midodrine has been researched along with Bradyarrhythmia in 4 studies
Midodrine: An ethanolamine derivative that is an adrenergic alpha-1 agonist. It is used as a vasoconstrictor agent in the treatment of HYPOTENSION.
midodrine : An aromatic ether that is 1,4-dimethoxybenzene which is substituted at position 2 by a 2-(glycylamino)-1-hydroxyethyl group. A direct-acting sympathomimetic with selective alpha-adrenergic agonist activity, it is used (generally as its hydrochloride salt) as a peripheral vasoconstrictor in the treatment of certain hypotensive states. The main active moiety is its major metabolite, deglymidodrine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe a man in his 40s with a history of chronic intranasal cocaine use and C5-C7 incomplete quadriplegia complicated by neurogenic orthostatic hypotension, admitted to the intensive care unit for worsening bradycardia and hypotension requiring initiation of dopamine and an increase of his home midodrine dose." | 8.31 | Refractory bradycardia and hypotension in patients with autonomic dysfunction treated with pseudoephedrine. ( Curran, C; Davoudi, F; Foster, G; Gordan, P, 2023) |
| " Although a beta blocker was not effective in preventing tilt-induced hypotension and bradycardia, midodrine hydrochloride (alpha-1 stimulant) or atropine prevented it." | 7.68 | A case of vasovagal syncope with convulsions--the effects of midodrine hydrochloride. ( Aizawa, Y; Igarashi, Y; Izumi, T; Koyama, S; Matsubara, T; Ohshima, M; Tamura, Y; Yamaguchi, T; Yamazaki, Y; Yamazoe, M, 1992) |
| "We describe a man in his 40s with a history of chronic intranasal cocaine use and C5-C7 incomplete quadriplegia complicated by neurogenic orthostatic hypotension, admitted to the intensive care unit for worsening bradycardia and hypotension requiring initiation of dopamine and an increase of his home midodrine dose." | 4.31 | Refractory bradycardia and hypotension in patients with autonomic dysfunction treated with pseudoephedrine. ( Curran, C; Davoudi, F; Foster, G; Gordan, P, 2023) |
| " Although a beta blocker was not effective in preventing tilt-induced hypotension and bradycardia, midodrine hydrochloride (alpha-1 stimulant) or atropine prevented it." | 3.68 | A case of vasovagal syncope with convulsions--the effects of midodrine hydrochloride. ( Aizawa, Y; Igarashi, Y; Izumi, T; Koyama, S; Matsubara, T; Ohshima, M; Tamura, Y; Yamaguchi, T; Yamazaki, Y; Yamazoe, M, 1992) |
| "If cardiac syncope is unlikely, reflex (neurally mediated) syncope and orthostatic hypotension are the most frequent causes of transient loss of consciousness." | 2.72 | New insights in diagnostics and therapies in syncope: a novel approach to non-cardiac syncope. ( Brignole, M; Rivasi, G, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Curran, C | 1 |
| Davoudi, F | 1 |
| Foster, G | 1 |
| Gordan, P | 1 |
| Brignole, M | 1 |
| Rivasi, G | 1 |
| Wong, LY | 1 |
| Wong, A | 1 |
| Robertson, T | 1 |
| Burns, K | 1 |
| Roberts, M | 1 |
| Isbister, GK | 1 |
| Koyama, S | 1 |
| Matsubara, T | 1 |
| Aizawa, Y | 1 |
| Ohshima, M | 1 |
| Yamaguchi, T | 1 |
| Yamazaki, Y | 1 |
| Igarashi, Y | 1 |
| Tamura, Y | 1 |
| Yamazoe, M | 1 |
| Izumi, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Assessment of the Mechanism of Non-cardiac Syncope by 24-hour Ambulatory Blood Pressure Monitoring (ABPM) and Tilt-table Short Cardiovascular Autonomic Function Battery (SCAFB)[NCT05728255] | 275 participants (Anticipated) | Observational | 2023-04-30 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for midodrine and Bradyarrhythmia
| Article | Year |
|---|---|
New insights in diagnostics and therapies in syncope: a novel approach to non-cardiac syncope.
Topics: Accidental Falls; Adenosine; Antihypertensive Agents; Atomoxetine Hydrochloride; Atrioventricular No | 2021 |
3 other studies available for midodrine and Bradyarrhythmia
| Article | Year |
|---|---|
Refractory bradycardia and hypotension in patients with autonomic dysfunction treated with pseudoephedrine.
Topics: Autonomic Nervous System Diseases; Bradycardia; Dopamine; Humans; Hypotension; Hypotension, Orthosta | 2023 |
Severe Hypertension and Bradycardia Secondary to Midodrine Overdose.
Topics: Adrenergic alpha-1 Receptor Antagonists; Blood Pressure; Bradycardia; Drug Overdose; Female; Glasgow | 2017 |
A case of vasovagal syncope with convulsions--the effects of midodrine hydrochloride.
Topics: Adult; Blood Pressure; Bradycardia; Female; Humans; Hypotension; Midodrine; Seizures; Syncope; Vagus | 1992 |