Page last updated: 2024-10-31

midodrine and Acute Kidney Injury

midodrine has been researched along with Acute Kidney Injury in 6 studies

Midodrine: An ethanolamine derivative that is an adrenergic alpha-1 agonist. It is used as a vasoconstrictor agent in the treatment of HYPOTENSION.
midodrine : An aromatic ether that is 1,4-dimethoxybenzene which is substituted at position 2 by a 2-(glycylamino)-1-hydroxyethyl group. A direct-acting sympathomimetic with selective alpha-adrenergic agonist activity, it is used (generally as its hydrochloride salt) as a peripheral vasoconstrictor in the treatment of certain hypotensive states. The main active moiety is its major metabolite, deglymidodrine.

Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.

Research Excerpts

ExcerptRelevanceReference
"Midodrine along with albumin infusion, is helpful in the secondary prophylaxis of HRS-AKI and reduces the number of ascites tap."8.02Midodrine and albumin versus albumin alone for the secondary prophylaxis of acute kidney injury in a patient with cirrhosis and ascites. ( Arora, A; Bansal, N; Kumar, A; Puri, P; Sharma, P; ShriHari, AA; Singla, V, 2021)
"Midodrine along with albumin infusion, is helpful in the secondary prophylaxis of HRS-AKI and reduces the number of ascites tap."4.02Midodrine and albumin versus albumin alone for the secondary prophylaxis of acute kidney injury in a patient with cirrhosis and ascites. ( Arora, A; Bansal, N; Kumar, A; Puri, P; Sharma, P; ShriHari, AA; Singla, V, 2021)
"The hepatorenal syndrome is a well-recognized complication of advanced cirrhosis and is usually associated with an accelerated course to death unless liver transplantation is performed."2.53Emerging hepatic syndromes: pathophysiology, diagnosis and treatment. ( Bertino, G; Crisafulli, E; Demma, S; Koukias, N; Privitera, G; Purrello, F; Spadaro, L; Tsochatzis, EA, 2016)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's3 (50.00)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Flamm, SL1
Wong, F1
Ahn, J1
Kamath, PS1
Sharma, P1
Puri, P1
Bansal, N1
Singla, V1
Kumar, A1
ShriHari, AA1
Arora, A1
Velez, JC1
Kadian, M1
Taburyanskaya, M1
Bohm, NM1
Delay, TA1
Karakala, N1
Rockey, DC1
Nietert, PJ1
Goodwin, AJ1
Whelan, TP1
Bertino, G1
Privitera, G1
Purrello, F1
Demma, S1
Crisafulli, E1
Spadaro, L1
Koukias, N1
Tsochatzis, EA1
Dong, T1
Aronsohn, A1
Gautham Reddy, K1
Te, HS1
Esrailian, E1
Runyon, BA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Rifaximin Prophylaxis Against Recurrence of Spontaneous Bacterial Peritonitis and Occurrence of Hepatorenal Syndrome in Decompensated Cirrhotic Egyptian Patients[NCT05621005]Phase 2104 participants (Actual)Interventional2019-03-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for midodrine and Acute Kidney Injury

ArticleYear
AGA Clinical Practice Update on the Evaluation and Management of Acute Kidney Injury in Patients With Cirrhosis: Expert Review.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2022, Volume: 20, Issue:12

    Topics: Acute Kidney Injury; Albumins; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Creat

2022
Emerging hepatic syndromes: pathophysiology, diagnosis and treatment.
    Internal and emergency medicine, 2016, Volume: 11, Issue:7

    Topics: Acute Kidney Injury; Adrenal Insufficiency; Ascites; Creatinine; Evidence-Based Medicine; Hepatorena

2016

Other Studies

4 other studies available for midodrine and Acute Kidney Injury

ArticleYear
Midodrine and albumin versus albumin alone for the secondary prophylaxis of acute kidney injury in a patient with cirrhosis and ascites.
    European journal of gastroenterology & hepatology, 2021, 12-01, Volume: 33, Issue:1S Suppl 1

    Topics: Acute Kidney Injury; Albumins; Ascites; Hepatorenal Syndrome; Humans; Liver Cirrhosis; Midodrine; Pi

2021
Hepatorenal Acute Kidney Injury and the Importance of Raising Mean Arterial Pressure.
    Nephron, 2015, Volume: 131, Issue:3

    Topics: Acute Kidney Injury; Aged; Arterial Pressure; Creatinine; End Stage Liver Disease; Female; Hepatoren

2015
Rifaximin Decreases the Incidence and Severity of Acute Kidney Injury and Hepatorenal Syndrome in Cirrhosis.
    Digestive diseases and sciences, 2016, Volume: 61, Issue:12

    Topics: Acute Kidney Injury; Aged; Anti-Infective Agents; Case-Control Studies; End Stage Liver Disease; Fem

2016
Alcoholic cirrhosis-associated hepatorenal syndrome treated with vasoactive agents.
    Nature clinical practice. Nephrology, 2006, Volume: 2, Issue:3

    Topics: Acute Kidney Injury; Adult; Albumins; Gastrointestinal Hemorrhage; Hepatitis, Alcoholic; Humans; Iso

2006