midodrine has been researched along with Aging in 4 studies
Midodrine: An ethanolamine derivative that is an adrenergic alpha-1 agonist. It is used as a vasoconstrictor agent in the treatment of HYPOTENSION.
midodrine : An aromatic ether that is 1,4-dimethoxybenzene which is substituted at position 2 by a 2-(glycylamino)-1-hydroxyethyl group. A direct-acting sympathomimetic with selective alpha-adrenergic agonist activity, it is used (generally as its hydrochloride salt) as a peripheral vasoconstrictor in the treatment of certain hypotensive states. The main active moiety is its major metabolite, deglymidodrine.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Orthostatic hypotension is a common problem among elderly patients, associated with significant morbidity and mortality." | 2.44 | Orthostatic hypotension in the elderly: diagnosis and treatment. ( Gupta, V; Lipsitz, LA, 2007) |
| "Parkinson's disease is a cause of primary autonomic failure with involvement of the peripheral nervous system." | 2.42 | [Blood pressure disorders during idiopathic Parkinson's disease]. ( Senard, JM, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Joseph, A | 1 |
| Wanono, R | 1 |
| Flamant, M | 1 |
| Vidal-Petiot, E | 1 |
| Senard, JM | 1 |
| Gupta, V | 1 |
| Lipsitz, LA | 1 |
| Takahashi, S | 1 |
| Moriyama, N | 1 |
| Yamazaki, R | 1 |
| Kawabe, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Insulin on Hypotension and Sarcopenia[NCT03248271] | 0 participants (Actual) | Observational | 2017-10-01 | Withdrawn (stopped due to Study design was changed to the study was changed to Insulin, hypotension and sarcopenia.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for midodrine and Aging
| Article | Year |
|---|---|
Orthostatic hypotension: A review.
Topics: Aging; Anti-Inflammatory Agents; Drug Therapy, Combination; Fludrocortisone; Humans; Hypotension, Or | 2017 |
[Blood pressure disorders during idiopathic Parkinson's disease].
Topics: Adrenergic alpha-Agonists; Aged; Aging; Fludrocortisone; Humans; Hypotension, Orthostatic; Midodrine | 2003 |
Orthostatic hypotension in the elderly: diagnosis and treatment.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Aging; Anti-Inflammatory Agents; Blood Pressure | 2007 |
1 other study available for midodrine and Aging
| Article | Year |
|---|---|
Urodynamic analysis of age-related changes of alpha 1-adrenoceptor responsiveness in female beagle dogs.
Topics: Adrenergic alpha-Agonists; Aging; Animals; Dogs; Female; Midodrine; Receptors, Adrenergic, alpha; Ur | 1996 |