Page last updated: 2024-10-31

midodrine and Injuries, Spinal Cord

midodrine has been researched along with Injuries, Spinal Cord in 21 studies

Midodrine: An ethanolamine derivative that is an adrenergic alpha-1 agonist. It is used as a vasoconstrictor agent in the treatment of HYPOTENSION.
midodrine : An aromatic ether that is 1,4-dimethoxybenzene which is substituted at position 2 by a 2-(glycylamino)-1-hydroxyethyl group. A direct-acting sympathomimetic with selective alpha-adrenergic agonist activity, it is used (generally as its hydrochloride salt) as a peripheral vasoconstrictor in the treatment of certain hypotensive states. The main active moiety is its major metabolite, deglymidodrine.

Research Excerpts

ExcerptRelevanceReference
"We evaluated midodrine as oral treatment for pharmacologically induced priapism in spinal cord injured patients."7.75Oral midodrine for prostaglandin e1 induced priapism in spinal cord injured patients. ( Mieusset, R; Plante, P; Previnaire, JG; Soler, JM, 2009)
"Midodrine (10 mg) administered in the home environment effectively increases BP and reduces the incidence of hypotension; however these beneficial effects come at the expense of worsened BP instability and AD symptom intensity."5.69Clinical trial of home blood pressure monitoring following midodrine administration in hypotensive individuals with spinal cord injury. ( Bauman, WA; Dyson-Hudson, TA; Katzelnick, CG; Kirshblum, SC; Wecht, JM; Weir, JP, 2023)
"These findings suggest that midodrine 10mg may be efficacious for treatment of hypotension and orthostatic hypotension in select persons with tetraplegia."5.14Effects of midodrine hydrochloride on blood pressure and cerebral blood flow during orthostasis in persons with chronic tetraplegia. ( Bauman, WA; Handrakis, JP; Radulovic, M; Rosado-Rivera, D; Wecht, JM, 2010)
"We evaluated midodrine as oral treatment for pharmacologically induced priapism in spinal cord injured patients."3.75Oral midodrine for prostaglandin e1 induced priapism in spinal cord injured patients. ( Mieusset, R; Plante, P; Previnaire, JG; Soler, JM, 2009)
"To explore the effectiveness of various sources of self-stimulation, including oral midodrine, in triggering ejaculation in men with spinal cord injury (SCI), and to document the systematic variations in blood pressure at ejaculation and consider a revised definition of autonomic dysreflexia."3.74Blood pressure changes during sexual stimulation, ejaculation and midodrine treatment in men with spinal cord injury. ( Bélanger, M; Charvier, KF; Côté, M; Courtois, FJ; Leriche, A; Vézina, JG, 2008)
"However, treatment of hypotension is uncommon in the SCI population because there are few safe and effective pharmacological options available."2.94Double-blinded, placebo-controlled crossover trial to determine the effects of midodrine on blood pressure during cognitive testing in persons with SCI. ( Bauman, WA; Chiaravalloti, ND; Dyson-Hudson, TA; Katzelnick, CG; Kirshblum, SC; Weber, E; Wecht, JM; Weir, JP, 2020)
"Treatment with midodrine, 10 mg, was associated with elevated systolic blood pressure during peak exercise in 3 participants."2.71Double-blinded, placebo-controlled trial of midodrine for exercise performance enhancement in tetraplegia: a pilot study. ( Birk, CA; Birk, TJ; Hinderer, SR; Nieshoff, EC; Yavuzer, G, 2004)
"Treatment of orthostatic hypotension is an important consideration for many patients with spinal cord injuries, especially those with an injury to the cervical cord."2.40Orthostatic hypotension in spinal cord injured patients. ( Blackmer, J, 1997)
"Oral midodrine may further increase ejaculation success, while maintaining autonomy."1.35Perceived physiological and orgasmic sensations at ejaculation in spinal cord injured men. ( Bélanger, M; Charvier, K; Côté, I; Courtois, F; Fournier, C; Jacquemin, G; Leriche, A; Raymond, D; Vézina, JG, 2008)
"Midodrine is a safe and efficient adjunct to penile vibratory stimulation for anejaculation in spinal cord injured patients."1.34Midodrine improves ejaculation in spinal cord injured men. ( Chartier-Kastler, E; Denys, P; Plante, P; Previnaire, JG; Soler, JM, 2007)
"Midodrine was prescribed, and other medications with possible adverse effects were adjusted."1.31Midodrine for the management of orthostatic hypotension in patients with spinal cord injury: A case report. ( Barrs, K; Karlin, L; Lublin, P; Mukand, J, 2001)
"This led to successfully oral treatment of the orthostatic hypotension with clonidine 150 micrograms bd and midodrine 10 mg bd."1.28Pharmacological evidence of alpha 1- and alpha 2-adrenergic supersensitivity in orthostatic hypotension due to spinal cord injury: a case report. ( Arias, A; Berlan, M; Montastruc, JL; Rascol, A; Senard, JM; Tran, MA, 1991)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (9.52)18.2507
2000's9 (42.86)29.6817
2010's8 (38.10)24.3611
2020's2 (9.52)2.80

Authors

AuthorsStudies
Wecht, JM4
Weir, JP3
Katzelnick, CG2
Dyson-Hudson, TA2
Bauman, WA4
Kirshblum, SC2
Chiaravalloti, ND1
Weber, E1
Hadiji, N1
Benbouzid, R1
Previnaire, JG5
Leblond, C1
Mieusset, R2
Enjalbert, M1
Soler, JM5
Phillips, AA3
Krassioukov, AV3
Ainslie, PN3
Warburton, DE4
Cote, AT1
Leduc, BE1
Fournier, C2
Jacquemin, G2
Lepage, Y1
Vinet, B1
Hétu, PO1
Chagnon, M1
Radulovic, M2
Krassioukov, A1
Eng, JJ1
Teasell, R1
Plante, P3
Rosado-Rivera, D1
Handrakis, JP1
Nieshoff, EC1
Birk, TJ1
Birk, CA1
Hinderer, SR1
Yavuzer, G1
Denys, P2
Chartier-Kastler, E2
Courtois, FJ1
Charvier, KF1
Leriche, A2
Vézina, JG2
Côté, M1
Bélanger, M2
Courtois, F1
Charvier, K1
Côté, I1
Raymond, D1
Blackmer, J1
Mukand, J1
Karlin, L1
Barrs, K1
Lublin, P1
Staerman, F1
Bryckaert, PE1
Youinou, Y1
Colin, J1
Brandt, B1
Lardennois, B1
Senard, JM1
Arias, A1
Berlan, M1
Tran, MA1
Rascol, A1
Montastruc, JL1

Clinical Trials (8)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Blood Pressure, Cerebral Blood Flow and Cognition in SCI[NCT02307565]Phase 360 participants (Actual)Interventional2014-03-31Completed
Restoring Hemodynamic Stability Using Targeted Epidural Spinal Stimulation Following Spinal Cord Injury[NCT04994886]8 participants (Anticipated)Interventional2021-06-08Recruiting
Dose Response to the Norepinephrine Precursor Droxidopa in Hypotensive Individuals With Spinal Cord Injury[NCT03602014]Phase 422 participants (Actual)Interventional2018-06-01Completed
Restoring Hemodynamic Stability Using Targeted Epidural Spinal Stimulation Following Spinal Cord Injury[NCT05044923]8 participants (Anticipated)Interventional2021-12-31Recruiting
Epidural Electrical Stimulation to Restore Hemodynamic Stability and Trunk Control in People With Spinal Cord Injury[NCT05111093]20 participants (Anticipated)Interventional2021-11-29Recruiting
The Effects of Spinal Cord Stimulation on Autonomic Function in People With Spinal Cord Injury[NCT03924388]46 participants (Anticipated)Interventional2020-02-01Not yet recruiting
Study on Preliminary Safety and Efficacy of the ARC Therapy Using the ARC-IM Lumbar System to Support Mobility in People With Chronic Spinal Cord Injury[NCT05942339]8 participants (Anticipated)Interventional2023-08-31Not yet recruiting
A Dose Response Trial Using 5 and 10 mg. of Midodrine Hydrochloride to Treat Orthostatic Hypotension in Persons With SCI[NCT00426842]Phase 211 participants (Actual)Interventional2007-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Systolic Blood Pressure

brachial artery systolic blood pressure (mmHg) (NCT00426842)
Timeframe: The difference between the average supine systolic blood pressure and the average systolic blood pressure at 45 degree head-up tilt position.

,,
InterventionmmHg (Mean)
Baseline Blood PressureHead-up Tilt Blood Pressure
Midodrine 10 mg102109
Midodrine 5 mg9796
No-drug9887

Reviews

2 reviews available for midodrine and Injuries, Spinal Cord

ArticleYear
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
A systematic review of the management of orthostatic hypotension after spinal cord injury.
    Archives of physical medicine and rehabilitation, 2009, Volume: 90, Issue:5

    Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypotension, Orthostatic; Injury Sever

2009
Orthostatic hypotension in spinal cord injured patients.
    The journal of spinal cord medicine, 1997, Volume: 20, Issue:2

    Topics: Adolescent; Brain Stem; Combined Modality Therapy; Efferent Pathways; Humans; Hypotension, Orthostat

1997

Trials

8 trials available for midodrine and Injuries, Spinal Cord

ArticleYear
Clinical trial of home blood pressure monitoring following midodrine administration in hypotensive individuals with spinal cord injury.
    The journal of spinal cord medicine, 2023, Volume: 46, Issue:4

    Topics: Autonomic Dysreflexia; Blood Pressure Monitoring, Ambulatory; Humans; Hypotension; Hypotension, Orth

2023
Double-blinded, placebo-controlled crossover trial to determine the effects of midodrine on blood pressure during cognitive testing in persons with SCI.
    Spinal cord, 2020, Volume: 58, Issue:9

    Topics: Adult; Blood Pressure; Cerebrovascular Circulation; Chronic Disease; Cognition; Cross-Over Studies;

2020
Perturbed and spontaneous regional cerebral blood flow responses to changes in blood pressure after high-level spinal cord injury: the effect of midodrine.
    Journal of applied physiology (Bethesda, Md. : 1985), 2014, Mar-15, Volume: 116, Issue:6

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Pressure; British Columbia; Cerebrova

2014
Perturbed and spontaneous regional cerebral blood flow responses to changes in blood pressure after high-level spinal cord injury: the effect of midodrine.
    Journal of applied physiology (Bethesda, Md. : 1985), 2014, Mar-15, Volume: 116, Issue:6

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Pressure; British Columbia; Cerebrova

2014
Perturbed and spontaneous regional cerebral blood flow responses to changes in blood pressure after high-level spinal cord injury: the effect of midodrine.
    Journal of applied physiology (Bethesda, Md. : 1985), 2014, Mar-15, Volume: 116, Issue:6

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Pressure; British Columbia; Cerebrova

2014
Perturbed and spontaneous regional cerebral blood flow responses to changes in blood pressure after high-level spinal cord injury: the effect of midodrine.
    Journal of applied physiology (Bethesda, Md. : 1985), 2014, Mar-15, Volume: 116, Issue:6

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Pressure; British Columbia; Cerebrova

2014
Perturbed and spontaneous regional cerebral blood flow responses to changes in blood pressure after high-level spinal cord injury: the effect of midodrine.
    Journal of applied physiology (Bethesda, Md. : 1985), 2014, Mar-15, Volume: 116, Issue:6

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Pressure; British Columbia; Cerebrova

2014
Perturbed and spontaneous regional cerebral blood flow responses to changes in blood pressure after high-level spinal cord injury: the effect of midodrine.
    Journal of applied physiology (Bethesda, Md. : 1985), 2014, Mar-15, Volume: 116, Issue:6

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Pressure; British Columbia; Cerebrova

2014
Perturbed and spontaneous regional cerebral blood flow responses to changes in blood pressure after high-level spinal cord injury: the effect of midodrine.
    Journal of applied physiology (Bethesda, Md. : 1985), 2014, Mar-15, Volume: 116, Issue:6

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Pressure; British Columbia; Cerebrova

2014
Perturbed and spontaneous regional cerebral blood flow responses to changes in blood pressure after high-level spinal cord injury: the effect of midodrine.
    Journal of applied physiology (Bethesda, Md. : 1985), 2014, Mar-15, Volume: 116, Issue:6

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Pressure; British Columbia; Cerebrova

2014
Perturbed and spontaneous regional cerebral blood flow responses to changes in blood pressure after high-level spinal cord injury: the effect of midodrine.
    Journal of applied physiology (Bethesda, Md. : 1985), 2014, Mar-15, Volume: 116, Issue:6

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Pressure; British Columbia; Cerebrova

2014
Perturbed and spontaneous regional cerebral blood flow responses to changes in blood pressure after high-level spinal cord injury: the effect of midodrine.
    Journal of applied physiology (Bethesda, Md. : 1985), 2014, Mar-15, Volume: 116, Issue:6

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Pressure; British Columbia; Cerebrova

2014
Perturbed and spontaneous regional cerebral blood flow responses to changes in blood pressure after high-level spinal cord injury: the effect of midodrine.
    Journal of applied physiology (Bethesda, Md. : 1985), 2014, Mar-15, Volume: 116, Issue:6

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Pressure; British Columbia; Cerebrova

2014
Perturbed and spontaneous regional cerebral blood flow responses to changes in blood pressure after high-level spinal cord injury: the effect of midodrine.
    Journal of applied physiology (Bethesda, Md. : 1985), 2014, Mar-15, Volume: 116, Issue:6

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Pressure; British Columbia; Cerebrova

2014
Perturbed and spontaneous regional cerebral blood flow responses to changes in blood pressure after high-level spinal cord injury: the effect of midodrine.
    Journal of applied physiology (Bethesda, Md. : 1985), 2014, Mar-15, Volume: 116, Issue:6

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Pressure; British Columbia; Cerebrova

2014
Perturbed and spontaneous regional cerebral blood flow responses to changes in blood pressure after high-level spinal cord injury: the effect of midodrine.
    Journal of applied physiology (Bethesda, Md. : 1985), 2014, Mar-15, Volume: 116, Issue:6

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Pressure; British Columbia; Cerebrova

2014
Perturbed and spontaneous regional cerebral blood flow responses to changes in blood pressure after high-level spinal cord injury: the effect of midodrine.
    Journal of applied physiology (Bethesda, Md. : 1985), 2014, Mar-15, Volume: 116, Issue:6

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Pressure; British Columbia; Cerebrova

2014
Perturbed and spontaneous regional cerebral blood flow responses to changes in blood pressure after high-level spinal cord injury: the effect of midodrine.
    Journal of applied physiology (Bethesda, Md. : 1985), 2014, Mar-15, Volume: 116, Issue:6

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Pressure; British Columbia; Cerebrova

2014
Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: improved by alpha-1 agonist midodrine hydrochloride.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:5

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Flow Velocity; Cerebrovascular Circul

2014
Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: improved by alpha-1 agonist midodrine hydrochloride.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:5

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Flow Velocity; Cerebrovascular Circul

2014
Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: improved by alpha-1 agonist midodrine hydrochloride.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:5

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Flow Velocity; Cerebrovascular Circul

2014
Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: improved by alpha-1 agonist midodrine hydrochloride.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:5

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Flow Velocity; Cerebrovascular Circul

2014
Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: improved by alpha-1 agonist midodrine hydrochloride.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:5

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Flow Velocity; Cerebrovascular Circul

2014
Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: improved by alpha-1 agonist midodrine hydrochloride.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:5

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Flow Velocity; Cerebrovascular Circul

2014
Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: improved by alpha-1 agonist midodrine hydrochloride.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:5

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Flow Velocity; Cerebrovascular Circul

2014
Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: improved by alpha-1 agonist midodrine hydrochloride.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:5

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Flow Velocity; Cerebrovascular Circul

2014
Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: improved by alpha-1 agonist midodrine hydrochloride.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:5

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Flow Velocity; Cerebrovascular Circul

2014
Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: improved by alpha-1 agonist midodrine hydrochloride.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:5

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Flow Velocity; Cerebrovascular Circul

2014
Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: improved by alpha-1 agonist midodrine hydrochloride.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:5

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Flow Velocity; Cerebrovascular Circul

2014
Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: improved by alpha-1 agonist midodrine hydrochloride.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:5

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Flow Velocity; Cerebrovascular Circul

2014
Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: improved by alpha-1 agonist midodrine hydrochloride.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:5

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Flow Velocity; Cerebrovascular Circul

2014
Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: improved by alpha-1 agonist midodrine hydrochloride.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:5

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Flow Velocity; Cerebrovascular Circul

2014
Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: improved by alpha-1 agonist midodrine hydrochloride.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:5

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Flow Velocity; Cerebrovascular Circul

2014
Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: improved by alpha-1 agonist midodrine hydrochloride.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:5

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Flow Velocity; Cerebrovascular Circul

2014
Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: improved by alpha-1 agonist midodrine hydrochloride.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:5

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Flow Velocity; Cerebrovascular Circul

2014
Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: improved by alpha-1 agonist midodrine hydrochloride.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:5

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Flow Velocity; Cerebrovascular Circul

2014
Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: improved by alpha-1 agonist midodrine hydrochloride.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:5

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Flow Velocity; Cerebrovascular Circul

2014
Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: improved by alpha-1 agonist midodrine hydrochloride.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:5

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Flow Velocity; Cerebrovascular Circul

2014
Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: improved by alpha-1 agonist midodrine hydrochloride.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:5

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Flow Velocity; Cerebrovascular Circul

2014
Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: improved by alpha-1 agonist midodrine hydrochloride.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:5

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Flow Velocity; Cerebrovascular Circul

2014
Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: improved by alpha-1 agonist midodrine hydrochloride.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:5

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Flow Velocity; Cerebrovascular Circul

2014
Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: improved by alpha-1 agonist midodrine hydrochloride.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:5

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Flow Velocity; Cerebrovascular Circul

2014
Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: improved by alpha-1 agonist midodrine hydrochloride.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:5

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Blood Flow Velocity; Cerebrovascular Circul

2014
Midodrine in patients with spinal cord injury and anejaculation: A double-blind randomized placebo-controlled pilot study.
    The journal of spinal cord medicine, 2015, Volume: 38, Issue:1

    Topics: Adrenergic alpha-1 Receptor Agonists; Adult; Ejaculation; Genital Diseases, Male; Humans; Male; Midd

2015
Effects of midodrine and L-NAME on systemic and cerebral hemodynamics during cognitive activation in spinal cord injury and intact controls.
    Physiological reports, 2016, Volume: 4, Issue:3

    Topics: Adult; Blood Pressure; Cerebrovascular Circulation; Cognition; Female; Hemodynamics; Humans; Hypoten

2016
Effects of midodrine hydrochloride on blood pressure and cerebral blood flow during orthostasis in persons with chronic tetraplegia.
    Archives of physical medicine and rehabilitation, 2010, Volume: 91, Issue:9

    Topics: Adult; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Female; Humans; Hypotension; H

2010
Effects of midodrine hydrochloride on blood pressure and cerebral blood flow during orthostasis in persons with chronic tetraplegia.
    Archives of physical medicine and rehabilitation, 2010, Volume: 91, Issue:9

    Topics: Adult; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Female; Humans; Hypotension; H

2010
Effects of midodrine hydrochloride on blood pressure and cerebral blood flow during orthostasis in persons with chronic tetraplegia.
    Archives of physical medicine and rehabilitation, 2010, Volume: 91, Issue:9

    Topics: Adult; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Female; Humans; Hypotension; H

2010
Effects of midodrine hydrochloride on blood pressure and cerebral blood flow during orthostasis in persons with chronic tetraplegia.
    Archives of physical medicine and rehabilitation, 2010, Volume: 91, Issue:9

    Topics: Adult; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Female; Humans; Hypotension; H

2010
Effects of midodrine hydrochloride on blood pressure and cerebral blood flow during orthostasis in persons with chronic tetraplegia.
    Archives of physical medicine and rehabilitation, 2010, Volume: 91, Issue:9

    Topics: Adult; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Female; Humans; Hypotension; H

2010
Effects of midodrine hydrochloride on blood pressure and cerebral blood flow during orthostasis in persons with chronic tetraplegia.
    Archives of physical medicine and rehabilitation, 2010, Volume: 91, Issue:9

    Topics: Adult; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Female; Humans; Hypotension; H

2010
Effects of midodrine hydrochloride on blood pressure and cerebral blood flow during orthostasis in persons with chronic tetraplegia.
    Archives of physical medicine and rehabilitation, 2010, Volume: 91, Issue:9

    Topics: Adult; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Female; Humans; Hypotension; H

2010
Effects of midodrine hydrochloride on blood pressure and cerebral blood flow during orthostasis in persons with chronic tetraplegia.
    Archives of physical medicine and rehabilitation, 2010, Volume: 91, Issue:9

    Topics: Adult; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Female; Humans; Hypotension; H

2010
Effects of midodrine hydrochloride on blood pressure and cerebral blood flow during orthostasis in persons with chronic tetraplegia.
    Archives of physical medicine and rehabilitation, 2010, Volume: 91, Issue:9

    Topics: Adult; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Female; Humans; Hypotension; H

2010
Double-blinded, placebo-controlled trial of midodrine for exercise performance enhancement in tetraplegia: a pilot study.
    The journal of spinal cord medicine, 2004, Volume: 27, Issue:3

    Topics: Adrenergic alpha-Agonists; Adult; Blood Pressure; Cross-Over Studies; Dose-Response Relationship, Dr

2004

Other Studies

11 other studies available for midodrine and Injuries, Spinal Cord

ArticleYear
[Evaluation of the management of erectile and ejaculatory dysfunction in a series of 90 patients with spinal cord injuries].
    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 2013, Volume: 23, Issue:17

    Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Aged; Alprostadil; Ejaculation; Erectile Dysfunction;

2013
Increased central arterial stiffness explains baroreflex dysfunction in spinal cord injury.
    Journal of neurotrauma, 2014, Jun-15, Volume: 31, Issue:12

    Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Adult; Baroreflex; Blood Pressure; Carotid Artery,

2014
Oral midodrine for prostaglandin e1 induced priapism in spinal cord injured patients.
    The Journal of urology, 2009, Volume: 182, Issue:3

    Topics: Administration, Oral; Adrenergic alpha-Agonists; Adult; Alprostadil; Erectile Dysfunction; Humans; I

2009
Ejaculatory dysfunction in spinal cord injury men is suggestive of dyssynergic ejaculation.
    European journal of physical and rehabilitation medicine, 2011, Volume: 47, Issue:4

    Topics: Ejaculation; Humans; Male; Midodrine; Sexual Dysfunction, Physiological; Spinal Cord Injuries; Vasoc

2011
Midodrine improves ejaculation in spinal cord injured men.
    The Journal of urology, 2007, Volume: 178, Issue:5

    Topics: Administration, Oral; Adrenergic alpha-Agonists; Adult; Coitus; Dose-Response Relationship, Drug; Ej

2007
Blood pressure changes during sexual stimulation, ejaculation and midodrine treatment in men with spinal cord injury.
    BJU international, 2008, Volume: 101, Issue:3

    Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Aged; Autonomic Dysreflexia; Blood Pressure; Ejaculati

2008
Midodrine improves orgasm in spinal cord-injured men: the effects of autonomic stimulation.
    The journal of sexual medicine, 2008, Volume: 5, Issue:12

    Topics: Adrenergic alpha-Agonists; Adult; Autonomic Nervous System; Blood Pressure; Dose-Response Relationsh

2008
Perceived physiological and orgasmic sensations at ejaculation in spinal cord injured men.
    The journal of sexual medicine, 2008, Volume: 5, Issue:10

    Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Autonomic Dysreflexia; Autonomic Nervous System Diseas

2008
Midodrine for the management of orthostatic hypotension in patients with spinal cord injury: A case report.
    Archives of physical medicine and rehabilitation, 2001, Volume: 82, Issue:5

    Topics: Adult; Blood Pressure; Humans; Hypotension, Orthostatic; Male; Midodrine; Recovery of Function; Spin

2001
[Pharmacologic stimulation of ejaculation with midodrine hydrochloride (Gutron) for medically assisted reproduction in spinal injury].
    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 2001, Volume: 11, Issue:6

    Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Ejaculation; Humans; Midodrine; Reproductive Technique

2001
Pharmacological evidence of alpha 1- and alpha 2-adrenergic supersensitivity in orthostatic hypotension due to spinal cord injury: a case report.
    European journal of clinical pharmacology, 1991, Volume: 41, Issue:6

    Topics: Blood Pressure; Chronic Disease; Clonidine; Efferent Pathways; Humans; Hypotension, Orthostatic; Mal

1991