Page last updated: 2024-10-31

midodrine and Heart Failure

midodrine has been researched along with Heart Failure in 9 studies

Midodrine: An ethanolamine derivative that is an adrenergic alpha-1 agonist. It is used as a vasoconstrictor agent in the treatment of HYPOTENSION.
midodrine : An aromatic ether that is 1,4-dimethoxybenzene which is substituted at position 2 by a 2-(glycylamino)-1-hydroxyethyl group. A direct-acting sympathomimetic with selective alpha-adrenergic agonist activity, it is used (generally as its hydrochloride salt) as a peripheral vasoconstrictor in the treatment of certain hypotensive states. The main active moiety is its major metabolite, deglymidodrine.

Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"Outpatient dialysis is possible and relieves the symptoms of congestive heart failure in patients with poor heart function, low blood pressure, and advanced age when midodrine is given immediately before and during the procedure."7.75Hemodialysis in hypotensive heart failure using midodrine. ( Bergman, SM, 2009)
"Midodrine was started as a last resort attempt to wean off vasopressors."5.91Midodrine in end-stage heart failure. ( Franqui-Rivera, H; Gonzalez-Cordero, A; Mesa-Pabón, M; Nieves-Rivera, J; Ortiz-Troche, S, 2023)
"We compared incidence rates of hospitalizations for all causes, and for congestive heart failure between users of fludrocortisone and users of midodrine in a retrospective cohort study of Tennessee Medicaid adult enrollees (1995-2009)."3.85Fludrocortisone Is Associated With a Higher Risk of All-Cause Hospitalizations Compared With Midodrine in Patients With Orthostatic Hypotension. ( Biaggioni, I; Griffin, MR; Grijalva, CG; Shibao, CA, 2017)
"Outpatient dialysis is possible and relieves the symptoms of congestive heart failure in patients with poor heart function, low blood pressure, and advanced age when midodrine is given immediately before and during the procedure."3.75Hemodialysis in hypotensive heart failure using midodrine. ( Bergman, SM, 2009)
"Orthostatic hypotension is more frequent in polymedicated elderly patients with co-morbidities (prevalence 23%)."2.48[Orthostatic hypotension: implications for the treatment of cardiovascular diseases]. ( Mansourati, J, 2012)
"Midodrine was started as a last resort attempt to wean off vasopressors."1.91Midodrine in end-stage heart failure. ( Franqui-Rivera, H; Gonzalez-Cordero, A; Mesa-Pabón, M; Nieves-Rivera, J; Ortiz-Troche, S, 2023)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's3 (33.33)24.3611
2020's4 (44.44)2.80

Authors

AuthorsStudies
Fernández-Fernández, FJ1
Ameneiros-Lago, E1
Sardina-Ferreiro, R1
Sinagra, G1
Fabris, E1
Marigliano, B1
Internullo, M1
Scuro, L1
Tavanti, A1
Del Vecchio, LR1
Schito, MB1
Colombo, GM1
Guglielmelli, E1
Reed, BN1
Gale, SE1
Ramani, G1
Gonzalez-Cordero, A1
Ortiz-Troche, S1
Nieves-Rivera, J1
Mesa-Pabón, M1
Franqui-Rivera, H1
Grijalva, CG1
Biaggioni, I1
Griffin, MR1
Shibao, CA1
Bergman, SM1
Mansourati, J1
Montagnac, R1
Clavel, P1
Delhotal-Landes, B1
Flouvat, B1
Poulain, S1
Schillinger, F1

Reviews

1 review available for midodrine and Heart Failure

ArticleYear
[Orthostatic hypotension: implications for the treatment of cardiovascular diseases].
    Presse medicale (Paris, France : 1983), 2012, Volume: 41, Issue:11

    Topics: Age Factors; Aged; Antihypertensive Agents; Cardiovascular Agents; Cardiovascular Diseases; Contrain

2012

Other Studies

8 other studies available for midodrine and Heart Failure

ArticleYear
Might midodrine be useful in patients with decompensated and worsening chronic heart failure?
    European journal of internal medicine, 2022, Volume: 105

    Topics: Blood Pressure; Heart Failure; Humans; Midodrine

2022
Might midodrine be useful in patients with decompensated and worsening chronic heart failure? Author's reply.
    European journal of internal medicine, 2022, Volume: 105

    Topics: Blood Pressure; Chronic Disease; Heart Failure; Humans; Midodrine

2022
Midodrine and albumin as a possible "winning pair" in managing paracentesis-induced circulatory dysfunction: a clinical case report.
    European review for medical and pharmacological sciences, 2022, Volume: 26, Issue:24

    Topics: Albumins; Ascites; Diuretics; Female; Heart Failure; Humans; Liver Cirrhosis; Middle Aged; Midodrine

2022
Continuation of Newly Initiated Midodrine Therapy: Appropriate in Patients With Heart Failure?
    Critical care medicine, 2019, Volume: 47, Issue:10

    Topics: Critical Care; Heart Failure; Humans; Midodrine; Patient Discharge; Retrospective Studies

2019
Midodrine in end-stage heart failure.
    BMJ supportive & palliative care, 2023, Volume: 13, Issue:e1

    Topics: Heart Failure; Hospitalization; Humans; Hypotension; Male; Midodrine; Vasoconstrictor Agents

2023
Fludrocortisone Is Associated With a Higher Risk of All-Cause Hospitalizations Compared With Midodrine in Patients With Orthostatic Hypotension.
    Journal of the American Heart Association, 2017, Oct-12, Volume: 6, Issue:10

    Topics: Adrenergic alpha-1 Receptor Agonists; Aged; Blood Pressure; Databases, Factual; Female; Fludrocortis

2017
Hemodialysis in hypotensive heart failure using midodrine.
    The American journal of the medical sciences, 2009, Volume: 338, Issue:6

    Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Blood Pressure; Female; Heart Failure; Humans; H

2009
[Midodrine (Gutron) treatment of permanent arterial hypotension in a chronic hemodialysis patient].
    Nephrologie, 2000, Volume: 21, Issue:4

    Topics: Adrenergic alpha-Agonists; Chronic Disease; Heart Failure; Humans; Hypertrophy, Left Ventricular; Hy

2000