Page last updated: 2024-10-31

midazolam and Wolff-Parkinson-White Syndrome

midazolam has been researched along with Wolff-Parkinson-White Syndrome in 5 studies

Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.

Wolff-Parkinson-White Syndrome: A form of ventricular pre-excitation characterized by a short PR interval and a long QRS interval with a delta wave. In this syndrome, atrial impulses are abnormally conducted to the HEART VENTRICLES via an ACCESSORY CONDUCTING PATHWAY that is located between the wall of the right or left atria and the ventricles, also known as a BUNDLE OF KENT. The inherited form can be caused by mutation of PRKAG2 gene encoding a gamma-2 regulatory subunit of AMP-activated protein kinase.

Research Excerpts

ExcerptRelevanceReference
" Anesthesia was induced with alfentanil (50 micrograms/kg), midazolam (0."9.08Propofol has no direct effect on sinoatrial node function or on normal atrioventricular and accessory pathway conduction in Wolff-Parkinson-White syndrome during alfentanil/midazolam anesthesia. ( Dobkowski, WB; Klein, G; Murkin, JM; Sharpe, MD; Yee, R, 1995)
"The effects of alfentanil-midazolam anaesthesia upon the electrophysiologic (EP) properties of normal atrioventricular (A-V) and accessory pathway (AP) conduction were studied in eight patients with Wolff-Parkinson-White syndrome during accessory pathway surgical ablation."7.68Alfentanil-midazolam anaesthesia has no electrophysiological effects upon the normal conduction system or accessory pathways in patients with Wolff-Parkinson-White syndrome. ( Dobkowski, WB; Guiraudon, G; Klein, G; Murkin, JM; Sharpe, MD; Yee, R, 1992)
"Sevoflurane was administered to achieve an end-tidal concentration of 2% (1 minimum alveolar concentration), and the study measurements were repeated."6.69Sevoflurane has no effect on sinoatrial node function or on normal atrioventricular and accessory pathway conduction in Wolff-Parkinson-White syndrome during alfentanil/midazolam anesthesia. ( Basta, M; Cuillerier, DJ; Klein, GJ; Krahn, AD; Lee, JK; Sharpe, MD; Yee, R, 1999)
" Anesthesia was induced with alfentanil (50 micrograms/kg), midazolam (0."5.08Propofol has no direct effect on sinoatrial node function or on normal atrioventricular and accessory pathway conduction in Wolff-Parkinson-White syndrome during alfentanil/midazolam anesthesia. ( Dobkowski, WB; Klein, G; Murkin, JM; Sharpe, MD; Yee, R, 1995)
"The effects of alfentanil-midazolam anaesthesia upon the electrophysiologic (EP) properties of normal atrioventricular (A-V) and accessory pathway (AP) conduction were studied in eight patients with Wolff-Parkinson-White syndrome during accessory pathway surgical ablation."3.68Alfentanil-midazolam anaesthesia has no electrophysiological effects upon the normal conduction system or accessory pathways in patients with Wolff-Parkinson-White syndrome. ( Dobkowski, WB; Guiraudon, G; Klein, G; Murkin, JM; Sharpe, MD; Yee, R, 1992)
"Sevoflurane was administered to achieve an end-tidal concentration of 2% (1 minimum alveolar concentration), and the study measurements were repeated."2.69Sevoflurane has no effect on sinoatrial node function or on normal atrioventricular and accessory pathway conduction in Wolff-Parkinson-White syndrome during alfentanil/midazolam anesthesia. ( Basta, M; Cuillerier, DJ; Klein, GJ; Krahn, AD; Lee, JK; Sharpe, MD; Yee, R, 1999)
"The management of Ebstein's anomaly is based on its severity."1.35[Anesthetic management for repair of Ebstein's anomaly with WPW syndrome]. ( Kawahito, S; Kawano, H; Kitahata, H; Nakamura, T; Okada, T; Oshita, S, 2009)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Landsem, LM1
Ross, FJ1
Eisses, MJ1
Nakamura, T1
Kawahito, S1
Kawano, H1
Okada, T1
Kitahata, H1
Oshita, S1
Sharpe, MD3
Dobkowski, WB2
Murkin, JM2
Klein, G2
Yee, R3
Cuillerier, DJ1
Lee, JK1
Basta, M1
Krahn, AD1
Klein, GJ1
Guiraudon, G1

Trials

2 trials available for midazolam and Wolff-Parkinson-White Syndrome

ArticleYear
Propofol has no direct effect on sinoatrial node function or on normal atrioventricular and accessory pathway conduction in Wolff-Parkinson-White syndrome during alfentanil/midazolam anesthesia.
    Anesthesiology, 1995, Volume: 82, Issue:4

    Topics: Adolescent; Adult; Alfentanil; Anesthesia; Atrioventricular Node; Catheter Ablation; Electrophysiolo

1995
Sevoflurane has no effect on sinoatrial node function or on normal atrioventricular and accessory pathway conduction in Wolff-Parkinson-White syndrome during alfentanil/midazolam anesthesia.
    Anesthesiology, 1999, Volume: 90, Issue:1

    Topics: Adult; Alfentanil; Anesthetics, Inhalation; Anesthetics, Intravenous; Atrioventricular Node; Cathete

1999

Other Studies

3 other studies available for midazolam and Wolff-Parkinson-White Syndrome

ArticleYear
A case of midazolam anaphylaxis during a pediatric patient's first anesthetic.
    Journal of clinical anesthesia, 2017, Volume: 43

    Topics: Adolescent; Anaphylaxis; Anesthesia, General; Calcium Chloride; Cardiopulmonary Resuscitation; Cathe

2017
[Anesthetic management for repair of Ebstein's anomaly with WPW syndrome].
    Masui. The Japanese journal of anesthesiology, 2009, Volume: 58, Issue:4

    Topics: Adult; Anesthesia; Arrhythmias, Cardiac; Child, Preschool; Ebstein Anomaly; Echocardiography, Transe

2009
Alfentanil-midazolam anaesthesia has no electrophysiological effects upon the normal conduction system or accessory pathways in patients with Wolff-Parkinson-White syndrome.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1992, Volume: 39, Issue:8

    Topics: Adult; Alfentanil; Anesthesia, Intravenous; Atrial Function, Right; Atrioventricular Node; Blood Pre

1992