTENSION.
midodrine : An aromatic ether that is 1,4-dimethoxybenzene which is substituted at position 2 by a 2-(glycylamino)-1-hydroxyethyl group. A direct-acting sympathomimetic with selective alpha-adrenergic agonist activity, it is used (generally as its hydrochloride salt) as a peripheral vasoconstrictor in the treatment of certain hypotensive states. The main active moiety is its major metabolite, deglymidodrine.

Research Excerpts

ExcerptRelevanceReference
"This led to successfully oral treatment of the orthostatic hypotension with clonidine 150 micrograms bd and midodrine 10 mg bd."1.28Pharmacological evidence of alpha 1- and alpha 2-adrenergic supersensitivity in orthostatic hypotension due to spinal cord injury: a case report. ( Arias, A; Berlan, M; Montastruc, JL; Rascol, A; Senard, JM; Tran, MA, 1991)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Krassioukov, A1
Eng, JJ1
Warburton, DE1
Teasell, R1
Senard, JM1
Arias, A1
Berlan, M1
Tran, MA1
Rascol, A1
Montastruc, JL1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Study on Preliminary Safety and Efficacy of the ARC Therapy Using the ARC-IM Lumbar System to Support Mobility in People With Chronic Spinal Cord Injury[NCT05942339]8 participants (Anticipated)Interventional2023-08-31Not yet recruiting
Restoring Hemodynamic Stability Using Targeted Epidural Spinal Stimulation Following Spinal Cord Injury[NCT04994886]8 participants (Anticipated)Interventional2021-06-08Recruiting
Dose Response to the Norepinephrine Precursor Droxidopa in Hypotensive Individuals With Spinal Cord Injury[NCT03602014]Phase 422 participants (Actual)Interventional2018-06-01Completed
The Effects of Spinal Cord Stimulation on Autonomic Function in People With Spinal Cord Injury[NCT03924388]46 participants (Anticipated)Interventional2020-02-01Not yet recruiting
Restoring Hemodynamic Stability Using Targeted Epidural Spinal Stimulation Following Spinal Cord Injury[NCT05044923]8 participants (Anticipated)Interventional2021-12-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for midodrine and Paralysis, Legs

ArticleYear
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009

Other Studies

1 other study available for midodrine and Paralysis, Legs

ArticleYear
Pharmacological evidence of alpha 1- and alpha 2-adrenergic supersensitivity in orthostatic hypotension due to spinal cord injury: a case report.
    European journal of clinical pharmacology, 1991, Volume: 41, Issue:6

    Topics: Blood Pressure; Chronic Disease; Clonidine; Efferent Pathways; Humans; Hypotension, Orthostatic; Mal

1991