Page last updated: 2024-10-31

midodrine and Circulatory Collapse

midodrine has been researched along with Circulatory Collapse in 6 studies

Midodrine: An ethanolamine derivative that is an adrenergic alpha-1 agonist. It is used as a vasoconstrictor agent in the treatment of HYPOTENSION.
midodrine : An aromatic ether that is 1,4-dimethoxybenzene which is substituted at position 2 by a 2-(glycylamino)-1-hydroxyethyl group. A direct-acting sympathomimetic with selective alpha-adrenergic agonist activity, it is used (generally as its hydrochloride salt) as a peripheral vasoconstrictor in the treatment of certain hypotensive states. The main active moiety is its major metabolite, deglymidodrine.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the effects of midodrine in addition to intravenous vasopressor therapy on outcomes in adults recovering from shock."9.05Midodrine as an Adjuvant to Intravenous Vasopressor Agents in Adults With Resolving Shock: Systematic Review and Meta-Analysis. ( Balk, RA; Hammond, DA; Menich, BE; Peksa, GD; Smith, MN; Trivedi, AP, 2020)
"Midodrine has been used as an oral agent for haemodynamic support in patients with orthostatic hypotension or cirrhosis."5.72Midodrine therapy for vasopressor dependent shock in the intensive care unit: a protocol for a systematic review and meta-analysis. ( Bagshaw, SM; Fiest, K; Kamaleldin, M; Karvellas, CJ; Kilcommons, S; Kutsogiannis, J; Lau, V; MacIntyre, E; Opgenorth, D; Rewa, OG; Rochwerg, B; Senaratne, J; Slemko, J; Sligl, W; Wang, X, 2022)
"To evaluate the effects of midodrine in addition to intravenous vasopressor therapy on outcomes in adults recovering from shock."5.05Midodrine as an Adjuvant to Intravenous Vasopressor Agents in Adults With Resolving Shock: Systematic Review and Meta-Analysis. ( Balk, RA; Hammond, DA; Menich, BE; Peksa, GD; Smith, MN; Trivedi, AP, 2020)
"Treatment with midodrine and albumin was associated with a slight but significant decrease in plasma renin activity and aldosterone compared to placebo (renin -4."2.87Midodrine and albumin for prevention of complications in patients with cirrhosis awaiting liver transplantation. A randomized placebo-controlled trial. ( Ariza, X; Castellote, J; Colmenero, J; Córdoba, J; de Prada, G; Fabrellas, N; Garcia-Martínez, R; Ginès, P; Graupera, I; Guevara, M; Huelin, P; Lopez Benaiges, E; Manríquez, M; Márquez, F; Martín-Llahí, M; Moreira, R; Navasa, M; Nazar, A; Pavesi, M; Pose, E; Simón-Talero, M; Solà, E; Solé, C; Suñé, P; Torrens, M; Vargas, V; Ventura, M; Xiol, X, 2018)
"Midodrine has been used as an oral agent for haemodynamic support in patients with orthostatic hypotension or cirrhosis."1.72Midodrine therapy for vasopressor dependent shock in the intensive care unit: a protocol for a systematic review and meta-analysis. ( Bagshaw, SM; Fiest, K; Kamaleldin, M; Karvellas, CJ; Kilcommons, S; Kutsogiannis, J; Lau, V; MacIntyre, E; Opgenorth, D; Rewa, OG; Rochwerg, B; Senaratne, J; Slemko, J; Sligl, W; Wang, X, 2022)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's5 (83.33)2.80

Authors

AuthorsStudies
Kamaleldin, M3
Kilcommons, S3
Opgenorth, D3
Fiest, K3
Karvellas, CJ3
Kutsogiannis, J3
Lau, V3
MacIntyre, E3
Rochwerg, B3
Senaratne, J3
Slemko, J3
Sligl, W3
Wang, X3
Bagshaw, SM3
Rewa, OG3
Marigliano, B1
Internullo, M1
Scuro, L1
Tavanti, A1
Del Vecchio, LR1
Schito, MB1
Colombo, GM1
Guglielmelli, E1
Khokher, W1
Iftikhar, S1
Beran, A1
Burmeister, C1
Abrahamian, A1
Abuhelwa, Z1
Malhas, SE1
Khuder, S1
Assaly, R1
Tripathy, A1
Maiti, R1
Jena, M1
Mishra, A1
Srinivasan, A1
Solà, E1
Solé, C1
Simón-Talero, M1
Martín-Llahí, M1
Castellote, J1
Garcia-Martínez, R1
Moreira, R1
Torrens, M1
Márquez, F1
Fabrellas, N1
de Prada, G1
Huelin, P1
Lopez Benaiges, E1
Ventura, M1
Manríquez, M1
Nazar, A1
Ariza, X1
Suñé, P1
Graupera, I1
Pose, E1
Colmenero, J1
Pavesi, M1
Guevara, M1
Navasa, M1
Xiol, X1
Córdoba, J1
Vargas, V1
Ginès, P1
Hammond, DA1
Smith, MN1
Peksa, GD1
Trivedi, AP1
Balk, RA1
Menich, BE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Midodrine and Albumin for Cirrhotic Patients in the Waiting List for Liver Transplantation[NCT00839358]Phase 4199 participants (Actual)Interventional2008-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for midodrine and Circulatory Collapse

ArticleYear
Utility of Midodrine During the Recovery Phase of Shock: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
    American journal of therapeutics, 2023, 05-01, Volume: 30, Issue:3

    Topics: Humans; Midodrine; Randomized Controlled Trials as Topic; Shock; Vasoconstrictor Agents

2023
Effect of alpha agonists on the prevention of postparacentesis circulatory dysfunction in patients with refractory or recurrent ascites: a meta-analysis.
    European journal of gastroenterology & hepatology, 2020, Volume: 32, Issue:3

    Topics: Aldosterone; Ascites; Humans; Midodrine; Shock

2020
Midodrine as an Adjuvant to Intravenous Vasopressor Agents in Adults With Resolving Shock: Systematic Review and Meta-Analysis.
    Journal of intensive care medicine, 2020, Volume: 35, Issue:11

    Topics: Administration, Intravenous; Adult; Humans; Intensive Care Units; Midodrine; Shock; Vasoconstrictor

2020

Trials

1 trial available for midodrine and Circulatory Collapse

ArticleYear
Midodrine and albumin for prevention of complications in patients with cirrhosis awaiting liver transplantation. A randomized placebo-controlled trial.
    Journal of hepatology, 2018, Volume: 69, Issue:6

    Topics: Adult; Aged; Albumins; Aldosterone; Ascites; Double-Blind Method; Female; Follow-Up Studies; Humans;

2018

Other Studies

2 other studies available for midodrine and Circulatory Collapse

ArticleYear
Midodrine therapy for vasopressor dependent shock in the intensive care unit: a protocol for a systematic review and meta-analysis.
    BMJ open, 2022, 11-23, Volume: 12, Issue:11

    Topics: Critical Illness; Humans; Intensive Care Units; Meta-Analysis as Topic; Midodrine; Review Literature

2022
Midodrine therapy for vasopressor dependent shock in the intensive care unit: a protocol for a systematic review and meta-analysis.
    BMJ open, 2022, 11-23, Volume: 12, Issue:11

    Topics: Critical Illness; Humans; Intensive Care Units; Meta-Analysis as Topic; Midodrine; Review Literature

2022
Midodrine therapy for vasopressor dependent shock in the intensive care unit: a protocol for a systematic review and meta-analysis.
    BMJ open, 2022, 11-23, Volume: 12, Issue:11

    Topics: Critical Illness; Humans; Intensive Care Units; Meta-Analysis as Topic; Midodrine; Review Literature

2022
Midodrine therapy for vasopressor dependent shock in the intensive care unit: a protocol for a systematic review and meta-analysis.
    BMJ open, 2022, 11-23, Volume: 12, Issue:11

    Topics: Critical Illness; Humans; Intensive Care Units; Meta-Analysis as Topic; Midodrine; Review Literature

2022
Midodrine therapy for vasopressor dependent shock in the intensive care unit: a protocol for a systematic review and meta-analysis.
    BMJ open, 2022, 11-23, Volume: 12, Issue:11

    Topics: Critical Illness; Humans; Intensive Care Units; Meta-Analysis as Topic; Midodrine; Review Literature

2022
Midodrine therapy for vasopressor dependent shock in the intensive care unit: a protocol for a systematic review and meta-analysis.
    BMJ open, 2022, 11-23, Volume: 12, Issue:11

    Topics: Critical Illness; Humans; Intensive Care Units; Meta-Analysis as Topic; Midodrine; Review Literature

2022
Midodrine therapy for vasopressor dependent shock in the intensive care unit: a protocol for a systematic review and meta-analysis.
    BMJ open, 2022, 11-23, Volume: 12, Issue:11

    Topics: Critical Illness; Humans; Intensive Care Units; Meta-Analysis as Topic; Midodrine; Review Literature

2022
Midodrine therapy for vasopressor dependent shock in the intensive care unit: a protocol for a systematic review and meta-analysis.
    BMJ open, 2022, 11-23, Volume: 12, Issue:11

    Topics: Critical Illness; Humans; Intensive Care Units; Meta-Analysis as Topic; Midodrine; Review Literature

2022
Midodrine therapy for vasopressor dependent shock in the intensive care unit: a protocol for a systematic review and meta-analysis.
    BMJ open, 2022, 11-23, Volume: 12, Issue:11

    Topics: Critical Illness; Humans; Intensive Care Units; Meta-Analysis as Topic; Midodrine; Review Literature

2022
Midodrine and albumin as a possible "winning pair" in managing paracentesis-induced circulatory dysfunction: a clinical case report.
    European review for medical and pharmacological sciences, 2022, Volume: 26, Issue:24

    Topics: Albumins; Ascites; Diuretics; Female; Heart Failure; Humans; Liver Cirrhosis; Middle Aged; Midodrine

2022